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ONTOLOGY REPORT - ANNOTATIONS

Term:NAD-dependent histone H3K18 deacetylase activity
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Accession:GO:0097372 term browser browse the term
Definition:Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 18) + H2O = histone H3 L-lysine (position 18) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 18 of the histone H3 protein.
Synonyms:exact_synonym: NAD-dependent histone H3-K18 deacetylase activity;   NAD-dependent histone deacetylase activity (H3-K18 specific)


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NAD-dependent histone H3K18 deacetylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt6 sirtuin 6 enables IDA
ISO		 (MGI:7258357|PMID:31002797) UniProt
MGI		 PMID:31002797 GO_REF:0000119 MGI:4834177 MGI:7258357 NCBI chr10:81,457,621...81,463,631
Ensembl chr10:81,457,619...81,463,631 		JBrowse link
G Sirt7 sirtuin 7 enables IMP
ISO
IBA		 (MGI:5789069|PMID:27225932), (MGI:6377981|PMID:31226208), (MGI:6378020|PMID:31256246) UniProt
MGI
GO_Central		 PMID:27225932 PMID:31226208 PMID:31256246 GO_REF:0000033 GO_REF:0000119 MGI:4834177 MGI:5789069 MGI:6377981 MGI:6378020 NCBI chr11:120,509,197...120,515,840
Ensembl chr11:120,509,198...120,516,066 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 28831
    catalytic activity 5721
      catalytic activity, acting on a protein 2360
        protein lysine deacetylase activity 23
          histone deacetylase activity 23
            histone H3K deacetylase activity 4
              NAD-dependent histone H3K18 deacetylase activity 2
Path 2
Term Annotations click to browse term
  molecular_function 28831
    catalytic activity 5721
      hydrolase activity 2454
        hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 144
          hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 87
            histone deacetylase activity 23
              NAD-dependent histone deacetylase activity 5
                NAD-dependent histone H3K18 deacetylase activity 2
paths to the root