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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of apoptotic signaling pathway
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Accession:GO:2001233 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of apoptotic signaling pathway.
Synonyms:exact_synonym: regulation of apoptotic signalling pathway


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regulation of apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp8 caspase 8 acts_upstream_of_or_within ISO MGI:103223 (MGI:3056854|PMID:15456877) RGD PMID:15456877 MGI:3056854 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Pmp22 peripheral myelin protein 22 acts_upstream_of_or_within ISO MGI:1856217 (MGI:5517729|PMID:23847051) RGD PMID:23847051 MGI:5517729 NCBI chr10:49,538,588...49,568,583
Ensembl chr10:49,538,588...49,568,583
JBrowse link
G Ppia peptidylprolyl isomerase A involved_in ISS
ISO
GO_REF:0000024
(PMID:23180369)
UniProt
RGD
PMID:23180369 GO_REF:0000024 NCBI chr14:86,673,775...86,677,443
Ensembl chr14:86,673,775...86,677,443
JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr14:22,706,906...22,707,648
Ensembl chr14:22,706,901...22,707,668
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor acts_upstream_of_or_within ISO MGI:1261423 (MGI:3056854|PMID:15456877) RGD PMID:15456877 MGI:3056854 NCBI chr 4:145,580,869...145,587,835
Ensembl chr 4:145,580,799...145,587,845
JBrowse link
negative regulation of apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aatf apoptosis antagonizing transcription factor acts_upstream_of_or_within ISO MGI:1930187 (MGI:4359364|PMID:17488777) RGD PMID:17488777 MGI:4359364 NCBI chr10:71,744,648...71,837,851
Ensembl chr10:71,744,659...71,837,851
JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in ISO
ISS
(PMID:15946935)
GO_REF:0000024
RGD
UniProt
PMID:15946935 GO_REF:0000024 NCBI chr 1:250,557,042...250,665,083
Ensembl chr 1:250,557,044...250,630,677
JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2675387 (MGI:3796786|PMID:18436203)
Ensembl
RGD
PMID:18436203 GO_REF:0000107 MGI:3796786 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in
acts_upstream_of_or_within
ISO (PMID:20097879)
(MGI:2158578|PMID:11546872)
RGD PMID:11546872 PMID:20097879 MGI:2158578 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bdnf brain-derived neurotrophic factor involved_in ISO RNAcentral:URS000055128B_10090 (MGI:6295053|PMID:26708520) RGD PMID:26708520 MGI:6295053 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Bmf Bcl2 modifying factor acts_upstream_of_or_within ISO (MGI:2158578|PMID:11546872) RGD PMID:11546872 MGI:2158578 NCBI chr 3:110,303,515...110,324,125
Ensembl chr 3:110,306,067...110,324,084
JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger acts_upstream_of_or_within ISO MGI:99161 (MGI:1932296|PMID:11290297) RGD PMID:11290297 MGI:1932296 NCBI chr17:85,360,439...85,370,283
Ensembl chr17:85,364,483...85,368,208
JBrowse link
G Cdk11b cyclin-dependent kinase 11B involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3043373 (MGI:3041915|PMID:15060143)
Ensembl
RGD
PMID:15060143 GO_REF:0000107 MGI:3041915 NCBI chr 5:173,051,900...173,078,049
Ensembl chr 5:173,052,063...173,078,046
JBrowse link
G Cth cystathionine gamma-lyase acts_upstream_of_or_within ISO (MGI:5304595|PMID:22244329) RGD PMID:22244329 MGI:5304595 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1858008|MGI:2148567|MGI:98957 (MGI:3051737|PMID:15131783), (MGI:4454604|PMID:20454446)
Ensembl
RGD
PMID:15131783 PMID:20454446 GO_REF:0000107 MGI:3051737 MGI:4454604 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in ISO UniProtKB:P35411 (PMID:10869418) RGD PMID:10869418 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in IGI PMID:10869418 ARUK-UCL PMID:10869418 RGD:4892026 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514
JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 acts_upstream_of_or_within ISO MGI:4888719 (MGI:4880811|PMID:21209208) RGD PMID:21209208 MGI:4880811 NCBI chr 7:141,158,769...141,185,781
Ensembl chr 7:141,157,963...141,185,710
JBrowse link
G Gata4 GATA binding protein 4 involved_in ISO (MGI:5780531|PMID:25590961) RGD PMID:25590961 MGI:5780531 NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965
JBrowse link
G Gnai2 G protein subunit alpha i2 IMP RGD PMID:25633408 RGD:13507311 NCBI chr 8:116,370,730...116,391,337
Ensembl chr 8:116,370,744...116,391,307
JBrowse link
G Gnai3 G protein subunit alpha i3 IMP RGD PMID:25633408 RGD:13507311 NCBI chr 2:210,896,779...210,934,733
Ensembl chr 2:210,896,656...210,934,749
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 acts_upstream_of_or_within ISO (MGI:3581090|PMID:15731106) RGD PMID:15731106 MGI:3581090 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 acts_upstream_of_or_within ISO (MGI:3688933|PMID:16857185) RGD PMID:16857185 MGI:3688933 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Igbp1 immunoglobulin binding protein 1 acts_upstream_of_or_within ISO MGI:2448686|MGI:3056510 (MGI:3056248|PMID:15499020) RGD PMID:15499020 MGI:3056248 NCBI chr  X:70,322,764...70,345,005
Ensembl chr  X:70,322,755...70,345,005
JBrowse link
G Ing2 inhibitor of growth family, member 2 acts_upstream_of_or_within ISO MGI:4879096 (MGI:4867787|PMID:21124965) RGD PMID:21124965 MGI:4867787 NCBI chr16:47,714,756...47,725,836
Ensembl chr16:47,717,951...47,725,836
JBrowse link
G Madd MAP-kinase activating death domain acts_upstream_of_or_within ISO (MGI:3700423|PMID:14735464) RGD PMID:14735464 MGI:3700423 NCBI chr 3:79,960,301...80,003,023
Ensembl chr 3:79,960,301...80,003,032
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 acts_upstream_of_or_within ISO MGI:104798 (MGI:3607973|PMID:16260493) RGD PMID:16260493 MGI:3607973 NCBI chr 5:47,183,142...47,244,424
Ensembl chr 5:47,186,558...47,244,416
Ensembl chr 9:47,186,558...47,244,416
JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 involved_in ISO (PMID:10756100) RGD PMID:10756100 NCBI chr 7:130,430,588...130,440,838
Ensembl chr 7:130,431,213...130,440,703
JBrowse link
G Maz MYC associated zinc finger protein involved_in ISO (PMID:25487955) RGD PMID:25487955 NCBI chr 1:198,456,699...198,460,126
Ensembl chr 1:198,456,699...198,460,126
JBrowse link
G Meis3 Meis homeobox 3 acts_upstream_of_or_within ISO (MGI:4848231|PMID:21059917) RGD PMID:21059917 MGI:4848231 NCBI chr 1:78,065,617...78,079,698
Ensembl chr 1:78,068,931...78,079,862
JBrowse link
G Mnt MAX network transcriptional repressor acts_upstream_of_or_within ISO MGI:2678322 (MGI:2675510|PMID:12970171) RGD PMID:12970171 MGI:2675510 NCBI chr10:61,683,776...61,700,504
Ensembl chr10:61,685,241...61,700,491
JBrowse link
G Mrtfa myocardin related transcription factor A acts_upstream_of_or_within ISO (MGI:2183867|PMID:12019265) RGD PMID:12019265 MGI:2183867 NCBI chr 7:122,233,196...122,403,661
Ensembl chr 7:122,234,012...122,403,667
JBrowse link
G Nanos3 nanos C2HC-type zinc finger 3 acts_upstream_of_or_within ISO MGI:2682607|MGI:99702 (MGI:3796786|PMID:18436203) RGD PMID:18436203 MGI:3796786 NCBI chr19:25,284,907...25,288,680
Ensembl chr19:25,284,909...25,288,335
JBrowse link
G Nog noggin involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1862000 (MGI:3640733|PMID:16712836)
Ensembl
RGD
PMID:16712836 GO_REF:0000107 MGI:3640733 NCBI chr10:76,811,759...76,813,386
Ensembl chr10:76,811,759...76,813,386
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 involved_in ISO
IEA
(PMID:19429166)
GO_REF:0000107
RGD
Ensembl
