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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of apoptotic signaling pathway
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Accession:GO:2001235 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway.
Synonyms:exact_synonym: positive regulation of apoptotic signalling pathway


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positive regulation of apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07025928.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr16:55,834,458...55,835,117 JBrowse link
G AABR07052430.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 3:52,997,922...52,998,650 JBrowse link
G Adora2a adenosine A2a receptor acts_upstream_of_or_within ISO MGI:2155985 (MGI:1860411|PMID:10845921) RGD PMID:10845921 MGI:1860411 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 acts_upstream_of_or_within ISO MGI:1889507 (MGI:3603971|PMID:16183742) RGD PMID:16183742 MGI:3603971 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Bid BH3 interacting domain death agonist acts_upstream_of_or_within ISO (MGI:84156|PMID:8918887) RGD PMID:8918887 MGI:84156 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Bmf Bcl2 modifying factor acts_upstream_of_or_within ISO (MGI:2158578|PMID:11546872) RGD PMID:11546872 MGI:2158578 NCBI chr 3:110,303,515...110,324,125
Ensembl chr 3:110,306,067...110,324,084
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta acts_upstream_of_or_within ISO (MGI:3710042|PMID:17367784) RGD PMID:17367784 MGI:3710042 NCBI chr14:86,208,876...86,297,727
Ensembl chr14:86,208,901...86,297,652
JBrowse link
G Casp2 caspase 2 acts_upstream_of_or_within ISO MGI:1889507 (MGI:3603971|PMID:16183742) RGD PMID:16183742 MGI:3603971 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1889507 (MGI:3603971|PMID:16183742)
RGD PMID:16183742, PMID:21873635 MGI:3603971, RGD:13792537 NCBI chr 7:36,395,665...36,408,588
Ensembl chr 7:36,395,665...36,408,588
JBrowse link
G Ctsc cathepsin C acts_upstream_of_or_within ISO MGI:107285 (MGI:4838939|PMID:20435891) RGD PMID:20435891 MGI:4838939 NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983
JBrowse link
G Ctsh cathepsin H acts_upstream_of_or_within ISO MGI:109553 (MGI:4838939|PMID:20435891) RGD PMID:20435891 MGI:4838939 NCBI chr 8:97,439,155...97,458,293
Ensembl chr 8:97,439,161...97,458,287
JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:19903888)
UniProt
Ensembl
RGD
PMID:19903888 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:14,889,263...15,060,286
Ensembl chr 3:14,889,510...15,060,286
JBrowse link
G Daxx death-domain associated protein acts_upstream_of_or_within ISO MGI:104662 (MGI:4942266|PMID:10684855) RGD PMID:10684855 MGI:4942266 NCBI chr20:5,480,103...5,485,962
Ensembl chr20:5,480,103...5,485,926
JBrowse link
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 acts_upstream_of_or_within ISO MGI:3574590 (MGI:3573962|PMID:15680327) RGD PMID:15680327 MGI:3573962 NCBI chr17:26,785,017...26,795,723
Ensembl chr17:26,785,029...26,797,161
JBrowse link
G Fas Fas cell surface death receptor involved_in ISO (PMID:11096076) RGD PMID:11096076 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Ifnb1 interferon beta 1 involved_in ISO (PMID:10918594), (PMID:11337497) RGD PMID:10918594 PMID:11337497 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Il19 interleukin 19 acts_upstream_of_or_within ISO (MGI:2653146|PMID:12370360) RGD PMID:12370360 MGI:2653146 NCBI chr13:47,663,592...47,677,869
Ensembl chr13:47,664,080...47,670,407
JBrowse link
G Inca1 inhibitor of CDK, cyclin A1 interacting protein 1 acts_upstream_of_or_within ISO UniProtKB:Q8WYH8 (MGI:5287344|PMID:21750715) RGD PMID:21750715 MGI:5287344 NCBI chr10:57,309,722...57,322,140
Ensembl chr10:57,309,972...57,317,985
JBrowse link
G Ing5 inhibitor of growth family, member 5 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2144284 (MGI:5287344|PMID:21750715)
RGD PMID:21750715, PMID:21873635 MGI:5287344, RGD:13792537 NCBI chr 9:100,932,932...100,950,233
Ensembl chr 9:100,932,545...100,952,416
JBrowse link
G Inhbb inhibin subunit beta B involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:98957 (MGI:4454604|PMID:20454446)
Ensembl
RGD
PMID:20454446 GO_REF:0000107 MGI:4454604 NCBI chr13:35,436,532...35,442,222
Ensembl chr13:35,436,532...35,442,222
JBrowse link
G Jak2 Janus kinase 2 acts_upstream_of_or_within ISO (MGI:3036919|PMID:15012602) RGD PMID:15012602 MGI:3036919 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Maged1 MAGE family member D1 acts_upstream_of_or_within ISO MGI:1929608 (MGI:3848096|PMID:19268530), (MGI:4359364|PMID:17488777) RGD PMID:17488777 PMID:19268530 MGI:3848096 MGI:4359364 NCBI chr  X:63,803,194...63,809,715
