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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal macrophage differentiation
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Accession:MP:0008113 term browser browse the term
Definition:atypical production of or inability to produce the large mononuclear phagocytes which differentiate from monocytes, are typically resident in a particular tissue, and capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells


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abnormal macrophage differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qtnf4 C1q and tumor necrosis factor related protein 4 IAGP MGI PMID:33080044 NCBI chr 2:90,713,132...90,720,870
Ensembl chr 2:90,716,204...90,720,869 		JBrowse link
G Casp8 caspase 8 IAGP MGI PMID:15322156 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Cd82 CD82 antigen IAGP MGI PMID:35754722 NCBI chr 2:93,249,447...93,293,295
Ensembl chr 2:93,249,456...93,293,485 		JBrowse link
G Csf1r colony stimulating factor 1 receptor IAGP MGI PMID:16444257 NCBI chr18:61,238,644...61,264,211
Ensembl chr18:61,233,670...61,265,221 		JBrowse link
G Epsti1 epithelial stromal interaction 1 IAGP MGI PMID:29217193 NCBI chr14:78,141,679...78,240,096
Ensembl chr14:78,141,679...78,240,097 		JBrowse link
G Ikzf1 IKAROS family zinc finger 1 IAGP MGI PMID:12871645 NCBI chr11:11,634,970...11,722,930
Ensembl chr11:11,634,980...11,722,926 		JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:15322156 PMID:22624878 PMID:23223452 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IAGP MGI PMID:23223452 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IAGP MGI PMID:23223452 NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248 		JBrowse link
G Mmd monocyte to macrophage differentiation-associated IAGP MGI PMID:33421113 NCBI chr11:90,078,513...90,169,399
Ensembl chr11:90,140,282...90,169,415 		JBrowse link
G Msmp microseminoprotein, prostate associated IAGP MGI PMID:31813573 NCBI chr 4:43,583,216...43,584,494
Ensembl chr 4:43,583,216...43,584,494 		JBrowse link
G Rb1 RB transcriptional corepressor 1 IAGP MGI PMID:16449662 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262 		JBrowse link
G Slc3a2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 IAGP MGI PMID:22624878 NCBI chr19:8,684,931...8,700,733
Ensembl chr19:8,684,246...8,700,733 		JBrowse link
G Spi1 Spi-1 proto-oncogene IAGP MGI PMID:8896458 NCBI chr 2:90,912,750...90,946,104
Ensembl chr 2:90,912,735...90,946,101 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16883
    cellular phenotype 5444
      abnormal cell physiology 4943
        abnormal cell differentiation 1052
          abnormal mononuclear cell differentiation 26
            abnormal macrophage differentiation 14
Path 2
Term Annotations click to browse term
  mammalian phenotype 16883
    immune system phenotype 5668
      abnormal immune system morphology 4064
        abnormal immune system cell morphology 2828
          abnormal leukocyte morphology 2807
            abnormal myeloid leukocyte morphology 1456
              abnormal phagocyte morphology 1204
                abnormal mononuclear phagocyte morphology 868
                  abnormal macrophage morphology 585
                    abnormal macrophage differentiation 14
paths to the root