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ONTOLOGY REPORT - ANNOTATIONS

Term:sphingolipid biosynthetic process
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Accession:GO:0030148 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
Synonyms:exact_synonym: sphingolipid anabolism;   sphingolipid biosynthesis;   sphingolipid formation;   sphingolipid synthesis
 xref: MetaCyc:PWY-5129


show annotations for term's descendants           Sort by:
sphingolipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer1 alkaline ceramidase 1 involved_in ISO (PMID:17713573) RGD PMID:17713573 NCBI chr 9:1,794,340...1,824,432
Ensembl chr 9:1,793,139...1,824,434 		JBrowse link
G Atg7 autophagy related 7 acts_upstream_of ISO MGI:2176073|MGI:3587769 (MGI:5613260|PMID:25332431) RGD PMID:25332431 MGI:5613260 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Cerkl ceramide kinase-like acts_upstream_of_or_within ISO MGI:5461515 (MGI:5571022|PMID:23501591) RGD PMID:23501591 MGI:5571022 NCBI chr 3:64,238,714...64,344,695
Ensembl chr 3:64,237,522...64,340,675 		JBrowse link
G Cers1 ceramide synthase 1 involved_in ISO (PMID:12105227) RGD PMID:12105227 NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,104,466...19,112,519 		JBrowse link
G Cers2 ceramide synthase 2 acts_upstream_of_or_within ISO (MGI:3696894|PMID:15823095) RGD PMID:15823095 MGI:3696894 NCBI chr 2:182,890,527...182,898,805
Ensembl chr 2:182,890,493...182,933,314 		JBrowse link
G Cers3 ceramide synthase 3 acts_upstream_of_or_within ISO (MGI:3692343|PMID:16753040) RGD PMID:16753040 MGI:3692343 NCBI chr 1:120,316,930...120,422,926
Ensembl chr 1:120,318,212...120,422,902 		JBrowse link
G Cers4 ceramide synthase 4 acts_upstream_of_or_within ISO (MGI:3696894|PMID:15823095) RGD PMID:15823095 MGI:3696894 NCBI chr12:2,851,784...2,890,244
Ensembl chr12:2,851,784...2,886,828 		JBrowse link
G Cers5 ceramide synthase 5 acts_upstream_of_or_within ISO (MGI:3696894|PMID:15823095) RGD PMID:15823095 MGI:3696894 NCBI chr 7:130,859,993...130,897,979
Ensembl chr 7:130,859,990...130,897,947 		JBrowse link
G Cers6 ceramide synthase 6 acts_upstream_of_or_within ISO (MGI:3696894|PMID:15823095) RGD PMID:15823095 MGI:3696894 NCBI chr 3:53,630,637...53,879,692
Ensembl chr 3:53,630,959...53,876,848 		JBrowse link
G Degs2 delta(4)-desaturase, sphingolipid 2 acts_upstream_of_or_within ISO SGD:S000002705 (MGI:3505861|PMID:11937514) RGD PMID:11937514 MGI:3505861 NCBI chr 6:127,596,063...127,613,293
Ensembl chr 6:127,596,071...127,613,293 		JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 involved_in ISO
IBA		 (PMID:20937905)
PMID:21873635
(MGI:4944052|PMID:20253178)		 RGD PMID:20253178 PMID:20937905 PMID:21873635 MGI:4944052, RGD:13792537 NCBI chr 5:131,961,478...131,965,961
Ensembl chr 5:131,961,322...131,965,958 		JBrowse link
G Elovl2 ELOVL fatty acid elongase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:23,544,598...23,584,855
Ensembl chr17:23,544,568...23,584,848 		JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:244,997,287...245,001,115
Ensembl chr 1:244,997,287...245,001,115 		JBrowse link
G Elovl4 ELOVL fatty acid elongase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:84,702,916...84,729,466
Ensembl chr 8:84,702,362...84,729,697 		JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:78,790,846...78,857,307
Ensembl chr 8:78,790,846...78,857,284 		JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186 		JBrowse link
G Elovl7 ELOVL fatty acid elongase 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:39,789,229...39,858,579
Ensembl chr 2:39,789,250...39,856,845 		JBrowse link
G Hacd1 3-hydroxyacyl-CoA dehydratase 1 involved_in ISO
IBA		 UniProtKB:P40857 (PMID:18554506)
PMID:21873635		 RGD PMID:18554506 PMID:21873635 RGD:13792537 NCBI chr17:77,081,508...77,106,114
Ensembl chr17:77,083,740...77,106,073 		JBrowse link
G Hacd2 3-hydroxyacyl-CoA dehydratase 2 involved_in ISO
IBA		 UniProtKB:P40857 (PMID:18554506)
PMID:21873635		 RGD PMID:18554506 PMID:21873635 RGD:13792537 NCBI chr11:65,667,671...65,762,903
Ensembl chr11:65,670,281...65,762,889 		JBrowse link
G Hacd3 3-hydroxyacyl-CoA dehydratase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:65,501,240...65,538,507
Ensembl chr 8:65,501,240...65,538,507 		JBrowse link
G Hacd4 3-hydroxyacyl-CoA dehydratase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:102,887,597...102,915,376
Ensembl chr 5:102,887,588...102,915,338 		JBrowse link
G Kdsr 3-ketodihydrosphingosine reductase acts_upstream_of_or_within
involved_in		 ISO
IBA		 SGD:S000000469 (MGI:3522414|PMID:15328338)
PMID:21873635		 RGD PMID:15328338 PMID:21873635 MGI:3522414, RGD:13792537 NCBI chr13:22,862,117...22,894,118
Ensembl chr13:22,862,117...22,894,108 		JBrowse link
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:48,243,365...48,253,316
Ensembl chr 9:48,237,572...48,253,211 		JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:1,247,869...1,250,999
Ensembl chr 7:1,246,479...1,250,907 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:83,590,052...83,596,035
