ORMDL1 (ORMDL sphingolipid biosynthesis regulator 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: ORMDL1 (ORMDL sphingolipid biosynthesis regulator 1) Canis lupus familiaris
Analyze
Symbol: ORMDL1
Name: ORMDL sphingolipid biosynthesis regulator 1
RGD ID: 12327942
Description: INVOLVED IN motor behavior (ortholog); myelination (ortholog); negative regulation of ceramide biosynthetic process (ortholog); ASSOCIATED WITH genetic disease (ortholog); immunodeficiency 31B (ortholog); Lynch syndrome (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ORM1-like 1; ORM1-like protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.137509,592 - 521,511 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl37511,149 - 522,865 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha371,483,024 - 1,494,763 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.037403,411 - 415,148 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl37400,745 - 415,141 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.137413,833 - 425,569 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.037382,316 - 394,032 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.037410,296 - 422,040 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ORMDL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.137509,592 - 521,511 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl37511,149 - 522,865 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha371,483,024 - 1,494,763 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.037403,411 - 415,148 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl37400,745 - 415,141 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.137413,833 - 425,569 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.037382,316 - 394,032 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.037410,296 - 422,040 (-)NCBIUU_Cfam_GSD_1.0
ORMDL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382189,763,859 - 189,784,339 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2189,770,267 - 189,784,364 (-)EnsemblGRCh38hg38GRCh38
GRCh372190,628,585 - 190,649,065 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362190,343,295 - 190,355,677 (-)NCBINCBI36Build 36hg18NCBI36
Build 342190,460,555 - 190,472,938NCBI
Celera2184,229,906 - 184,244,025 (-)NCBICelera
Cytogenetic Map2q32.2NCBI
HuRef2182,494,629 - 182,508,748 (-)NCBIHuRef
CHM1_12190,640,856 - 190,654,980 (-)NCBICHM1_1
T2T-CHM13v2.02190,253,126 - 190,273,622 (-)NCBIT2T-CHM13v2.0
Ormdl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39153,336,254 - 53,349,404 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl153,336,254 - 53,349,468 (+)EnsemblGRCm39 Ensembl
GRCm38153,297,095 - 53,310,245 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl153,297,095 - 53,310,309 (+)EnsemblGRCm38mm10GRCm38
MGSCv37153,353,939 - 53,367,089 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36153,241,658 - 53,254,783 (+)NCBIMGSCv36mm8
Celera153,836,500 - 53,849,637 (+)NCBICelera
Cytogenetic Map1C1.1NCBI
cM Map126.99NCBI
Ormdl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8955,735,081 - 55,745,287 (-)NCBIGRCr8
mRatBN7.2948,243,365 - 48,253,316 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl948,237,572 - 48,253,211 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx956,779,537 - 56,789,480 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0961,902,356 - 61,912,299 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0960,198,344 - 60,208,289 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0953,110,628 - 53,120,454 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl953,111,371 - 53,118,613 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0952,775,064 - 52,784,570 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4945,192,469 - 45,203,142 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera945,909,024 - 45,919,336 (-)NCBICelera
Cytogenetic Map9q22NCBI
Ormdl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554039,100,516 - 9,113,223 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554039,100,516 - 9,113,230 (+)NCBIChiLan1.0ChiLan1.0
ORMDL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21392,462,515 - 92,476,701 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B92,477,503 - 92,491,587 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B77,076,432 - 77,090,531 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B194,997,037 - 195,010,516 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B194,996,437 - 195,009,102 (-)Ensemblpanpan1.1panPan2
Ormdl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303148,628,622 - 148,641,164 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365068,196,784 - 8,210,584 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365068,197,116 - 8,208,712 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ORMDL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1594,359,358 - 94,377,303 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11594,359,784 - 94,377,331 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215105,397,162 - 105,414,708 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ORMDL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11075,291,320 - 75,305,412 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1075,287,780 - 75,305,001 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040124,175,553 - 124,189,636 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in ORMDL1
75 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 3 21 5 4 5 6 12 8 10 2
Low 2 5 1 1 2 1 6 4
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022414970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022414971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038447378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038447379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038447380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038521442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038521443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038521444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038585146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038585147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038585148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038649556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038649557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038649558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_843173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005308117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005318551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005351076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005385026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005418752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSCAFT00000014934   ⟹   ENSCAFP00000013821
