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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of apoptotic signaling pathway
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Accession:GO:2001235 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway.
Synonyms:exact_synonym: positive regulation of apoptotic signalling pathway
 never_in_taxon: NCBITaxon:4896 ! Schizosaccharomyces pombe



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positive regulation of apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07025928.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 4:51,682,224...51,682,961 JBrowse link
G Adora2a adenosine A2a receptor acts_upstream_of_or_within ISO MGI:2155985 (PMID:10845921) RGD PMID:10845921 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 acts_upstream_of_or_within ISO MGI:1889507 (PMID:16183742) RGD PMID:16183742 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Bid BH3 interacting domain death agonist acts_upstream_of_or_within ISO (PMID:8918887) RGD PMID:8918887 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bmf Bcl2 modifying factor acts_upstream_of_or_within ISO (PMID:11546872) RGD PMID:11546872 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta acts_upstream_of_or_within ISO (PMID:17367784) RGD PMID:17367784 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
JBrowse link
G Casp2 caspase 2 acts_upstream_of_or_within ISO MGI:1889507 (PMID:16183742) RGD PMID:16183742 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Casp9 caspase 9 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:1889507 (PMID:16183742)
GO_Central
RGD
PMID:16183742 GO_REF:0000033 NCBI chr 7:29,940,240...29,952,907
Ensembl chr 7:29,798,586...29,952,907
JBrowse link
G Cts7 cathepsin 7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:3,388,299...3,424,664
Ensembl chr17:3,388,299...3,393,439
JBrowse link
G Cts7l1 cathepsin 7 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:3,306,668...3,311,964
Ensembl chr17:3,307,748...3,311,679
JBrowse link
G Cts7l2 cathepsin 7 like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:3,903,602...3,907,088
Ensembl chr17:3,903,602...3,906,568
JBrowse link
G Cts8 cathepsin 8 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:3,468,710...3,480,881
Ensembl chr17:3,468,710...3,480,881
JBrowse link
G Cts8l1 cathepsin 8-like 1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr17:3,445,043...3,452,682
Ensembl chr17:3,445,043...3,452,682
JBrowse link
G Ctsc cathepsin C acts_upstream_of_or_within ISO MGI:107285 (PMID:20435891) RGD PMID:20435891 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
JBrowse link
G Ctsh cathepsin H involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:109553 (PMID:20435891)
GO_Central
RGD
PMID:20435891 GO_REF:0000033 NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824
JBrowse link
G Ctsj cathepsin J involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:3,738,729...3,743,381
Ensembl chr17:3,738,729...3,743,377
JBrowse link
G Ctsk cathepsin K involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550
JBrowse link
G Ctsl cathepsin L involved_in IEA
IBA
GO_REF:0000118
GO_REF:0000033
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
JBrowse link
G Ctsll3 cathepsin L-like 3 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr17:3,888,544...3,893,125
Ensembl chr17:3,889,811...3,892,881
JBrowse link
G Ctsm cathepsin M involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:3,236,848...3,242,265
Ensembl chr17:3,236,859...3,242,265
JBrowse link
G Ctsml1 cathepsin M like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:3,752,000...3,760,046
Ensembl chr17:3,752,000...3,760,046
JBrowse link
G Ctsq cathepsin Q involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:3,627,996...3,633,564
Ensembl chr17:3,629,082...3,633,428
JBrowse link
G Ctsql1 cathepsin Q like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:3,681,700...3,687,099
Ensembl chr17:3,681,717...3,687,099
JBrowse link
G Ctsql2 cathepsin Q-like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:3,698,973...3,704,787
Ensembl chr17:3,698,918...3,704,685
JBrowse link
G Ctsr cathepsin R involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:3,522,365...3,531,128
Ensembl chr17:3,522,365...3,531,121
JBrowse link
G Ctsrl1 cathepsin R like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:3,561,144...3,566,649
Ensembl chr17:3,561,144...3,566,639
JBrowse link
G Ctss cathepsin S involved_in IEA
IBA
GO_REF:0000118
GO_REF:0000033
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483
JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:19903888)
UniProt
Ensembl
RGD
PMID:19903888 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280
JBrowse link
