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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of apoptotic signaling pathway
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Accession:GO:2001233 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of apoptotic signaling pathway.
Synonyms:exact_synonym: regulation of apoptotic signalling pathway


show annotations for term's descendants           Sort by:
regulation of apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp8 caspase 8 acts_upstream_of_or_within ISO MGI:103223 (PMID:15456877) RGD PMID:15456877 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Pmp22 peripheral myelin protein 22 acts_upstream_of_or_within ISO MGI:1856217 (PMID:23847051) RGD PMID:23847051 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714 		JBrowse link
G Ppia peptidylprolyl isomerase A involved_in ISS
ISO		 GO_REF:0000024
(PMID:23180369)		 UniProt
RGD		 PMID:23180369 GO_REF:0000024 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601 		JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr14:21,006,522...21,007,284
Ensembl chr14:21,006,538...21,007,310 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor acts_upstream_of_or_within ISO MGI:1261423 (PMID:15456877) RGD PMID:15456877 NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377 		JBrowse link
negative regulation of apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aatf apoptosis antagonizing transcription factor acts_upstream_of_or_within ISO MGI:1930187 (PMID:17488777) RGD PMID:17488777 NCBI chr10:69,299,029...69,392,207
Ensembl chr10:69,299,037...69,392,201 		JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in ISO
ISS		 (PMID:15946935)
GO_REF:0000024		 RGD
UniProt		 PMID:15946935 GO_REF:0000024 NCBI chr 1:229,865,662...229,973,253
Ensembl chr 1:229,865,662...229,939,162 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO MGI:2675387 (PMID:18436203) RGD PMID:18436203 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in
acts_upstream_of_or_within		 ISO (PMID:20097879)
(PMID:11546872)		 RGD PMID:11546872 PMID:20097879 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bdnf brain-derived neurotrophic factor involved_in ISO RNAcentral:URS000055128B_10090 (PMID:26708520) RGD PMID:26708520 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bmf Bcl2 modifying factor acts_upstream_of_or_within ISO (PMID:11546872) RGD PMID:11546872 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145 		JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger acts_upstream_of_or_within ISO MGI:99161 (PMID:11290297) RGD PMID:11290297 NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690 		JBrowse link
G Cdk11b cyclin-dependent kinase 11B involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3043373 (PMID:15060143)		 Ensembl
RGD		 PMID:15060143 GO_REF:0000107 NCBI chr 5:166,212,761...166,238,883
Ensembl chr 5:166,212,829...166,238,876 		JBrowse link
G Cth cystathionine gamma-lyase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:22244329)		 Ensembl
RGD		 PMID:22244329 GO_REF:0000107 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within ISO MGI:1858008|MGI:2148567|MGI:98957 (PMID:15131783), (PMID:20454446) RGD PMID:15131783 PMID:20454446 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in ISO UniProtKB:P35411 (PMID:10869418) RGD PMID:10869418 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in IGI PMID:10869418 ARUK-UCL PMID:10869418 RGD:4892026 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014 		JBrowse link
G Ep300 E1A binding protein p300 IMP cardiac myocytes RGD PMID:22562121 RGD:7327216 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 acts_upstream_of_or_within ISO MGI:4888719 (PMID:21209208) RGD PMID:21209208 NCBI chr 7:130,632,368...130,659,353
Ensembl chr 7:130,633,348...130,659,168 		JBrowse link
G Gata4 GATA binding protein 4 involved_in ISO (PMID:25590961) RGD PMID:25590961 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Gnai2 G protein subunit alpha i2 IMP RGD PMID:25633408 RGD:13507311 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Gnai3 G protein subunit alpha i3 IMP RGD PMID:25633408 RGD:13507311 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 IMP RGD PMID:23690069 RGD:13792722 NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 acts_upstream_of_or_within ISO (PMID:15731106) RGD PMID:15731106 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Igbp1 immunoglobulin binding protein 1 acts_upstream_of_or_within ISO MGI:2448686|MGI:3056510 (PMID:15499020) RGD PMID:15499020 NCBI chr  X:65,582,832...65,605,078
Ensembl chr  X:65,582,821...65,606,049 		JBrowse link
G Ing2 inhibitor of growth family, member 2 acts_upstream_of_or_within ISO MGI:4879096 (PMID:21124965) RGD PMID:21124965 NCBI chr16:44,573,592...44,584,180
Ensembl chr16:44,575,597...44,583,482 		JBrowse link
G Madd MAP-kinase activating death domain acts_upstream_of_or_within ISO (PMID:14735464) RGD PMID:14735464 NCBI chr 3:77,114,330...77,157,865
Ensembl chr 3:77,114,314...77,157,701 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 acts_upstream_of_or_within ISO MGI:104798 (PMID:16260493) RGD PMID:16260493 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 involved_in ISO (PMID:10756100) RGD PMID:10756100 NCBI chr 7:120,526,732...120,536,982
Ensembl chr 7:120,526,732...120,536,982 		JBrowse link
G Maz MYC associated zinc finger protein involved_in ISO (PMID:25487955) RGD PMID:25487955 NCBI chr 1:181,629,742...181,635,193
Ensembl chr 1:181,629,729...181,650,408 		JBrowse link
G Mdm2 MDM2 proto-oncogene IMP caspase-2, caspase-3 RGD PMID:19850968 RGD:2317361 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Meis3 Meis homeobox 3 acts_upstream_of_or_within ISO (PMID:21059917) RGD PMID:21059917 NCBI chr 1:76,861,267...76,872,691
Ensembl chr 1:76,861,924...76,872,691 		JBrowse link
G Mir146a microRNA 146a acts_upstream_of ISO (PMID:28433754) RGD PMID:28433754 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610 		JBrowse link
G Mir210 microRNA 210 involved_in ISO (PMID:26780211) RGD PMID:26780211 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454 		JBrowse link
G Mnt MAX network transcriptional repressor acts_upstream_of_or_within ISO MGI:2678322 (PMID:12970171) RGD PMID:12970171 NCBI chr10:59,699,208...59,714,848
Ensembl chr10:59,699,585...59,714,835 		JBrowse link
G Mrtfa myocardin related transcription factor A acts_upstream_of_or_within ISO (PMID:12019265) RGD PMID:12019265 NCBI chr 7:112,544,305...112,714,418
Ensembl chr 7:112,544,312...112,714,418 		JBrowse link
G Nanos3 nanos C2HC-type zinc finger 3 acts_upstream_of_or_within ISO MGI:2682607|MGI:99702 (PMID:18436203) RGD PMID:18436203 NCBI chr19:23,978,465...23,988,933
Ensembl chr19:23,985,504...23,988,932 		JBrowse link
G Nog noggin involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1862000 (PMID:16712836)		 Ensembl
RGD		 PMID:16712836 GO_REF:0000107 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 involved_in ISO
IEA		 (PMID:19429166)
GO_REF:0000107		 RGD
Ensembl		 PMID:19429166 GO_REF:0000107 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877 		JBrowse link
G Pam16 presequence translocase associated motor 16 acts_upstream_of_or_within ISO (PMID:20719856) RGD PMID:20719856 NCBI chr10:10,942,534...10,950,654
Ensembl chr10:10,943,001...10,950,649 		JBrowse link
G Pcgf2 polycomb group ring finger 2 acts_upstream_of_or_within ISO MGI:88174 (PMID:11290297) RGD PMID:11290297 NCBI chr10:82,682,563...82,694,563
Ensembl chr10:82,683,553...82,693,406 		JBrowse link
G Ppef2 protein phosphatase with EF-hand domain 2 involved_in ISO (PMID:20674765) RGD PMID:20674765 NCBI chr14:15,797,414...15,831,620
Ensembl chr14:15,797,435...15,831,491 		JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within ISO MGI:109284 (PMID:15148382) RGD PMID:15148382 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO MGI:1202717 (PMID:15148382) RGD PMID:15148382 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174 		JBrowse link
G Qars1 glutaminyl-tRNA synthetase 1 involved_in ISO
IEA		 (PMID:11096076)
GO_REF:0000107		 RGD
Ensembl		 PMID:11096076 GO_REF:0000107 NCBI chr 8:109,207,705...109,215,738
Ensembl chr 8:109,207,705...109,215,739 		JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in IMP PMID:24027266 ARUK-UCL PMID:24027266 RGD:14397580 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO
IBA		 (PMID:21075086)
GO_REF:0000033		 RGD
GO_Central		 PMID:21075086 GO_REF:0000033 NCBI chr 7:130,527,313...130,542,567
Ensembl chr 7:130,527,316...130,543,633 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO RNAcentral:URS0000330617_9606 (PMID:31124343) RGD PMID:31124343 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Wnt16 Wnt family member 16 involved_in ISO (PMID:17200136) RGD PMID:17200136 NCBI chr 4:50,820,968...50,831,380
Ensembl chr 4:50,820,968...50,831,380 		JBrowse link
G Wnt4 Wnt family member 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:88276|MGI:96571 (PMID:20454446)
GO_REF:0000107		 RGD
Ensembl		 PMID:20454446 GO_REF:0000107 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
negative regulation of death-inducing signaling complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nol3 nucleolar protein 3 involved_in IDA PMID:12191471
PMID:15383280		 UniProt PMID:12191471 PMID:15383280 RGD:631884, RGD:10047289 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:21785459) RGD PMID:21785459 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2l1 Bcl2-like 1 involved_in ISO
IEA
ISS		 (PMID:29507230)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:29507230 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Creb3 cAMP responsive element binding protein 3 involved_in ISO (PMID:16940180) RGD PMID:16940180 NCBI chr 5:57,817,865...57,823,233
Ensembl chr 5:57,817,832...57,824,390 		JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 involved_in IMP
ISO		 PMID:15665855
(PMID:15665855)		 RGD PMID:15665855 PMID:15665855 RGD:1558627 NCBI chr 3:77,952,589...77,993,513
Ensembl chr 3:77,952,540...77,993,456 		JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1341830|MGI:99682 (PMID:22240901)		 Ensembl
RGD		 PMID:22240901 GO_REF:0000107 NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in ISO
IBA		 (PMID:15102845)
GO_REF:0000033		 RGD
GO_Central		 PMID:15102845 GO_REF:0000033 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:12150907), (PMID:20625543) RGD PMID:12150907 PMID:20625543 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:12150907), (PMID:20625543) RGD PMID:12150907 PMID:20625543 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in ISO (PMID:23453807) RGD PMID:23453807 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:21857923) RGD PMID:21857923 NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Ngf nerve growth factor involved_in NAS PMID:21266243 ParkinsonsUK-UCL PMID:21266243 RGD:10047230 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:23453807)
GO_REF:0000107
UniProtKB:P58281 (PMID:23453807)		 ParkinsonsUK-UCL
RGD
Ensembl		 PMID:23453807 GO_REF:0000024 GO_REF:0000107 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO UniProtKB:Q99LX0 (PMID:14652021) RGD PMID:14652021 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 acts_upstream_of_or_within ISO MGI:2181360 (PMID:20811152) RGD PMID:20811152 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISS
ISO		 GO_REF:0000024
(PMID:21113145)
(PMID:10973942), (PMID:11439185), (PMID:12150907), (PMID:21113145), (PMID:23453807)		 ParkinsonsUK-UCL
RGD		 PMID:10973942 PMID:11439185 PMID:12150907 PMID:21113145 PMID:23453807 GO_REF:0000024 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO (PMID:21216966) RGD PMID:21216966 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
G Selenos selenoprotein S involved_in ISO
IEA		 (PMID:17210132)
GO_REF:0000107		 RGD
Ensembl		 PMID:17210132 GO_REF:0000107 NCBI chr 1:119,659,779...119,669,546
Ensembl chr 1:119,659,751...119,669,833 		JBrowse link
G Syvn1 synoviolin 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:12459480), (PMID:17059562)
MGI:2679656 (PMID:15611074)		 RGD PMID:12459480 PMID:15611074 PMID:17059562 NCBI chr 1:203,339,235...203,346,137
Ensembl chr 1:203,339,619...203,346,152 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in
acts_upstream_of_or_within		 ISO (PMID:21075086)
MGI:1913418 (PMID:22240901)		 RGD PMID:21075086 PMID:22240901 NCBI chr 7:130,527,313...130,542,567
Ensembl chr 7:130,527,316...130,543,633 		JBrowse link
G Txndc12 thioredoxin domain containing 12 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:18628206)
GO_REF:0000107		 RGD
Ensembl		 PMID:18628206 GO_REF:0000107 NCBI chr 5:123,587,854...123,612,886
Ensembl chr 5:123,586,781...123,612,870 		JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in ISO (PMID:16571599) RGD PMID:16571599 NCBI chr14:73,810,478...73,834,993
Ensembl chr14:73,810,404...73,835,602 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO
IEA
IMP		 (PMID:19135031)
GO_REF:0000107
PMID:20625543		 RGD
Ensembl		 PMID:19135031 PMID:20625543 GO_REF:0000107, RGD:10047191 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hyou1 hypoxia up-regulated 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:17116640)		 Ensembl
RGD		 PMID:17116640 GO_REF:0000107 NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:O15354 (PMID:17116640), (PMID:23453807)		 Ensembl
RGD		 PMID:17116640 PMID:23453807 GO_REF:0000107 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
negative regulation of extrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO
IEA		 (PMID:9884026)
GO_REF:0000107		 RGD
Ensembl		 PMID:9884026 GO_REF:0000107 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241 		JBrowse link
G Ar androgen receptor involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:21310825)		 Ensembl
UniProt
RGD		 PMID:21310825 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Birc6 baculoviral IAP repeat-containing 6 involved_in ISO (PMID:14765125) RGD PMID:14765125 NCBI chr 6:20,722,922...20,916,396
Ensembl chr 6:20,722,922...20,916,434 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO		 GO_REF:0000107
(PMID:15070745)		 Ensembl
RGD		 PMID:15070745 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator involved_in
acts_upstream_of_or_within		 ISO (PMID:22266862), (PMID:9208847)
MGI:109324|MGI:2154952 (PMID:22675671)		 RGD PMID:9208847 PMID:22266862 PMID:22675671 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Cttn cortactin involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1924375 (PMID:22660580)		 Ensembl
RGD		 PMID:22660580 GO_REF:0000107 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164 		JBrowse link
G Dab2 DAB adaptor protein 2 acts_upstream_of_or_within ISO (PMID:15734730) RGD PMID:15734730 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476 		JBrowse link
G Fcmr Fc mu receptor acts_upstream_of_or_within ISO (PMID:15632112) RGD PMID:15632112 NCBI chr13:42,337,363...42,351,706
Ensembl chr13:42,337,414...42,351,653 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within ISO MGI:104995 (PMID:15288121) RGD PMID:15288121 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit acts_upstream_of_or_within ISO MGI:104990 (PMID:15288121) RGD PMID:15288121 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISO (PMID:16636664) RGD PMID:16636664 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Htt huntingtin involved_in IMP
IEA
ISO		 GO_REF:0000107
(PMID:19240112)		 Ensembl
RGD		 PMID:19240112 PMID:17124493 GO_REF:0000107, RGD:6902918 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA
IDA		 (PMID:16942485)
GO_REF:0000107
PMID:17023532		 RGD
Ensembl		 PMID:16942485 PMID:17023532 GO_REF:0000107, RGD:1600072 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Il19 interleukin 19 acts_upstream_of_or_within ISO (PMID:23468852) RGD PMID:23468852 NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:10429671) RGD PMID:10429671 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il7 interleukin 7 acts_upstream_of_or_within ISO (PMID:10429671) RGD PMID:10429671 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075 		JBrowse link
G Itga6 integrin subunit alpha 6 involved_in ISO (PMID:21310825) RGD PMID:21310825 NCBI chr 3:56,604,512...56,689,428
Ensembl chr 3:56,617,268...56,689,428 		JBrowse link
G Itgav integrin subunit alpha V involved_in ISO (PMID:10708943) RGD PMID:10708943 NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639 		JBrowse link
G Lgals3 galectin 3 involved_in ISO
IBA
IEA		 (PMID:22761016)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:22761016 GO_REF:0000033 GO_REF:0000107 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025 		JBrowse link
G Lmna lamin A/C involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:21151901)		 Ensembl
RGD		 PMID:21151901 GO_REF:0000107 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423 		JBrowse link
G Mir142 microRNA 142 involved_in ISO UniProtKB:P01137 (PMID:26572508) RGD PMID:26572508 NCBI chr10:72,557,864...72,557,950
Ensembl chr10:72,557,857...72,557,967 		JBrowse link
G Mir199a2 microRNA 199a-2 involved_in ISO (PMID:22821565) RGD PMID:22821565 NCBI chr13:74,582,954...74,583,063
Ensembl chr13:74,582,954...74,583,063 		JBrowse link
G Nol3 nucleolar protein 3 involved_in ISO
IEA
IBA		 (PMID:9560245)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:9560245 GO_REF:0000033 GO_REF:0000107 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250 		JBrowse link
G Nrp1 neuropilin 1 involved_in ISO (PMID:21828096) RGD PMID:21828096 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633 		JBrowse link
G Pak5 p21 (RAC1) activated kinase 5 acts_upstream_of_or_within ISO (PMID:12897128) RGD PMID:12897128 NCBI chr 3:123,395,678...123,703,967
Ensembl chr 3:123,396,497...123,703,930 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO
ISS		 (PMID:21785459)
GO_REF:0000024		 RGD
ParkinsonsUK-UCL		 PMID:21785459 GO_REF:0000024 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Peli3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (PMID:24113711)
MGI:5441750 (PMID:23950925)		 RGD PMID:23950925 PMID:24113711 NCBI chr 1:202,230,034...202,242,900
Ensembl chr 1:202,232,228...202,242,857 		JBrowse link
G Phip pleckstrin homology domain interacting protein acts_upstream_of_or_within ISO (PMID:17636024) RGD PMID:17636024 NCBI chr 8:83,776,802...83,891,192
Ensembl chr 8:83,781,465...83,894,283 		JBrowse link
G Prdx2 peroxiredoxin 2 acts_upstream_of_or_within ISO MGI:2668456 (PMID:15259009) RGD PMID:15259009 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
G Psme3 proteasome activator subunit 3 involved_in ISO (PMID:18309296) RGD PMID:18309296 NCBI chr10:86,257,672...86,265,458
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
G Rb1cc1 RB1-inducible coiled-coil 1 acts_upstream_of_or_within ISO MGI:3690329 (PMID:17015619) RGD PMID:17015619 NCBI chr 5:13,161,648...13,225,560
Ensembl chr 5:13,161,648...13,225,560 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in
acts_upstream_of_or_within		 ISO (PMID:21310825)
(PMID:22244329)		 RGD PMID:21310825 PMID:22244329 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:21525013)
MGI:104798|MGI:109200 (PMID:22089168)		 RGD PMID:21525013 PMID:22089168 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 acts_upstream_of_or_within ISO (PMID:11493700) RGD PMID:11493700 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908 		JBrowse link
G Scg2 secretogranin II involved_in ISO
IEA		 (PMID:14970115)
GO_REF:0000107		 RGD
Ensembl		 PMID:14970115 GO_REF:0000107 NCBI chr 9:80,803,074...80,808,646
Ensembl chr 9:80,803,075...80,821,097 		JBrowse link
G Sh3rf1 SH3 domain containing ring finger 1 involved_in ISO (PMID:21586138) RGD PMID:21586138 NCBI chr16:28,735,522...28,901,261
Ensembl chr16:28,735,440...28,901,644 		JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 involved_in ISO (PMID:21586138) RGD PMID:21586138 NCBI chr 2:142,913,924...142,931,752
Ensembl chr 2:142,914,003...142,931,950 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO
IBA		 (PMID:19767770)
GO_REF:0000033		 RGD
GO_Central		 PMID:19767770 GO_REF:0000033 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 involved_in IMP PMID:21965303 BHF-UCL PMID:21965303 RGD:14974246 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO
IEA		 (PMID:18625725)
GO_REF:0000107		 RGD
Ensembl		 PMID:18625725 GO_REF:0000107 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (PMID:11009421) RGD PMID:11009421 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 involved_in ISO (PMID:11567634) RGD PMID:11567634 NCBI chr 5:166,606,909...166,609,599
Ensembl chr 5:166,606,909...166,609,599 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (PMID:21828096) RGD PMID:21828096 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Yap1 Yes1 associated transcriptional regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:95484 (PMID:17980593)		 Ensembl
RGD		 PMID:17980593 GO_REF:0000107 NCBI chr 8:5,095,705...5,166,808
Ensembl chr 8:5,095,722...5,167,010 		JBrowse link
G Zmynd11 zinc finger, MYND-type containing 11 involved_in ISO (PMID:20732415) RGD PMID:20732415 NCBI chr17:60,542,669...60,631,913
Ensembl chr17:60,543,077...60,631,902 		JBrowse link
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 involved_in IMP PMID:18469807 UniProt PMID:18469807 RGD:8553892 NCBI chr 7:62,897,282...62,914,295
Ensembl chr 7:62,897,282...62,914,295 		JBrowse link
G Bcl2 BCL2, apoptosis regulator acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:99702 (PMID:8358790)
GO_REF:0000107		 RGD
Ensembl		 PMID:8358790 GO_REF:0000107 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l10 Bcl2-like 10 acts_upstream_of_or_within ISO (PMID:9878060) RGD PMID:9878060 NCBI chr 8:76,107,326...76,113,373
Ensembl chr 8:76,107,326...76,113,367 		JBrowse link
G Col2a1 collagen type II alpha 1 chain involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2152978 (PMID:9299161)		 Ensembl
RGD		 PMID:9299161 GO_REF:0000107 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Csf2 colony stimulating factor 2 involved_in ISO (PMID:10666185) RGD PMID:10666185 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Ctnna1 catenin alpha 1 acts_upstream_of_or_within ISO MGI:2677796 (PMID:22411810) RGD PMID:22411810 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:18322241), (PMID:18971423)
GO_REF:0000107		 RGD
Ensembl		 PMID:18322241 PMID:18971423 GO_REF:0000107 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1857803 (PMID:15817220)		 GO_Central
RGD		 PMID:15817220 GO_REF:0000033 NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483 		JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:154,335,598...154,519,006
Ensembl chr 3:154,335,400...154,518,793 		JBrowse link
G Eya3 EYA transcriptional coactivator and phosphatase 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:144,806,523...144,934,522
Ensembl chr 5:144,806,577...144,934,518 		JBrowse link
G Eya4 EYA transcriptional coactivator and phosphatase 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:22,172,275...22,415,978
Ensembl chr 1:22,172,275...22,415,976 		JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647 (PMID:16956603) RGD PMID:16956603 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in IMP PMID:18469807 UniProt PMID:18469807 RGD:8553892 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Gas1 growth arrest-specific 1 acts_upstream_of_or_within ISO (PMID:15070677) RGD PMID:15070677 NCBI chr17:4,482,168...4,485,153 JBrowse link
G Gata1 GATA binding protein 1 involved_in ISO (PMID:17167422) RGD PMID:17167422 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530 		JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in ISO
IEA		 (PMID:10921886)
GO_REF:0000107		 RGD
Ensembl		 PMID:10921886 GO_REF:0000107 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Gfral GDNF family receptor alpha like involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:16086688)		 Ensembl
RGD		 PMID:16086688 GO_REF:0000107 NCBI chr 8:76,917,894...76,963,258
Ensembl chr 8:76,918,657...76,959,425 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:17167422) RGD PMID:17167422 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:17167422) RGD PMID:17167422 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:10748004) RGD PMID:10748004 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il7 interleukin 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:8950980)		 Ensembl
RGD		 PMID:8950980 GO_REF:0000107 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075 		JBrowse link
G Klf4 KLF transcription factor 4 involved_in ISO (PMID:20551324) RGD PMID:20551324 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 involved_in IMP PMID:20551324 BHF-UCL PMID:20551324 RGD:8553940 NCBI chr 8:63,625,220...63,852,090
Ensembl chr 8:63,625,221...63,851,983 		JBrowse link
G Mapk7 mitogen-activated protein kinase 7 involved_in ISO
IEA		 UniProtKB:Q62862 (PMID:20551324)
GO_REF:0000107		 RGD
Ensembl		 PMID:20551324 GO_REF:0000107 NCBI chr10:46,170,264...46,176,262
Ensembl chr10:46,170,167...46,176,267 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in ISO (PMID:20921992) RGD PMID:20921992 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Nrg1 neuregulin 1 involved_in ISO (PMID:9553078) RGD PMID:9553078 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Pf4 platelet factor 4 involved_in ISO (PMID:10666185) RGD PMID:10666185 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365 		JBrowse link
G Prdx2 peroxiredoxin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:9115640)		 Ensembl
RGD		 PMID:9115640 GO_REF:0000107 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in ISO (PMID:20125124) RGD PMID:20125124 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
G Sgk3 serum/glucocorticoid regulated kinase family, member 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:11050396)		 Ensembl