Ensembl chr10:83,590,071...83,598,620 		JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 acts_upstream_of_or_within ISO (PMID:25332431) RGD PMID:25332431 NCBI chr17:11,877,249...11,916,295
Ensembl chr17:11,877,249...11,916,295 		JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:25332431)
(PMID:26573920)
(MGI:5917779|PMID:28698261)		 UniProt
RGD		 PMID:25332431 PMID:26573920 PMID:28698261 GO_REF:0000024 MGI:5917779 NCBI chr 6:106,948,682...107,031,532
Ensembl chr 6:106,950,949...107,031,542 		JBrowse link
G Sptssb serine palmitoyltransferase, small subunit B acts_upstream_of_or_within ISO MGI:5689843 (MGI:5689923|PMID:26438849) RGD PMID:26438849 MGI:5689923 NCBI chr 2:154,133,728...154,162,127
Ensembl chr 2:154,133,733...154,163,120 		JBrowse link
ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agk acylglycerol kinase involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:3054595|PMID:15252046)		 RGD PMID:15252046 PMID:21873635 MGI:3054595, RGD:13792537 NCBI chr 4:69,114,850...69,193,989
Ensembl chr 4:69,114,269...69,193,934 		JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:3789553|PMID:17403930)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:17403930 GO_REF:0000024 GO_REF:0000107 MGI:3789553 NCBI chr10:53,863,060...53,874,938
Ensembl chr10:53,863,060...53,874,938 		JBrowse link
G Aloxe3 arachidonate lipoxygenase 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5488571|PMID:22832496)		 UniProt
RGD		 PMID:22832496 GO_REF:0000024 MGI:5488571 NCBI chr10:53,830,219...53,854,328
Ensembl chr10:53,831,264...53,854,328 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 involved_in ISO
ISS		 (PMID:12764132), (PMID:12815059)
GO_REF:0000024		 RGD
UniProt		 PMID:12764132 PMID:12815059 GO_REF:0000024 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233 		JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in ISO
IDA		 (PMID:11278489), (PMID:17475390)
(MGI:6274955|PMID:21613224)
PMID:15123644		 RGD PMID:11278489 PMID:17475390 PMID:21613224 PMID:15123644 PMID:11278489 MGI:6274955, RGD:13838793, RGD:13838803 NCBI chr 1:229,865,662...229,973,253
Ensembl chr 1:229,865,662...229,939,162 		JBrowse link
G Cers1 ceramide synthase 1 involved_in ISO
IBA		 (PMID:12105227), (PMID:12869556), (PMID:15823095), (PMID:17548428), (PMID:18541923), (PMID:22922758), (PMID:24782409)
PMID:21873635
(MGI:3696321|PMID:16951403), (MGI:3764760|PMID:17977534), (MGI:5008665|PMID:21625621), (MGI:5755322|PMID:26620563), (MGI:6380950|PMID:30605666)		 RGD PMID:12105227 PMID:12869556 PMID:15823095 PMID:16951403 PMID:17548428 More... MGI:3696321 MGI:3764760 MGI:5008665 MGI:5755322 MGI:6380950, RGD:13792537 NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,104,466...19,112,519 		JBrowse link
G Cers2 ceramide synthase 2 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:17977534), (PMID:18165233), (PMID:29632068)
PMID:21873635
(MGI:4421488|PMID:19801672), (MGI:5755322|PMID:26620563)
(MGI:3696894|PMID:15823095)		 RGD PMID:15823095 PMID:17977534 PMID:18165233 PMID:19801672 PMID:26620563 More... MGI:3696894 MGI:4421488 MGI:5755322, RGD:13792537 NCBI chr 2:182,890,527...182,898,805
Ensembl chr 2:182,890,493...182,933,314 		JBrowse link
G Cers3 ceramide synthase 3 involved_in ISO
IBA		 (PMID:17977534), (PMID:22038835), (PMID:23754960)
PMID:21873635
(MGI:5303015|PMID:22038835)		 RGD PMID:17977534 PMID:22038835 PMID:23754960 PMID:21873635 MGI:5303015, RGD:13792537 NCBI chr 1:120,316,930...120,422,926
Ensembl chr 1:120,318,212...120,422,902 		JBrowse link
G Cers4 ceramide synthase 4 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:17977534), (PMID:29632068)
PMID:21873635
(MGI:2679796|PMID:12912983), (MGI:3696894|PMID:15823095)		 RGD PMID:12912983 PMID:15823095 PMID:17977534 PMID:29632068 PMID:21873635 MGI:2679796 MGI:3696894, RGD:13792537 NCBI chr12:2,851,784...2,890,244
Ensembl chr12:2,851,784...2,886,828 		JBrowse link
G Cers5 ceramide synthase 5 involved_in ISO
IBA		 (PMID:16951403), (PMID:29632068)
PMID:21873635
(MGI:3696624|PMID:16100120), (MGI:3722529|PMID:17609214), (MGI:3764760|PMID:17977534)		 RGD PMID:16100120 PMID:16951403 PMID:17609214 PMID:17977534 PMID:29632068 More... MGI:3696624 MGI:3722529 MGI:3764760, RGD:13792537 NCBI chr 7:130,859,993...130,897,979
Ensembl chr 7:130,859,990...130,897,947 		JBrowse link
G Cers6 ceramide synthase 6 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:17609214), (PMID:17977534)
PMID:21873635
(MGI:5513027|PMID:23760501), (MGI:5755322|PMID:26620563)
(MGI:3696894|PMID:15823095)		 RGD PMID:15823095 PMID:17609214 PMID:17977534 PMID:23760501 PMID:26620563 More... MGI:3696894 MGI:5513027 MGI:5755322, RGD:13792537 NCBI chr 3:53,630,637...53,879,692
Ensembl chr 3:53,630,959...53,876,848 		JBrowse link
G Cyp4f17 cytochrome P450, family 4, subfamily f, polypeptide 17 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:11,518,985...11,536,208
Ensembl chr 7:11,433,371...11,536,181 		JBrowse link
G Cyp4f39 cytochrome P450, family 4, subfamily f, polypeptide 39 involved_in IBA
ISO		 PMID:21873635
(PMID:26056268)		 RGD PMID:26056268 PMID:21873635 RGD:13792537 NCBI chr 7:11,426,806...11,505,553
Ensembl chr 7:11,433,371...11,536,181 		JBrowse link