G Daxx death-domain associated protein acts_upstream_of_or_within ISO MGI:104662 (PMID:10684855) RGD PMID:10684855 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
JBrowse link
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 acts_upstream_of_or_within ISO MGI:3574590 (PMID:15680327) RGD PMID:15680327 NCBI chr17:26,148,652...26,159,358
Ensembl chr17:26,148,633...26,215,720
JBrowse link
G ENSRNOG00000064602 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr13:63,590,086...63,591,393 JBrowse link
G ENSRNOG00000068437 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 6:120,369,117...120,369,706 JBrowse link
G Fas Fas cell surface death receptor involved_in ISO (PMID:11096076) RGD PMID:11096076 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Ifnb1 interferon beta 1 involved_in ISO (PMID:10918594), (PMID:11337497) RGD PMID:10918594 PMID:11337497 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523
JBrowse link
G Il19 interleukin 19 acts_upstream_of_or_within ISO (PMID:12370360) RGD PMID:12370360 NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473
JBrowse link
G Inca1 inhibitor of CDK, cyclin A1 interacting protein 1 acts_upstream_of_or_within ISO UniProtKB:Q8WYH8 (PMID:21750715) RGD PMID:21750715 NCBI chr10:55,401,989...55,414,364
Ensembl chr10:55,401,982...55,414,114
JBrowse link
G Ing5 inhibitor of growth family, member 5 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:2144284 (PMID:21750715)
GO_Central
RGD
PMID:21750715 GO_REF:0000033 NCBI chr 9:94,326,549...94,343,392
Ensembl chr 9:94,326,548...94,344,220
JBrowse link
G Inhbb inhibin subunit beta B involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:98957 (PMID:20454446)
Ensembl
RGD
PMID:20454446 GO_REF:0000107 NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832
JBrowse link
G Jak2 Janus kinase 2 acts_upstream_of_or_within ISO (PMID:15012602) RGD PMID:15012602 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Maged1 MAGE family member D1 acts_upstream_of_or_within ISO MGI:1929608 (PMID:17488777), (PMID:19268530) RGD PMID:17488777 PMID:19268530 NCBI chr  X:59,422,715...59,429,381
Ensembl chr  X:59,422,717...59,429,364
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 acts_upstream_of_or_within ISO MGI:1346862 (PMID:16458303) RGD PMID:16458303 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1346861 (PMID:16458303)
Ensembl
RGD
PMID:16458303 GO_REF:0000107 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mir449a microRNA 449a involved_in ISO (PMID:25487955) RGD PMID:25487955 NCBI chr 2:44,670,714...44,670,804
Ensembl chr 2:44,670,714...44,670,804
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor acts_upstream_of_or_within ISO MGI:2447604 (PMID:14517295) RGD PMID:14517295 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 acts_upstream_of_or_within ISO (PMID:20530871) RGD PMID:20530871 NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610
JBrowse link
G Ngfr nerve growth factor receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:10764727)
Ensembl
RGD
PMID:10764727 GO_REF:0000107 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
JBrowse link
G Nkx3-1 NK3 homeobox 1 involved_in ISO (PMID:20599703) RGD PMID:20599703 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441
JBrowse link
G Osm oncostatin M acts_upstream_of_or_within ISO (PMID:15012602) RGD PMID:15012602 NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313
JBrowse link
G Pdcd7 programmed cell death 7 acts_upstream_of_or_within ISO (PMID:10037816) RGD PMID:10037816 NCBI chr 8:65,862,606...65,877,333
Ensembl chr 8:65,862,387...65,877,333
JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within ISO MGI:1197015 (PMID:10684855) RGD PMID:10684855 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Prkcd protein kinase C, delta involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:15731106)
Ensembl
RGD
PMID:15731106 GO_REF:0000107 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Pten phosphatase and tensin homolog acts_upstream_of_or_within ISO MGI:1857937 (PMID:9778245) RGD PMID:9778245 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Rps3 ribosomal protein S3 involved_in ISO
IBA
IEA
(PMID:14988002)
GO_REF:0000033
GO_REF:0000118
RGD
GO_Central
TreeGrafter
PMID:14988002 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680
JBrowse link
G Rps3l1 ribosomal protein S3 like 1 involved_in IBA
IEA
GO_REF:0000033
GO_REF:0000118
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000118 NCBI chr 3:51,559,683...51,560,522
Ensembl chr 3:51,559,683...51,560,524
JBrowse link
G Testin testin gene involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:3,824,222...3,859,385
Ensembl chr17:3,846,899...3,859,385
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO
IEA
(PMID:18758450)
GO_REF:0000107
RGD
Ensembl