RGD		 PMID:11050396 GO_REF:0000107 NCBI chr 5:9,345,761...9,472,243
Ensembl chr 5:9,346,040...9,415,476 		JBrowse link
G Snai2 snail family transcriptional repressor 2 acts_upstream_of_or_within
involved_in		 ISO (PMID:10518215) RGD PMID:10518215 NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200 		JBrowse link
G Stradb STE20 related adaptor beta acts_upstream_of_or_within ISO (PMID:12574163) RGD PMID:12574163 NCBI chr 9:60,414,182...60,433,084
Ensembl chr 9:60,414,182...60,433,084 		JBrowse link
G Tert telomerase reverse transcriptase involved_in ISO (PMID:10449030) RGD PMID:10449030 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:10666185), (PMID:10748004) RGD PMID:10666185 PMID:10748004 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Unc5b unc-5 netrin receptor B involved_in ISO
IEA		 (PMID:18469807)
GO_REF:0000107		 RGD
Ensembl		 PMID:18469807 GO_REF:0000107 NCBI chr20:28,697,726...28,764,474
Ensembl chr20:28,697,726...28,764,537 		JBrowse link
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:22711822) RGD PMID:22711822 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355 		JBrowse link
G Bcl2l1 Bcl2-like 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:26582200)
GO_REF:0000107		 RGD
Ensembl		 PMID:26582200 GO_REF:0000107 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Brca1 BRCA1, DNA repair associated involved_in ISO
IEA		 (PMID:23415688)
GO_REF:0000107		 RGD
Ensembl		 PMID:23415688 GO_REF:0000107 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Caps calcyphosine acts_upstream_of_or_within ISO (PMID:12466268) RGD PMID:12466268 NCBI chr 9:1,544,597...1,545,631
Ensembl chr 9:1,544,719...1,545,647 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator involved_in
acts_upstream_of_or_within		 ISO (PMID:18202225)
(PMID:26582200)		 RGD PMID:18202225 PMID:26582200 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:18846110) RGD PMID:18846110 NCBI chr  X:9,479,532...9,493,169
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Faim Fas apoptotic inhibitory molecule involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:10075978)		 GO_Central
RGD		 PMID:10075978 GO_REF:0000033 NCBI chr 8:99,543,877...99,569,499
Ensembl chr 8:99,542,405...99,560,562 		JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:26582200)
GO_REF:0000033		 RGD
GO_Central		 PMID:26582200 GO_REF:0000033 NCBI chr 7:130,632,368...130,659,353
Ensembl chr 7:130,633,348...130,659,168 		JBrowse link
G Faiml Fas apoptotic inhibitory molecule like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:99,791,849...99,810,206
Ensembl chr 8:99,791,981...99,810,228 		JBrowse link
G Fga fibrinogen alpha chain involved_in ISO (PMID:10903502) RGD PMID:10903502 NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528 		JBrowse link
G Fgb fibrinogen beta chain involved_in ISO (PMID:10903502) RGD PMID:10903502 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979 		JBrowse link
G Fgg fibrinogen gamma chain involved_in ISO (PMID:10903502) RGD PMID:10903502 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322 		JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:12221075)		 Ensembl
RGD		 PMID:12221075 GO_REF:0000107 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:18846110)		 UniProt
Ensembl
RGD		 PMID:18846110 GO_REF:0000024 GO_REF:0000107 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hgf hepatocyte growth factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:15314156)		 Ensembl
RGD		 PMID:15314156 GO_REF:0000107 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Hmgb2 high mobility group box 2 acts_upstream_of_or_within ISO MGI:2387671 (PMID:19139395) RGD PMID:19139395 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
Ensembl chr 1:32,710,658...32,713,140 		JBrowse link
G Hmox1 heme oxygenase 1 involved_in ISO
IEA		 (PMID:18202225)
GO_REF:0000107		 RGD
Ensembl		 PMID:18202225 GO_REF:0000107 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Icam1 intercellular adhesion molecule 1 involved_in ISO (PMID:10903502) RGD PMID:10903502 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Itprip inositol 1,4,5-trisphosphate receptor interacting protein acts_upstream_of_or_within ISO MGI:1916885 (PMID:20053891) RGD PMID:20053891 NCBI chr 1:246,762,804...246,786,379
Ensembl chr 1:246,762,472...246,786,408 		JBrowse link
G Nol3 nucleolar protein 3 involved_in IMP PMID:12191471
PMID:15383280		 UniProt PMID:12191471 PMID:15383280 RGD:631884, RGD:10047289 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250 		JBrowse link
G Pea15 proliferation and apoptosis adaptor protein 15 involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA		 (PMID:10442631)
(PMID:10588860)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:10442631 PMID:10588860 GO_REF:0000033 GO_REF:0000107 NCBI chr13:84,657,815...84,667,437
Ensembl chr13:84,654,870...84,667,499 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2388026|MGI:95484|MGI:99255 (PMID:16365167)		 Ensembl
RGD		 PMID:16365167 GO_REF:0000107 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase involved_in ISO
IBA
IEA
ISS		 (PMID:15069192)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:15069192 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr10:67,740,711...67,803,669
Ensembl chr10:67,740,712...67,824,434 		JBrowse link
G Rnf34 ring finger protein 34 involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(PMID:15069192)		 UniProt
GO_Central
Ensembl
RGD		 PMID:15069192 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr12:33,703,655...33,724,606
Ensembl chr12:33,703,673...33,724,586 		JBrowse link
G Serpine1 serpin family E member 1 involved_in ISO
IEA		 (PMID:18835034)
GO_REF:0000107		 RGD
Ensembl		 PMID:18835034 GO_REF:0000107 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 involved_in ISO (PMID:9391078) RGD PMID:9391078 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063 		JBrowse link
G Tmbim1 transmembrane BAX inhibitor motif containing 1 involved_in ISO
IBA
ISS		 (PMID:21107705)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:21107705 GO_REF:0000024 GO_REF:0000033 NCBI chr 9:75,871,835...75,889,366
Ensembl chr 9:75,871,835...75,889,069 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (PMID:12167698) RGD PMID:12167698 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Tnfrsf22 tumor necrosis factor receptor superfamily, member 22 acts_upstream_of_or_within ISO (PMID:12466268) RGD PMID:12466268 NCBI chr 1:198,840,452...198,860,713
Ensembl chr 1:198,840,453...198,856,309 		JBrowse link
G Ybx3 Y box binding protein 3 involved_in ISO (PMID:22711822) RGD PMID:22711822 NCBI chr 4:165,129,747...165,153,101
Ensembl chr 4:165,129,758...165,153,161 		JBrowse link
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in ISO UniProtKB:Q99LX0 (PMID:14652021) RGD PMID:14652021 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:21177249), (PMID:23261939) RGD PMID:21177249 PMID:23261939 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eno1 enolase 1 involved_in ISO UniProtKB:Q01986 (PMID:15459207) RGD PMID:15459207 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
Ensembl chr 3:160,719,951...160,731,336 		JBrowse link
G Hyou1 hypoxia up-regulated 1 involved_in IDA
IBA
IEA
ISO		 PMID:11231630
GO_REF:0000033
GO_REF:0000107
(PMID:10037731)		 GO_Central
Ensembl
RGD		 PMID:10037731 PMID:11231630 GO_REF:0000033 GO_REF:0000107, RGD:10047348 NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186 		JBrowse link
G Kdm6a lysine demethylase 6A IMP RGD PMID:30887465 RGD:151665136 NCBI chr  X:4,337,466...4,477,100
Ensembl chr  X:4,337,750...4,477,062 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 involved_in IGI
IMP		 PMID:15459207 CAFA PMID:15459207 PMID:15459207 RGD:12793039, RGD:12793039 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Nol3 nucleolar protein 3 involved_in IDA PMID:10590251 UniProt PMID:10590251 RGD:10047155 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta involved_in IEA
ISO		 GO_REF:0000107
(PMID:30496354)		 Ensembl
RGD		 PMID:30496354 GO_REF:0000107 NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:24553947) RGD PMID:24553947 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO (PMID:21075086) RGD PMID:21075086 NCBI chr 7:130,527,313...130,542,567
Ensembl chr 7:130,527,316...130,543,633 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19911006)		 Ensembl
RGD		 PMID:19911006 GO_REF:0000107 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in ISO
IEA		 (PMID:11684014)
GO_REF:0000107		 RGD
Ensembl		 PMID:11684014 GO_REF:0000107 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in ISO (PMID:12011449)
(PMID:21567405)		 RGD PMID:12011449 PMID:21567405 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bcl2l10 Bcl2-like 10 acts_upstream_of_or_within ISO (PMID:9878060) RGD PMID:9878060 NCBI chr 8:76,107,326...76,113,373
Ensembl chr 8:76,107,326...76,113,367 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:21883093) RGD PMID:21883093 NCBI chr  X:9,479,532...9,493,169
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Fignl1 fidgetin-like 1 acts_upstream_of_or_within ISO (PMID:20886204) RGD PMID:20886204 NCBI chr14:86,368,670...86,381,728
Ensembl chr14:86,368,675...86,377,455 		JBrowse link
G G2e3 G2/M-phase specific E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:3808723 (PMID:18511420) RGD PMID:18511420 NCBI chr 6:68,763,847...68,795,305
Ensembl chr 6:68,764,185...68,793,924 		JBrowse link
G Gcg glucagon involved_in ISO (PMID:19915011) RGD PMID:19915011 NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929 		JBrowse link
G Hdac1 histone deacetylase 1 acts_upstream_of_or_within ISO MGI:1097691 (PMID:21093383) RGD PMID:21093383 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Hdac2 histone deacetylase 2 acts_upstream_of_or_within ISO MGI:108086 (PMID:21093383) RGD PMID:21093383 NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Hells helicase, lymphoid specific acts_upstream_of_or_within ISO MGI:2178586 (PMID:11325543) RGD PMID:11325543 NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in ISO UniProtKB:P37840 (PMID:22045699) RGD PMID:22045699 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424 		JBrowse link
G Ivns1abp influenza virus NS1A binding protein acts_upstream_of_or_within ISO MGI:4820513 (PMID:15485691) RGD PMID:15485691 NCBI chr13:63,427,040...63,446,701
Ensembl chr13:63,427,041...63,446,701 		JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:10098834)		 Ensembl
RGD		 PMID:10098834 GO_REF:0000107 NCBI chr 3:78,355,051...78,372,946
Ensembl chr 3:78,355,048...78,372,884 		JBrowse link
G Mmp9 matrix metallopeptidase 9 involved_in IEA
ISO		 GO_REF:0000107
(PMID:22984561)		 Ensembl
RGD		 PMID:22984561 GO_REF:0000107 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Noc2l NOC2-like nucleolar associated transcriptional repressor involved_in ISO (PMID:16322561) RGD PMID:16322561 NCBI chr 5:166,820,150...166,831,949
Ensembl chr 5:166,820,161...166,831,949 		JBrowse link
G Nol3 nucleolar protein 3 involved_in IMP
IBA		 PMID:15383280
GO_REF:0000033		 GO_Central PMID:15383280 GO_REF:0000033, RGD:10047289 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISO (PMID:16839884) RGD PMID:16839884 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109 		JBrowse link
G Parl presenilin associated, rhomboid-like involved_in ISS
ISO		 GO_REF:0000024
(PMID:16839884)		 ParkinsonsUK-UCL
RGD		 PMID:16839884 GO_REF:0000024 NCBI chr11:80,594,059...80,620,506
Ensembl chr11:80,593,192...80,620,506 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:15087508) RGD PMID:15087508 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Plaur plasminogen activator, urokinase receptor involved_in ISO
IEA		 (PMID:22984561)
GO_REF:0000107		 RGD
Ensembl		 PMID:22984561 GO_REF:0000107 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595 		JBrowse link
G Ppif peptidylprolyl isomerase F involved_in ISO
ISS		 (PMID:19228691)
GO_REF:0000024		 RGD
UniProt		 PMID:19228691 GO_REF:0000024 NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913 		JBrowse link
G Rtkn2 rhotekin 2 involved_in ISO (PMID:26124677) RGD PMID:26124677 NCBI chr20:20,536,628...20,609,951
Ensembl chr20:20,525,256...20,609,951 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO
IBA		 (PMID:19767770)
GO_REF:0000033		 RGD
GO_Central		 PMID:19767770 GO_REF:0000033 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Uri1 URI1, prefoldin-like chaperone involved_in ISO
IBA		 (PMID:17936702)
GO_REF:0000033		 RGD
GO_Central		 PMID:17936702 GO_REF:0000033 NCBI chr 1:90,646,392...90,704,811
Ensembl chr 1:90,646,393...90,709,026 		JBrowse link
G Vdac2 voltage-dependent anion channel 2 involved_in ISO (PMID:12881569) RGD PMID:12881569 NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Armc10 armadillo repeat containing 10 involved_in ISO (PMID:17904127) RGD PMID:17904127 NCBI chr 4:13,399,004...13,414,594
