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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:bivalirudin pharmacodynamics pathway
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Accession:PW:0002149 term browser browse the term
Definition:The pathway of bivalirudin-target interaction and of the biochemical or physiological responses to drug. The drug is a bivalent direct thrombin inhibitor. Genetic variations can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: SMP:00277


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bivalirudin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00277 NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930
JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00277 NCBI chr 3:91,125,097...91,154,000
Ensembl chr 3:91,124,766...91,157,376
JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00277 NCBI chr 7:132,180,026...132,207,081
Ensembl chr 7:132,180,336...132,208,155
JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00277 NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298
JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00277 NCBI chr17:65,885,498...66,040,026
Ensembl chr17:65,885,658...66,040,040
JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00277 NCBI chr25:32,357,540...32,390,349
Ensembl chr25:32,357,993...32,389,973
JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00277 NCBI chr20:38,726,690...38,738,457
Ensembl chr20:38,726,798...38,739,408
JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00277 NCBI chr25:59,465,610...59,539,022
Ensembl chr25:59,466,378...59,538,872
JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00277 NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327
JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00277 NCBI chr  X:129,090,140...129,315,343
Ensembl chr  X:129,088,611...129,312,909
JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00277 NCBI chr  X:114,618,397...114,650,827
Ensembl chr  X:114,618,639...114,651,365
JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00277 NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405
JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00277 NCBI chr 7:101,106,468...101,114,566
Ensembl chr 7:101,106,483...101,114,662
JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00277 NCBI chr 7:101,148,457...101,157,245
Ensembl chr 7:101,148,058...101,157,111
JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00277 NCBI chr14:21,593,202...21,605,800
Ensembl chr14:21,593,088...21,604,885
JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00277 NCBI chr 7:132,143,514...132,173,189
Ensembl chr 7:132,144,420...132,173,187
JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00277 NCBI chr 8:40,164,391...40,196,627
Ensembl chr 8:40,163,891...40,196,555
JBrowse link
G PLG plasminogen ISO SMPDB SMP:00277 NCBI chr13:88,266,054...88,321,596
Ensembl chr13:88,268,198...88,322,644
JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00277 NCBI chr 5:27,778,553...27,782,639
Ensembl chr 5:27,776,416...27,782,640
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4027
    drug pathway 383
      blood and blood forming organs drug pathway 59
        antithrombotic drug pathway 59
          anticoagulant drug pathway 27
            direct thrombin inhibitor drug pathway 19
              bivalirudin drug pathway 19
                bivalirudin pharmacodynamics pathway 19
paths to the root