PMID:18758450 GO_REF:0000107 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Tp63 tumor protein p63 acts_upstream_of_or_within ISO (PMID:9774969) RGD PMID:9774969 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
JBrowse link
G Tp73 tumor protein p73 acts_upstream_of_or_within ISO PR:Q9QXE4-2 (PMID:16044147) RGD PMID:16044147 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128
JBrowse link
G Tpd52l1 TPD52 like 1 involved_in ISO
IBA
(PMID:14761963)
GO_REF:0000033
RGD
GO_Central
PMID:14761963 GO_REF:0000033 NCBI chr 1:26,172,038...26,290,704
Ensembl chr 1:26,172,170...26,291,109
JBrowse link
G Traf7 TNF receptor associated factor 7 involved_in ISO (PMID:15001576) RGD PMID:15001576 NCBI chr10:13,533,570...13,552,290
Ensembl chr10:13,533,570...13,552,203
JBrowse link
G Trim39 tripartite motif-containing 39 involved_in ISO
IBA
IEA
(PMID:19100260)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107
RGD
GO_Central
TreeGrafter
Ensembl
PMID:19100260 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr20:2,003,320...2,017,175
Ensembl chr20:1,983,533...2,020,117
JBrowse link
G Wnt5a Wnt family member 5A involved_in IEA
ISO
GO_REF:0000107
(MGI:5291547|PMID:21857966)
Ensembl
RGD
PMID:21857966 GO_REF:0000107 MGI:5291547 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234
JBrowse link
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
ISO
GO_REF:0000024
(MGI:5648772|PMID:26015568), (MGI:5796067|PMID:26949185)
UniProt
RGD
PMID:26015568 PMID:26949185 GO_REF:0000024 MGI:5648772 MGI:5796067 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO MGI:1913418 (PMID:22240901) RGD PMID:22240901 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO
IBA
(PMID:14676213)
GO_REF:0000033
UniProtKB:O55033 (MGI:5613475|PMID:16835242)
RGD
GO_Central
PMID:14676213 PMID:16835242 GO_REF:0000033 MGI:5613475 NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300
JBrowse link
G Nck2 NCK adaptor protein 2 involved_in ISO
IBA
UniProtKB:Q99M51 (MGI:5613475|PMID:16835242)
GO_REF:0000033
RGD
GO_Central
PMID:16835242 GO_REF:0000033 MGI:5613475 NCBI chr 9:45,713,979...45,840,330
Ensembl chr 9:45,714,883...45,840,307
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISO
IEA
(MGI:5619464|PMID:21216966)
GO_REF:0000107
RGD
Ensembl
PMID:21216966 GO_REF:0000107 MGI:5619464 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627
JBrowse link
G Rnf183 ring finger protein 183 involved_in ISO
IBA
(PMID:29507230)
GO_REF:0000033
RGD
GO_Central
PMID:29507230 GO_REF:0000033 NCBI chr 5:75,877,111...75,886,253
Ensembl chr 5:75,876,003...75,886,191
JBrowse link
G Serinc3 serine incorporator 3 acts_upstream_of_or_within ISO (PMID:12486168) RGD PMID:12486168 NCBI chr 3:152,301,882...152,321,327
Ensembl chr 3:152,301,772...152,321,808
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA
(MGI:5607229|PMID:20955178)
GO_REF:0000107
RGD
Ensembl
PMID:20955178 GO_REF:0000107 MGI:5607229 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Spop speckle type BTB/POZ protein acts_upstream_of_or_within ISO MGI:102851 (PMID:20811152) RGD PMID:20811152 NCBI chr10:80,358,121...80,438,983
Ensembl chr10:80,358,124...80,483,955
JBrowse link
positive regulation of extrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen involved_in ISO
IEA
(PMID:10406457)
GO_REF:0000107
RGD
Ensembl
PMID:10406457 GO_REF:0000107 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtr2 angiotensin II receptor, type 2 involved_in ISO (PMID:10406457) RGD PMID:10406457 NCBI chr  X:112,119,876...112,124,060
Ensembl chr  X:112,120,228...112,124,057
JBrowse link
G App amyloid beta precursor protein involved_in ISO UniProtKB:Q9EPW9|UniProtKB:Q9QUK6 (PMID:20037584) RGD PMID:20037584 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Bcl10 BCL10, immune signaling adaptor involved_in
acts_upstream_of_or_within
ISO
IBA
IEA
ISS
(PMID:11466612)
(PMID:10753917)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000024
RGD
GO_Central
TreeGrafter
UniProt
PMID:10753917 PMID:11466612 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523
JBrowse link
G Bcl2l14 Bcl2-like 14 involved_in ISO (PMID:11054413) RGD PMID:11054413 NCBI chr 4:167,217,561...167,258,723
Ensembl chr 4:167,219,871...167,258,086
JBrowse link
G Bid BH3 interacting domain death agonist involved_in ISO
IBA
IEA
(PMID:21459798)
GO_REF:0000033
GO_REF:0000104
RGD
GO_Central
UniProt
PMID:21459798 GO_REF:0000033 GO_REF:0000104 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Casp8 caspase 8 acts_upstream_of_or_within ISO MGI:1889507 (PMID:16183742) RGD PMID:16183742 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Cav1 caveolin 1 involved_in ISO
IEA
(PMID:21382479)
GO_REF:0000107
RGD
Ensembl
PMID:21382479 GO_REF:0000107 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cyld CYLD lysine 63 deubiquitinase involved_in ISO