Ensembl chr 4:13,395,207...13,414,548 		JBrowse link
G Cep63 centrosomal protein 63 acts_upstream_of_or_within ISO MGI:98834 (PMID:26158450) RGD PMID:26158450 NCBI chr 8:103,162,639...103,214,177
Ensembl chr 8:103,162,700...103,214,177 		JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in ISO (PMID:17310983) RGD PMID:17310983 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mdm4 MDM4 regulator of p53 involved_in ISO (PMID:12101245) RGD PMID:12101245 NCBI chr13:44,432,596...44,516,165
Ensembl chr13:44,406,213...44,474,226 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:18829576) RGD PMID:18829576 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA		 (PMID:23985028)
GO_REF:0000107		 RGD
Ensembl		 PMID:23985028 GO_REF:0000107 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Pttg1ip PTTG1 interacting protein acts_upstream_of_or_within ISO (PMID:24506068) RGD PMID:24506068 NCBI chr20:11,030,013...11,047,742
Ensembl chr20:11,030,015...11,047,316 		JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B acts_upstream_of_or_within ISO MGI:2672883 (PMID:12858174) RGD PMID:12858174 NCBI chr 7:69,077,024...69,108,742
Ensembl chr 7:69,078,291...69,108,633 		JBrowse link
G Rrn3 RRN3 homolog, RNA polymerase I transcription factor acts_upstream_of_or_within ISO MGI:3584037 (PMID:15989966) RGD PMID:15989966 NCBI chr10:2,129,949...2,165,381
Ensembl chr10:2,129,978...2,165,663 		JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 involved_in ISO (PMID:24523556) RGD PMID:24523556 NCBI chr 2:233,750,838...233,784,817
Ensembl chr 2:233,750,838...233,784,784 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ackr3 atypical chemokine receptor 3 involved_in ISO (PMID:20388803) RGD PMID:20388803 NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237 		JBrowse link
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of_or_within ISO (PMID:15983387) RGD PMID:15983387 NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845 		JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in ISO
IEA		 (PMID:16608847)
GO_REF:0000107		 RGD
Ensembl		 PMID:16608847 GO_REF:0000107 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bid BH3 interacting domain death agonist involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:5428930 (PMID:26219591)		 Ensembl
RGD		 PMID:26219591 GO_REF:0000107 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Ccar2 cell cycle and apoptosis regulator 2 involved_in ISO (PMID:23352644) RGD PMID:23352644 NCBI chr15:45,212,797...45,228,001
Ensembl chr15:45,212,803...45,227,636 		JBrowse link
G Cdkn2d cyclin dependent kinase inhibitor 2D involved_in ISO (PMID:15750620) RGD PMID:15750620 NCBI chr 8:19,831,874...19,834,640
Ensembl chr 8:19,831,866...19,834,674 		JBrowse link
G Clu clusterin involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:16113678)		 UniProt
Ensembl
RGD		 PMID:16113678 GO_REF:0000024 GO_REF:0000107 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 involved_in ISO (PMID:20388803) RGD PMID:20388803 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Ddias DNA damage-induced apoptosis suppressor involved_in ISO (PMID:24214091) RGD PMID:24214091 NCBI chr 1:146,906,150...146,930,462
Ensembl chr 1:146,906,154...146,930,462 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 involved_in ISO (PMID:14561758) RGD PMID:14561758 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063 		JBrowse link
G Snai1 snail family transcriptional repressor 1 involved_in ISO (PMID:15314165) RGD PMID:15314165 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969 		JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in ISO (PMID:15314165) RGD PMID:15314165 NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200 		JBrowse link
G Tmem161a transmembrane protein 161A involved_in ISO (PMID:16551573) RGD PMID:16551573 NCBI chr16:19,237,638...19,248,151
Ensembl chr16:19,238,487...19,248,087 		JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 acts_upstream_of_or_within ISO (PMID:11598139) RGD PMID:11598139 NCBI chr15:51,156,728...51,159,629
Ensembl chr15:51,146,154...51,159,625 		JBrowse link
G Trim32 tripartite motif-containing 32 involved_in ISO (PMID:18632609) RGD PMID:18632609 NCBI chr 5:79,005,139...79,016,615
Ensembl chr 5:78,999,389...79,022,018 		JBrowse link
G Usp47 ubiquitin specific peptidase 47 acts_upstream_of_or_within ISO MGI:4130032 (PMID:19966869) RGD PMID:19966869 NCBI chr 1:166,152,104...166,235,312
Ensembl chr 1:166,152,199...166,235,312 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family, AAA domain containing 5 involved_in ISO (PMID:15983387) RGD PMID:15983387 NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845 		JBrowse link
G Bcl2l12 Bcl2 like 12 acts_upstream_of_or_within ISO (PMID:20837658) RGD PMID:20837658 NCBI chr 1:95,472,272...95,480,991
Ensembl chr 1:95,472,272...95,480,991 		JBrowse link
G Cd44 CD44 molecule involved_in ISO
IEA		 (PMID:17045821)
GO_REF:0000107		 RGD
Ensembl		 PMID:17045821 GO_REF:0000107 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd74 CD74 molecule involved_in ISO
IBA
IEA
ISS		 (PMID:17045821)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
BHF-UCL		 PMID:17045821 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Ell3 elongation factor for RNA polymerase II 3 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 3:108,413,035...108,417,181
Ensembl chr 3:108,410,448...108,417,132 		JBrowse link
G Kdm1a lysine demethylase 1A involved_in ISO (PMID:17805299) RGD PMID:17805299 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:29295817)		 UniProt
Ensembl
RGD		 PMID:29295817 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:44,680,229...44,720,172
Ensembl chr 3:44,681,632...44,720,168 		JBrowse link
G Mif macrophage migration inhibitory factor involved_in ISO (PMID:17045821) RGD PMID:17045821 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
Ensembl chr 4:12,790,902...12,799,504 		JBrowse link
G Muc1 mucin 1, cell surface associated involved_in ISO (PMID:15710329) RGD PMID:15710329 NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733 		JBrowse link
G Sirt1 sirtuin 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:11672522)		 Ensembl
RGD		 PMID:11672522 GO_REF:0000107 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 involved_in ISO (PMID:15735003) RGD PMID:15735003 NCBI chr12:41,267,534...41,270,053
Ensembl chr12:41,267,549...41,270,042 		JBrowse link
G Zfp385a zinc finger protein 385A involved_in ISO (PMID:17719541) RGD PMID:17719541 NCBI chr 7:134,448,914...134,475,548
Ensembl chr 7:134,448,921...134,475,548 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car3 carbonic anhydrase 3 IMP RGD PMID:29559661 RGD:408427357 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:24947010) RGD PMID:24947010 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO
IMP		 (PMID:17579517) RGD PMID:17579517 PMID:17579517 RGD:8693356 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q99497 (PMID:24947010)		 Ensembl
RGD		 PMID:24947010 GO_REF:0000107 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
G Trap1 TNF receptor-associated protein 1 involved_in IMP PMID:17579517 ParkinsonsUK-UCL PMID:17579517 RGD:8693356 NCBI chr10:11,464,882...11,498,931
Ensembl chr10:11,464,821...11,498,981 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:22711822) RGD PMID:22711822 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355 		JBrowse link
G Bdkrb2 bradykinin receptor B2 acts_upstream_of_or_within ISO MGI:1857135 (PMID:16571598) RGD PMID:16571598 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497 		JBrowse link
G Epo erythropoietin involved_in ISO (PMID:14569084) RGD PMID:14569084 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Ptger2 prostaglandin E receptor 2 involved_in ISO (PMID:21716255) RGD PMID:21716255 NCBI chr15:18,215,013...18,228,714
Ensembl chr15:18,217,285...18,228,714 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 involved_in ISO (PMID:21716255) RGD PMID:21716255 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ybx3 Y box binding protein 3 involved_in IEA
ISO		 GO_REF:0000107
(PMID:22711822)		 Ensembl
RGD		 PMID:22711822 GO_REF:0000107 NCBI chr 4:165,129,747...165,153,101
Ensembl chr 4:165,129,758...165,153,161 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb2 bradykinin receptor B2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:98834|MGI:99702 (PMID:16571598)		 Ensembl
RGD		 PMID:16571598 GO_REF:0000107 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497 		JBrowse link
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa2 acetyl-CoA acyltransferase 2 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:18371312)		 Ensembl
UniProt
RGD		 PMID:18371312 GO_REF:0000024 GO_REF:0000107 NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in ISO (PMID:15901672) RGD PMID:15901672 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in ISO (PMID:15901672), (PMID:9393856)
GO_REF:0000114		 RGD
ComplexPortal		 PMID:9393856 PMID:15901672 GO_REF:0000114 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISO (PMID:27098698) RGD PMID:27098698 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within ISO MGI:104995 (PMID:15288121) RGD PMID:15288121 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:20625543) RGD PMID:20625543 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:20625543) RGD PMID:20625543 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within ISO (PMID:19096392) RGD PMID:19096392 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583 		JBrowse link
G Mpv17l MPV17 mitochondrial inner membrane protein like involved_in ISO (PMID:22306510) RGD PMID:22306510 NCBI chr10:1,988,451...2,025,300
Ensembl chr10:1,988,136...2,007,649 		JBrowse link
G Slc25a31 solute carrier family 25 member 31 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:123,695,387...123,711,275
Ensembl chr 2:123,695,408...123,710,795 		JBrowse link
G Slc25a4 solute carrier family 25 member 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733 		JBrowse link
G Slc25a5 solute carrier family 25 member 5 involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:19154410)		 UniProt
GO_Central
RGD		 PMID:19154410 GO_REF:0000024 GO_REF:0000033 NCBI chr  X:116,031,896...116,034,963
Ensembl chr  X:116,031,803...116,034,967 		JBrowse link
G Slc35f6 solute carrier family 35, member F6 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19154410)		 UniProt
RGD		 PMID:19154410 GO_REF:0000024 NCBI chr 6:25,725,822...25,737,720
Ensembl chr 6:25,725,819...25,737,730 		JBrowse link
G Tmem14a transmembrane protein 14A involved_in ISO (PMID:21723035) RGD PMID:21723035 NCBI chr 9:23,640,594...23,652,379
Ensembl chr 9:23,733,039...23,734,463
Ensembl chr 9:23,733,039...23,734,463 		JBrowse link
negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 involved_in ISO (PMID:14752510) RGD PMID:14752510 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:14752510) RGD PMID:14752510 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag5 BAG cochaperone 5 involved_in ISO (PMID:24475098) RGD PMID:24475098 NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in IMP PMID:27525436 ARUK-UCL PMID:27525436 RGD:13601987 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Gata4 GATA binding protein 4 acts_upstream_of ISO (PMID:25590961) RGD PMID:25590961 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2158814 (PMID:16373599)		 Ensembl
RGD		 PMID:16373599 GO_REF:0000107 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:15731106)		 Ensembl
RGD		 PMID:15731106 GO_REF:0000107 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Mapk7 mitogen-activated protein kinase 7 involved_in ISO
IEA		 (PMID:23043106)
GO_REF:0000107		 RGD
Ensembl		 PMID:23043106 GO_REF:0000107 NCBI chr10:46,170,264...46,176,262
Ensembl chr10:46,170,167...46,176,267 		JBrowse link
G Mir29b1 microRNA 29b-1 involved_in ISO (PMID:19956414) RGD PMID:19956414 NCBI chr 4:59,650,987...59,651,067
Ensembl chr 4:59,650,986...59,651,067 		JBrowse link
G Mir29b2 microRNA 29b-2 involved_in ISO (PMID:19956414) RGD PMID:19956414 NCBI chr13:106,570,371...106,570,451
Ensembl chr13:106,570,367...106,570,456 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 involved_in ISO (PMID:23043106) RGD PMID:23043106 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nme5 NME/NM23 family member 5 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:12788088)		 GO_Central
RGD		 PMID:12788088 GO_REF:0000033 NCBI chr18:26,163,558...26,180,742
Ensembl chr18:26,163,555...26,180,794 		JBrowse link
G Nol3 nucleolar protein 3 involved_in ISO
IEA		 (PMID:15004034)
GO_REF:0000107		 RGD
Ensembl		 PMID:15004034 GO_REF:0000107 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250 		JBrowse link
G Park7 Parkinsonism associated deglycase acts_upstream_of ISO (PMID:22523093) RGD PMID:22523093 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Ppia peptidylprolyl isomerase A involved_in ISO