Ensembl chr  X:63,803,189...63,809,861
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 acts_upstream_of_or_within ISO MGI:1346862 (MGI:3619752|PMID:16458303) RGD PMID:16458303 MGI:3619752 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1346861 (MGI:3619752|PMID:16458303)
Ensembl
RGD
PMID:16458303 GO_REF:0000107 MGI:3619752 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor acts_upstream_of_or_within ISO MGI:2447604 (MGI:2677658|PMID:14517295) RGD PMID:14517295 MGI:2677658 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 acts_upstream_of_or_within ISO (MGI:4829576|PMID:20530871) RGD PMID:20530871 MGI:4829576 NCBI chr15:34,493,163...34,502,238
Ensembl chr15:34,493,138...34,504,326
JBrowse link
G Ngfr nerve growth factor receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:1859527|PMID:10764727)
Ensembl
RGD
PMID:10764727 GO_REF:0000107 MGI:1859527 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Nkx3-1 NK3 homeobox 1 involved_in ISO (PMID:20599703) RGD PMID:20599703 NCBI chr15:51,065,316...51,067,908
Ensembl chr15:51,065,316...51,068,421
JBrowse link
G Osm oncostatin M acts_upstream_of_or_within ISO (MGI:3036919|PMID:15012602) RGD PMID:15012602 MGI:3036919 NCBI chr14:84,457,487...84,469,426
Ensembl chr14:84,465,515...84,470,409
JBrowse link
G Pdcd7 programmed cell death 7 acts_upstream_of_or_within ISO (MGI:1333591|PMID:10037816) RGD PMID:10037816 MGI:1333591 NCBI chr 8:70,860,671...70,875,471
Ensembl chr 8:70,860,671...70,875,471
JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within ISO MGI:1197015 (MGI:4942266|PMID:10684855) RGD PMID:10684855 MGI:4942266 NCBI chr 8:63,002,515...63,034,310
Ensembl chr 8:63,004,870...63,034,226
JBrowse link
G Prkcd protein kinase C, delta involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3581090|PMID:15731106)
Ensembl
RGD
PMID:15731106 GO_REF:0000107 MGI:3581090 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
G Pten phosphatase and tensin homolog acts_upstream_of_or_within ISO MGI:1857937 (MGI:2180890|PMID:9778245) RGD PMID:9778245 MGI:2180890 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G RGD1560831 similar to 40S ribosomal protein S3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:52,997,847...52,998,669 JBrowse link
G Rps3 ribosomal protein S3 involved_in IBA
ISO
PMID:21873635
(PMID:14988002)
RGD PMID:14988002, PMID:21873635 RGD:13792537 NCBI chr 1:164,435,868...164,441,167
Ensembl chr 1:164,435,878...164,441,167
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO (PMID:18758450) RGD PMID:18758450 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 acts_upstream_of_or_within ISO MGI:1336991 (MGI:3612718|PMID:16044147) RGD PMID:16044147 MGI:3612718 NCBI chr 5:24,402,895...24,419,651
Ensembl chr 5:24,410,863...24,416,888
JBrowse link
G Tp63 tumor protein p63 acts_upstream_of_or_within ISO (MGI:1289874|PMID:9774969) RGD PMID:9774969 MGI:1289874 NCBI chr11:78,234,853...78,456,559
Ensembl chr11:78,234,800...78,456,501
JBrowse link
G Tp73 tumor protein p73 acts_upstream_of_or_within ISO PR:Q9QXE4-2 (MGI:3612718|PMID:16044147) RGD PMID:16044147 MGI:3612718 NCBI chr 5:171,355,876...171,415,354
Ensembl chr 5:171,355,876...171,415,354
JBrowse link
G Tpd52l1 TPD52 like 1 involved_in ISO
IBA
(PMID:14761963)
PMID:21873635
RGD PMID:14761963, PMID:21873635 RGD:13792537 NCBI chr 1:28,454,949...28,578,736
Ensembl chr 1:28,454,966...28,576,553
JBrowse link
G Traf7 TNF receptor associated factor 7 involved_in ISO (PMID:15001576) RGD PMID:15001576 NCBI chr10:13,874,444...13,893,090
Ensembl chr10:13,874,456...13,892,997
JBrowse link
G Trim39 tripartite motif-containing 39 involved_in IBA
ISO
PMID:21873635
(PMID:19100260)
RGD PMID:19100260, PMID:21873635 RGD:13792537 NCBI chr20:2,500,691...2,514,546
Ensembl chr20:2,500,689...2,514,546
JBrowse link
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
ISO
GO_REF:0000024
(MGI:5648772|PMID:26015568), (MGI:5796067|PMID:26949185)
UniProt
RGD
PMID:26015568 PMID:26949185 GO_REF:0000024 MGI:5648772 MGI:5796067 NCBI chr 9:100,829,593...100,840,498
Ensembl chr 9:100,829,552...100,840,504
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO MGI:1913418 (MGI:5525071|PMID:22240901) RGD PMID:22240901 MGI:5525071 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO
IBA
(PMID:14676213)
PMID:21873635
UniProtKB:O55033 (MGI:5613475|PMID:16835242)