PMID:19429166 GO_REF:0000107 NCBI chr 3:43,111,258...43,128,391
Ensembl chr 3:43,111,240...43,119,159
JBrowse link
G Pam16 presequence translocase associated motor 16 acts_upstream_of_or_within ISO (MGI:4837988|PMID:20719856) RGD PMID:20719856 MGI:4837988 NCBI chr10:11,146,359...11,153,936
Ensembl chr10:11,146,359...11,153,936
JBrowse link
G Pcgf2 polycomb group ring finger 2 acts_upstream_of_or_within ISO MGI:88174 (MGI:1932296|PMID:11290297) RGD PMID:11290297 MGI:1932296 NCBI chr10:85,631,829...85,642,591
Ensembl chr10:85,632,819...85,636,902
JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within ISO MGI:109284 (MGI:3044464|PMID:15148382) RGD PMID:15148382 MGI:3044464 NCBI chr 6:107,169,514...107,221,000
Ensembl chr 6:107,169,528...107,216,798
JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO MGI:1202717 (MGI:3044464|PMID:15148382) RGD PMID:15148382 MGI:3044464 NCBI chr13:98,513,600...98,539,347
Ensembl chr13:98,513,570...98,530,724
JBrowse link
G Qars1 glutaminyl-tRNA synthetase 1 involved_in ISO (PMID:11096076) RGD PMID:11096076 NCBI chr 8:117,297,670...117,305,708
Ensembl chr 8:117,297,670...117,305,702
JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in IMP PMID:24027266 ARUK-UCL PMID:24027266 RGD:14397580 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO (PMID:21075086) RGD PMID:21075086 NCBI chr 7:141,039,433...141,070,269
Ensembl chr 7:141,034,982...141,069,989
JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO RNAcentral:URS0000330617_9606 (PMID:31124343) RGD PMID:31124343 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Wnt4 Wnt family member 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:88276|MGI:96571 (MGI:4454604|PMID:20454446)
Ensembl
RGD
PMID:20454446 GO_REF:0000107 MGI:4454604 NCBI chr 5:155,649,238...155,668,065
Ensembl chr 5:155,649,217...155,672,579
JBrowse link
negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Caap1 caspase activity and apoptosis inhibitor 1 involved_in ISO
IBA
(PMID:21980415)
PMID:21873635
RGD PMID:21980415, PMID:21873635 RGD:13792537 NCBI chr 5:113,479,416...113,532,961
Ensembl chr 5:113,480,547...113,532,878
JBrowse link
G Mmp9 matrix metallopeptidase 9 involved_in IEA
ISO
GO_REF:0000107
(PMID:22984561)
Ensembl
RGD
PMID:22984561 GO_REF:0000107 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Nle1 notchless homolog 1 acts_upstream_of_or_within ISO MGI:2671871|MGI:2671874 (MGI:5468737|PMID:23231322) RGD PMID:23231322 MGI:5468737 NCBI chr10:70,250,959...70,261,880
Ensembl chr10:70,250,959...70,259,553
JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:21785459)
ParkinsonsUK-UCL
Ensembl
RGD
PMID:21785459 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Pih1d1 PIH1 domain containing 1 involved_in ISO (PMID:21078300) RGD PMID:21078300 NCBI chr 1:101,151,240...101,156,806
Ensembl chr 1:101,152,734...101,156,805
JBrowse link
G Plaur plasminogen activator, urokinase receptor involved_in IEA
ISO
GO_REF:0000107
(PMID:22984561)
Ensembl
RGD
PMID:22984561 GO_REF:0000107 NCBI chr 1:81,328,171...81,344,954
Ensembl chr 1:81,328,183...81,344,708
JBrowse link
negative regulation of death-inducing signaling complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nol3 nucleolar protein 3 involved_in IDA PMID:12191471
PMID:15383280
UniProt PMID:12191471, PMID:15383280 RGD:631884, RGD:10047289 NCBI chr19:37,232,567...37,236,668
Ensembl chr19:37,235,001...37,236,649
JBrowse link
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2l1 Bcl2-like 1 involved_in ISO
ISS
(PMID:29507230)
GO_REF:0000024
RGD
UniProt
PMID:29507230 GO_REF:0000024 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Creb3 cAMP responsive element binding protein 3 involved_in ISO (PMID:16940180) RGD PMID:16940180 NCBI chr 5:59,063,532...59,068,196