ISS		 (PMID:26095851)
GO_REF:0000024		 RGD
UniProt		 PMID:26095851 GO_REF:0000024 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601 		JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr14:21,006,522...21,007,284
Ensembl chr14:21,006,538...21,007,310 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA		 (PMID:17317627)
GO_REF:0000107		 RGD
Ensembl		 PMID:17317627 GO_REF:0000107 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sod2 superoxide dismutase 2 involved_in ISO (PMID:12551919) RGD PMID:12551919 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 involved_in IMP
ISO		 PMID:23392669
UniProtKB:Q9ES19 (PMID:23392669)		 RGD PMID:23392669 PMID:23392669 RGD:10047168 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Cpe carboxypeptidase E IMP RGD PMID:25426952 RGD:405650601 NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21752258)		 Ensembl
RGD		 PMID:21752258 GO_REF:0000107 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Fbxo7 F-box protein 7 acts_upstream_of
involved_in		 ISO (PMID:26310625)
(PMID:25029497)		 RGD PMID:25029497 PMID:26310625 NCBI chr 7:17,809,224...17,837,549
Ensembl chr 7:17,809,231...17,837,530 		JBrowse link
G Fgf2 fibroblast growth factor 2 IMP RGD PMID:25426952 RGD:405650601 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fzd1 frizzled class receptor 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21752258)		 Ensembl
RGD		 PMID:21752258 GO_REF:0000107 NCBI chr 4:29,310,303...29,314,701
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in ISO
IEA		 (PMID:24899725)
GO_REF:0000107		 RGD
Ensembl		 PMID:24899725 GO_REF:0000107 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Il10 interleukin 10 involved_in ISO ComplexPortal:CPX-1134 (PMID:21857966) RGD PMID:21857966 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Nono non-POU domain containing, octamer-binding involved_in ISO (PMID:15790595) RGD PMID:15790595 NCBI chr  X:66,554,131...66,571,992
Ensembl chr  X:66,554,098...66,571,952 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISS
ISO		 GO_REF:0000024
(PMID:24899725)
(PMID:15790595), (PMID:16632486), (PMID:23743200)		 ParkinsonsUK-UCL
RGD		 PMID:15790595 PMID:16632486 PMID:23743200 PMID:24899725 GO_REF:0000024 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:16632486) RGD PMID:16632486 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA
IGI
ISS		 (PMID:17314283)
(PMID:23858059)
GO_REF:0000107
PMID:23392669
GO_REF:0000024		 RGD
Ensembl
ParkinsonsUK-UCL		 PMID:17314283 PMID:23858059 PMID:23392669 GO_REF:0000024 GO_REF:0000107, RGD:10047168 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 involved_in ISO (PMID:23743200) RGD PMID:23743200 NCBI chr10:105,917,732...105,922,658
Ensembl chr10:105,917,680...105,922,549 		JBrowse link
G Wnt1 Wnt family member 1 involved_in ISO (PMID:21752258) RGD PMID:21752258 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651 		JBrowse link
negative regulation of release of cytochrome c from mitochondria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:18977203)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:18977203 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Arrb2 arrestin, beta 2 IMP RGD PMID:19171933 RGD:5510006 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in ISO (PMID:15901672) RGD PMID:15901672 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in ISO (PMID:15901672), (PMID:9393856)
GO_REF:0000114		 RGD
ComplexPortal		 PMID:9393856 PMID:15901672 GO_REF:0000114 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bcl2l2 Bcl2-like 2 IDA RGD PMID:10724126 RGD:14394498 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624 		JBrowse link
G Fxn frataxin involved_in IEA
ISO		 GO_REF:0000107
(PMID:16608849)		 Ensembl
RGD		 PMID:16608849 GO_REF:0000107 NCBI chr 1:221,874,007...221,897,543
Ensembl chr 1:221,872,420...221,897,540 		JBrowse link
G Ghitm growth hormone inducible transmembrane protein involved_in ISO (PMID:18417609) RGD PMID:18417609 NCBI chr16:12,885,551...12,897,887
Ensembl chr16:12,885,553...12,897,879 		JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in ISO
IEA		 (PMID:12221075)
GO_REF:0000107		 RGD
Ensembl		 PMID:12221075 GO_REF:0000107 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Hgf hepatocyte growth factor involved_in ISO
IEA		 (PMID:20655899)
GO_REF:0000107		 RGD
Ensembl		 PMID:20655899 GO_REF:0000107 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A acts_upstream_of_or_within ISO (PMID:21856340) RGD PMID:21856340 NCBI chr 8:121,514,152...121,523,382
Ensembl chr 8:121,514,156...121,523,443 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B IMP RGD PMID:16397188 RGD:1626654 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:18977203)		 UniProt
RGD		 PMID:18977203 GO_REF:0000024 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Lmna lamin A/C involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:21151901)		 Ensembl
RGD		 PMID:21151901 GO_REF:0000107 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423 		JBrowse link
G Mfn2 mitofusin 2 IMP RGD PMID:18006463 RGD:12738362 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Nol3 nucleolar protein 3 involved_in IDA
IBA
IEA
ISO		 PMID:10590251
GO_REF:0000033
GO_REF:0000107
(PMID:15004034)		 GO_Central
Ensembl
RGD		 PMID:15004034 PMID:10590251 GO_REF:0000033 GO_REF:0000107, RGD:10047155 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:16839884)
GO_REF:0000107
(PMID:21149567)		 ParkinsonsUK-UCL
RGD
Ensembl		 PMID:16839884 PMID:21149567 GO_REF:0000024 GO_REF:0000107 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109 		JBrowse link
G Pam16 presequence translocase associated motor 16 IDA RGD PMID:24069394 RGD:13462066 NCBI chr10:10,942,534...10,950,654
Ensembl chr10:10,943,001...10,950,649 		JBrowse link
G Parl presenilin associated, rhomboid-like involved_in ISS
ISO		 GO_REF:0000024
(PMID:16839884)		 ParkinsonsUK-UCL
RGD		 PMID:16839884 GO_REF:0000024 NCBI chr11:80,594,059...80,620,506
Ensembl chr11:80,593,192...80,620,506 		JBrowse link
G Ppif peptidylprolyl isomerase F involved_in ISS
ISO		 GO_REF:0000024
(PMID:19228691)		 UniProt
RGD		 PMID:19228691 GO_REF:0000024 NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913 		JBrowse link
G Prelid1 PRELI domain containing 1 involved_in ISO (PMID:23931759) RGD PMID:23931759 NCBI chr17:9,305,349...9,308,389
Ensembl chr17:9,305,361...9,308,407 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA
ISS		 (PMID:19880420), (PMID:23453807)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
ParkinsonsUK-UCL		 PMID:19880420 PMID:23453807 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 involved_in ISO
IEA
ISS		 (PMID:19729910)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:19729910 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:104,656,809...104,665,122
Ensembl chr  X:104,656,812...104,665,097 		JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 involved_in ISO (PMID:23931759) RGD PMID:23931759 NCBI chr12:41,267,534...41,270,053
Ensembl chr12:41,267,549...41,270,042 		JBrowse link
negative regulation of TRAIL-activated apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir221 microRNA 221 involved_in ISO (PMID:18246122) RGD PMID:18246122 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573 		JBrowse link
G Mir222 microRNA 222 involved_in ISO (PMID:18246122) RGD PMID:18246122 NCBI chr  X:3,428,904...3,429,006
Ensembl chr  X:3,428,904...3,429,006 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISS
ISO		 GO_REF:0000024
(PMID:21785459)		 ParkinsonsUK-UCL
RGD		 PMID:21785459 GO_REF:0000024 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
positive regulation of apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07025928.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 4:51,682,224...51,682,961 JBrowse link
G Adora2a adenosine A2a receptor acts_upstream_of_or_within ISO MGI:2155985 (PMID:10845921) RGD PMID:10845921 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type IMP RGD PMID:15105833 RGD:2313858 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 acts_upstream_of_or_within ISO MGI:1889507 (PMID:16183742) RGD PMID:16183742 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Bid BH3 interacting domain death agonist acts_upstream_of_or_within ISO (PMID:8918887) RGD PMID:8918887 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Bmf Bcl2 modifying factor acts_upstream_of_or_within ISO (PMID:11546872) RGD PMID:11546872 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta acts_upstream_of_or_within ISO (PMID:17367784) RGD PMID:17367784 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994 		JBrowse link
G Casp2 caspase 2 acts_upstream_of_or_within ISO MGI:1889507 (PMID:16183742) RGD PMID:16183742 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379 		JBrowse link
G Ccn2 cellular communication network factor 2 IMP RGD PMID:19625611 RGD:2314487 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1889507 (PMID:16183742)		 GO_Central
RGD		 PMID:16183742 GO_REF:0000033 NCBI chr 7:29,940,240...29,952,907
Ensembl chr 7:29,798,586...29,952,907 		JBrowse link
G Cts7 cathepsin 7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:3,388,299...3,424,664
Ensembl chr17:3,388,299...3,393,439 		JBrowse link
G Cts7l1 cathepsin 7 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:3,306,668...3,311,964
Ensembl chr17:3,307,748...3,311,679 		JBrowse link
G Cts7l2 cathepsin 7 like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:3,903,602...3,907,088
Ensembl chr17:3,903,602...3,906,568 		JBrowse link
G Cts8 cathepsin 8 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:3,468,710...3,480,881
Ensembl chr17:3,468,710...3,480,881 		JBrowse link
G Ctsc cathepsin C acts_upstream_of_or_within ISO MGI:107285 (PMID:20435891) RGD PMID:20435891 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387 		JBrowse link
G Ctsh cathepsin H involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:109553 (PMID:20435891)		 GO_Central
RGD		 PMID:20435891 GO_REF:0000033 NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824 		JBrowse link
G Ctsj cathepsin J involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:3,738,729...3,743,381
Ensembl chr17:3,738,729...3,743,377 		JBrowse link
G Ctsk cathepsin K involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550 		JBrowse link
G Ctsl cathepsin L involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548 		JBrowse link
G Ctsm cathepsin M involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:3,236,848...3,242,265
Ensembl chr17:3,236,859...3,242,265 		JBrowse link
G Ctsml1 cathepsin M like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:3,752,000...3,760,046
Ensembl chr17:3,752,000...3,760,046 		JBrowse link
G Ctsq cathepsin Q involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:3,627,996...3,633,564
Ensembl chr17:3,629,082...3,633,428 		JBrowse link
G Ctsql1 cathepsin Q like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:3,681,700...3,687,099
Ensembl chr17:3,681,717...3,687,099 		JBrowse link
G Ctsql2 cathepsin Q-like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:3,698,973...3,704,787
Ensembl chr17:3,698,918...3,704,685 		JBrowse link
G Ctsr cathepsin R involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:3,522,365...3,531,128
Ensembl chr17:3,522,365...3,531,121 		JBrowse link
G Ctsrl1 cathepsin R like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:3,561,144...3,566,649
Ensembl chr17:3,561,144...3,566,639 		JBrowse link
G Ctss cathepsin S involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19903888)		 UniProt
Ensembl
RGD		 PMID:19903888 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Daxx death-domain associated protein acts_upstream_of_or_within ISO MGI:104662 (PMID:10684855) RGD PMID:10684855 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843 		JBrowse link
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 acts_upstream_of_or_within ISO MGI:3574590 (PMID:15680327) RGD PMID:15680327 NCBI chr17:26,148,652...26,159,358
Ensembl chr17:26,148,633...26,215,720 		JBrowse link
G Fas Fas cell surface death receptor involved_in ISO (PMID:11096076) RGD PMID:11096076 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Hsf1 heat shock transcription factor 1 IMP RGD PMID:21192280 RGD:10403035 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Ifnb1 interferon beta 1 involved_in ISO (PMID:10918594), (PMID:11337497) RGD PMID:10918594 PMID:11337497 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Il19 interleukin 19 acts_upstream_of_or_within ISO (PMID:12370360) RGD PMID:12370360 NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473 		JBrowse link
G Inca1 inhibitor of CDK, cyclin A1 interacting protein 1 acts_upstream_of_or_within ISO UniProtKB:Q8WYH8 (PMID:21750715) RGD PMID:21750715 NCBI chr10:55,401,989...55,414,364
Ensembl chr10:55,401,982...55,414,114 		JBrowse link