RGD PMID:14676213 PMID:16835242, PMID:21873635 MGI:5613475, RGD:13792537 NCBI chr 8:108,787,797...108,847,779
Ensembl chr 8:108,787,798...108,847,779
JBrowse link
G Nck2 NCK adaptor protein 2 involved_in ISO
IBA
UniProtKB:Q99M51 (MGI:5613475|PMID:16835242)
PMID:21873635
RGD PMID:16835242, PMID:21873635 MGI:5613475, RGD:13792537 NCBI chr 9:50,246,767...50,373,307
Ensembl chr 9:50,247,692...50,373,284
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISO (MGI:5619464|PMID:21216966) RGD PMID:21216966 MGI:5619464 NCBI chr18:63,415,298...63,489,240
Ensembl chr18:63,415,306...63,488,027
JBrowse link
G Rnf183 ring finger protein 183 involved_in ISO (PMID:29507230) RGD PMID:29507230 NCBI chr 5:78,283,722...78,292,729
Ensembl chr 5:78,284,879...78,285,451
JBrowse link
G Serinc3 serine incorporator 3 acts_upstream_of_or_within ISO (MGI:2671011|PMID:12486168) RGD PMID:12486168 MGI:2671011 NCBI chr 3:160,018,643...160,038,078
Ensembl chr 3:160,018,646...160,038,078
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (MGI:5607229|PMID:20955178) RGD PMID:20955178 MGI:5607229 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Spop speckle type BTB/POZ protein acts_upstream_of_or_within ISO MGI:102851 (MGI:4836774|PMID:20811152) RGD PMID:20811152 MGI:4836774 NCBI chr10:83,231,187...83,311,987
Ensembl chr10:83,231,238...83,311,592
JBrowse link
positive regulation of extrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen involved_in ISO (PMID:10406457) RGD PMID:10406457 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr2 angiotensin II receptor, type 2 involved_in ISO (PMID:10406457) RGD PMID:10406457 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Bcl10 BCL10, immune signaling adaptor involved_in
acts_upstream_of_or_within
IBA
ISO
ISS
PMID:21873635
(MGI:1355482|PMID:10753917)
GO_REF:0000024
(PMID:11466612)
RGD
UniProt
PMID:10753917 PMID:11466612, PMID:21873635 GO_REF:0000024 MGI:1355482, RGD:13792537 NCBI chr 2:251,805,392...251,814,957
Ensembl chr 2:251,805,392...251,814,957
JBrowse link
G Bcl2l14 BCL2 like 14 involved_in ISO (PMID:11054413) RGD PMID:11054413 NCBI chr 4:168,139,964...168,183,726
Ensembl chr 4:168,142,271...168,183,096
JBrowse link
G Bid BH3 interacting domain death agonist involved_in IBA
ISO
PMID:21873635
(PMID:21459798)
RGD PMID:21459798, PMID:21873635 RGD:13792537 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Casp8 caspase 8 acts_upstream_of_or_within ISO MGI:1889507 (MGI:3603971|PMID:16183742) RGD PMID:16183742 MGI:3603971 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Cav1 caveolin 1 involved_in ISO
IEA
(PMID:21382479)
GO_REF:0000107
RGD
Ensembl
PMID:21382479 GO_REF:0000107 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Cyld CYLD lysine 63 deubiquitinase involved_in IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:21525013)
Ensembl
RGD
PMID:21525013, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr19:19,264,984...19,323,817
Ensembl chr19:19,265,164...19,315,357
JBrowse link
G Dedd2 death effector domain containing 2 involved_in ISO (PMID:11741985) RGD PMID:11741985 NCBI chr 1:82,073,024...82,089,028
Ensembl chr 1:82,072,544...82,088,275
JBrowse link
G Fadd Fas associated via death domain involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1336166|MGI:2154952 (MGI:5486419|PMID:22675671)
(PMID:21525013)
RGD PMID:21525013 PMID:22675671, PMID:21873635 MGI:5486419, RGD:13792537 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G G0s2 G0/G1switch 2 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:19706769)
UniProt
RGD
PMID:19706769, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr13:112,004,140...112,005,052
Ensembl chr13:112,004,140...112,005,052
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in IDA PMID:23907461 UniProt PMID:23907461 RGD:8553942 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G Hyal2 hyaluronidase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3851310|PMID:19366691)
Ensembl
RGD
PMID:19366691 GO_REF:0000107 MGI:3851310 NCBI chr 8:116,324,062...116,328,978
Ensembl chr 8:116,324,040...116,328,978
JBrowse link
G Itm2c integral membrane protein 2C involved_in ISO (MGI:4821078|PMID:14592447) RGD PMID:14592447 MGI:4821078 NCBI chr 9:92,916,469...92,930,306
Ensembl chr 9:92,916,469...92,930,279
JBrowse link
G Ltbr lymphotoxin beta receptor involved_in ISO (PMID:20732415) RGD PMID:20732415 NCBI chr 4:157,822,838...157,829,291
Ensembl chr 4:157,822,840...157,829,241
JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 involved_in ISO (PMID:19240112) RGD PMID:19240112 NCBI chr11:72,829,407...72,865,815