IBA
IEA
(PMID:21525013)
GO_REF:0000033
GO_REF:0000118
RGD
GO_Central
TreeGrafter
PMID:21525013 GO_REF:0000033 GO_REF:0000118 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658
JBrowse link
G Cyld-ps1 CYLD lysine 63 deubiquitinase, pseudogene 1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 5:15,202,074...15,205,290
Ensembl chr 5:15,202,251...15,205,291
JBrowse link
G Dedd2 death effector domain containing 2 involved_in ISO (PMID:11741985) RGD PMID:11741985 NCBI chr 1:80,789,084...80,807,789
Ensembl chr 1:80,792,000...80,807,714
JBrowse link
G Fadd Fas associated via death domain involved_in
acts_upstream_of_or_within
ISO (PMID:21525013)
MGI:1336166|MGI:2154952 (PMID:22675671)
RGD PMID:21525013 PMID:22675671 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G G0s2 G0/G1switch 2 involved_in ISS
IBA
ISO
GO_REF:0000024
GO_REF:0000033
(PMID:19706769)
UniProt
GO_Central
RGD
PMID:19706769 GO_REF:0000024 GO_REF:0000033 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in IDA PMID:23907461 UniProt PMID:23907461 RGD:8553942 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
JBrowse link
G Hyal2 hyaluronidase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:19366691)
(MGI:3851310|PMID:19366691)
Ensembl
RGD
PMID:19366691 GO_REF:0000107 MGI:3851310 NCBI chr 8:108,241,895...108,246,853
Ensembl chr 8:108,243,133...108,246,850
JBrowse link
G Itm2c integral membrane protein 2C involved_in ISO (MGI:4821078|PMID:14592447) RGD PMID:14592447 MGI:4821078 NCBI chr 9:86,545,927...86,559,745
Ensembl chr 9:86,545,921...86,559,742
JBrowse link
G Ltb lymphotoxin beta involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381
JBrowse link
G Ltbr lymphotoxin beta receptor involved_in ISO (PMID:20732415) RGD PMID:20732415 NCBI chr 4:158,108,884...158,115,339
Ensembl chr 4:158,108,886...158,121,539
JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 involved_in ISO (PMID:19240112) RGD PMID:19240112 NCBI chr11:68,707,940...68,768,816
Ensembl chr11:68,707,969...68,768,816
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:15858817)
Ensembl
RGD
PMID:15858817 GO_REF:0000107 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (PMID:21803845) RGD PMID:21803845 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:1857277 (PMID:8666928) RGD PMID:8666928 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:16964285) RGD PMID:16964285 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:5000222 (PMID:19136968)
Ensembl
RGD
PMID:19136968 GO_REF:0000107 NCBI chr 3:140,789,079...140,806,017
Ensembl chr 3:140,789,080...140,806,005
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in
acts_upstream_of_or_within
ISO (PMID:21525013), (PMID:22274400)
MGI:104798 (PMID:19498109)
RGD PMID:19498109 PMID:21525013 PMID:22274400 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Runx3 RUNX family transcription factor 3 acts_upstream_of_or_within ISO MGI:2179229 (PMID:11955451) RGD PMID:11955451 NCBI chr 5:147,360,587...147,419,161
Ensembl chr 5:147,360,994...147,419,156
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 acts_upstream_of_or_within ISO MGI:3045799 (PMID:14976225) RGD PMID:14976225 NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286
JBrowse link
G Siglec1 sialic acid binding Ig like lectin 1 acts_upstream_of_or_within ISO MGI:3617694 (PMID:23408841) RGD PMID:23408841 NCBI chr 3:118,287,988...118,307,125
Ensembl chr 3:118,287,988...118,306,850
JBrowse link
G Tlr4 toll-like receptor 4 involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P05067-PRO_0000000092 (MGI:4438693|PMID:20037584)
Ensembl
RGD
PMID:20037584 GO_REF:0000107 MGI:4438693 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO UniProtKB:P05067-PRO_0000000092 (MGI:4438693|PMID:20037584) RGD PMID:20037584 MGI:4438693 NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685
JBrowse link
G Tnf tumor necrosis factor involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A involved_in ISO
IBA
(PMID:21525013)
GO_REF:0000033
RGD
GO_Central
PMID:21525013 GO_REF:0000033 NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045
JBrowse link
G Tnfsf10 TNF superfamily member 10 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:20097879), (PMID:21525171), (PMID:22266862)
(PMID:15632112)
GO_REF:0000033
RGD
GO_Central
PMID:15632112 PMID:20097879 PMID:21525171 PMID:22266862 GO_REF:0000033 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tnfsf12 TNF superfamily member 12 involved_in ISO (PMID:21525013) RGD PMID:21525013 NCBI chr10:54,403,870...54,413,213
Ensembl chr10:54,403,870...54,413,213
JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in ISO (PMID:21525013) RGD PMID:21525013 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538
JBrowse link