G Degs1 delta(4)-desaturase, sphingolipid 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:3529540 (MGI:5466789|PMID:22984457)
PMID:21873635		 RGD PMID:22984457 PMID:21873635 MGI:5466789, RGD:13792537 NCBI chr13:93,946,154...93,953,677
Ensembl chr13:93,946,157...93,953,664 		JBrowse link
G Degs1l1 delta(4)-desaturase, sphingolipid 1 like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:92,772,654...92,818,811
Ensembl chr13:92,772,649...92,818,574 		JBrowse link
G Degs1l2 delta(4)-desaturase, sphingolipid 1 like 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:92,831,549...92,839,257
Ensembl chr13:92,831,537...92,839,246 		JBrowse link
G Degs2 delta(4)-desaturase, sphingolipid 2 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:3694278|PMID:16571104)
PMID:21873635		 RGD PMID:16571104 PMID:21873635 MGI:3694278, RGD:13792537 NCBI chr 6:127,596,063...127,613,293
Ensembl chr 6:127,596,071...127,613,293 		JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 involved_in ISO (MGI:5532629|PMID:23689133) RGD PMID:23689133 MGI:5532629 NCBI chr 5:131,961,478...131,965,961
Ensembl chr 5:131,961,322...131,965,958 		JBrowse link
G Fa2h fatty acid 2-hydroxylase involved_in ISO
ISS		 (PMID:15337768)
(MGI:6245295|PMID:22517924)
GO_REF:0000024		 RGD
UniProt		 PMID:15337768 PMID:22517924 GO_REF:0000024 MGI:6245295 NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153 		JBrowse link
G Gba1 glucosylceramidase beta 1 involved_in ISO (PMID:19279011) RGD PMID:19279011 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G P2rx1 purinergic receptor P2X 1 acts_upstream_of_or_within ISO (MGI:3640029|PMID:16325464) RGD PMID:16325464 MGI:3640029 NCBI chr10:57,618,586...57,633,648
Ensembl chr10:57,618,586...57,633,623 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (MGI:3640029|PMID:16325464) RGD PMID:16325464 MGI:3640029 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Pnpla1 patatin-like phospholipase domain containing 1 involved_in ISO (PMID:27751867)
(MGI:5882269|PMID:27751867)		 RGD PMID:27751867 MGI:5882269 NCBI chr20:6,917,993...6,952,157
Ensembl chr20:6,917,931...6,952,375 		JBrowse link
G Samd8 sterile alpha motif domain containing 8 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:19506037)
PMID:21873635
MGI:5749225 (MGI:5632043|PMID:25605874), (MGI:5707904|PMID:25667419)		 RGD PMID:19506037 PMID:25605874 PMID:25667419 PMID:21873635 MGI:5632043 MGI:5707904, RGD:13792537 NCBI chr15:2,512,104...2,562,368
Ensembl chr15:2,512,105...2,515,379
Ensembl chr15:2,512,105...2,515,379 		JBrowse link
G Sgms1 sphingomyelin synthase 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:25605874)
(MGI:5632043|PMID:25605874)		 RGD PMID:25605874 PMID:21873635 MGI:5632043, RGD:13792537 NCBI chr 1:229,996,673...230,259,591
Ensembl chr 1:229,998,119...230,259,603 		JBrowse link
G Sgms2 sphingomyelin synthase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
MGI:4818459 (MGI:5632043|PMID:25605874)
PMID:21873635		 Ensembl
RGD		 PMID:25605874 PMID:21873635 GO_REF:0000107 MGI:5632043, RGD:13792537 NCBI chr 2:219,889,809...219,967,704
Ensembl chr 2:219,893,572...219,967,546 		JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 involved_in IMP
ISO
IBA		 (PMID:17303575), (PMID:18815062), (PMID:19279011), (PMID:20807762), (PMID:33163980), (PMID:8706124)
(MGI:7327228|PMID:35705808), (MGI:82530|PMID:8706124)
PMID:21873635		 RGD PMID:8706124 PMID:17303575 PMID:18815062 PMID:19279011 PMID:20807762 More... MGI:7327228 MGI:82530, RGD:1601344, RGD:13792537 NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794 		JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:12473648 PMID:21873635 RGD:1581395, RGD:13792537 NCBI chr20:44,986,229...44,989,343
Ensembl chr20:44,986,231...44,989,441 		JBrowse link
G Smpd4 sphingomyelin phosphodiesterase 4 involved_in ISO
IBA		 (PMID:16517606), (PMID:25180167)
(MGI:6450503|PMID:25180167)
PMID:21873635		 RGD PMID:16517606 PMID:25180167 PMID:21873635 MGI:6450503, RGD:13792537 NCBI chr11:83,362,534...83,386,257
Ensembl chr11:83,362,534...83,386,250 		JBrowse link
G Smpd5 sphingomyelin phosphodiesterase 5 involved_in ISO (MGI:6450238|PMID:21183079) RGD PMID:21183079 MGI:6450238 NCBI chr 7:108,009,182...108,011,767
Ensembl chr 7:108,009,173...108,011,763 		JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:25691431)
MGI:3815115 (MGI:3814228|PMID:16216550)		 RGD PMID:16216550 PMID:25691431 PMID:21873635 MGI:3814228, RGD:13792537 NCBI chr17:11,877,249...11,916,295
Ensembl chr17:11,877,249...11,916,295 		JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 PMID:21873635
GO_REF:0000107
(PMID:25691431)
MGI:3815117 (MGI:3814228|PMID:16216550)		 Ensembl
RGD		 PMID:16216550 PMID:25691431 PMID:21873635 GO_REF:0000107 MGI:3814228, RGD:13792537 NCBI chr 6:106,948,682...107,031,532
Ensembl chr 6:106,950,949...107,031,542 		JBrowse link
G Sptlc3 serine palmitoyltransferase, long chain base subunit 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:126,847,878...126,978,010
Ensembl chr 3:126,847,878...126,978,010 		JBrowse link