Ensembl chr 5:59,063,531...59,068,188
JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 involved_in IMP
ISO
PMID:15665855
(MGI:5616321|PMID:15665855)
RGD PMID:15665855, PMID:15665855 MGI:5616321, RGD:1558627 NCBI chr 3:80,892,433...80,933,283
Ensembl chr 3:80,892,435...80,933,283
JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 acts_upstream_of_or_within ISO MGI:1341830|MGI:99682 (MGI:5525071|PMID:22240901) RGD PMID:22240901 MGI:5525071 NCBI chr 7:117,304,742...117,307,916
Ensembl chr 7:117,304,742...117,307,916
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in ISO
IMP
IBA
(PMID:15102845)
PMID:21873635
RGD PMID:15102845, PMID:15102845, PMID:21873635 RGD:1304324, RGD:13792537 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:12150907), (PMID:20625543) RGD PMID:12150907 PMID:20625543 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:12150907), (PMID:20625543) RGD PMID:12150907 PMID:20625543 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in ISO (MGI:5495588|PMID:23453807) RGD PMID:23453807 MGI:5495588 NCBI chr  X:156,254,187...156,280,046
Ensembl chr  X:156,257,173...156,270,748
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:21857923) RGD PMID:21857923 NCBI chr 7:132,857,311...133,018,549
Ensembl chr 7:132,857,628...133,018,584
JBrowse link
G Ngf nerve growth factor involved_in NAS PMID:21266243 ParkinsonsUK-UCL PMID:21266243 RGD:10047230 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISS
ISO
GO_REF:0000024
(MGI:5495588|PMID:23453807)
UniProtKB:P58281 (PMID:23453807)
ParkinsonsUK-UCL
RGD
PMID:23453807 GO_REF:0000024 MGI:5495588 NCBI chr11:74,717,600...74,793,902
Ensembl chr11:74,720,254...74,793,803
JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO
IEA
UniProtKB:Q99LX0 (PMID:14652021)
(MGI:5613479|PMID:14652021)
GO_REF:0000107
RGD
Ensembl
PMID:14652021 GO_REF:0000107 MGI:5613479 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 acts_upstream_of_or_within ISO MGI:2181360 (MGI:4836774|PMID:20811152) RGD PMID:20811152 MGI:4836774 NCBI chr12:9,496,044...9,501,211
Ensembl chr12:9,496,044...9,501,213
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISS
ISO
GO_REF:0000024
(MGI:5433837|PMID:21113145)
(PMID:10973942), (PMID:11439185), (PMID:12150907), (PMID:21113145), (PMID:23453807)
ParkinsonsUK-UCL
RGD
PMID:10973942 PMID:11439185 PMID:12150907 PMID:21113145 PMID:23453807 GO_REF:0000024 MGI:5433837 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO (MGI:5619464|PMID:21216966) RGD PMID:21216966 MGI:5619464 NCBI chr 3:164,665,462...164,711,936
Ensembl chr 3:164,665,532...164,711,848
JBrowse link
G Selenos selenoprotein S involved_in ISO
IEA
(PMID:17210132)
GO_REF:0000107
RGD
Ensembl
PMID:17210132 GO_REF:0000107 NCBI chr 1:126,979,579...126,989,344
Ensembl chr 1:126,979,575...126,989,344
JBrowse link
G Syvn1 synoviolin 1 involved_in
acts_upstream_of_or_within
ISO (PMID:12459480), (PMID:17059562)
MGI:2679656 (MGI:3575050|PMID:15611074)
RGD PMID:12459480 PMID:15611074 PMID:17059562 MGI:3575050 NCBI chr 1:221,409,281...221,416,229
Ensembl chr 1:221,409,271...221,417,886
JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in
acts_upstream_of_or_within
ISO (PMID:21075086)
MGI:1913418 (MGI:5525071|PMID:22240901)
RGD PMID:21075086 PMID:22240901 MGI:5525071 NCBI chr 7:141,039,433...141,070,269
Ensembl chr 7:141,034,982...141,069,989
JBrowse link
G Txndc12 thioredoxin domain containing 12 acts_upstream_of_or_within ISO (PMID:18628206) RGD PMID:18628206 NCBI chr 5:128,450,830...128,475,858
Ensembl chr 5:128,450,680...128,475,864
JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in ISO (MGI:3629256|PMID:16571599) RGD PMID:16571599 MGI:3629256 NCBI chr14:78,640,707...78,665,224
Ensembl chr14:78,640,620...78,665,966