Ensembl chr11:72,829,238...72,865,902
Ensembl chr11:72,829,238...72,865,902
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3578073|PMID:15858817)
Ensembl
RGD
PMID:15858817 GO_REF:0000107 MGI:3578073 NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (PMID:21803845) RGD PMID:21803845 NCBI chr 8:63,002,515...63,034,310
Ensembl chr 8:63,004,870...63,034,226
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:1857277 (MGI:80946|PMID:8666928) RGD PMID:8666928 MGI:80946 NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692
JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:16964285) RGD PMID:16964285 NCBI chr 1:199,438,029...199,439,062
Ensembl chr 1:199,437,832...199,439,210
JBrowse link
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:5000222 (MGI:4437982|PMID:19136968)
Ensembl
RGD
PMID:19136968 GO_REF:0000107 MGI:4437982 NCBI chr 3:147,793,014...147,809,941
Ensembl chr 3:147,793,017...147,809,919
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in
acts_upstream_of_or_within
ISO (PMID:21525013), (PMID:22274400)
MGI:104798 (MGI:5510543|PMID:19498109)
RGD PMID:19498109 PMID:21525013 PMID:22274400 MGI:5510543 NCBI chr17:31,537,580...31,569,904
Ensembl chr17:31,537,591...31,569,904
JBrowse link
G Runx3 RUNX family transcription factor 3 acts_upstream_of_or_within ISO MGI:2179229 (MGI:2177980|PMID:11955451) RGD PMID:11955451 MGI:2177980 NCBI chr 5:153,507,093...153,531,137
Ensembl chr 5:153,507,093...153,531,137
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 acts_upstream_of_or_within ISO MGI:3045799 (MGI:3040721|PMID:14976225) RGD PMID:14976225 MGI:3040721 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777
JBrowse link
G Siglec1 sialic acid binding Ig like lectin 1 acts_upstream_of_or_within ISO MGI:3617694 (MGI:5469747|PMID:23408841) RGD PMID:23408841 MGI:5469747 NCBI chr 3:123,612,067...123,631,718
Ensembl chr 3:123,612,067...123,631,109
JBrowse link
G Tnf tumor necrosis factor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A involved_in IBA
ISO
PMID:21873635
(PMID:21525013)
RGD PMID:21525013, PMID:21873635 RGD:13792537 NCBI chr10:12,995,904...12,997,930
Ensembl chr10:12,995,904...12,997,930
JBrowse link
G Tnfsf10 TNF superfamily member 10 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3576402|PMID:15632112)
(PMID:20097879), (PMID:21525171), (PMID:22266862)
RGD PMID:15632112 PMID:20097879 PMID:21525171 PMID:22266862, PMID:21873635 MGI:3576402, RGD:13792537 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Tnfsf12 TNF superfamily member 12 involved_in ISO (PMID:21525013) RGD PMID:21525013 NCBI chr10:56,290,780...56,300,137
Ensembl chr10:56,290,780...56,300,077
JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in ISO (PMID:21525013) RGD PMID:21525013 NCBI chr 3:2,746,061...2,770,690
Ensembl chr 3:2,746,075...2,770,620
JBrowse link
G Wwox WW domain-containing oxidoreductase involved_in ISO (MGI:3851310|PMID:19366691) RGD PMID:19366691 MGI:3851310 NCBI chr19:46,761,353...47,695,247 JBrowse link
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO (MGI:67275|PMID:8358790) RGD PMID:8358790 MGI:67275 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Ctnna1 catenin alpha 1 acts_upstream_of_or_within ISO MGI:2677796 (MGI:5315030|PMID:22411810) RGD PMID:22411810 MGI:5315030 NCBI chr18:27,923,229...28,055,972
Ensembl chr18:27,923,572...28,055,960
JBrowse link
G Dapk3 death-associated protein kinase 3 involved_in IMP PMID:21172653 UniProt PMID:21172653 RGD:8554227 NCBI chr 7:11,392,436...11,400,855
Ensembl chr 7:11,392,437...11,400,805
JBrowse link
G Htra2 HtrA serine peptidase 2 involved_in ISO (PMID:20125124) RGD PMID:20125124 NCBI chr 4:113,883,671...113,886,833
Ensembl chr 4:113,883,670...113,886,994
JBrowse link
G Inhba inhibin subunit beta A involved_in ISO
ISS
(PMID:8267637)
GO_REF:0000024
RGD
UniProt
PMID:8267637 GO_REF:0000024 NCBI chr17:51,894,869...51,919,998
Ensembl chr17:51,898,217...51,912,496
JBrowse link
G Jak3 Janus kinase 3 involved_in ISO (MGI:3719947|PMID:16020505) RGD PMID:16020505 MGI:3719947 NCBI chr16:20,107,471...20,120,678
Ensembl chr16:20,109,200...20,120,668
JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857478 (MGI:3038547|PMID:15039234)
Ensembl
RGD
PMID:15039234 GO_REF:0000107 MGI:3038547 NCBI chr10:66,732,460...66,928,706
Ensembl chr10:66,690,133...66,928,903
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha acts_upstream_of_or_within ISO (MGI:2183839|PMID:12115603) RGD PMID:12115603 MGI:2183839 NCBI chr 1:219,439,953...219,443,570
Ensembl chr 1:219,439,953...219,443,570
JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha acts_upstream_of_or_within ISO (MGI:2675215|PMID:12944463) RGD PMID:12944463 MGI:2675215 NCBI chr 1:60,717,386...60,736,629
Ensembl chr 1:60,717,386...60,736,609
JBrowse link
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta involved_in ISO (PMID:21172653) RGD PMID:21172653 NCBI chr 8:55,279,278...55,311,768
Ensembl chr 8:55,279,373...55,301,320
JBrowse link
G Ret ret proto-oncogene involved_in ISO (PMID:10921886) RGD PMID:10921886 NCBI chr 4:150,202,170...150,249,196
Ensembl chr 4:150,202,058...150,244,372
JBrowse link
G Srpx sushi-repeat-containing protein, X-linked acts_upstream_of_or_within ISO MGI:3706175 (MGI:3703665|PMID:17088259) RGD PMID:17088259 MGI:3703665 NCBI chr  X:14,146,618...14,220,756
Ensembl chr  X:14,150,038...14,220,662
JBrowse link
G Tgfb2 transforming growth factor, beta 2 acts_upstream_of_or_within ISO (MGI:67124|PMID:8206089) RGD PMID:8206089 MGI:67124 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Unc5b unc-5 netrin receptor B involved_in IMP PMID:21172653 UniProt PMID:21172653 RGD:8554227 NCBI chr20:30,339,680...30,406,593
Ensembl chr20:30,339,673...30,406,295
JBrowse link
G Wwox WW domain-containing oxidoreductase acts_upstream_of_or_within ISO (MGI:3851310|PMID:19366691) RGD PMID:19366691 MGI:3851310 NCBI chr19:46,761,353...47,695,247 JBrowse link
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1b bone morphogenetic protein receptor type 1B acts_upstream_of_or_within ISO MGI:1927616|MGI:95484 (MGI:3819026|PMID:18363966) RGD PMID:18363966 MGI:3819026 NCBI chr 2:247,392,195...247,662,026
Ensembl chr 2:247,403,920...247,446,882
JBrowse link
G Faf1 Fas associated factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:77677|PMID:8524870)
Ensembl
RGD
PMID:8524870 GO_REF:0000107 MGI:77677 NCBI chr 5:129,370,767...129,738,393
Ensembl chr 5:129,448,879...129,738,252
JBrowse link
G Mal mal, T-cell differentiation protein acts_upstream_of_or_within ISO (MGI:3687876|PMID:12776198) RGD PMID:12776198 MGI:3687876 NCBI chr 3:120,209,647...120,233,655
Ensembl chr 3:120,209,647...120,233,655
JBrowse link
G Pea15 proliferation and apoptosis adaptor protein 15 acts_upstream_of_or_within ISO (MGI:3687663|PMID:10588860) RGD PMID:10588860 MGI:3687663 NCBI chr13:90,579,844...90,589,466
Ensembl chr13:90,579,846...90,589,466
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:15705586) RGD PMID:15705586 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO (MGI:84500|PMID:8940094) RGD PMID:8940094 MGI:84500 NCBI chr13:98,513,600...98,539,347
Ensembl chr13:98,513,570...98,530,724
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in ISO
IEA
(PMID:9391078)
GO_REF:0000107
RGD
Ensembl
PMID:9391078 GO_REF:0000107 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777
JBrowse link
G Skil SKI-like proto-oncogene acts_upstream_of_or_within ISO MGI:2387096 (MGI:1858539|PMID:10811619) RGD PMID:10811619 MGI:1858539 NCBI chr 2:115,862,932...115,891,304
Ensembl chr 2:115,866,701...115,891,097
JBrowse link
G Stk3 serine/threonine kinase 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:104798|MGI:1928487|MGI:1929004 (MGI:4420852|PMID:20080598)
Ensembl
RGD
PMID:20080598 GO_REF:0000107 MGI:4420852 NCBI chr 7:73,617,926...73,883,896
Ensembl chr 7:73,618,644...73,883,812
JBrowse link
G Stk4 serine/threonine kinase 4 acts_upstream_of_or_within ISO MGI:104798|MGI:1928487 (MGI:4420852|PMID:20080598) RGD PMID:20080598 MGI:4420852 NCBI chr 3:160,467,552...160,546,540
Ensembl chr 3:160,467,552...160,546,540
JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:18726995) RGD PMID:18726995 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Trps1 transcriptional repressor GATA binding 1 acts_upstream_of_or_within ISO MGI:107191|MGI:95484 (MGI:3819026|PMID:18363966) RGD PMID:18363966 MGI:3819026 NCBI chr 7:90,085,895...90,320,430
Ensembl chr 7:90,090,828...90,318,221
JBrowse link
G Zswim2 zinc finger, SWIM-type containing 2 acts_upstream_of_or_within ISO (MGI:3692348|PMID:16522193) RGD PMID:16522193 MGI:3692348 NCBI chr 3:71,274,341...71,295,641
Ensembl chr 3:71,274,337...71,295,629
JBrowse link
positive regulation of intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within
IEA
ISO
ISS
GO_REF:0000107
MGI:2158306 (MGI:3692043|PMID:14502238)
(PMID:14963330), (PMID:21199865), (PMID:21262771)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:14502238 PMID:14963330 PMID:21199865 PMID:21262771 GO_REF:0000024 GO_REF:0000107 MGI:3692043 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 involved_in IMP
ISS
ISO
PMID:27031958