G Wwox WW domain-containing oxidoreductase involved_in ISO (MGI:3851310|PMID:19366691) RGD PMID:19366691 MGI:3851310 NCBI chr19:42,432,141...43,360,278
Ensembl chr19:42,432,152...43,359,391
JBrowse link
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnna1 catenin alpha 1 acts_upstream_of_or_within ISO MGI:2677796 (PMID:22411810) RGD PMID:22411810 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910
JBrowse link
G Dapk3 death-associated protein kinase 3 involved_in IMP PMID:21172653 UniProt PMID:21172653 RGD:8554227 NCBI chr 7:8,524,182...8,532,552
Ensembl chr 7:8,524,183...8,532,558
JBrowse link
G Htra2 HtrA serine peptidase 2 involved_in ISO (PMID:20125124) RGD PMID:20125124 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095
JBrowse link
G Inhba inhibin subunit beta A involved_in ISO
ISS
(PMID:8267637)
GO_REF:0000024
RGD
UniProt
PMID:8267637 GO_REF:0000024 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Jak3 Janus kinase 3 involved_in ISO (MGI:3719947|PMID:16020505) RGD PMID:16020505 MGI:3719947 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536
JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857478 (PMID:15039234)
Ensembl
RGD
PMID:15039234 GO_REF:0000107 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha acts_upstream_of_or_within ISO (PMID:12115603) RGD PMID:12115603 NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327
JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha acts_upstream_of_or_within ISO (PMID:12944463) RGD PMID:12944463 NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129
JBrowse link
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta involved_in ISO
IEA
(PMID:21172653)
GO_REF:0000107
RGD
Ensembl
PMID:21172653 GO_REF:0000107 NCBI chr 8:51,195,860...51,228,442
Ensembl chr 8:51,186,717...51,228,485
JBrowse link
G Ret ret proto-oncogene involved_in ISO (PMID:10921886) RGD PMID:10921886 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176
JBrowse link
G Srpx sushi-repeat-containing protein, X-linked acts_upstream_of_or_within ISO MGI:3706175 (PMID:17088259) RGD PMID:17088259 NCBI chr  X:12,676,984...12,751,296
Ensembl chr  X:12,566,645...12,747,882
JBrowse link
G Tgfb2 transforming growth factor, beta 2 acts_upstream_of_or_within ISO (PMID:8206089) RGD PMID:8206089 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Unc5b unc-5 netrin receptor B involved_in IMP PMID:21172653 UniProt PMID:21172653 RGD:8554227 NCBI chr20:28,697,726...28,764,474
Ensembl chr20:28,697,726...28,764,537
JBrowse link
G Wwox WW domain-containing oxidoreductase acts_upstream_of_or_within ISO (PMID:19366691) RGD PMID:19366691 NCBI chr19:42,432,141...43,360,278
Ensembl chr19:42,432,152...43,359,391
JBrowse link
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1b bone morphogenetic protein receptor type 1B acts_upstream_of_or_within ISO MGI:1927616|MGI:95484 (PMID:18363966) RGD PMID:18363966 NCBI chr 2:230,538,252...230,871,077
Ensembl chr 2:230,541,558...230,871,368
JBrowse link
G Faf1 Fas associated factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:8524870)
Ensembl
RGD
PMID:8524870 GO_REF:0000107 NCBI chr 5:124,426,032...124,790,014
Ensembl chr 5:124,426,062...124,789,977
JBrowse link
G Mal mal, T-cell differentiation protein acts_upstream_of_or_within ISO (PMID:12776198) RGD PMID:12776198 NCBI chr 3:114,864,378...114,888,136
Ensembl chr 3:114,864,378...114,888,136
JBrowse link
G Pea15 proliferation and apoptosis adaptor protein 15 acts_upstream_of_or_within ISO (PMID:10588860) RGD PMID:10588860 NCBI chr13:84,657,815...84,667,437
Ensembl chr13:84,654,870...84,667,499
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:15705586) RGD PMID:15705586 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO (PMID:8940094) RGD PMID:8940094 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in ISO
IEA
(PMID:9391078)
GO_REF:0000107
RGD
Ensembl
PMID:9391078 GO_REF:0000107 NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286
JBrowse link
G Skil SKI-like proto-oncogene acts_upstream_of_or_within ISO MGI:2387096 (PMID:10811619) RGD PMID:10811619 NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080
JBrowse link
G Stk3 serine/threonine kinase 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:104798|MGI:1928487|MGI:1929004 (PMID:20080598)
Ensembl
RGD
PMID:20080598 GO_REF:0000107 NCBI chr 7:66,053,209...66,323,292
Ensembl chr 7:66,052,345...66,323,233
JBrowse link
G Stk4 serine/threonine kinase 4 acts_upstream_of_or_within ISO MGI:104798|MGI:1928487 (PMID:20080598) RGD PMID:20080598 NCBI chr 3:152,745,958...152,827,747
Ensembl chr 3:152,745,681...152,827,744
JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:18726995) RGD PMID:18726995 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Trps1 transcriptional repressor GATA binding 1 acts_upstream_of_or_within ISO MGI:107191|MGI:95484 (PMID:18363966) RGD PMID:18363966 NCBI chr 7:81,916,668...82,142,733