G Ing5 inhibitor of growth family, member 5 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:2144284 (PMID:21750715)		 GO_Central
RGD		 PMID:21750715 GO_REF:0000033 NCBI chr 9:94,326,549...94,343,392
Ensembl chr 9:94,326,548...94,344,220 		JBrowse link
G Inhbb inhibin subunit beta B involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:98957 (PMID:20454446)		 Ensembl
RGD		 PMID:20454446 GO_REF:0000107 NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832 		JBrowse link
G Jak2 Janus kinase 2 acts_upstream_of_or_within ISO (PMID:15012602) RGD PMID:15012602 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit IMP RGD PMID:15105833 RGD:2313858 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Maged1 MAGE family member D1 acts_upstream_of_or_within ISO MGI:1929608 (PMID:17488777), (PMID:19268530) RGD PMID:17488777 PMID:19268530 NCBI chr  X:59,422,715...59,429,381
Ensembl chr  X:59,422,717...59,429,364 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 acts_upstream_of_or_within ISO MGI:1346862 (PMID:16458303) RGD PMID:16458303 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1346861 (PMID:16458303)		 Ensembl
RGD		 PMID:16458303 GO_REF:0000107 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mir449a microRNA 449a involved_in ISO (PMID:25487955) RGD PMID:25487955 NCBI chr 2:44,670,714...44,670,804
Ensembl chr 2:44,670,714...44,670,804 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor acts_upstream_of_or_within ISO MGI:2447604 (PMID:14517295) RGD PMID:14517295 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 acts_upstream_of_or_within ISO (PMID:20530871) RGD PMID:20530871 NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610 		JBrowse link
G Ngfr nerve growth factor receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:10764727)		 Ensembl
RGD		 PMID:10764727 GO_REF:0000107 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Nkx3-1 NK3 homeobox 1 involved_in ISO (PMID:20599703) RGD PMID:20599703 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441 		JBrowse link
G Osm oncostatin M acts_upstream_of_or_within ISO (PMID:15012602) RGD PMID:15012602 NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313 		JBrowse link
G Pdcd7 programmed cell death 7 acts_upstream_of_or_within ISO (PMID:10037816) RGD PMID:10037816 NCBI chr 8:65,862,606...65,877,333
Ensembl chr 8:65,862,387...65,877,333 		JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within ISO MGI:1197015 (PMID:10684855) RGD PMID:10684855 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO (PMID:18293083) RGD PMID:18293083 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Prkcd protein kinase C, delta involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:15731106)		 Ensembl
RGD		 PMID:15731106 GO_REF:0000107 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Pten phosphatase and tensin homolog acts_upstream_of_or_within ISO MGI:1857937 (PMID:9778245) RGD PMID:9778245 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Rps3 ribosomal protein S3 involved_in ISO
IBA		 (PMID:14988002)
GO_REF:0000033		 RGD
GO_Central		 PMID:14988002 GO_REF:0000033 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680 		JBrowse link
G Rps3l1 ribosomal protein S3 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:51,559,683...51,560,522
Ensembl chr 3:51,559,683...51,560,524 		JBrowse link
G Sp1 Sp1 transcription factor involved_in ISO (PMID:18293083) RGD PMID:18293083 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961 		JBrowse link
G Testin testin gene involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:3,824,222...3,859,385
Ensembl chr17:3,846,899...3,859,385 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO
IEA		 (PMID:18758450)
GO_REF:0000107		 RGD
Ensembl		 PMID:18758450 GO_REF:0000107 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
G Tp63 tumor protein p63 acts_upstream_of_or_within ISO (PMID:9774969) RGD PMID:9774969 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398 		JBrowse link
G Tp73 tumor protein p73 acts_upstream_of_or_within ISO PR:Q9QXE4-2 (PMID:16044147) RGD PMID:16044147 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
G Tpd52l1 TPD52 like 1 involved_in ISO
IBA		 (PMID:14761963)
GO_REF:0000033		 RGD
GO_Central		 PMID:14761963 GO_REF:0000033 NCBI chr 1:26,172,038...26,290,704
Ensembl chr 1:26,172,170...26,291,109 		JBrowse link
G Traf7 TNF receptor associated factor 7 involved_in ISO (PMID:15001576) RGD PMID:15001576 NCBI chr10:13,533,570...13,552,290
Ensembl chr10:13,533,570...13,552,203 		JBrowse link
G Trim39 tripartite motif-containing 39 involved_in ISO
IEA
IBA		 (PMID:19100260)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:19100260 GO_REF:0000033 GO_REF:0000107 NCBI chr20:2,003,320...2,017,175
Ensembl chr20:1,983,533...2,020,117 		JBrowse link
G Wnt5a Wnt family member 5A involved_in IEA
ISO		 GO_REF:0000107
(PMID:21857966)		 Ensembl
RGD		 PMID:21857966 GO_REF:0000107 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
ISO		 GO_REF:0000024
(PMID:26015568), (PMID:26949185)		 UniProt
RGD		 PMID:26015568 PMID:26949185 GO_REF:0000024 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO MGI:1913418 (PMID:22240901) RGD PMID:22240901 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO
IBA		 (PMID:14676213)
GO_REF:0000033
UniProtKB:O55033 (PMID:16835242)		 RGD
GO_Central		 PMID:14676213 PMID:16835242 GO_REF:0000033 NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300 		JBrowse link
G Nck2 NCK adaptor protein 2 involved_in ISO
IBA		 UniProtKB:Q99M51 (PMID:16835242)
GO_REF:0000033		 RGD
GO_Central		 PMID:16835242 GO_REF:0000033 NCBI chr 9:45,713,979...45,840,330
Ensembl chr 9:45,714,883...45,840,307 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21216966)		 Ensembl
RGD		 PMID:21216966 GO_REF:0000107 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
G Rnf183 ring finger protein 183 involved_in ISO
IBA		 (PMID:29507230)
GO_REF:0000033		 RGD
GO_Central		 PMID:29507230 GO_REF:0000033 NCBI chr 5:75,877,111...75,886,253
Ensembl chr 5:75,876,003...75,886,191 		JBrowse link
G Serinc3 serine incorporator 3 acts_upstream_of_or_within ISO (PMID:12486168) RGD PMID:12486168 NCBI chr 3:152,301,882...152,321,327
Ensembl chr 3:152,301,772...152,321,808 		JBrowse link
G Sirt1 sirtuin 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:20955178)		 Ensembl
RGD		 PMID:20955178 GO_REF:0000107 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Spop speckle type BTB/POZ protein acts_upstream_of_or_within ISO MGI:102851 (PMID:20811152) RGD PMID:20811152 NCBI chr10:80,358,121...80,438,983
Ensembl chr10:80,358,124...80,483,955 		JBrowse link
positive regulation of extrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen involved_in ISO
IEA		 (PMID:10406457)
GO_REF:0000107		 RGD
Ensembl		 PMID:10406457 GO_REF:0000107 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 involved_in ISO (PMID:10406457) RGD PMID:10406457 NCBI chr  X:112,119,876...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
G App amyloid beta precursor protein involved_in ISO UniProtKB:Q9EPW9|UniProtKB:Q9QUK6 (PMID:20037584) RGD PMID:20037584 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Bcl10 BCL10, immune signaling adaptor involved_in
acts_upstream_of_or_within		 ISO
IBA
ISS		 (PMID:11466612)
(PMID:10753917)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:10753917 PMID:11466612 GO_REF:0000024 GO_REF:0000033 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523 		JBrowse link
G Bcl2l14 Bcl2-like 14 involved_in ISO (PMID:11054413) RGD PMID:11054413 NCBI chr 4:167,217,561...167,258,723
Ensembl chr 4:167,219,871...167,258,086 		JBrowse link
G Bid BH3 interacting domain death agonist involved_in ISO
IBA
IEA		 (PMID:21459798)
GO_REF:0000033
GO_REF:0000104		 RGD
GO_Central
UniProt		 PMID:21459798 GO_REF:0000033 GO_REF:0000104 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Casp8 caspase 8 acts_upstream_of_or_within ISO MGI:1889507 (PMID:16183742) RGD PMID:16183742 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cav1 caveolin 1 involved_in ISO
IEA		 (PMID:21382479)
GO_REF:0000107		 RGD
Ensembl		 PMID:21382479 GO_REF:0000107 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cd40lg CD40 ligand involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase involved_in ISO
IBA		 (PMID:21525013)
GO_REF:0000033		 RGD
GO_Central		 PMID:21525013 GO_REF:0000033 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658 		JBrowse link
G Dedd2 death effector domain containing 2 involved_in ISO (PMID:11741985) RGD PMID:11741985 NCBI chr 1:80,789,084...80,807,789
Ensembl chr 1:80,792,000...80,807,714 		JBrowse link
G Fadd Fas associated via death domain involved_in
acts_upstream_of_or_within		 ISO (PMID:21525013)
MGI:1336166|MGI:2154952 (PMID:22675671)		 RGD PMID:21525013 PMID:22675671 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Faslg Fas ligand involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G G0s2 G0/G1switch 2 involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:19706769)		 UniProt
GO_Central
RGD		 PMID:19706769 GO_REF:0000024 GO_REF:0000033 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in IDA PMID:23907461 UniProt PMID:23907461 RGD:8553942 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Hyal2 hyaluronidase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:19366691)		 Ensembl
RGD		 PMID:19366691 GO_REF:0000107 NCBI chr 8:108,241,895...108,246,853
Ensembl chr 8:108,243,133...108,246,850 		JBrowse link
G Itm2c integral membrane protein 2C involved_in ISO (PMID:14592447) RGD PMID:14592447 NCBI chr 9:86,545,927...86,559,745
Ensembl chr 9:86,545,921...86,559,742 		JBrowse link
G Lta lymphotoxin alpha involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859 		JBrowse link
G Ltb lymphotoxin beta involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381 		JBrowse link
G Ltbr lymphotoxin beta receptor involved_in ISO (PMID:20732415) RGD PMID:20732415 NCBI chr 4:158,108,884...158,115,339
Ensembl chr 4:158,108,886...158,121,539 		JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 involved_in ISO (PMID:19240112) RGD PMID:19240112 NCBI chr11:68,707,940...68,768,816
Ensembl chr11:68,707,969...68,768,816 		JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:15858817)		 Ensembl
RGD		 PMID:15858817 GO_REF:0000107 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236 		JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (PMID:21803845) RGD PMID:21803845 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha IMP RGD PMID:18322138 RGD:8693423 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:1857277 (PMID:8666928) RGD PMID:8666928 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:16964285) RGD PMID:16964285 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:5000222 (PMID:19136968)		 Ensembl
RGD		 PMID:19136968 GO_REF:0000107 NCBI chr 3:140,789,079...140,806,017
Ensembl chr 3:140,789,080...140,806,005 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:21525013), (PMID:22274400)
MGI:104798 (PMID:19498109)		 RGD PMID:19498109 PMID:21525013 PMID:22274400 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
G Runx3 RUNX family transcription factor 3 acts_upstream_of_or_within ISO MGI:2179229 (PMID:11955451) RGD PMID:11955451 NCBI chr 5:147,360,587...147,419,161
Ensembl chr 5:147,360,994...147,419,156 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 acts_upstream_of_or_within ISO MGI:3045799 (PMID:14976225) RGD PMID:14976225 NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
G Siglec1 sialic acid binding Ig like lectin 1 acts_upstream_of_or_within ISO MGI:3617694 (PMID:23408841) RGD PMID:23408841 NCBI chr 3:118,287,988...118,307,125
Ensembl chr 3:118,287,988...118,306,850 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P05067-PRO_0000000092 (PMID:20037584)		 Ensembl
RGD		 PMID:20037584 GO_REF:0000107 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO UniProtKB:P05067-PRO_0000000092 (PMID:20037584) RGD PMID:20037584 NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685 		JBrowse link
G Tnf tumor necrosis factor involved_in IMP
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:12131680 GO_REF:0000033, RGD:14995454 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A involved_in ISO
IBA		 (PMID:21525013)
GO_REF:0000033		 RGD
GO_Central		 PMID:21525013 GO_REF:0000033 NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045 		JBrowse link
G Tnfsf10 TNF superfamily member 10 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:20097879), (PMID:21525171), (PMID:22266862)
GO_REF:0000033
(PMID:15632112)		 RGD
GO_Central		 PMID:15632112 PMID:20097879 PMID:21525171 PMID:22266862 GO_REF:0000033 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tnfsf11 TNF superfamily member 11 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tnfsf12 TNF superfamily member 12 involved_in ISO (PMID:21525013) RGD PMID:21525013 NCBI chr10:54,403,870...54,413,213