G Sptssa serine palmitoyltransferase, small subunit A involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:25691431)		 RGD PMID:25691431 PMID:21873635 RGD:13792537 NCBI chr 6:72,144,714...72,156,130
Ensembl chr 6:72,144,714...72,156,214 		JBrowse link
G Sptssb serine palmitoyltransferase, small subunit B acts_upstream_of_or_within ISO MGI:5689843 (MGI:5689923|PMID:26438849) RGD PMID:26438849 MGI:5689923 NCBI chr 2:154,133,728...154,162,127
Ensembl chr 2:154,133,733...154,163,120 		JBrowse link
G Tlcd3b TLC domain containing 3B acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:5490837|PMID:23275342)
PMID:21873635		 RGD PMID:23275342 PMID:21873635 MGI:5490837, RGD:13792537 NCBI chr 1:181,421,104...181,439,744
Ensembl chr 1:181,422,830...181,439,743 		JBrowse link
ceramide phosphoethanolamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Samd8 sterile alpha motif domain containing 8 acts_upstream_of_or_within ISO (MGI:5707904|PMID:25667419) RGD PMID:25667419 MGI:5707904 NCBI chr15:2,512,104...2,562,368
Ensembl chr15:2,512,105...2,515,379
Ensembl chr15:2,512,105...2,515,379 		JBrowse link
G Sgms2 sphingomyelin synthase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:5707904|PMID:25667419)		 Ensembl
RGD		 PMID:25667419 GO_REF:0000107 MGI:5707904 NCBI chr 2:219,889,809...219,967,704
Ensembl chr 2:219,893,572...219,967,546 		JBrowse link
galactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3galt1 Beta-1,3-galactosyltransferase 1 involved_in ISO (PMID:9582303) RGD PMID:9582303 NCBI chr 3:52,253,413...52,826,508
Ensembl chr 3:52,253,618...52,825,313 		JBrowse link
G B3galt2 Beta-1,3-galactosyltransferase 2 involved_in ISO (PMID:9582303) RGD PMID:9582303 NCBI chr13:55,389,406...55,398,419
Ensembl chr13:55,389,406...55,398,419 		JBrowse link
G B4galt3 beta-1,4-galactosyltransferase 3 involved_in IBA
IEA
ISO		 PMID:21873635
GO_REF:0000107
(PMID:9405390)		 Ensembl
RGD		 PMID:9405390 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr13:83,691,378...83,697,448
Ensembl chr13:83,691,446...83,697,448 		JBrowse link
G Fa2h fatty acid 2-hydroxylase involved_in ISS
ISO
IMP
IEA		 GO_REF:0000024
(MGI:3696647|PMID:15658937), (MGI:3826747|PMID:18815260)
PMID:17901466
GO_REF:0000041		 UniProt
RGD		 PMID:15658937 PMID:18815260 PMID:17901466 GO_REF:0000024 GO_REF:0000041 MGI:3696647 MGI:3826747, RGD:13825191 NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153 		JBrowse link
G Gal3st1 galactose-3-O-sulfotransferase 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:1355015|PMID:10727929)		 RGD PMID:10727929 PMID:21873635 MGI:1355015, RGD:13792537 NCBI chr14:78,868,049...78,886,402
Ensembl chr14:78,870,793...78,886,388 		JBrowse link
G Ugt8 UDP glycosyltransferase 8 involved_in IDA
IBA
IEA		 PMID:8713090
PMID:21873635
GO_REF:0000041		 UniProt PMID:8713090 PMID:21873635 GO_REF:0000041, RGD:39458006, RGD:13792537 NCBI chr 2:214,264,483...214,332,769
Ensembl chr 2:214,264,483...214,332,660 		JBrowse link
ganglioside biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3galt4 Beta-1,3-galactosyltransferase 4 involved_in ISO
IEA		 (PMID:9582303)
GO_REF:0000107		 RGD
Ensembl		 PMID:9582303 GO_REF:0000107 NCBI chr20:4,936,089...4,937,664
Ensembl chr20:4,931,768...4,938,315 		JBrowse link
G B4galnt1 beta-1,4-N-acetyl-galactosaminyl transferase 1 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO
IDA
ISS		 PMID:21873635
GO_REF:0000107
(MGI:83232|PMID:8855236)
MGI:2158349|MGI:96074 (MGI:1331265|PMID:10021458)
PMID:3140234
(PMID:1601877), (PMID:7487055), (PMID:7890749)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:1601877 PMID:7487055 PMID:7890749 PMID:8855236 PMID:10021458 More... GO_REF:0000024 GO_REF:0000107 MGI:1331265 MGI:83232, RGD:13792537, RGD:21201261 NCBI chr 7:62,988,429...62,996,190
Ensembl chr 7:62,988,930...62,996,190 		JBrowse link
G Rps18 ribosomal protein S18 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:4,931,427...4,935,538
Ensembl chr10:101,204,500...101,205,146
Ensembl chr20:101,204,500...101,205,146 		JBrowse link
G St6galnac3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:242,129,755...242,645,120
Ensembl chr 2:242,129,763...242,645,133 		JBrowse link
G St6galnac4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:15,872,230...15,885,250
Ensembl chr 3:15,872,532...15,885,243 		JBrowse link
G St6galnac5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:241,741,933...241,911,214
Ensembl chr 2:241,742,688...241,911,208 		JBrowse link
G St6galnac6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:1354410|PMID:10702226)
PMID:21873635		 RGD PMID:10702226 PMID:21873635 MGI:1354410, RGD:13792537 NCBI chr 3:15,894,275...15,907,502
Ensembl chr 3:15,885,968...15,907,496 		JBrowse link
G St8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 involved_in ISO (PMID:10766765) RGD PMID:10766765 NCBI chr 1:127,762,573...127,838,017
Ensembl chr 1:127,762,573...127,838,091 		JBrowse link
G St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 involved_in ISO (PMID:10766765) RGD PMID:10766765 NCBI chr18:57,754,349...57,760,839
Ensembl chr18:57,754,347...57,760,839 		JBrowse link
G St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 involved_in ISO (PMID:10766765) RGD PMID:10766765 NCBI chr 9:95,990,131...96,084,661