Ensembl chr 7:81,921,601...82,141,905
JBrowse link
G Zswim2 zinc finger, SWIM-type containing 2 acts_upstream_of_or_within ISO (PMID:16522193) RGD PMID:16522193 NCBI chr 3:68,993,422...69,015,441
Ensembl chr 3:68,995,027...69,015,411
JBrowse link
positive regulation of intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 IDA MMO:0000679 RGD PMID:23729662 RGD:329403056 NCBI chr13:77,747,752...77,833,952
Ensembl chr13:77,768,468...77,833,951
JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:14963330), (PMID:21199865), (PMID:21262771)
MGI:2158306 (PMID:14502238)
UniProt
RGD
PMID:14502238 PMID:14963330 PMID:21199865 PMID:21262771 GO_REF:0000024 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 involved_in IMP
ISS
ISO
IEA
PMID:27031958
GO_REF:0000024
(PMID:17289999), (PMID:27031958)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:17289999 PMID:27031958 PMID:27031958 GO_REF:0000024 GO_REF:0000107, RGD:14390051 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcap31 B-cell receptor-associated protein 31 involved_in ISO (PMID:21183955) RGD PMID:21183955 NCBI chr  X:151,397,567...151,429,666
Ensembl chr  X:151,397,576...151,428,506
JBrowse link
G Bcl2l11 Bcl2-like 11 involved_in ISO (PMID:21671007) RGD PMID:21671007 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 involved_in ISO (PMID:17938203) RGD PMID:17938203 NCBI chr 1:15,088,436...15,117,666
Ensembl chr 1:15,070,894...15,148,832
JBrowse link
G Becn1 beclin 1 involved_in IMP
ISS
ISO
PMID:27031958
GO_REF:0000024
(PMID:27031958)
UniProt
RGD
PMID:27031958 PMID:27031958 GO_REF:0000024, RGD:14390051 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bid BH3 interacting domain death agonist involved_in ISO
IEA
IBA
(PMID:21262771)
GO_REF:0000104
GO_REF:0000033
RGD
UniProt
GO_Central
PMID:21262771 GO_REF:0000033 GO_REF:0000104 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
ISO
GO_REF:0000024
(MGI:5705719|PMID:23429263)
UniProt
RGD
PMID:23429263 GO_REF:0000024 MGI:5705719 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase acts_upstream_of_or_within ISO MGI:3793294 (PMID:17938250) RGD PMID:17938250 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
JBrowse link
G Cav1 caveolin 1 involved_in ISO
IEA
(PMID:21382479)
GO_REF:0000107
RGD
Ensembl
PMID:21382479 GO_REF:0000107 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Clu clusterin involved_in ISS
ISO
GO_REF:0000024
(PMID:21567405)
UniProt
RGD
PMID:21567405 GO_REF:0000024 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cyct cytochrome c, testis acts_upstream_of_or_within ISO (PMID:16757556) RGD PMID:16757556 NCBI chr 3:61,290,090...61,297,158
Ensembl chr 3:60,913,562...61,297,158
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 involved_in ISS
ISO
IEA
IBA
GO_REF:0000024
(PMID:27031958)
GO_REF:0000107
GO_REF:0000118
GO_REF:0000033
UniProt
RGD
Ensembl
TreeGrafter
GO_Central
PMID:27031958 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Dnm1l dynamin 1-like involved_in ISO (PMID:20850011) RGD PMID:20850011 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Ei24 EI24, autophagy associated transmembrane protein acts_upstream_of_or_within ISO (PMID:17981155) RGD PMID:17981155 NCBI chr 8:36,494,289...36,510,653
Ensembl chr 8:36,494,289...36,510,571
JBrowse link
G Fis1 fission, mitochondrial 1 involved_in ISO
IEA
(PMID:21183955)
GO_REF:0000107
RGD
Ensembl
PMID:21183955 GO_REF:0000107 NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377
JBrowse link
G Flcn folliculin acts_upstream_of_or_within ISO MGI:4348628 (PMID:21258407) RGD PMID:21258407 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
G Gsdme gasdermin E involved_in ISO (PMID:21522185) RGD PMID:21522185 NCBI chr 4:79,258,799...79,321,129
Ensembl chr 4:79,257,804...79,320,806
JBrowse link
G Il19 interleukin 19 acts_upstream_of_or_within ISO MGI:3605069 (PMID:23468852) RGD PMID:23468852 NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473
JBrowse link
G Il20ra interleukin 20 receptor subunit alpha acts_upstream_of_or_within ISO MGI:1890472 (PMID:23468852) RGD PMID:23468852 NCBI chr 1:14,424,215...14,494,226
Ensembl chr 1:14,451,228...14,493,602
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase involved_in ISO
IEA
(PMID:16116473)
GO_REF:0000107
RGD
Ensembl
PMID:16116473 GO_REF:0000107 NCBI chr 5:141,888,318...141,916,945
Ensembl chr 5:141,888,326...141,903,794
JBrowse link
G Mir16 microRNA 16 involved_in ISO RNAcentral:URS00003D1AE3_9606 (PMID:16166262) RGD PMID:16166262 NCBI chr 2:153,245,349...153,245,443
Ensembl chr 2:153,245,349...153,245,443
JBrowse link
G Mir27b microRNA 27b acts_upstream_of_or_within ISO UniProtKB:P01375 (PMID:31124343) RGD PMID:31124343 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529