Ensembl chr10:54,403,870...54,413,213 		JBrowse link
G Tnfsf14 TNF superfamily member 14 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:2,068,295...2,073,128
Ensembl chr 9:2,069,104...2,073,216 		JBrowse link
G Tnfsf15 TNF superfamily member 15 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:77,134,885...77,156,171
Ensembl chr 5:77,139,878...77,156,228 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in ISO (PMID:21525013) RGD PMID:21525013 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
G Wdr35 WD repeat domain 35 IMP RGD PMID:20193664 RGD:11553917 NCBI chr 6:31,771,315...31,831,450
Ensembl chr 6:31,771,360...31,831,029 		JBrowse link
G Wwox WW domain-containing oxidoreductase involved_in ISO (PMID:19366691) RGD PMID:19366691 NCBI chr19:42,432,141...43,360,278
Ensembl chr19:42,432,152...43,359,391 		JBrowse link
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnna1 catenin alpha 1 acts_upstream_of_or_within ISO MGI:2677796 (PMID:22411810) RGD PMID:22411810 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910 		JBrowse link
G Dapk3 death-associated protein kinase 3 involved_in IMP PMID:21172653 UniProt PMID:21172653 RGD:8554227 NCBI chr 7:8,524,182...8,532,552
Ensembl chr 7:8,524,183...8,532,558 		JBrowse link
G Htra2 HtrA serine peptidase 2 involved_in ISO (PMID:20125124) RGD PMID:20125124 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095 		JBrowse link
G Inhba inhibin subunit beta A involved_in ISO
ISS		 (PMID:8267637)
GO_REF:0000024		 RGD
UniProt		 PMID:8267637 GO_REF:0000024 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Jak3 Janus kinase 3 involved_in ISO (PMID:16020505) RGD PMID:16020505 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857478 (PMID:15039234)		 Ensembl
RGD		 PMID:15039234 GO_REF:0000107 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha acts_upstream_of_or_within ISO (PMID:12115603) RGD PMID:12115603 NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327 		JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha acts_upstream_of_or_within ISO (PMID:12944463) RGD PMID:12944463 NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129 		JBrowse link
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta involved_in ISO
IEA		 (PMID:21172653)
GO_REF:0000107		 RGD
Ensembl		 PMID:21172653 GO_REF:0000107 NCBI chr 8:51,195,860...51,228,442
Ensembl chr 8:51,186,717...51,228,485 		JBrowse link
G Ret ret proto-oncogene involved_in ISO (PMID:10921886) RGD PMID:10921886 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176 		JBrowse link
G Srpx sushi-repeat-containing protein, X-linked acts_upstream_of_or_within ISO MGI:3706175 (PMID:17088259) RGD PMID:17088259 NCBI chr  X:12,676,984...12,751,296
Ensembl chr  X:12,566,645...12,747,882 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 acts_upstream_of_or_within ISO (PMID:8206089) RGD PMID:8206089 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Unc5b unc-5 netrin receptor B involved_in IMP PMID:21172653 UniProt PMID:21172653 RGD:8554227 NCBI chr20:28,697,726...28,764,474
Ensembl chr20:28,697,726...28,764,537 		JBrowse link
G Wwox WW domain-containing oxidoreductase acts_upstream_of_or_within ISO (PMID:19366691) RGD PMID:19366691 NCBI chr19:42,432,141...43,360,278
Ensembl chr19:42,432,152...43,359,391 		JBrowse link
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1b bone morphogenetic protein receptor type 1B acts_upstream_of_or_within ISO MGI:1927616|MGI:95484 (PMID:18363966) RGD PMID:18363966 NCBI chr 2:230,538,252...230,871,077
Ensembl chr 2:230,541,558...230,871,368 		JBrowse link
G Faf1 Fas associated factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:8524870)		 Ensembl
RGD		 PMID:8524870 GO_REF:0000107 NCBI chr 5:124,426,032...124,790,014
Ensembl chr 5:124,426,062...124,789,977 		JBrowse link
G Mal mal, T-cell differentiation protein acts_upstream_of_or_within ISO (PMID:12776198) RGD PMID:12776198 NCBI chr 3:114,864,378...114,888,136
Ensembl chr 3:114,864,378...114,888,136 		JBrowse link
G Pea15 proliferation and apoptosis adaptor protein 15 acts_upstream_of_or_within ISO (PMID:10588860) RGD PMID:10588860 NCBI chr13:84,657,815...84,667,437
Ensembl chr13:84,654,870...84,667,499 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:15705586) RGD PMID:15705586 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO (PMID:8940094) RGD PMID:8940094 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in ISO
IEA		 (PMID:9391078)
GO_REF:0000107		 RGD
Ensembl		 PMID:9391078 GO_REF:0000107 NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
G Skil SKI-like proto-oncogene acts_upstream_of_or_within ISO MGI:2387096 (PMID:10811619) RGD PMID:10811619 NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080 		JBrowse link
G Stk3 serine/threonine kinase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:104798|MGI:1928487|MGI:1929004 (PMID:20080598)		 Ensembl
RGD		 PMID:20080598 GO_REF:0000107 NCBI chr 7:66,053,209...66,323,292
Ensembl chr 7:66,052,345...66,323,233 		JBrowse link
G Stk4 serine/threonine kinase 4 acts_upstream_of_or_within ISO MGI:104798|MGI:1928487 (PMID:20080598) RGD PMID:20080598 NCBI chr 3:152,745,958...152,827,747
Ensembl chr 3:152,745,681...152,827,744 		JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:18726995) RGD PMID:18726995 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Trps1 transcriptional repressor GATA binding 1 acts_upstream_of_or_within ISO MGI:107191|MGI:95484 (PMID:18363966) RGD PMID:18363966 NCBI chr 7:81,916,668...82,142,733
Ensembl chr 7:81,921,601...82,141,905 		JBrowse link
G Zswim2 zinc finger, SWIM-type containing 2 acts_upstream_of_or_within ISO (PMID:16522193) RGD PMID:16522193 NCBI chr 3:68,993,422...69,015,441
Ensembl chr 3:68,995,027...69,015,411 		JBrowse link
positive regulation of intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 IDA MMO:0000679 RGD PMID:23729662 RGD:329403056 NCBI chr13:77,747,752...77,833,952
Ensembl chr13:77,768,468...77,833,951 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:2158306 (PMID:14502238)
(PMID:14963330), (PMID:21199865), (PMID:21262771)		 UniProt
RGD		 PMID:14502238 PMID:14963330 PMID:21199865 PMID:21262771 GO_REF:0000024 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 involved_in IMP
IEA
ISO
ISS		 PMID:27031958
GO_REF:0000107
(PMID:17289999), (PMID:27031958)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:17289999 PMID:27031958 PMID:27031958 GO_REF:0000024 GO_REF:0000107, RGD:14390051 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bcap31 B-cell receptor-associated protein 31 involved_in ISO (PMID:21183955) RGD PMID:21183955 NCBI chr  X:151,397,567...151,429,666
Ensembl chr  X:151,397,576...151,428,506 		JBrowse link
G Bcl2l11 Bcl2-like 11 involved_in ISO (PMID:21671007) RGD PMID:21671007 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 involved_in ISO (PMID:17938203) RGD PMID:17938203 NCBI chr 1:15,088,436...15,117,666
Ensembl chr 1:15,070,894...15,148,832 		JBrowse link
G Becn1 beclin 1 involved_in IMP
ISO
ISS		 PMID:27031958
(PMID:27031958)
GO_REF:0000024		 RGD
UniProt		 PMID:27031958 PMID:27031958 GO_REF:0000024, RGD:14390051 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bid BH3 interacting domain death agonist involved_in ISO
IBA
IEA		 (PMID:21262771)
GO_REF:0000033
GO_REF:0000104		 RGD
GO_Central
UniProt		 PMID:21262771 GO_REF:0000033 GO_REF:0000104 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
ISO		 GO_REF:0000024
(PMID:23429263)		 UniProt
RGD		 PMID:23429263 GO_REF:0000024 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase acts_upstream_of_or_within ISO MGI:3793294 (PMID:17938250) RGD PMID:17938250 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650 		JBrowse link
G Cav1 caveolin 1 involved_in ISO
IEA		 (PMID:21382479)
GO_REF:0000107		 RGD
Ensembl		 PMID:21382479 GO_REF:0000107 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Clu clusterin involved_in ISS
ISO		 GO_REF:0000024
(PMID:21567405)		 UniProt
RGD		 PMID:21567405 GO_REF:0000024 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Cyct cytochrome c, testis acts_upstream_of_or_within ISO (PMID:16757556) RGD PMID:16757556 NCBI chr 3:61,290,090...61,297,158
Ensembl chr 3:60,913,562...61,297,158 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:27031958)		 UniProt
Ensembl
RGD		 PMID:27031958 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Ei24 EI24, autophagy associated transmembrane protein acts_upstream_of_or_within ISO (PMID:17981155) RGD PMID:17981155 NCBI chr 8:36,494,289...36,510,653
Ensembl chr 8:36,494,289...36,510,571 		JBrowse link
G Fis1 fission, mitochondrial 1 involved_in ISO
IEA		 (PMID:21183955)
GO_REF:0000107		 RGD
Ensembl		 PMID:21183955 GO_REF:0000107 NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377 		JBrowse link
G Flcn folliculin acts_upstream_of_or_within ISO MGI:4348628 (PMID:21258407) RGD PMID:21258407 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769 		JBrowse link
G Gsdme gasdermin E involved_in ISO (PMID:21522185) RGD PMID:21522185 NCBI chr 4:79,258,799...79,321,129
Ensembl chr 4:79,257,804...79,320,806 		JBrowse link
G Il19 interleukin 19 acts_upstream_of_or_within ISO MGI:3605069 (PMID:23468852) RGD PMID:23468852 NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473 		JBrowse link
G Il20ra interleukin 20 receptor subunit alpha acts_upstream_of_or_within ISO MGI:1890472 (PMID:23468852) RGD PMID:23468852 NCBI chr 1:14,424,215...14,494,226
Ensembl chr 1:14,451,228...14,493,602 		JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase involved_in ISO
IEA		 (PMID:16116473)
GO_REF:0000107		 RGD
Ensembl		 PMID:16116473 GO_REF:0000107 NCBI chr 5:141,888,318...141,916,945
Ensembl chr 5:141,888,326...141,903,794 		JBrowse link
G Mir16 microRNA 16 involved_in ISO RNAcentral:URS00003D1AE3_9606 (PMID:16166262) RGD PMID:16166262 NCBI chr 2:153,245,349...153,245,443
Ensembl chr 2:153,245,349...153,245,443 		JBrowse link
G Mir27b microRNA 27b acts_upstream_of_or_within ISO UniProtKB:P01375 (PMID:31124343) RGD PMID:31124343 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529 		JBrowse link
G Nherf1 NHERF family PDZ scaffold protein 1 involved_in ISO (PMID:20012548) RGD PMID:20012548 NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598 		JBrowse link
G Nkx3-1 NK3 homeobox 1 involved_in ISO (PMID:17486276) RGD PMID:17486276 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator involved_in ISO
ISS
IMP		 (PMID:27031958)
GO_REF:0000024		 RGD
UniProt		 PMID:27031958 PMID:27031958 GO_REF:0000024, RGD:14390051 NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281 		JBrowse link
G Pawr pro-apoptotic WT1 regulator IMP RGD PMID:10349840 RGD:9835366 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028 		JBrowse link
G Plagl2 PLAG1 like zinc finger 2 acts_upstream_of_or_within ISO (PMID:11832486) RGD PMID:11832486 NCBI chr 3:141,695,322...141,708,516
Ensembl chr 3:141,695,322...141,708,503 		JBrowse link
G Plekhf1 pleckstrin homology and FYVE domain containing 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:90,908,304...90,915,862
Ensembl chr 1:90,904,742...90,915,820 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:21454712) RGD PMID:21454712 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Prkra protein activator of interferon induced protein kinase EIF2AK2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:12181197)		 Ensembl
RGD		 PMID:12181197 GO_REF:0000107 NCBI chr 3:61,575,447...61,594,393
Ensembl chr 3:61,575,447...61,594,347 		JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in ISO (PMID:19767770) RGD PMID:19767770 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 acts_upstream_of_or_within ISO (PMID:10490590) RGD PMID:10490590 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121 		JBrowse link
G S100a8 S100 calcium binding protein A8 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19935772)		 UniProt
RGD		 PMID:19935772 GO_REF:0000024 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643 		JBrowse link
G S100a9 S100 calcium binding protein A9 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:19935772)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:19935772 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Septin4 septin 4 involved_in ISO (PMID:21185211) RGD PMID:21185211 NCBI chr10:72,366,729...72,390,764
Ensembl chr10:72,366,873...72,390,768 		JBrowse link
G Siah1 siah E3 ubiquitin protein ligase 1 involved_in ISO
IEA		 (PMID:21185211)
GO_REF:0000107		 RGD
Ensembl		 PMID:21185211 GO_REF:0000107 NCBI chr19:20,378,908...20,402,512
Ensembl chr19:20,378,439...20,403,808 		JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 involved_in ISO
IBA		 (PMID:21262771), (PMID:24709986)
GO_REF:0000033		 RGD
GO_Central		 PMID:21262771 PMID:24709986 GO_REF:0000033 NCBI chr12:20,907,410...20,940,232
Ensembl chr12:20,907,435...20,939,752 		JBrowse link
