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ONTOLOGY REPORT - ANNOTATIONS

Term:'de novo' UMP biosynthetic process
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Accession:GO:0044205 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD+ or oxygen.
Synonyms:exact_synonym: 'de novo' UMP biosynthesis


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'de novo' UMP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase involved_in IEA
IDA		 (PMID:25678555) Ensembl
MGI
UniProt		 PMID:25678555 GO_REF:0000041 GO_REF:0000107 NCBI chr 2:27,217,369...27,243,943
Ensembl chr 2:27,217,369...27,243,943 		JBrowse link
G DHODH dihydroorotate dehydrogenase (quinone) involved_in IEA Ensembl
UniProt		 GO_REF:0000041 GO_REF:0000107 NCBI chr16:72,008,744...72,027,659
Ensembl chr16:72,008,588...72,027,664 		JBrowse link
G UMPS uridine monophosphate synthetase involved_in IEA Ensembl
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 NCBI chr 3:124,730,452...124,749,273
Ensembl chr 3:124,730,433...124,749,273 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19670
    metabolic process 12471
      organic substance metabolic process 11974
        organic cyclic compound metabolic process 7070
          pyrimidine-containing compound metabolic process 95
            pyrimidine nucleotide metabolic process 57
              pyrimidine nucleotide biosynthetic process 35
                pyrimidine ribonucleotide biosynthetic process 25
                  UMP biosynthetic process 11
                    'de novo' UMP biosynthetic process 3
Path 2
Term Annotations click to browse term
  biological_process 19670
    metabolic process 12471
      organic substance metabolic process 11974
        organic cyclic compound metabolic process 7070
          nucleobase-containing compound metabolic process 6539
            nucleobase-containing small molecule metabolic process 744
              nucleoside phosphate metabolic process 666
                nucleoside monophosphate metabolic process 85
                  nucleoside monophosphate biosynthetic process 44
                    pyrimidine nucleoside monophosphate biosynthetic process 16
                      pyrimidine ribonucleoside monophosphate biosynthetic process 12
                        UMP biosynthetic process 11
                          'de novo' UMP biosynthetic process 3
paths to the root