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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of T-helper 17 cell differentiation
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Accession:GO:2000319 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of T-helper 17 cell differentiation.
Synonyms:related_synonym: regulation of T-helper 17 cell development


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regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL20 C-C motif chemokine ligand 20 NOT|involved_in ISO (PMID:19050256) UniProt PMID:19050256 NCBI chr10:113,815,099...113,836,562
Ensembl chr10:113,832,573...113,835,736
JBrowse link
G CCR6 C-C motif chemokine receptor 6 NOT|involved_in ISO (PMID:19050256) UniProt PMID:19050256 NCBI chr13:94,865,480...94,894,331
Ensembl chr13:94,865,936...94,894,315
JBrowse link
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL2 achaete-scute family bHLH transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:2,075,629...2,080,462
Ensembl chr 1:2,076,851...2,077,432
JBrowse link
G FOXP3 forkhead box P3 involved_in ISO (PMID:23169781) UniProt PMID:23169781 NCBI chr  X:46,349,890...46,365,133 JBrowse link
G FOXP3 forkhead box P3 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr  X:46,346,754...46,356,928 JBrowse link
G IL2 interleukin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:69,729,635...69,736,279
Ensembl chr 7:69,730,282...69,734,969
JBrowse link
G IL4 interleukin 4 acts_upstream_of_or_within ISO (PMID:18792410) MGI PMID:18792410 NCBI chr23:35,492,158...35,501,349
Ensembl chr23:35,492,939...35,501,258
JBrowse link
G LOC103230557 roquin-1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:55,167,418...55,258,964
Ensembl chr25:55,167,077...55,279,088
JBrowse link
G RC3H2 ring finger and CCCH-type domains 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:15,230,206...15,283,253
Ensembl chr12:15,238,124...15,280,689
JBrowse link
G SMAD7 SMAD family member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:31,993,543...32,024,088
Ensembl chr18:31,993,681...32,024,850
JBrowse link
G TBX21 T-box transcription factor 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:68,131,258...68,145,579
Ensembl chr16:68,131,536...68,144,415
JBrowse link
G ZBTB7B zinc finger and BTB domain containing 7B involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23034280) Ensembl
MGI
PMID:23034280 GO_REF:0000107 NCBI chr20:8,812,514...8,829,128
Ensembl chr20:8,812,351...8,817,286
JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:95,388,469...95,398,305
Ensembl chr20:95,388,477...95,397,960
JBrowse link
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD69 CD69 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:9,659,154...9,666,342
Ensembl chr11:9,659,029...9,665,914
JBrowse link
G JAK3 Janus kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:16,301,760...16,323,343
Ensembl chr 6:16,300,525...16,322,859
JBrowse link
G LGALS1 galectin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:20,379,144...20,383,303
Ensembl chr19:20,379,003...20,383,464
JBrowse link
G LOC103243413 signal transducer and activator of transcription 5B involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:63,997,486...64,070,392
Ensembl chr16:63,997,441...64,070,445
JBrowse link
G LOXL3 lysyl oxidase like 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:32,722,588...32,745,480
Ensembl chr14:32,725,112...32,745,004
JBrowse link
G STAT5A signal transducer and activator of transcription 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:63,959,265...63,986,627
Ensembl chr16:63,960,515...63,985,026
JBrowse link
G TBX21 T-box transcription factor 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:68,131,258...68,145,579
Ensembl chr16:68,131,536...68,144,415
JBrowse link
G TNFSF18 TNF superfamily member 18 involved_in ISO (PMID:24107315) UniProt PMID:24107315 NCBI chr25:56,105,757...56,118,249
Ensembl chr25:56,106,584...56,118,758
JBrowse link
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MALT1 MALT1 paracaspase involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:20,984,985...21,064,198
Ensembl chr18:20,985,819...21,054,554
JBrowse link
G NFKBID NFKB inhibitor delta involved_in ISO (PMID:25282160) UniProt PMID:25282160 NCBI chr 6:30,800,122...30,812,991
Ensembl chr 6:30,799,204...30,811,141
JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:79,044,624...79,077,736
Ensembl chr22:79,044,619...79,055,776
JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in ISO (PMID:26098997) UniProt PMID:26098997 NCBI chr25:84,431,436...84,463,387
Ensembl chr25:84,434,527...84,463,249
JBrowse link
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRD2 bromodomain containing 2 involved_in ISO (PMID:28262505) UniProt PMID:28262505 NCBI chr17:39,113,519...39,126,267 JBrowse link
G BRD2 bromodomain containing 2 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr17:39,114,700...39,122,051 JBrowse link
G BRD4 bromodomain containing 4 involved_in ISO (PMID:28262505) UniProt PMID:28262505 NCBI chr 6:13,836,332...13,883,459
Ensembl chr 6:13,836,324...13,873,877
JBrowse link
G EP300 E1A binding protein p300 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:23,634,132...23,726,095
Ensembl chr19:23,634,571...23,724,979
JBrowse link
G IL23A interleukin 23 subunit alpha involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr11:52,289,486...52,296,735
Ensembl chr11:52,295,106...52,297,244
JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:87,679,656...87,778,767
Ensembl chr15:87,679,077...87,779,102
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19801
    regulation of biological process 11755
      regulation of immune system process 1670
        regulation of immune response 985
          regulation of T-helper cell differentiation 49
            regulation of T-helper 17 cell differentiation 30
              negative regulation of T-helper 17 cell differentiation + 18
              positive regulation of T-helper 17 cell differentiation + 10
              regulation of T-helper 17 cell lineage commitment + 14
Path 2
Term Annotations click to browse term
  biological_process 19801
    cellular process 19323
      cellular developmental process 4576
        cell differentiation 4575
          cell development 3261
            hemopoiesis 1051
              leukocyte differentiation 683
                mononuclear cell differentiation 554
                  lymphocyte differentiation 453
                    T cell differentiation 338
                      T cell differentiation involved in immune response 101
                        alpha-beta T cell differentiation involved in immune response 92
                          CD4-positive, alpha-beta T cell differentiation involved in immune response 90
                            T-helper cell differentiation 88
                              regulation of T-helper cell differentiation 49
                                regulation of T-helper 17 cell differentiation 30
                                  negative regulation of T-helper 17 cell differentiation + 18
                                  positive regulation of T-helper 17 cell differentiation + 10
                                  regulation of T-helper 17 cell lineage commitment + 14
paths to the root