GO_REF:0000024
(PMID:17289999), (PMID:27031958)
UniProt
RGD
PMID:17289999 PMID:27031958, PMID:27031958 GO_REF:0000024, RGD:14390051 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcap31 B-cell receptor-associated protein 31 involved_in ISO (PMID:21183955) RGD PMID:21183955 NCBI chr  X:157,094,365...157,126,397
Ensembl chr  X:157,095,937...157,126,393
JBrowse link
G Bcl2l11 BCL2 like 11 involved_in ISO (PMID:21671007) RGD PMID:21671007 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 involved_in ISO (PMID:17938203) RGD PMID:17938203 NCBI chr 1:15,799,753...15,828,838
Ensembl chr 1:15,782,477...15,860,624
JBrowse link
G Becn1 beclin 1 involved_in IMP
ISO
ISS
PMID:27031958
(PMID:27031958)
GO_REF:0000024
RGD
UniProt
PMID:27031958, PMID:27031958 GO_REF:0000024, RGD:14390051 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bid BH3 interacting domain death agonist involved_in IBA
ISO
PMID:21873635
(PMID:21262771)
RGD PMID:21262771, PMID:21873635 RGD:13792537 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
ISO
GO_REF:0000024
(MGI:5705719|PMID:23429263)
UniProt
RGD
PMID:23429263 GO_REF:0000024 MGI:5705719 NCBI chr 9:100,829,593...100,840,498
Ensembl chr 9:100,829,552...100,840,504
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase acts_upstream_of_or_within ISO MGI:3793294 (MGI:3790365|PMID:17938250) RGD PMID:17938250 MGI:3790365 NCBI chr 3:120,373,604...120,404,910
Ensembl chr 3:120,373,604...120,404,910
JBrowse link
G Cav1 caveolin 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:21382479)
Ensembl
RGD
PMID:21382479 GO_REF:0000107 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Clu clusterin involved_in ISS
ISO
GO_REF:0000024
(PMID:21567405)
UniProt
RGD
PMID:21567405 GO_REF:0000024 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Cyct cytochrome c, testis acts_upstream_of_or_within ISO (MGI:3652666|PMID:16757556) RGD PMID:16757556 MGI:3652666 NCBI chr 3:63,204,779...63,211,847
Ensembl chr 3:62,818,502...63,211,845
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 involved_in ISS
IBA
IEA
ISO
GO_REF:0000024
PMID:21873635
GO_REF:0000107
(PMID:27031958)
UniProt
Ensembl
RGD
PMID:27031958, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Dnm1l dynamin 1-like involved_in ISO (PMID:20850011) RGD PMID:20850011 NCBI chr11:88,830,968...88,882,271
Ensembl chr11:88,830,957...88,880,198
JBrowse link
G Ei24 EI24, autophagy associated transmembrane protein acts_upstream_of_or_within ISO (MGI:3764759|PMID:17981155) RGD PMID:17981155 MGI:3764759 NCBI chr 8:39,254,883...39,271,238
Ensembl chr 8:39,254,889...39,266,959
JBrowse link
G Fis1 fission, mitochondrial 1 involved_in ISO (PMID:21183955) RGD PMID:21183955 NCBI chr12:22,750,485...22,765,324
Ensembl chr12:22,750,485...22,765,308
JBrowse link
G Flcn folliculin acts_upstream_of_or_within ISO MGI:4348628 (MGI:5050037|PMID:21258407) RGD PMID:21258407 MGI:5050037 NCBI chr10:46,153,185...46,172,331
Ensembl chr10:46,153,188...46,172,309
JBrowse link
G Gsdme gasdermin E involved_in ISO (PMID:21522185) RGD PMID:21522185 NCBI chr 4:79,934,075...79,999,678
Ensembl chr 4:79,934,887...79,989,572
JBrowse link
G Il19 interleukin 19 acts_upstream_of_or_within ISO MGI:3605069 (MGI:5491082|PMID:23468852) RGD PMID:23468852 MGI:5491082 NCBI chr13:47,663,592...47,677,869
Ensembl chr13:47,664,080...47,670,407
JBrowse link
G Il20ra interleukin 20 receptor subunit alpha acts_upstream_of_or_within ISO MGI:1890472 (MGI:5491082|PMID:23468852) RGD PMID:23468852 MGI:5491082 NCBI chr 1:15,180,328...15,222,785
Ensembl chr 1:15,180,328...15,222,785
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase involved_in ISO
IEA
(PMID:16116473)
GO_REF:0000107
RGD
Ensembl
PMID:16116473 GO_REF:0000107 NCBI chr 5:147,750,976...147,779,627
Ensembl chr 5:147,750,973...147,761,983
JBrowse link
G Nkx3-1 NK3 homeobox 1 involved_in ISO
ISS
(PMID:17486276)
GO_REF:0000024
RGD
UniProt
PMID:17486276 GO_REF:0000024 NCBI chr15:51,065,316...51,067,908
Ensembl chr15:51,065,316...51,068,421
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator involved_in ISO
ISS
IMP
(PMID:27031958)
GO_REF:0000024
RGD
UniProt
PMID:27031958, PMID:27031958 GO_REF:0000024, RGD:14390051 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524
JBrowse link
G Plagl2 PLAG1 like zinc finger 2 acts_upstream_of_or_within ISO (MGI:2179174|PMID:11832486) RGD PMID:11832486 MGI:2179174 NCBI chr 3:148,709,564...148,722,777
Ensembl chr 3:148,709,531...148,722,742
JBrowse link
G Plekhf1 pleckstrin homology and FYVE domain containing 1 acts_upstream_of_or_within ISO (MGI:3611133|PMID:16188880) RGD PMID:16188880 MGI:3611133 NCBI chr 1:94,609,041...94,616,565