Ensembl chr 9:95,993,503...96,084,653 		JBrowse link
G St8sia6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 involved_in ISO (MGI:2182536|PMID:11980897) RGD PMID:11980897 MGI:2182536 NCBI chr17:76,740,755...76,884,178
Ensembl chr17:76,745,224...76,884,299 		JBrowse link
ganglioside biosynthetic process via lactosylceramide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt5 beta-1,4-galactosyltransferase 5 involved_in ISO (MGI:6196231|PMID:30114188) RGD PMID:30114188 MGI:6196231 NCBI chr 3:156,018,056...156,033,983
Ensembl chr 3:156,018,053...156,070,074 		JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6196231|PMID:30114188)		 UniProt
RGD		 PMID:30114188 GO_REF:0000024 MGI:6196231 NCBI chr18:11,958,382...12,015,247
Ensembl chr18:11,958,390...12,015,247 		JBrowse link
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 involved_in ISO
IBA		 (PMID:8027041)
PMID:21873635
(MGI:65558|PMID:8144500)		 RGD PMID:8027041 PMID:8144500 PMID:21873635 MGI:65558, RGD:13792537 NCBI chr 7:98,845,270...98,913,409
Ensembl chr 7:98,845,270...98,913,236 		JBrowse link
G St3gal2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 involved_in IDA
IBA
IEA
ISO		 PMID:8144500
PMID:21873635
GO_REF:0000107
(MGI:6467685|PMID:22735313), (MGI:65558|PMID:8144500)
(PMID:8920913)		 Ensembl
RGD		 PMID:8144500 PMID:8920913 PMID:22735313 PMID:8144500 PMID:21873635 GO_REF:0000107 MGI:6467685 MGI:65558, RGD:68307, RGD:13792537 NCBI chr19:38,888,851...38,939,874
Ensembl chr19:38,923,999...38,939,869 		JBrowse link
G St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6467685|PMID:22735313)		 Ensembl
RGD		 PMID:22735313 GO_REF:0000107 MGI:6467685 NCBI chr 5:131,470,348...131,670,794
Ensembl chr 5:131,470,348...131,670,810 		JBrowse link
globoside biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A4galt alpha 1,4-galactosyltransferase (P blood group) acts_upstream_of_or_within ISO MGI:3624807|MGI:5445373 (MGI:3623723|PMID:16476743), (MGI:5445364|PMID:22875802) RGD PMID:16476743 PMID:22875802 MGI:3623723 MGI:5445364 NCBI chr 7:114,368,525...114,392,872
Ensembl chr 7:114,368,276...114,396,071 		JBrowse link
globoside biosynthetic process via lactosylceramide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G St3gal2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 involved_in ISO
IEA
ISS		 (PMID:12716912)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:12716912 GO_REF:0000024 GO_REF:0000107 NCBI chr19:38,888,851...38,939,874
Ensembl chr19:38,923,999...38,939,869 		JBrowse link
glucosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fa2h fatty acid 2-hydroxylase involved_in ISS
ISO		 GO_REF:0000024
(MGI:5285470|PMID:21628453)		 UniProt
RGD		 PMID:21628453 GO_REF:0000024 MGI:5285470 NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153 		JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase involved_in IBA
ISO
ISS		 PMID:21873635
(MGI:2180222|PMID:10430909), (MGI:3603060|PMID:16109770), (MGI:5448789|PMID:22851168), (MGI:5510915|PMID:23748427)
GO_REF:0000024
(PMID:8643456)		 RGD
UniProt		 PMID:8643456 PMID:10430909 PMID:16109770 PMID:22851168 PMID:23748427 More... GO_REF:0000024 MGI:2180222 MGI:3603060 MGI:5448789 MGI:5510915, RGD:13792537 NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393 		JBrowse link
glycosphingolipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A3galt2 alpha 1,3-galactosyltransferase 2 acts_upstream_of_or_within
involved_in		 IDA
ISO		 PMID:10854427
MGI:1347344|MGI:3512453 (MGI:5445364|PMID:22875802)
PMID:12626403		 RGD PMID:22875802 PMID:10854427 PMID:10854427 PMID:12626403 MGI:5445364, RGD:1299594, RGD:1299594, RGD:632674 NCBI chr 5:141,101,329...141,113,760
Ensembl chr 5:141,107,983...141,115,641 		JBrowse link
G B4galnt1 beta-1,4-N-acetyl-galactosaminyl transferase 1 involved_in IDA PMID:1606358 UniProt PMID:1606358 RGD:21201272 NCBI chr 7:62,988,429...62,996,190
Ensembl chr 7:62,988,930...62,996,190 		JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:9593693 PMID:21873635 RGD:70807, RGD:13792537 NCBI chr18:11,958,382...12,015,247
Ensembl chr18:11,958,390...12,015,247 		JBrowse link
G Fut4 fucosyltransferase 4 involved_in ISO
ISS		 (PMID:29593094)
GO_REF:0000024		 RGD
UniProt		 PMID:29593094 GO_REF:0000024 NCBI chr 8:11,586,721...11,590,682
Ensembl chr 8:11,586,721...11,590,682 		JBrowse link
G Fut4-ps1 fucosyltransferase 4, pseudogene 1 involved_in ISO (PMID:29593094) RGD PMID:29593094 NCBI chr 9:1,569,605...1,572,022 JBrowse link
G Fut9 fucosyltransferase 9 involved_in ISO
ISS		 (PMID:29593094)
GO_REF:0000024		 RGD
UniProt		 PMID:29593094 GO_REF:0000024 NCBI chr 5:39,351,815...39,565,256
Ensembl chr 5:39,351,819...39,565,130 		JBrowse link
G St6galnac5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 involved_in ISO (MGI:1346847|PMID:10521438) RGD PMID:10521438 MGI:1346847 NCBI chr 2:241,741,933...241,911,214
Ensembl chr 2:241,742,688...241,911,208 		JBrowse link
G St8sia5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 involved_in IDA PMID:1606358 UniProt PMID:1606358 RGD:21201272 NCBI chr18:70,736,395...70,802,537