JBrowse link
G Nherf1 NHERF family PDZ scaffold protein 1 involved_in ISO (PMID:20012548) RGD PMID:20012548 NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598
JBrowse link
G Nkx3-1 NK3 homeobox 1 involved_in ISO (PMID:17486276) RGD PMID:17486276 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator involved_in ISO
IMP
ISS
(PMID:27031958)
GO_REF:0000024
RGD
UniProt
PMID:27031958 PMID:27031958 GO_REF:0000024, RGD:14390051 NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281
JBrowse link
G Plagl2 PLAG1 like zinc finger 2 acts_upstream_of_or_within ISO (PMID:11832486) RGD PMID:11832486 NCBI chr 3:141,695,322...141,708,516
Ensembl chr 3:141,695,322...141,708,503
JBrowse link
G Plekhf1 pleckstrin homology and FYVE domain containing 1 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:16188880)
GO_Central
RGD
PMID:16188880 GO_REF:0000033 NCBI chr 1:90,908,304...90,915,862
Ensembl chr 1:90,904,742...90,915,820
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:21454712) RGD PMID:21454712 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Prkra protein activator of interferon induced protein kinase EIF2AK2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:12181197)
Ensembl
RGD
PMID:12181197 GO_REF:0000107 NCBI chr 3:61,575,447...61,594,393
Ensembl chr 3:61,575,447...61,594,347
JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in ISO (PMID:19767770) RGD PMID:19767770 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 acts_upstream_of_or_within ISO (PMID:10490590) RGD PMID:10490590 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121
JBrowse link
G S100a8 S100 calcium binding protein A8 involved_in ISS
ISO
GO_REF:0000024
(PMID:19935772)
UniProt
RGD
PMID:19935772 GO_REF:0000024 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
JBrowse link
G S100a9 S100 calcium binding protein A9 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:19935772)
Ensembl
UniProt
RGD
PMID:19935772 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
JBrowse link
G Septin4 septin 4 involved_in ISO (PMID:21185211) RGD PMID:21185211 NCBI chr10:72,366,729...72,390,764
Ensembl chr10:72,366,873...72,390,768
JBrowse link
G Siah1 siah E3 ubiquitin protein ligase 1 involved_in ISO
IEA
(PMID:21185211)
GO_REF:0000107
RGD
Ensembl
PMID:21185211 GO_REF:0000107 NCBI chr19:20,378,908...20,402,512
Ensembl chr19:20,378,439...20,403,808
JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 involved_in ISO
IBA
(PMID:21262771), (PMID:24709986)
GO_REF:0000033
RGD
GO_Central
PMID:21262771 PMID:24709986 GO_REF:0000033 NCBI chr12:20,907,410...20,940,232
Ensembl chr12:20,907,435...20,939,752
JBrowse link
G Taf6 TATA-box binding protein associated factor 6 involved_in ISO (PMID:20096117) RGD PMID:20096117 NCBI chr12:17,055,864...17,064,244
Ensembl chr12:17,055,873...17,064,247
JBrowse link
G Tp53 tumor protein p53 involved_in ISS
IMP
ISO
IEA
GO_REF:0000024
PMID:27031958
(PMID:14963330), (PMID:27031958)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:14963330 PMID:27031958 PMID:27031958 GO_REF:0000024 GO_REF:0000107, RGD:14390051 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif5a eukaryotic translation initiation factor 5A involved_in ISO (PMID:15371445) RGD PMID:15371445 NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656
JBrowse link
G Mir186 microRNA 186 acts_upstream_of ISO (PMID:27714074) RGD PMID:27714074 NCBI chr 2:246,582,806...246,582,891
Ensembl chr 2:246,582,806...246,582,891
JBrowse link
G Msx1 msh homeobox 1 involved_in ISO (PMID:15705871) RGD PMID:15705871 NCBI chr14:72,961,036...72,964,970
Ensembl chr14:72,961,148...72,964,966
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO (PMID:10962037) RGD PMID:10962037 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Rps7 ribosomal protein S7 involved_in ISO (PMID:17310983) RGD PMID:17310983 NCBI chr 6:45,266,200...45,271,064
Ensembl chr 6:45,223,980...45,271,145
JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 involved_in ISO (MGI:5553386|PMID:24523556) RGD PMID:24523556 MGI:5553386 NCBI chr 2:233,750,838...233,784,817
Ensembl chr 2:233,750,838...233,784,784
JBrowse link
G Ubb ubiquitin B acts_upstream_of_or_within ISO (PMID:17571083) RGD PMID:17571083 NCBI chr10:47,247,630...47,249,335
Ensembl chr10:47,245,637...47,249,333
JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbh1 F-box DNA helicase 1 acts_upstream_of_or_within ISO (PMID:23361013) RGD PMID:23361013 NCBI chr17:66,749,506...66,787,590
Ensembl chr17:66,749,534...66,787,590
JBrowse link
G Mtch2 mitochondrial carrier 2 acts_upstream_of_or_within ISO MGI:2449949|MGI:5566664 (PMID:26219591) RGD PMID:26219591 NCBI chr 3:76,830,549...76,850,189
Ensembl chr 3:76,830,413...76,850,189