JBrowse link
G Xbp1 X-box binding protein 1 involved_in IEA
IMP
ISO
GO_REF:0000107
PMID:20625543
(PMID:19135031)
Ensembl
RGD
PMID:19135031, PMID:20625543 GO_REF:0000107, RGD:10047191 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hyou1 hypoxia up-regulated 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:3697528|PMID:17116640)
Ensembl
RGD
PMID:17116640 GO_REF:0000107 MGI:3697528 NCBI chr 8:48,699,796...48,711,912
Ensembl chr 8:48,699,769...48,711,910
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO UniProtKB:O15354 (MGI:3697528|PMID:17116640), (MGI:5495588|PMID:23453807) RGD PMID:17116640 PMID:23453807 MGI:3697528 MGI:5495588 NCBI chr 1:48,880,015...50,069,998 JBrowse link
negative regulation of extrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO
IEA
(PMID:9884026)
GO_REF:0000107
RGD
Ensembl
PMID:9884026 GO_REF:0000107 NCBI chr 3:44,432,476...44,539,680
Ensembl chr 3:44,432,471...44,522,930
JBrowse link
G Ar androgen receptor involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:21310825)
Ensembl
BHF-UCL
RGD
PMID:21310825 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Birc6 baculoviral IAP repeat-containing 6 involved_in ISO (PMID:14765125) RGD PMID:14765125 NCBI chr 6:21,900,763...22,092,484
Ensembl chr 6:21,950,100...22,092,346
JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO
GO_REF:0000107
(MGI:3039210|PMID:15070745)
Ensembl
RGD
PMID:15070745 GO_REF:0000107 MGI:3039210 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator involved_in
acts_upstream_of_or_within
ISO (PMID:22266862), (PMID:9208847)
MGI:109324|MGI:2154952 (MGI:5486419|PMID:22675671)
RGD PMID:9208847 PMID:22266862 PMID:22675671 MGI:5486419 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Cttn cortactin acts_upstream_of_or_within ISO MGI:1924375 (MGI:5437589|PMID:22660580) RGD PMID:22660580 MGI:5437589 NCBI chr 1:217,602,698...217,638,196
NCBI chr 1:215,255,385...215,290,882
Ensembl chr 1:217,602,698...217,638,152
Ensembl chr 1:217,602,698...217,638,152
JBrowse link
G Dab2 DAB adaptor protein 2 acts_upstream_of_or_within ISO (MGI:5442513|PMID:15734730) RGD PMID:15734730 MGI:5442513 NCBI chr 2:55,747,353...55,768,848
Ensembl chr 2:55,747,318...55,768,270
JBrowse link
G Fcmr Fc fragment of IgM receptor acts_upstream_of_or_within ISO (MGI:3576402|PMID:15632112) RGD PMID:15632112 MGI:3576402 NCBI chr13:47,602,701...47,617,065
Ensembl chr13:47,602,692...47,617,064
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within ISO MGI:104995 (MGI:3047441|PMID:15288121) RGD PMID:15288121 MGI:3047441 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit acts_upstream_of_or_within ISO MGI:104990 (MGI:3047441|PMID:15288121) RGD PMID:15288121 MGI:3047441 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISO (PMID:16636664) RGD PMID:16636664 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Htt huntingtin involved_in ISO
IEA
(PMID:19240112)
GO_REF:0000107
RGD
Ensembl
PMID:19240112 GO_REF:0000107 NCBI chr14:81,105,139...81,254,637
Ensembl chr14:81,105,139...81,254,637
JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA
IDA
(PMID:16942485)
GO_REF:0000107
PMID:17023532
RGD
Ensembl
PMID:16942485, PMID:17023532 GO_REF:0000107, RGD:1600072 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Il19 interleukin 19 acts_upstream_of_or_within ISO (MGI:5491082|PMID:23468852) RGD PMID:23468852 MGI:5491082 NCBI chr13:47,663,592...47,677,869
Ensembl chr13:47,664,080...47,670,407
JBrowse link
G Il4 interleukin 4 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:1340173|PMID:10429671)
RGD PMID:10429671, PMID:21873635 MGI:1340173, RGD:13792537 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il7 interleukin 7 acts_upstream_of_or_within ISO (MGI:1340173|PMID:10429671) RGD PMID:10429671 MGI:1340173 NCBI chr 2:96,427,884...96,474,979