Ensembl chr18:70,736,602...70,797,789 		JBrowse link
G Tm9sf2 transmembrane 9 superfamily member 2 involved_in ISO (PMID:30660999) RGD PMID:30660999 NCBI chr15:99,201,556...99,254,054
Ensembl chr15:99,201,489...99,254,049 		JBrowse link
G Ugt8 UDP glycosyltransferase 8 TAS RGD PMID:7521399 RGD:70050 NCBI chr 2:214,264,483...214,332,769
Ensembl chr 2:214,264,483...214,332,660 		JBrowse link
lactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt4 beta-1,4-galactosyltransferase 4 involved_in ISO
ISS		 (PMID:9792633)
GO_REF:0000024		 RGD
UniProt		 PMID:9792633 GO_REF:0000024 NCBI chr11:61,995,807...62,021,751
Ensembl chr11:61,995,814...62,021,671 		JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in ISO (PMID:10320813) RGD PMID:10320813 NCBI chr18:11,958,382...12,015,247
Ensembl chr18:11,958,390...12,015,247 		JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of_or_within ISO (PMID:25691431) RGD PMID:25691431 NCBI chr 9:48,243,365...48,253,316
Ensembl chr 9:48,237,572...48,253,211 		JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 acts_upstream_of_or_within ISO (PMID:25691431) RGD PMID:25691431 NCBI chr 7:1,247,869...1,250,999
Ensembl chr 7:1,246,479...1,250,907 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:25691431)
(MGI:5638294|PMID:25691431)		 Ensembl
RGD		 PMID:25691431 GO_REF:0000107 MGI:5638294 NCBI chr10:83,590,052...83,596,035
Ensembl chr10:83,590,071...83,598,620 		JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:6294167|PMID:16118219)
(PMID:16118219)		 UniProt
Ensembl
RGD		 PMID:16118219 GO_REF:0000024 GO_REF:0000107 MGI:6294167 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240 		JBrowse link
negative regulation of sphingolipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 involved_in ISO
IEA
IMP		 (PMID:24201375)
GO_REF:0000107		 RGD
Ensembl		 PMID:24201375 PMID:24201375 GO_REF:0000107, RGD:14697729 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537 		JBrowse link
G Atg7 autophagy related 7 acts_upstream_of_or_within ISO MGI:2176073|MGI:3587769 (MGI:5613260|PMID:25332431) RGD PMID:25332431 MGI:5613260 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
omega-hydroxyceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnpla1 patatin-like phospholipase domain containing 1 involved_in ISO (PMID:28248318)
(MGI:5888934|PMID:28248300)		 RGD PMID:28248300 PMID:28248318 MGI:5888934 NCBI chr20:6,917,993...6,952,157
Ensembl chr20:6,917,931...6,952,375 		JBrowse link
phytosphingosine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer3 alkaline ceramidase 3 involved_in IBA
ISO		 PMID:21873635
(PMID:11356846), (PMID:20068046)		 RGD PMID:11356846 PMID:20068046 PMID:21873635 RGD:13792537 NCBI chr 1:152,504,180...152,606,596
Ensembl chr 1:152,504,186...152,606,591 		JBrowse link
positive regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn1 cellular communication network factor 1 acts_upstream_of_or_within ISO (MGI:3849354|PMID:19364818) RGD PMID:19364818 MGI:3849354 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4947032|PMID:21177474)		 UniProt
RGD		 PMID:21177474 GO_REF:0000024 MGI:4947032 NCBI chr10:104,242,169...104,247,185
Ensembl chr10:104,242,223...104,246,589 		JBrowse link
G Pla2g6 phospholipase A2 group VI involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:18936091 PMID:21873635 RGD:6482750, RGD:13792537 NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114 		JBrowse link
G Prkcd protein kinase C, delta involved_in ISO
IEA		 (PMID:19279011)
GO_REF:0000107		 RGD
Ensembl		 PMID:19279011 GO_REF:0000107 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Sirt3 sirtuin 3 involved_in ISO (MGI:5755322|PMID:26620563) RGD PMID:26620563 MGI:5755322 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 IMP RGD PMID:20096352 RGD:10041064 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (PMID:16118219)
(MGI:6294167|PMID:16118219)		 RGD PMID:16118219 MGI:6294167 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391 		JBrowse link
regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENSRNOG00000068509 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 Ensembl chr17:11,942,344...11,942,538 JBrowse link
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of ISO MGI:1913862 (MGI:6393026|PMID:31880535) RGD PMID:31880535 MGI:6393026 NCBI chr 9:48,243,365...48,253,316
Ensembl chr 9:48,237,572...48,253,211 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of ISO MGI:2137691|MGI:2181669|MGI:6382064 (MGI:6393026|PMID:31880535) RGD PMID:31880535 MGI:6393026 NCBI chr10:83,590,052...83,596,035
Ensembl chr10:83,590,071...83,598,620 		JBrowse link
G Prkcd protein kinase C, delta involved_in ISO
ISS		 (PMID:17303575)
GO_REF:0000024		 RGD
UniProt		 PMID:17303575 GO_REF:0000024 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Samd8 sterile alpha motif domain containing 8 involved_in ISO (PMID:19506037) RGD PMID:19506037 NCBI chr15:2,512,104...2,562,368
Ensembl chr15:2,512,105...2,515,379
Ensembl chr15:2,512,105...2,515,379 		JBrowse link
regulation of sphingolipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of ISO MGI:1913862 (MGI:6393026|PMID:31880535) RGD PMID:31880535 MGI:6393026 NCBI chr 9:48,243,365...48,253,316
