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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
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Accession:GO:1902237 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.
Synonyms:exact_synonym: positive regulation of ER stress-induced apoptosis;   positive regulation of apoptosis in response to ER stress;   positive regulation of apoptosis triggered by ER stress;   positive regulation of endoplasmic reticulum stress-induced apoptosis;   positive regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;   positive regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress;   up regulation of ER stress-induced apoptosis;   up regulation of apoptosis in response to ER stress;   up regulation of apoptosis triggered by ER stress;   up regulation of endoplasmic reticulum stress-induced apoptosis;   up regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;   up regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress;   upregulation of ER stress-induced apoptosis;   upregulation of apoptosis in response to ER stress;   upregulation of apoptosis triggered by ER stress;   upregulation of endoplasmic reticulum stress-induced apoptosis;   upregulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;   upregulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress
 narrow_synonym: activation of ER stress-induced apoptosis;   activation of apoptosis in response to ER stress;   activation of apoptosis triggered by ER stress;   activation of endoplasmic reticulum stress-induced apoptosis;   activation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;   activation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress


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positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BOK BCL2 family apoptosis regulator BOK involved_in ISO (MGI:5648772|PMID:26015568)
(MGI:5796067|PMID:26949185)		 UniProt PMID:26015568 PMID:26949185 MGI:5648772 MGI:5796067 NCBI chr25:51,449,700...51,450,967 JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO (PMID:22240901) MGI PMID:22240901 NCBI chr17:37,886,397...37,950,671
Ensembl chr17:37,886,601...37,949,812 		JBrowse link
G NCK1 NCK adaptor protein 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr23:33,297,660...33,374,025
Ensembl chr23:33,297,756...33,372,534 		JBrowse link
G NCK2 NCK adaptor protein 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:37,584,351...37,734,388
Ensembl chr10:37,585,565...37,732,994 		JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:78,160,564...78,252,382
Ensembl chr 7:78,160,589...78,252,719 		JBrowse link
G RNF183 ring finger protein 183 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:67,660,593...67,669,633 JBrowse link
G SERINC3 serine incorporator 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12486168) Ensembl
MGI		 PMID:12486168 GO_REF:0000107 NCBI chr24:31,961,828...31,982,265
Ensembl chr24:31,963,840...31,982,165 		JBrowse link
G SIRT1 sirtuin 1 involved_in ISO (MGI:5607229|PMID:20955178) UniProt PMID:20955178 MGI:5607229 NCBI chr 4:19,188,616...19,220,031
Ensembl chr 4:19,188,675...19,218,279 		JBrowse link
G SPOP speckle type BTB/POZ protein acts_upstream_of_or_within ISO (PMID:20811152) MGI PMID:20811152 NCBI chr 9:25,685,723...25,752,953
Ensembl chr 9:25,686,439...25,752,900 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17307
    positive regulation of biological process 6436
      positive regulation of response to stimulus 2381
        positive regulation of response to endoplasmic reticulum stress 36
          positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 9
Path 2
Term Annotations click to browse term
  biological_process 17307
    biological regulation 12007
      regulation of biological process 11676
        regulation of cellular process 11187
          signal transduction 6098
            apoptotic signaling pathway 655
              regulation of apoptotic signaling pathway 441
                positive regulation of apoptotic signaling pathway 173
                  positive regulation of intrinsic apoptotic signaling pathway 78
                    positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 9
paths to the root