Ensembl chr 2:96,439,286...96,474,977
JBrowse link
G Itga6 integrin subunit alpha 6 involved_in ISO (PMID:21310825) RGD PMID:21310825 NCBI chr 3:58,442,904...58,515,124
Ensembl chr 3:58,443,101...58,515,124
JBrowse link
G Itgav integrin subunit alpha V involved_in ISO (PMID:10708943) RGD PMID:10708943 NCBI chr 3:71,113,269...71,205,958
Ensembl chr 3:71,114,100...71,202,411
JBrowse link
G Lgals3 galectin 3 involved_in IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(PMID:22761016)
Ensembl
RGD
PMID:22761016, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Lmna lamin A/C involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:4879057|PMID:21151901)
Ensembl
RGD
PMID:21151901 GO_REF:0000107 MGI:4879057 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
JBrowse link
G Nol3 nucleolar protein 3 involved_in ISO
IEA
(PMID:9560245)
GO_REF:0000107
RGD
Ensembl
PMID:9560245 GO_REF:0000107 NCBI chr19:37,232,567...37,236,668
Ensembl chr19:37,235,001...37,236,649
JBrowse link
G Nrp1 neuropilin 1 involved_in ISO (MGI:5287519|PMID:21828096) RGD PMID:21828096 MGI:5287519 NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858
JBrowse link
G Pak5 p21 (RAC1) activated kinase 5 acts_upstream_of_or_within ISO (MGI:2673247|PMID:12897128) RGD PMID:12897128 MGI:2673247 NCBI chr 3:129,042,232...129,357,512
Ensembl chr 3:129,042,742...129,357,491
JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO
ISS
(PMID:21785459)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:21785459 GO_REF:0000024 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Peli3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO MGI:5441750 (MGI:5546581|PMID:23950925)
(PMID:24113711)
RGD PMID:23950925 PMID:24113711 MGI:5546581 NCBI chr 1:220,191,209...220,204,032
Ensembl chr 1:220,190,067...220,204,032
JBrowse link
G Phip pleckstrin homology domain interacting protein acts_upstream_of_or_within ISO (PMID:17636024) RGD PMID:17636024 NCBI chr 8:90,387,339...90,483,964
Ensembl chr 8:90,392,143...90,483,077
JBrowse link
G Prdx2 peroxiredoxin 2 acts_upstream_of_or_within ISO MGI:2668456 (MGI:3050700|PMID:15259009) RGD PMID:15259009 MGI:3050700 NCBI chr19:26,084,816...26,090,095
Ensembl chr19:26,084,903...26,090,094
JBrowse link
G Psme3 proteasome activator subunit 3 involved_in ISO (PMID:18309296) RGD PMID:18309296 NCBI chr10:89,236,256...89,244,041
Ensembl chr10:89,236,256...89,244,041
JBrowse link
G Rb1cc1 RB1-inducible coiled-coil 1 acts_upstream_of_or_within ISO MGI:3690329 (MGI:3689241|PMID:17015619) RGD PMID:17015619 MGI:3689241 NCBI chr 5:13,033,918...13,097,369
Ensembl chr 5:13,033,918...13,097,341
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in
acts_upstream_of_or_within
ISO (PMID:21310825)
(MGI:5304595|PMID:22244329)
RGD PMID:21310825 PMID:22244329 MGI:5304595 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in
acts_upstream_of_or_within
ISO (PMID:21525013)
MGI:104798|MGI:109200 (MGI:5521568|PMID:22089168)
RGD PMID:21525013 PMID:22089168 MGI:5521568 NCBI chr17:31,537,580...31,569,904
Ensembl chr17:31,537,591...31,569,904
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 acts_upstream_of_or_within ISO (MGI:4456959|PMID:11493700) RGD PMID:11493700 MGI:4456959 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G Scg2 secretogranin II involved_in IEA
ISO
GO_REF:0000107
(PMID:14970115)
Ensembl
RGD
PMID:14970115 GO_REF:0000107 NCBI chr 9:85,237,460...85,243,024
Ensembl chr 9:85,237,458...85,243,001
JBrowse link
G Sgms1 sphingomyelin synthase 1 acts_upstream_of_or_within ISO (MGI:3609513|PMID:16226406) RGD PMID:16226406 MGI:3609513 NCBI chr 1:250,692,448...250,951,685
Ensembl chr 1:250,691,370...250,951,697
JBrowse link