Ensembl chr 1:94,609,377...94,610,854
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:21454712) RGD PMID:21454712 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
JBrowse link
G Prkra protein activator of interferon induced protein kinase EIF2AK2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:2386461|PMID:12181197)
Ensembl
RGD
PMID:12181197 GO_REF:0000107 MGI:2386461 NCBI chr 3:63,489,081...63,507,918
Ensembl chr 3:63,489,074...63,507,926
JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in ISO (PMID:19767770) RGD PMID:19767770 NCBI chr10:34,149,717...34,155,198
Ensembl chr10:34,149,717...34,155,198
Ensembl chr12:34,149,717...34,155,198
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 acts_upstream_of_or_within ISO (MGI:1345788|PMID:10490590) RGD PMID:10490590 MGI:1345788 NCBI chr15:34,470,796...34,479,741
Ensembl chr15:34,470,796...34,479,741
JBrowse link
G S100a8 S100 calcium binding protein A8 involved_in ISS
ISO
GO_REF:0000024
(PMID:19935772)
UniProt
RGD
PMID:19935772 GO_REF:0000024 NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354
JBrowse link
G S100a9 S100 calcium binding protein A9 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:19935772)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:19935772 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276
JBrowse link
G Septin4 septin 4 involved_in ISO (PMID:21185211) RGD PMID:21185211 NCBI chr10:74,860,068...74,884,196
Ensembl chr10:74,861,714...74,884,196
JBrowse link
G Siah1 siah E3 ubiquitin protein ligase 1 involved_in ISO (PMID:21185211) RGD PMID:21185211 NCBI chr19:21,372,163...21,395,773
Ensembl chr19:21,372,163...21,395,767
JBrowse link
G Slc9a3r1 SLC9A3 regulator 1 involved_in ISO (PMID:20012548) RGD PMID:20012548 NCBI chr10:103,713,045...103,730,145
Ensembl chr10:103,713,045...103,730,145
JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 involved_in ISO
IBA
(PMID:21262771), (PMID:24709986)
PMID:21873635
RGD PMID:21262771 PMID:24709986, PMID:21873635 RGD:13792537 NCBI chr12:23,954,563...23,987,155
Ensembl chr12:23,954,574...23,987,271
JBrowse link
G Taf6 TATA-box binding protein associated factor 6 involved_in ISO (PMID:20096117) RGD PMID:20096117 NCBI chr12:19,320,269...19,328,706
Ensembl chr12:19,320,271...19,328,637
JBrowse link
G Tp53 tumor protein p53 involved_in ISS
ISO
IMP
GO_REF:0000024
(PMID:14963330), (PMID:27031958)
UniProt
RGD
PMID:14963330 PMID:27031958, PMID:27031958 GO_REF:0000024, RGD:14390051 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif5a eukaryotic translation initiation factor 5A involved_in ISO (PMID:15371445) RGD PMID:15371445 NCBI chr10:56,527,075...56,531,615
Ensembl chr10:56,527,085...56,531,483
JBrowse link
G Msx1 msh homeobox 1 involved_in ISO (PMID:15705871) RGD PMID:15705871 NCBI chr14:77,712,262...77,716,061
Ensembl chr14:77,712,240...77,716,059
JBrowse link
G Rpl11 ribosomal protein L11 involved_in ISO (MGI:5883206|PMID:22262176) RGD PMID:22262176 MGI:5883206 NCBI chr 5:154,390,809...154,394,412
Ensembl chr 5:154,388,140...154,394,328
JBrowse link
G Rps7 ribosomal protein S7 involved_in ISO (PMID:17310983) RGD PMID:17310983 NCBI chr 6:47,899,525...47,904,389
Ensembl chr 6:47,899,525...47,904,437
JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 involved_in ISO (MGI:5553386|PMID:24523556) RGD PMID:24523556 MGI:5553386 NCBI chr 2:250,709,812...250,744,216
Ensembl chr 2:250,709,439...250,744,196
JBrowse link
G Ubb ubiquitin B acts_upstream_of_or_within ISO (PMID:17571083) RGD PMID:17571083 NCBI chr10:48,880,231...48,881,896
Ensembl chr10:48,881,049...48,881,881
JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbh1 F-box DNA helicase 1 acts_upstream_of_or_within ISO (PMID:23361013) RGD PMID:23361013 NCBI chr17:70,399,093...70,437,151
Ensembl chr17:70,399,049...70,437,144
JBrowse link
G Mtch2 mitochondrial carrier 2 acts_upstream_of_or_within ISO MGI:2449949|MGI:5566664 (MGI:5662300|PMID:26219591) RGD PMID:26219591 MGI:5662300 NCBI chr 3:79,678,141...79,695,356
Ensembl chr 3:79,678,201...79,694,006
JBrowse link
G Nacc2 NACC family member 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:22926524)
Ensembl
RGD
PMID:22926524 GO_REF:0000107 NCBI chr 3:3,508,084...3,574,787
Ensembl chr 3:3,510,041...3,574,787
JBrowse link
G Pias4 protein inhibitor of activated STAT, 4 acts_upstream_of_or_within ISO (MGI:5009403|PMID:16816390) RGD PMID:16816390 MGI:5009403 NCBI chr 7:11,414,565...11,428,090
Ensembl chr 7:11,414,446...11,428,552
JBrowse link
