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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of ceramide biosynthetic process
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Accession:GO:2000303 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of a ceramide biosynthetic process.
Synonyms:exact_synonym: regulation of ceramide anabolism;   regulation of ceramide biosynthesis;   regulation of ceramide formation;   regulation of ceramide synthesis



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regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 involved_in
acts_upstream_of
IEA
ISO
(PMID:31880535) UniProt
MGI
Ensembl
PMID:31880535 GO_REF:0000104 GO_REF:0000107 GO_REF:0000117 NCBI chr37:509,592...521,511
Ensembl chr37:511,149...522,865
JBrowse link
G ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 involved_in IEA UniProt GO_REF:0000104 GO_REF:0000117 NCBI chr10:203,750...206,247 JBrowse link
G ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 involved_in
acts_upstream_of
IEA
ISO
(PMID:31880535) Ensembl
MGI
UniProt
PMID:31880535 GO_REF:0000104 GO_REF:0000107 GO_REF:0000117 NCBI chr 9:22,594,425...22,601,108
Ensembl chr 9:22,594,480...22,599,999
JBrowse link
G PAQR4 progestin and adipoQ receptor family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:38,210,476...38,213,689
Ensembl chr 6:38,210,481...38,213,670
JBrowse link
G PRKCD protein kinase C delta involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr20:36,723,491...36,751,982
Ensembl chr20:36,723,809...36,752,191
JBrowse link
G SAMD8 sterile alpha motif domain containing 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:25,375,127...25,424,792
Ensembl chr 4:25,374,837...25,421,075
JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:25691431) MGI
Ensembl
PMID:25691431 GO_REF:0000107 NCBI chr37:509,592...521,511
Ensembl chr37:511,149...522,865
JBrowse link
G ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 acts_upstream_of_or_within ISO (PMID:25691431) MGI PMID:25691431 NCBI chr10:203,750...206,247 JBrowse link
G ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:25691431) MGI
Ensembl
PMID:25691431 GO_REF:0000107 NCBI chr 9:22,594,425...22,601,108
Ensembl chr 9:22,594,480...22,599,999
JBrowse link
G SPHK1 sphingosine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:4,311,698...4,314,773
Ensembl chr 9:4,311,683...4,314,483
JBrowse link
positive regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCN1 cellular communication network factor 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:19364818) MGI
Ensembl
PMID:19364818 GO_REF:0000107 NCBI chr 6:62,443,285...62,446,246
Ensembl chr 6:62,443,675...62,445,994
JBrowse link
G ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISO (PMID:21177474) UniProt PMID:21177474 NCBI chr 9:1,887,093...1,894,728
Ensembl chr 9:1,887,201...1,897,473
JBrowse link
G PLA2G6 phospholipase A2 group VI ISO RGD PMID:18936091 RGD:6482750 NCBI chr10:26,499,033...26,559,533
Ensembl chr10:26,509,695...26,634,087
JBrowse link
G PRKCD protein kinase C delta involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:36,723,491...36,751,982
Ensembl chr20:36,723,809...36,752,191
JBrowse link
G SIRT3 sirtuin 3 involved_in ISO (PMID:26620563) UniProt PMID:26620563 NCBI chr18:25,369,183...25,388,126
Ensembl chr18:25,369,382...25,388,118
JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 ISO RGD PMID:20096352 RGD:10041064 NCBI chr 5:81,089,657...81,172,173
Ensembl chr 5:81,142,888...81,172,189
JBrowse link
G SPHK2 sphingosine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:107,681,425...107,689,790
Ensembl chr 1:107,680,599...107,689,707
JBrowse link
G ZNF750 zinc finger protein 750 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:37115925) Ensembl
MGI
PMID:37115925 GO_REF:0000107

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17101
    regulation of biological process 11454
      regulation of cellular process 11121
        regulation of cellular component biogenesis 1137
          regulation of sphingolipid biosynthetic process 16
            regulation of ceramide biosynthetic process 14
              negative regulation of ceramide biosynthetic process + 4
              positive regulation of ceramide biosynthetic process + 8
              regulation of glucosylceramide biosynthetic process + 0
Path 2
Term Annotations click to browse term
  biological_process 17101
    cellular process 16595
      metabolic process 10708
        primary metabolic process 9413
          lipid metabolic process 1290
            membrane lipid metabolic process 188
              membrane lipid biosynthetic process 126
                sphingolipid biosynthetic process 87
                  regulation of sphingolipid biosynthetic process 16
                    regulation of ceramide biosynthetic process 14
                      negative regulation of ceramide biosynthetic process + 4
                      positive regulation of ceramide biosynthetic process + 8
                      regulation of glucosylceramide biosynthetic process + 0
paths to the root