G Sh3rf1 SH3 domain containing ring finger 1 involved_in ISO (PMID:21586138) RGD PMID:21586138 NCBI chr16:32,062,425...32,227,526
Ensembl chr16:32,062,336...32,227,491
JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 involved_in ISO (PMID:21586138) RGD PMID:21586138 NCBI chr 2:148,874,151...148,891,900
Ensembl chr 2:148,874,151...148,891,900
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO
IBA
(PMID:19767770)
PMID:21873635
RGD PMID:19767770, PMID:21873635 RGD:13792537 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Tcf7l2 transcription factor 7 like 2 involved_in IMP PMID:21965303 BHF-UCL PMID:21965303 RGD:14974246 NCBI chr 1:276,686,911...276,730,517
Ensembl chr 1:276,659,542...276,730,514
Ensembl chr 1:276,659,542...276,730,514
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO (PMID:18625725) RGD PMID:18625725 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 involved_in ISO (MGI:2150820|PMID:11567634) RGD PMID:11567634 MGI:2150820 NCBI chr 5:173,447,784...173,450,474
Ensembl chr 5:173,447,784...173,450,474
JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (MGI:5287519|PMID:21828096) RGD PMID:21828096 MGI:5287519 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Yap1 Yes1 associated transcriptional regulator acts_upstream_of_or_within ISO MGI:95484 (MGI:3818355|PMID:17980593) RGD PMID:17980593 MGI:3818355 NCBI chr 8:6,133,014...6,204,240
Ensembl chr 8:6,135,493...6,203,579
JBrowse link
G Zmynd11 zinc finger, MYND-type containing 11 involved_in ISO (PMID:20732415) RGD PMID:20732415 NCBI chr17:63,825,616...63,914,740
Ensembl chr17:63,825,627...63,879,171
JBrowse link
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 involved_in IMP PMID:18469807 UniProt PMID:18469807 RGD:8553892 NCBI chr 7:70,360,199...70,377,422
Ensembl chr 7:70,364,813...70,377,422
JBrowse link
G Bcl2 BCL2, apoptosis regulator acts_upstream_of_or_within ISO MGI:99702 (PMID:8358790) RGD PMID:8358790 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l10 BCL2 like 10 acts_upstream_of_or_within ISO (MGI:1326939|PMID:9878060) RGD PMID:9878060 MGI:1326939 NCBI chr 8:82,288,705...82,294,750
Ensembl chr 8:82,288,705...82,294,744
JBrowse link
G Col2a1 collagen type II alpha 1 chain involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2152978 (MGI:1097047|PMID:9299161)
Ensembl
RGD
PMID:9299161 GO_REF:0000107 MGI:1097047 NCBI chr 7:139,454,945...139,484,403
Ensembl chr 7:139,455,242...139,483,997
JBrowse link
G Csf2 colony stimulating factor 2 involved_in ISO (PMID:10666185) RGD PMID:10666185 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Ctnna1 catenin alpha 1 acts_upstream_of_or_within ISO MGI:2677796 (MGI:5315030|PMID:22411810) RGD PMID:22411810 MGI:5315030 NCBI chr18:27,923,229...28,055,972
Ensembl chr18:27,923,572...28,055,960
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3777228|PMID:18322241), (MGI:3833195|PMID:18971423)
Ensembl
RGD
PMID:18322241 PMID:18971423 GO_REF:0000107 MGI:3777228 MGI:3833195 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 acts_upstream_of_or_within ISO MGI:2670351 (MGI:3833195|PMID:18971423) RGD PMID:18971423 MGI:3833195 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514
JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1857803 (MGI:3577160|PMID:15817220)
RGD PMID:15817220, PMID:21873635 MGI:3577160, RGD:13792537 NCBI chr 5:4,275,728...4,495,525
Ensembl chr 5:4,373,626...4,513,142
JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:162,285,275...162,470,642
Ensembl chr 3:162,346,490...162,470,065
JBrowse link
G Eya3 EYA transcriptional coactivator and phosphatase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:150,833,754...150,915,390
Ensembl chr 5:150,787,043...150,913,757
JBrowse link