Ensembl chr 9:48,237,572...48,253,211 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of ISO MGI:2137691|MGI:2181669|MGI:2445707|MGI:6343506|MGI:6382064 (MGI:5926671|PMID:28275141), (MGI:6393026|PMID:31880535) RGD PMID:28275141 PMID:31880535 MGI:5926671 MGI:6393026 NCBI chr10:83,590,052...83,596,035
Ensembl chr10:83,590,071...83,598,620 		JBrowse link
sphinganine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 acts_upstream_of_or_within ISO MGI:3815115 (MGI:3846467|PMID:19416652) RGD PMID:19416652 MGI:3846467 NCBI chr17:11,877,249...11,916,295
Ensembl chr17:11,877,249...11,916,295 		JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1098386|PMID:9363775)
GO_REF:0000107		 RGD
Ensembl		 PMID:9363775 GO_REF:0000107 MGI:1098386 NCBI chr 6:106,948,682...107,031,532
Ensembl chr 6:106,950,949...107,031,542 		JBrowse link
sphinganine-1-phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sphk2 sphingosine kinase 2 involved_in ISO
IBA		 (PMID:10751414), (PMID:19729656)
PMID:21873635
(MGI:1860308|PMID:10751414)		 RGD PMID:10751414 PMID:19729656 PMID:21873635 MGI:1860308, RGD:13792537 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391 		JBrowse link
sphingoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sptlc3 serine palmitoyltransferase, long chain base subunit 3 acts_upstream_of_or_within ISO (PMID:19648650) RGD PMID:19648650 NCBI chr 3:126,847,878...126,978,010
Ensembl chr 3:126,847,878...126,978,010 		JBrowse link
sphingomyelin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca8 ATP binding cassette subfamily A member 8 involved_in ISO (PMID:23560799) RGD PMID:23560799 NCBI chr10:94,917,520...94,991,199
Ensembl chr10:94,917,520...94,990,988 		JBrowse link
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of ISO MGI:1913862 (MGI:6393026|PMID:31880535) RGD PMID:31880535 MGI:6393026 NCBI chr 9:48,243,365...48,253,316
Ensembl chr 9:48,237,572...48,253,211 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of
involved_in		 ISO
IEA		 MGI:2137691|MGI:2181669|MGI:6382064 (MGI:6393026|PMID:31880535)
GO_REF:0000107		 RGD
Ensembl		 PMID:31880535 GO_REF:0000107 MGI:6393026 NCBI chr10:83,590,052...83,596,035
Ensembl chr10:83,590,071...83,598,620 		JBrowse link
G Osbp oxysterol binding protein involved_in ISO (PMID:12023275) RGD PMID:12023275 NCBI chr 1:208,888,697...208,918,511
Ensembl chr 1:208,887,895...208,918,506 		JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase acts_upstream_of_or_within ISO (MGI:5707904|PMID:25667419) RGD PMID:25667419 MGI:5707904 NCBI chr10:44,775,910...44,849,990
Ensembl chr10:44,775,911...44,850,013 		JBrowse link
G Sgms1 sphingomyelin synthase 1 involved_in IBA
ISO
ISS		 PMID:21873635
(MGI:6221394|PMID:27892528)
GO_REF:0000024
(PMID:14685263), (PMID:14976195), (PMID:17982138)		 RGD
HGNC-UCL		 PMID:14685263 PMID:14976195 PMID:17982138 PMID:27892528 PMID:21873635 GO_REF:0000024 MGI:6221394, RGD:13792537 NCBI chr 1:229,996,673...230,259,591
Ensembl chr 1:229,998,119...230,259,603 		JBrowse link
G Sgms2 sphingomyelin synthase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
(MGI:6221394|PMID:27892528)
(MGI:5707904|PMID:25667419)
(PMID:14685263), (PMID:17982138)
PMID:21873635		 Ensembl
RGD		 PMID:14685263 PMID:17982138 PMID:25667419 PMID:27892528 PMID:21873635 GO_REF:0000107 MGI:5707904 MGI:6221394, RGD:13792537 NCBI chr 2:219,889,809...219,967,704
Ensembl chr 2:219,893,572...219,967,546 		JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 involved_in
acts_upstream_of_or_within		 ISO (MGI:5749304|PMID:26301690)
MGI:3815115 (MGI:3814228|PMID:16216550)		 RGD PMID:16216550 PMID:26301690 MGI:3814228 MGI:5749304 NCBI chr17:11,877,249...11,916,295
Ensembl chr17:11,877,249...11,916,295 		JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3815117 (MGI:3814228|PMID:16216550)
GO_REF:0000107		 RGD
Ensembl		 PMID:16216550 GO_REF:0000107 MGI:3814228 NCBI chr 6:106,948,682...107,031,532
Ensembl chr 6:106,950,949...107,031,542 		JBrowse link
G Vapa VAMP associated protein A involved_in ISO (PMID:12023275) RGD PMID:12023275 NCBI chr 9:105,177,904...105,208,400
Ensembl chr 9:105,177,907...105,207,847 		JBrowse link
sphingosine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of_positive_effect
involved_in		 ISO
IEA		 (PMID:26510981)
GO_REF:0000107		 RGD
Ensembl		 PMID:26510981 GO_REF:0000107 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537 		JBrowse link
G Acer1 alkaline ceramidase 1 involved_in ISO
IBA		 (PMID:17713573), (PMID:20207939), (PMID:20628055)
PMID:21873635
(MGI:5800647|PMID:27126290), (MGI:6107252|PMID:29056331)		 RGD PMID:17713573 PMID:20207939 PMID:20628055 PMID:27126290 PMID:29056331 More... MGI:5800647 MGI:6107252, RGD:13792537 NCBI chr 9:1,794,340...1,824,432
Ensembl chr 9:1,793,139...1,824,434 		JBrowse link
G Acer2 alkaline ceramidase 2 involved_in ISO
IBA		 (PMID:16940153), (PMID:20089856), (PMID:20207939), (PMID:20628055)
PMID:21873635
(MGI:6116621|PMID:29401619)		 RGD PMID:16940153 PMID:20089856 PMID:20207939 PMID:20628055 PMID:29401619 More... MGI:6116621, RGD:13792537 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614 		JBrowse link
