ONTOLOGY REPORT - ANNOTATIONS
Term: histone H3K36 dimethyltransferase activity
Accession: GO:0140954
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Definition: Catalysis of the reaction: L-lysyl36-[histone H3] + 2 S-adenosyl-L-methionine = 2 H+ + N6,N6-dimethyl-L-lysyl36-[histone H3] + 2 S-adenosyl-L-homocysteine. This reaction is the successive addition of two methyl groups to the lysine residue at position 36 of histone H3, producing histone H3K36me2.
Synonyms: exact_synonym: histone H3K36 dimethylase activity; histone H3K36 mono/dimethylase activity; histone lysine N-dimethyltransferase activity (H3-K36 specific)
broad_synonym: histone H3-K36 dimethylation; histone H3K36 dimethylation
xref: EC:2.1.1.357; RHEA:60308
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LOC100514009
histone-lysine N-methyltransferase SETMAR
enables
ISO
(PMID:16332963)
UniProt
PMID:16332963
NCBI chr13:60,914,412...60,933,064
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LOC100986203
histone-lysine N-methyltransferase SETMAR
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr 3:4,256,539...4,271,593
Ensembl chr 3:4,357,890...4,371,791
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LOC101704237
histone-lysine N-methyltransferase SETMAR
enables
ISO
(PMID:16332963)
UniProt
PMID:16332963
NCBI chrNW_004624773:14,680,571...14,692,583
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LOC101962206
histone-lysine N-methyltransferase SETMAR
enables
ISO
(PMID:16332963)
UniProt
PMID:16332963
NCBI chrNW_004936577:3,761,078...3,771,864
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LOC102020128
histone-lysine N-methyltransferase SETMAR
enables
ISO
(PMID:16332963)
UniProt
PMID:16332963
NCBI chrNW_004955421:9,066,906...9,080,352
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LOC103230910
histone-lysine N-methyltransferase SMYD3
enables
ISO
(MGI:4943402|PMID:16805913)
UniProt
PMID:16805913
MGI:4943402
NCBI chr25:82,794,748...83,531,942
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Nsd1
nuclear receptor-binding SET-domain protein 1
enables
IEA
UniProt
GO_REF:0000003 MGI:2152096
NCBI chr13:55,357,595...55,466,138
Ensembl chr13:55,357,595...55,466,138
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NSD1
nuclear receptor binding SET domain protein 1
enables
IEA
UniProt RHEA
GO_REF:0000003 GO_REF:0000116
NCBI chr 5:177,131,798...177,300,213
Ensembl chr 5:177,131,830...177,300,213
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Nsd2
nuclear receptor binding SET domain protein 2
enables
IEA
UniProt
GO_REF:0000003 MGI:2152096
NCBI chr 5:33,974,286...34,055,310
Ensembl chr 5:33,978,069...34,055,319
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NSD2
nuclear receptor binding SET domain protein 2
enables
IEA
RHEA UniProt
GO_REF:0000003 GO_REF:0000116
NCBI chr 4:1,871,393...1,982,192
Ensembl chr 4:1,871,393...1,982,207
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SETMAR
SET domain and mariner transposase fusion gene
enables
ISO
(PMID:16332963)
UniProt
PMID:16332963
NCBI chr22:40,389,390...40,403,917
Ensembl chr22:40,389,485...40,403,898
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SETMAR
SET domain without mariner transposase fusion
enables
ISO
(PMID:16332963)
UniProt
PMID:16332963
NCBI chr20:13,214,241...13,224,020
Ensembl chr20:13,214,241...13,224,020
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Setmar
SET domain and mariner transposase fusion gene
enables
ISS ISO
GO_REF:0000024 (PMID:16332963)
UniProt RGD
PMID:16332963
GO_REF:0000024
NCBI chr 4:141,046,058...141,058,183
Ensembl chr 4:141,046,069...141,058,197
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Setmar
SET domain without mariner transposase fusion
enables
ISO
MGI
GO_REF:0000119 MGI:4834177
NCBI chr 6:108,042,006...108,054,088
Ensembl chr 6:108,042,006...108,054,083
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SETMAR
SET domain and mariner transposase fusion gene
enables
IEA IDA
(PMID:16332963)
UniProt RHEA
PMID:16332963
GO_REF:0000003 GO_REF:0000116
NCBI chr 3:4,303,369...4,317,265
Ensembl chr 3:4,303,332...4,317,265
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Smyd3
SET and MYND domain containing 3
enables
ISO
(MGI:4943402|PMID:16805913)
UniProt
PMID:16805913
MGI:4943402
NCBI chrNW_004624771:13,149,547...13,943,352
Ensembl chrNW_004624771:13,149,649...13,943,137
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SMYD3
SET and MYND domain containing 3
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr10:18,267,598...19,019,520
Ensembl chr10:18,267,189...19,019,642
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Smyd3
SET and MYND domain containing 3
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936526:4,536,157...5,218,883
Ensembl chrNW_004936526:4,536,142...5,218,657
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SMYD3
SET and MYND domain containing 3
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr 7:36,561,080...37,250,336
Ensembl chr 7:36,565,901...37,250,578
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SMYD3
SET and MYND domain containing 3
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr 1:221,371,348...222,125,774
Ensembl chr 1:226,737,960...227,481,191
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Smyd3
SET and MYND domain containing 3
enables
ISO
(MGI:4943402|PMID:16805913)
UniProt
PMID:16805913
MGI:4943402
NCBI chrNW_004955406:8,768,365...9,417,612
Ensembl chrNW_004955406:8,768,588...9,417,525
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Smyd3
SET and MYND domain containing 3
enables
ISO
(MGI:4943402|PMID:16805913)
RGD
PMID:16805913
MGI:4943402
NCBI chr13:90,709,263...91,266,209
Ensembl chr13:90,709,270...91,266,253
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Smyd3
SET and MYND domain containing 3
enables
IDA
(MGI:4943402|PMID:16805913)
UniProt
PMID:16805913
MGI:4943402
NCBI chr 1:178,779,525...179,345,618
Ensembl chr 1:178,779,525...179,345,606
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SMYD3
SET and MYND domain containing 3
enables
ISS IEA
UniProt Ensembl
GO_REF:0000024 GO_REF:0000107
NCBI chr 1:245,749,347...246,507,279
Ensembl chr 1:245,749,342...246,507,312
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