G Taf6 TATA-box binding protein associated factor 6 involved_in ISO (PMID:20096117) RGD PMID:20096117 NCBI chr12:17,055,864...17,064,244
Ensembl chr12:17,055,873...17,064,247 		JBrowse link
G Tp53 tumor protein p53 involved_in ISS
IEA
ISO
IMP		 GO_REF:0000024
GO_REF:0000107
(PMID:14963330), (PMID:27031958)		 UniProt
Ensembl
RGD		 PMID:14963330 PMID:27031958 PMID:27031958 GO_REF:0000024 GO_REF:0000107, RGD:14390051 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif5a eukaryotic translation initiation factor 5A involved_in ISO (PMID:15371445) RGD PMID:15371445 NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656 		JBrowse link
G Mir186 microRNA 186 acts_upstream_of ISO (PMID:27714074) RGD PMID:27714074 NCBI chr 2:246,582,806...246,582,891
Ensembl chr 2:246,582,806...246,582,891 		JBrowse link
G Msx1 msh homeobox 1 involved_in ISO (PMID:15705871) RGD PMID:15705871 NCBI chr14:72,961,036...72,964,970
Ensembl chr14:72,961,148...72,964,966 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO (PMID:10962037) RGD PMID:10962037 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Rps7 ribosomal protein S7 involved_in ISO (PMID:17310983) RGD PMID:17310983 NCBI chr 6:45,266,200...45,271,064
Ensembl chr 6:45,223,980...45,271,145
Ensembl chr 5:45,223,980...45,271,145 		JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 involved_in ISO (PMID:24523556) RGD PMID:24523556 NCBI chr 2:233,750,838...233,784,817
Ensembl chr 2:233,750,838...233,784,784 		JBrowse link
G Ubb ubiquitin B acts_upstream_of_or_within ISO (PMID:17571083) RGD PMID:17571083 NCBI chr10:47,247,630...47,249,335
Ensembl chr10:47,245,637...47,249,333 		JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbh1 F-box DNA helicase 1 acts_upstream_of_or_within ISO (PMID:23361013) RGD PMID:23361013 NCBI chr17:66,749,506...66,787,590
Ensembl chr17:66,749,534...66,787,590 		JBrowse link
G Mtch2 mitochondrial carrier 2 acts_upstream_of_or_within ISO MGI:2449949|MGI:5566664 (PMID:26219591) RGD PMID:26219591 NCBI chr 3:76,830,549...76,850,189
Ensembl chr 3:76,830,413...76,850,189 		JBrowse link
G Nacc2 NACC family member 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:22926524)		 Ensembl
RGD		 PMID:22926524 GO_REF:0000107 NCBI chr 3:8,879,952...8,946,660
Ensembl chr 3:8,883,065...8,946,660 		JBrowse link
G Pias4 protein inhibitor of activated STAT, 4 acts_upstream_of_or_within ISO (PMID:16816390) RGD PMID:16816390 NCBI chr 7:8,546,312...8,559,838
Ensembl chr 7:8,546,312...8,559,808 		JBrowse link
G Plscr1 phospholipid scramblase 1 acts_upstream_of_or_within ISO (PMID:12509439) RGD PMID:12509439 NCBI chr 8:92,784,279...92,804,698
Ensembl chr 8:92,784,356...92,804,692 		JBrowse link
G Rad9a RAD9 checkpoint clamp component A acts_upstream_of_or_within ISO MGI:2442925 (PMID:15983387) RGD PMID:15983387 NCBI chr 1:201,488,511...201,553,582
Ensembl chr 1:201,487,136...201,553,608 		JBrowse link
G Rps3 ribosomal protein S3 involved_in ISO (PMID:22510408) RGD PMID:22510408 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680 		JBrowse link
G Skil SKI-like proto-oncogene acts_upstream_of_or_within ISO MGI:2387096 (PMID:10811619) RGD PMID:10811619 NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080 		JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpl26 ribosomal protein L26 involved_in ISO
IEA		 (PMID:16213212)
GO_REF:0000107		 RGD
Ensembl		 PMID:16213212 GO_REF:0000107 NCBI chr10:53,610,836...53,613,966
Ensembl chr10:53,610,421...53,613,966 		JBrowse link
G Steap3 STEAP3 metalloreductase acts_upstream_of_or_within ISO MGI:4398911 (PMID:18617898) RGD PMID:18617898 NCBI chr13:31,351,954...31,397,344
Ensembl chr13:31,351,954...31,396,519 		JBrowse link
G Tp73 tumor protein p73 acts_upstream_of_or_within ISO MGI:2442925|MGI:98834 (PMID:15983387) RGD PMID:15983387 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death involved_in ISO
IEA		 (PMID:21716255)
GO_REF:0000107		 RGD
Ensembl		 PMID:21716255 GO_REF:0000107 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nox1 NADPH oxidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3616995 (PMID:19661248)		 Ensembl
RGD		 PMID:19661248 GO_REF:0000107 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Park7 Parkinsonism associated deglycase acts_upstream_of_or_within ISO (PMID:22555455) RGD PMID:22555455 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Sfpq splicing factor proline and glutamine rich involved_in ISO (PMID:15790595) RGD PMID:15790595 NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472 		JBrowse link
G Sod1 superoxide dismutase 1 involved_in ISO
IEA		 (PMID:12551919)
GO_REF:0000107		 RGD
Ensembl		 PMID:12551919 GO_REF:0000107 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Vnn1 vanin 1 involved_in ISO (PMID:15282320) RGD PMID:15282320 NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395 		JBrowse link
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 IMP RGD PMID:28386847 RGD:329337357 NCBI chr13:77,747,752...77,833,952
Ensembl chr13:77,768,468...77,833,951 		JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:23858059) RGD PMID:23858059 NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in ISO UniProtKB:Q9WVS6 (PMID:23858059) RGD PMID:23858059 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Mmp2 matrix metallopeptidase 2 IMP RGD PMID:27614125 RGD:329961568 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Ralbp1 ralA binding protein 1 IMP RGD PMID:23788031 RGD:12904719 NCBI chr 9:105,456,425...105,493,235
Ensembl chr 9:105,456,425...105,492,707 		JBrowse link
positive regulation of TRAIL-activated apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf3 activating transcription factor 3 involved_in ISO (PMID:24939851) RGD PMID:24939851 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISO (PMID:23000344) RGD PMID:23000344 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 involved_in ISO (PMID:24370996) RGD PMID:24370996 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in ISO (PMID:15147274) RGD PMID:15147274 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424 		JBrowse link
regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO ComplexPortal:CPX-1134 (PMID:23921129) RGD PMID:23921129 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Fcgr2b Fc gamma receptor 2B involved_in IMP
ISO		 PMID:23921129
(PMID:23921129)		 RGD PMID:23921129 PMID:23921129 RGD:12910988 NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778 		JBrowse link
regulation of extrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl5 acyl-CoA synthetase long-chain family member 5 involved_in ISO (PMID:17681178) RGD PMID:17681178 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607 		JBrowse link
G Dbh dopamine beta-hydroxylase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857556 (PMID:15849236)		 Ensembl
RGD		 PMID:15849236 GO_REF:0000107 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Deptor DEP domain containing MTOR-interacting protein involved_in ISO (PMID:19446321) RGD PMID:19446321 NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773 		JBrowse link
G Madd MAP-kinase activating death domain involved_in ISO (PMID:11577081) RGD PMID:11577081 NCBI chr 3:77,114,330...77,157,865
Ensembl chr 3:77,114,314...77,157,701 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO (PMID:7743522) RGD PMID:7743522 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Traf1 TNF receptor-associated factor 1 involved_in ISO (PMID:10692572) RGD PMID:10692572 NCBI chr 3:18,222,024...18,242,163
Ensembl chr 3:18,222,054...18,241,807 		JBrowse link
regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO MGI:2176216|MGI:2181474 (PMID:16207751), (PMID:18191119) RGD PMID:16207751 PMID:18191119 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
regulation of extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fem1b fem-1 homolog B involved_in ISO (PMID:10542291) RGD PMID:10542291 NCBI chr 8:63,265,301...63,278,577
Ensembl chr 8:63,265,301...63,278,577 		JBrowse link
G Lgals3 galectin 3 involved_in ISO
IEA		 (PMID:8692888)
GO_REF:0000107		 RGD
Ensembl		 PMID:8692888 GO_REF:0000107 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025 		JBrowse link
G Madd MAP-kinase activating death domain involved_in ISS
ISO		 GO_REF:0000024
(PMID:9115275)		 UniProt
RGD		 PMID:9115275 GO_REF:0000024 NCBI chr 3:77,114,330...77,157,865
Ensembl chr 3:77,114,314...77,157,701 		JBrowse link
G Sp100 SP100 nuclear antigen involved_in ISO (PMID:17245429) RGD PMID:17245429 NCBI chr 9:86,310,990...86,377,036
Ensembl chr 9:86,311,032...86,377,034 		JBrowse link
G Stx4 syntaxin 4 involved_in ISO (PMID:20956541) RGD PMID:20956541 NCBI chr 1:182,451,108...182,459,701
Ensembl chr 1:182,451,117...182,459,979 		JBrowse link
G Tmc8 transmembrane channel-like 8 involved_in ISO (PMID:23429285) RGD PMID:23429285 NCBI chr10:103,000,038...103,010,601
Ensembl chr10:102,998,402...103,010,590 		JBrowse link
regulation of intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyld CYLD lysine 63 deubiquitinase involved_in ISO
IBA		 (PMID:21525013)
GO_REF:0000033		 RGD
GO_Central		 PMID:21525013 GO_REF:0000033 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658 		JBrowse link
G Dapk2 death-associated protein kinase 2 involved_in ISO (PMID:10376525) RGD PMID:10376525 NCBI chr 8:66,706,536...66,825,567
Ensembl chr 8:66,706,609...66,825,567 		JBrowse link
G Ptpmt1 protein tyrosine phosphatase, mitochondrial 1 involved_in ISO
IEA		 UniProtKB:Q9Y6J8 (PMID:24709986)
GO_REF:0000107		 RGD
Ensembl		 PMID:24709986 GO_REF:0000107 NCBI chr 3:76,889,922...76,899,427
Ensembl chr 3:76,889,922...76,899,427 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:14730312) RGD PMID:14730312 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 involved_in ISO UniProtKB:Q8WUK0 (PMID:24709986) RGD PMID:24709986 NCBI chr12:20,907,410...20,940,232
Ensembl chr12:20,907,435...20,939,752 		JBrowse link
regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd2 ankyrin repeat domain 2 acts_upstream_of_or_within ISO (PMID:18302940) RGD PMID:18302940 NCBI chr 1:240,847,111...240,856,563
Ensembl chr 1:240,847,072...240,856,566 		JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:17571083)		 Ensembl
RGD		 PMID:17571083 GO_REF:0000107 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnrnpk heterogeneous nuclear ribonucleoprotein K acts_upstream_of_or_within ISO (PMID:20673990) RGD PMID:20673990 NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997 		JBrowse link
regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tifab TIFA inhibitor acts_upstream_of_or_within ISO (PMID:32101751) RGD PMID:32101751 NCBI chr17:8,433,406...8,436,541
Ensembl chr17:8,431,635...8,436,592 		JBrowse link
G Usp15 ubiquitin specific peptidase 15 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:32101751)		 Ensembl
RGD		 PMID:32101751 GO_REF:0000107 NCBI chr 7:58,756,714...58,848,778
Ensembl chr 7:58,756,872...58,848,721 		JBrowse link
regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P4hb prolyl 4-hydroxylase subunit beta involved_in ISO (PMID:12095988) RGD PMID:12095988 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500 		JBrowse link
G Ubqln1 ubiquilin 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:12095988)
GO_REF:0000107		 HGNC
RGD
Ensembl		 PMID:12095988 GO_REF:0000024 GO_REF:0000107 NCBI chr17:6,439,002...6,477,096
Ensembl chr17:6,439,002...6,477,090 		JBrowse link
regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:15983381) RGD PMID:15983381 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 IMP RGD PMID:17347665 RGD:10414071 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Prodh proline dehydrogenase involved_in ISO (PMID:23743200) RGD PMID:23743200 NCBI chr11:82,910,043...82,927,305
Ensembl chr11:82,910,137...82,927,305 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:30684126) RGD PMID:30684126 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      signal transduction 7183
        regulation of signal transduction 3282
          regulation of apoptotic signaling pathway 466
            negative regulation of apoptotic signaling pathway + 262
            positive regulation of apoptotic signaling pathway + 198
            regulation of extrinsic apoptotic signaling pathway + 181
            regulation of intrinsic apoptotic signaling pathway + 204
Path 2
Term Annotations click to browse term
  biological_process 20076
    biological regulation 13559
      regulation of biological process 13136
        regulation of cellular process 12773
          signal transduction 7183
            apoptotic signaling pathway 688
              regulation of apoptotic signaling pathway 466
                negative regulation of apoptotic signaling pathway + 262
                positive regulation of apoptotic signaling pathway + 198
                regulation of extrinsic apoptotic signaling pathway + 181
                regulation of intrinsic apoptotic signaling pathway + 204
paths to the root