G Acer3 alkaline ceramidase 3 involved_in ISO (PMID:20068046), (PMID:20207939), (PMID:26792856)
(MGI:5749603|PMID:26474409)		 RGD PMID:20068046 PMID:20207939 PMID:26474409 PMID:26792856 MGI:5749603 NCBI chr 1:152,504,180...152,606,596
Ensembl chr 1:152,504,186...152,606,591 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:1267186|PMID:9653654)
(PMID:10610716), (PMID:12815059)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:9653654 PMID:10610716 PMID:12815059 GO_REF:0000024 GO_REF:0000107 MGI:1267186 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233 		JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in IDA
ISO
IBA		 PMID:10488143
PMID:15123644
(MGI:3608219|PMID:16126722), (MGI:3640407|PMID:16380386), (MGI:6275120|PMID:10652340)
PMID:15217782
PMID:21873635
(PMID:30154232)		 RGD PMID:10652340 PMID:16126722 PMID:16380386 PMID:30154232 PMID:10488143 More... MGI:3608219 MGI:3640407 MGI:6275120, RGD:13838800, RGD:13838793, RGD:13838794, RGD:13792537 NCBI chr 1:229,865,662...229,973,253
Ensembl chr 1:229,865,662...229,939,162 		JBrowse link
G ENSRNOG00000069695 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 Ensembl chr14:25,729,638...25,730,194 JBrowse link
G Gba1 glucosylceramidase beta 1 involved_in ISO (PMID:19279011) RGD PMID:19279011 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISO
IEA
IBA		 UniProtKB:Q9NRA0 (PMID:23106337)
GO_REF:0000107
PMID:21873635		 RGD
Ensembl		 PMID:23106337 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO
IBA		 UniProtKB:Q9NYA1 (PMID:23106337)
PMID:21873635		 RGD PMID:23106337 PMID:21873635 RGD:13792537 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391 		JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:3815115 (MGI:3814228|PMID:16216550)
PMID:21873635
(PMID:19416851), (PMID:33558761)		 RGD PMID:16216550 PMID:19416851 PMID:33558761 PMID:21873635 MGI:3814228, RGD:13792537 NCBI chr17:11,877,249...11,916,295
Ensembl chr17:11,877,249...11,916,295 		JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 acts_upstream_of_or_within
involved_in		 ISO
IEA
IBA		 MGI:3815117 (MGI:3814228|PMID:16216550)
GO_REF:0000107
PMID:21873635
(PMID:19416851), (PMID:33558761)		 RGD
Ensembl		 PMID:16216550 PMID:19416851 PMID:33558761 PMID:21873635 GO_REF:0000107 MGI:3814228, RGD:13792537 NCBI chr 6:106,948,682...107,031,532
Ensembl chr 6:106,950,949...107,031,542 		JBrowse link
G Sptlc3 serine palmitoyltransferase, long chain base subunit 3 involved_in ISO
IBA		 (PMID:19416851)
PMID:21873635		 RGD PMID:19416851 PMID:21873635 RGD:13792537 NCBI chr 3:126,847,878...126,978,010
Ensembl chr 3:126,847,878...126,978,010 		JBrowse link
G Sptssa serine palmitoyltransferase, small subunit A involved_in ISO (PMID:19416851), (PMID:33558761) RGD PMID:19416851 PMID:33558761 NCBI chr 6:72,144,714...72,156,130
Ensembl chr 6:72,144,714...72,156,214 		JBrowse link
G Sptssb serine palmitoyltransferase, small subunit B involved_in ISO (PMID:19416851) RGD PMID:19416851 NCBI chr 2:154,133,728...154,162,127
Ensembl chr 2:154,133,733...154,163,120 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19574
    metabolic process 11556
      cellular metabolic process 10142
        cellular biosynthetic process 7943
          membrane lipid biosynthetic process 115
            sphingolipid biosynthetic process 100
              ceramide biosynthetic process + 71
              ceramide phosphoethanolamine biosynthetic process 2
              glycosphingolipid biosynthetic process + 31
              negative regulation of sphingolipid biosynthetic process + 6
              positive regulation of sphingolipid biosynthetic process + 7
              regulation of sphingolipid biosynthetic process + 15
              sphinganine-1-phosphate biosynthetic process 1
              sphingoid biosynthetic process + 15
              sphingolipid biosynthesis involved in endoplasmic reticulum membrane organization 0
              sphingomyelin biosynthetic process 10
Path 2
Term Annotations click to browse term
  biological_process 19574
    metabolic process 11556
      primary metabolic process 9996
        lipid metabolic process 1406
          cellular lipid metabolic process 1035
            membrane lipid metabolic process 176
              membrane lipid biosynthetic process 115
                sphingolipid biosynthetic process 100
                  ceramide biosynthetic process + 71
                  ceramide phosphoethanolamine biosynthetic process 2
                  glycosphingolipid biosynthetic process + 31
                  negative regulation of sphingolipid biosynthetic process + 6
                  positive regulation of sphingolipid biosynthetic process + 7
                  regulation of sphingolipid biosynthetic process + 15
                  sphinganine-1-phosphate biosynthetic process 1
                  sphingoid biosynthetic process + 15
                  sphingolipid biosynthesis involved in endoplasmic reticulum membrane organization 0
                  sphingomyelin biosynthetic process 10
paths to the root