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Ontology Browser

Term:
NAD-dependent histone deacetylase activity (GO:0017136)
Annotations: Rat: (6) Mouse: (5) Human: (5) Chinchilla: (4) Bonobo: (6) Dog: (7) Squirrel: (6) Pig: (6) Naked Mole-rat: (6) Green Monkey: (6)
Parent Terms Term With Siblings Child Terms
histone H3K deacetylase activity +   
histone H4K deacetylase activity +   
NAD-dependent histone deacetylase activity +   
Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from a histone.
NAD-independent histone deacetylase activity 

Synonyms
Related Synonyms: SIR2
Definition Sources: PMID:28450737

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