G Plscr1 phospholipid scramblase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5284813|PMID:12509439)
Ensembl
RGD
PMID:12509439 GO_REF:0000107 MGI:5284813 NCBI chr 8:99,625,523...99,645,882
Ensembl chr 8:99,625,545...99,725,217
JBrowse link
G Rad9a RAD9 checkpoint clamp component A acts_upstream_of_or_within ISO MGI:2442925 (MGI:3584078|PMID:15983387) RGD PMID:15983387 MGI:3584078 NCBI chr 1:219,443,347...219,450,574
Ensembl chr 1:219,444,092...219,450,451
JBrowse link
G Rps3 ribosomal protein S3 involved_in ISO (PMID:22510408) RGD PMID:22510408 NCBI chr 1:164,435,868...164,441,167
Ensembl chr 1:164,435,878...164,441,167
JBrowse link
G Skil SKI-like proto-oncogene acts_upstream_of_or_within ISO MGI:2387096 (MGI:1858539|PMID:10811619) RGD PMID:10811619 MGI:1858539 NCBI chr 2:115,862,932...115,891,304
Ensembl chr 2:115,866,701...115,891,097
JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpl26 ribosomal protein L26 involved_in ISO (PMID:16213212)
(MGI:5882892|PMID:16213212)
RGD PMID:16213212 MGI:5882892 NCBI chr10:55,492,417...55,495,547
Ensembl chr10:55,492,404...55,496,012
JBrowse link
G Steap3 STEAP3 metalloreductase acts_upstream_of_or_within ISO MGI:4398911 (MGI:4367682|PMID:18617898) RGD PMID:18617898 MGI:4367682 NCBI chr13:36,257,220...36,274,144
Ensembl chr13:36,257,112...36,290,531
JBrowse link
G Tp73 tumor protein p73 acts_upstream_of_or_within ISO MGI:2442925|MGI:98834 (MGI:3584078|PMID:15983387) RGD PMID:15983387 MGI:3584078 NCBI chr 5:171,355,876...171,415,354
Ensembl chr 5:171,355,876...171,415,354
JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death involved_in ISO (PMID:21716255)
(MGI:5474549|PMID:21716255)
RGD PMID:21716255 MGI:5474549 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nox1 NADPH oxidase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3616995 (MGI:4881403|PMID:19661248)
Ensembl
RGD
PMID:19661248 GO_REF:0000107 MGI:4881403 NCBI chr  X:104,909,328...104,932,508
Ensembl chr  X:104,909,326...104,932,508
JBrowse link
G Park7 Parkinsonism associated deglycase acts_upstream_of_or_within ISO (MGI:5543357|PMID:22555455) RGD PMID:22555455 MGI:5543357 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Sfpq splicing factor proline and glutamine rich involved_in ISO (PMID:15790595) RGD PMID:15790595 NCBI chr 5:145,079,803...145,088,517
Ensembl chr 5:145,079,803...145,088,498
JBrowse link
G Sod1 superoxide dismutase 1 involved_in ISO (PMID:12551919) RGD PMID:12551919 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:23858059)
(MGI:5543313|PMID:23858059)
RGD PMID:23858059 MGI:5543313 NCBI chr 2:184,230,191...184,309,805
Ensembl chr 2:184,231,260...184,309,664
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in ISO UniProtKB:Q9WVS6 (PMID:23858059)
(MGI:5543313|PMID:23858059)
RGD PMID:23858059 MGI:5543313 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Ralbp1 ralA binding protein 1 IMP RGD PMID:23788031 RGD:12904719 NCBI chr 9:113,579,107...113,598,477
Ensembl chr 9:113,579,107...113,598,480
JBrowse link
positive regulation of TRAIL-activated apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf3 activating transcription factor 3 involved_in ISO (PMID:24939851) RGD PMID:24939851 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (PMID:19962668) RGD PMID:19962668 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 involved_in ISO
IEA
(PMID:19962668)
GO_REF:0000107
RGD
Ensembl
PMID:19962668 GO_REF:0000107 NCBI chr 7:23,543,125...23,594,170
Ensembl chr 7:23,544,215...23,594,133
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    signaling 7458
      positive regulation of signaling 1930
        positive regulation of signal transduction 1597
          positive regulation of apoptotic signaling pathway 160
            positive regulation of extrinsic apoptotic signaling pathway + 60
            positive regulation of intrinsic apoptotic signaling pathway + 70
Path 2
Term Annotations click to browse term
  biological_process 19491
    biological regulation 13515
      regulation of biological process 12773
        regulation of cellular process 12275
          regulation of cell death 1768
            regulation of programmed cell death 1592
              regulation of apoptotic process 1556
                positive regulation of apoptotic process 615
                  positive regulation of apoptotic signaling pathway 160
                    positive regulation of extrinsic apoptotic signaling pathway + 60
                    positive regulation of intrinsic apoptotic signaling pathway + 70
paths to the root