JBrowse link
G Nacc2 NACC family member 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:22926524)
Ensembl
RGD
PMID:22926524 GO_REF:0000107 NCBI chr 3:8,879,952...8,946,660
Ensembl chr 3:8,883,065...8,946,660
JBrowse link
G Pias4 protein inhibitor of activated STAT, 4 acts_upstream_of_or_within ISO (PMID:16816390) RGD PMID:16816390 NCBI chr 7:8,546,312...8,559,838
Ensembl chr 7:8,546,312...8,559,808
JBrowse link
G Plscr1 phospholipid scramblase 1 acts_upstream_of_or_within ISO (PMID:12509439) RGD PMID:12509439 NCBI chr 8:92,784,279...92,804,698
Ensembl chr 8:92,784,356...92,804,692
JBrowse link
G Rad9a RAD9 checkpoint clamp component A acts_upstream_of_or_within ISO MGI:2442925 (PMID:15983387) RGD PMID:15983387 NCBI chr 1:201,488,511...201,553,582
Ensembl chr 1:201,487,136...201,553,608
JBrowse link
G Rps3 ribosomal protein S3 involved_in ISO (PMID:22510408) RGD PMID:22510408 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680
JBrowse link
G Skil SKI-like proto-oncogene acts_upstream_of_or_within ISO MGI:2387096 (PMID:10811619) RGD PMID:10811619 NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080
JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpl26 ribosomal protein L26 involved_in ISO (PMID:16213212)
(MGI:5882892|PMID:16213212)
RGD PMID:16213212 MGI:5882892 NCBI chr10:53,610,836...53,613,966
Ensembl chr10:53,610,421...53,613,966
JBrowse link
G Steap3 STEAP3 metalloreductase acts_upstream_of_or_within ISO MGI:4398911 (PMID:18617898) RGD PMID:18617898 NCBI chr13:31,351,954...31,397,344
Ensembl chr13:31,351,954...31,396,519
JBrowse link
G Tp73 tumor protein p73 acts_upstream_of_or_within ISO MGI:2442925|MGI:98834 (PMID:15983387) RGD PMID:15983387 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128
JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death involved_in ISO
IEA
(PMID:21716255)
GO_REF:0000107
(MGI:5474549|PMID:21716255)
RGD
Ensembl
PMID:21716255 GO_REF:0000107 MGI:5474549 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nox1 NADPH oxidase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3616995 (PMID:19661248)
Ensembl
RGD
PMID:19661248 GO_REF:0000107 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236
JBrowse link
G Park7 Parkinsonism associated deglycase acts_upstream_of_or_within ISO (PMID:22555455) RGD PMID:22555455 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Sfpq splicing factor proline and glutamine rich involved_in ISO (PMID:15790595) RGD PMID:15790595 NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472
JBrowse link
G Sod1 superoxide dismutase 1 involved_in ISO
IEA
(PMID:12551919)
GO_REF:0000107
RGD
Ensembl
PMID:12551919 GO_REF:0000107 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Vnn1 vanin 1 involved_in ISO (MGI:3052282|PMID:15282320) RGD PMID:15282320 MGI:3052282 NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
JBrowse link
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 IMP RGD PMID:28386847 RGD:329337357 NCBI chr13:77,747,752...77,833,952
Ensembl chr13:77,768,468...77,833,951
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:23858059)
(MGI:5543313|PMID:23858059)
RGD PMID:23858059 MGI:5543313 NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in ISO UniProtKB:Q9WVS6 (PMID:23858059)
(MGI:5543313|PMID:23858059)
RGD PMID:23858059 MGI:5543313 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mmp2 matrix metallopeptidase 2 IMP RGD PMID:27614125 RGD:329961568 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Ralbp1 ralA binding protein 1 IMP RGD PMID:23788031 RGD:12904719 NCBI chr 9:105,456,425...105,493,235
Ensembl chr 9:105,456,425...105,492,707
JBrowse link
positive regulation of TRAIL-activated apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf3 activating transcription factor 3 involved_in ISO (PMID:24939851) RGD PMID:24939851 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    cellular process 18769
      signal transduction 7163
        positive regulation of signal transduction 1727
          positive regulation of apoptotic signaling pathway 190
            positive regulation of extrinsic apoptotic signaling pathway + 62
            positive regulation of intrinsic apoptotic signaling pathway + 76
Path 2
Term Annotations click to browse term
  biological_process 20292
    biological regulation 13633
      regulation of biological process 13220
        signaling 7729
          signal transduction 7163
            regulation of signal transduction 3182
              positive regulation of signal transduction 1727
                positive regulation of apoptotic signaling pathway 190
                  positive regulation of extrinsic apoptotic signaling pathway + 62
                  positive regulation of intrinsic apoptotic signaling pathway + 76
paths to the root