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl37511,149 - 521,016 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000089771   ⟹   ENSCAFP00000047201
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl37511,149 - 522,865 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845042961   ⟹   ENSCAFP00845033678
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl37400,745 - 415,141 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845043011   ⟹   ENSCAFP00845033722
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl37408,910 - 414,667 (-)Ensembl
RefSeq Acc Id: XM_022414970   ⟹   XP_022270678
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.137509,711 - 521,036 (-)NCBI
Dog10K_Boxer_Tasha371,483,024 - 1,494,359 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022414971   ⟹   XP_022270679
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.137509,592 - 520,122 (-)NCBI
Dog10K_Boxer_Tasha371,483,024 - 1,493,397 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038447378   ⟹   XP_038303306
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.037403,411 - 415,148 (-)NCBI
RefSeq Acc Id: XM_038447379   ⟹   XP_038303307
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.037403,411 - 414,744 (-)NCBI
RefSeq Acc Id: XM_038447380   ⟹   XP_038303308
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.037403,411 - 413,782 (-)NCBI
RefSeq Acc Id: XM_038521442   ⟹   XP_038377370
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.137413,833 - 425,569 (-)NCBI
RefSeq Acc Id: XM_038521443   ⟹   XP_038377371
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.137413,833 - 425,165 (-)NCBI
RefSeq Acc Id: XM_038521444   ⟹   XP_038377372
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.137413,833 - 424,205 (-)NCBI
RefSeq Acc Id: XM_038585146   ⟹   XP_038441074
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.037410,296 - 422,040 (-)NCBI
RefSeq Acc Id: XM_038585147   ⟹   XP_038441075
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.037410,296 - 421,636 (-)NCBI
RefSeq Acc Id: XM_038585148   ⟹   XP_038441076
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.037410,296 - 420,675 (-)NCBI
RefSeq Acc Id: XM_038649556   ⟹   XP_038505484
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.037382,316 - 394,032 (-)NCBI
RefSeq Acc Id: XM_038649557   ⟹   XP_038505485
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.037382,316 - 393,653 (-)NCBI
RefSeq Acc Id: XM_038649558   ⟹   XP_038505486
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.037382,316 - 392,692 (-)NCBI
RefSeq Acc Id: XM_843173   ⟹   XP_848266
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.137509,592 - 521,511 (-)NCBI
Dog10K_Boxer_Tasha371,483,024 - 1,494,763 (-)NCBI
Sequence:
RefSeq Acc Id: XR_005308117
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.037404,828 - 415,148 (-)NCBI
RefSeq Acc Id: XR_005318551
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha371,484,441 - 1,494,763 (-)NCBI
RefSeq Acc Id: XR_005351076
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.137415,250 - 425,569 (-)NCBI
RefSeq Acc Id: XR_005385026
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.037411,713 - 422,040 (-)NCBI
RefSeq Acc Id: XR_005418752
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.037383,733 - 394,032 (-)NCBI
RefSeq Acc Id: XP_848266   ⟸   XM_843173
- UniProtKB: A0A8C0K0F3 (UniProtKB/TrEMBL),   A0A8C0NEH2 (UniProtKB/TrEMBL),   A0A8I3PQ53 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022270679   ⟸   XM_022414971
- UniProtKB: A0A8C0K0F3 (UniProtKB/TrEMBL),   A0A8C0NEH2 (UniProtKB/TrEMBL),   A0A8I3PQ53 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022270678   ⟸   XM_022414970
- UniProtKB: A0A8C0K0F3 (UniProtKB/TrEMBL),   A0A8C0NEH2 (UniProtKB/TrEMBL),   A0A8I3PQ53 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000013821   ⟸   ENSCAFT00000014934
RefSeq Acc Id: ENSCAFP00000047201   ⟸   ENSCAFT00000089771
RefSeq Acc Id: XP_038377370   ⟸   XM_038521442
RefSeq Acc Id: XP_038377371   ⟸   XM_038521443
RefSeq Acc Id: XP_038377372   ⟸   XM_038521444
RefSeq Acc Id: XP_038505484   ⟸   XM_038649556
RefSeq Acc Id: XP_038505485   ⟸   XM_038649557
RefSeq Acc Id: XP_038505486   ⟸   XM_038649558
RefSeq Acc Id: XP_038303306   ⟸   XM_038447378
- UniProtKB: A0A8C0K0F3 (UniProtKB/TrEMBL),   A0A8C0NEH2 (UniProtKB/TrEMBL),   A0A8I3PQ53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038303307   ⟸   XM_038447379
- UniProtKB: A0A8C0K0F3 (UniProtKB/TrEMBL),   A0A8C0NEH2 (UniProtKB/TrEMBL),   A0A8I3PQ53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038303308   ⟸   XM_038447380
- UniProtKB: A0A8C0K0F3 (UniProtKB/TrEMBL),   A0A8C0NEH2 (UniProtKB/TrEMBL),   A0A8I3PQ53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038441074   ⟸   XM_038585146
- UniProtKB: A0A8C0K0F3 (UniProtKB/TrEMBL),   A0A8C0NEH2 (UniProtKB/TrEMBL),   A0A8I3PQ53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038441075   ⟸   XM_038585147
- UniProtKB: A0A8C0K0F3 (UniProtKB/TrEMBL),   A0A8C0NEH2 (UniProtKB/TrEMBL),   A0A8I3PQ53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038441076   ⟸   XM_038585148
- UniProtKB: A0A8C0K0F3 (UniProtKB/TrEMBL),   A0A8C0NEH2 (UniProtKB/TrEMBL),   A0A8I3PQ53 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845033722   ⟸   ENSCAFT00845043011
RefSeq Acc Id: ENSCAFP00845033678   ⟸   ENSCAFT00845042961


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000009388 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030015836 UniProtKB/TrEMBL
  ENSCAFG00040013116 UniProtKB/TrEMBL
  ENSCAFG00845024320 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000014934.4 UniProtKB/TrEMBL
  ENSCAFT00000101446.1 UniProtKB/TrEMBL
  ENSCAFT00030029157.1 UniProtKB/TrEMBL
  ENSCAFT00040024246.1 UniProtKB/TrEMBL
  ENSCAFT00845042961 ENTREZGENE
  ENSCAFT00845042961.1 UniProtKB/TrEMBL
  ENSCAFT00845043011.1 UniProtKB/TrEMBL
InterPro ORMDL UniProtKB/TrEMBL
NCBI Gene ORMDL1 ENTREZGENE
PANTHER PTHR12665 UniProtKB/TrEMBL
  PTHR12665:SF12 UniProtKB/TrEMBL
Pfam ORMDL UniProtKB/TrEMBL
PIRSF ORMDL UniProtKB/TrEMBL
UniProt A0A8C0K0F3 ENTREZGENE
  A0A8C0NEH2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PQ53 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PRE4_CANLF UniProtKB/TrEMBL
  A0A8P0NBI8_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:44146 ENTREZGENE