G Eya4 EYA transcriptional coactivator and phosphatase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:23,237,617...23,611,580
Ensembl chr 1:23,409,408...23,610,164
JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647 (MGI:3690587|PMID:16956603) RGD PMID:16956603 MGI:3690587 NCBI chr 2:51,673,480...51,747,533
Ensembl chr 2:51,672,722...51,750,369
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in IMP PMID:18469807 UniProt PMID:18469807 RGD:8553892 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317
JBrowse link
G Gas1 growth arrest-specific 1 acts_upstream_of_or_within ISO (MGI:5306314|PMID:15070677) RGD PMID:15070677 MGI:5306314 NCBI chr17:4,846,116...4,849,350
Ensembl chr17:4,846,789...4,847,940
JBrowse link
G Gata1 GATA binding protein 1 involved_in ISO (PMID:17167422) RGD PMID:17167422 NCBI chr  X:15,273,937...15,281,759
Ensembl chr  X:15,378,789...15,382,066
Ensembl chr  X:15,378,789...15,382,066
JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in ISO
IEA
(PMID:10921886)
GO_REF:0000107
RGD
Ensembl
PMID:10921886 GO_REF:0000107 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Gfral GDNF family receptor alpha like acts_upstream_of_or_within ISO (MGI:3610244|PMID:16086688) RGD PMID:16086688 MGI:3610244 NCBI chr 8:83,235,647...83,282,635
Ensembl chr 8:83,236,103...83,280,888
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:17167422) RGD PMID:17167422 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:17167422) RGD PMID:17167422 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Il1b interleukin 1 beta involved_in ISO
IEA
(PMID:10748004)
GO_REF:0000107
RGD
Ensembl
PMID:10748004 GO_REF:0000107 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il7 interleukin 7 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:84869|PMID:8950980)
Ensembl
RGD
PMID:8950980 GO_REF:0000107 MGI:84869 NCBI chr 2:96,427,884...96,474,979
Ensembl chr 2:96,439,286...96,474,977
JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 involved_in IMP PMID:20551324 BHF-UCL PMID:20551324 RGD:8553940 NCBI chr 8:68,055,976...68,282,656
Ensembl chr 8:68,055,972...68,282,590
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 involved_in ISO UniProtKB:Q62862 (PMID:20551324) RGD PMID:20551324 NCBI chr10:47,768,592...47,775,130
Ensembl chr10:47,766,680...47,775,055
Ensembl chr10:47,766,680...47,775,055
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in ISO (PMID:20921992) RGD PMID:20921992 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Nrg1 neuregulin 1 involved_in ISO (PMID:9553078) RGD PMID:9553078 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Pf4 platelet factor 4 involved_in ISO (PMID:10666185) RGD PMID:10666185 NCBI chr14:18,848,549...18,849,258
Ensembl chr14:18,848,549...18,849,258
JBrowse link
G Prdx2 peroxiredoxin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:86755|PMID:9115640)
Ensembl
RGD
PMID:9115640 GO_REF:0000107 MGI:86755 NCBI chr19:26,084,816...26,090,095
Ensembl chr19:26,084,903...26,090,094
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in ISO (MGI:5306563|PMID:20125124) RGD PMID:20125124 MGI:5306563 NCBI chr17:31,537,580...31,569,904
Ensembl chr17:31,537,591...31,569,904
JBrowse link
G Sgk3 serum/glucocorticoid regulated kinase family, member 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:2178763|PMID:11050396)
Ensembl
RGD
PMID:11050396 GO_REF:0000107 MGI:2178763 NCBI chr 5:9,046,889...9,094,740
Ensembl chr 5:9,048,614...9,094,616
JBrowse link
G Snai2 snail family transcriptional repressor 2 acts_upstream_of_or_within ISO (MGI:5142392|PMID:10518215) RGD PMID:10518215 MGI:5142392 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link
G Stradb STE20 related adaptor beta acts_upstream_of_or_within ISO (MGI:2656105|PMID:12574163) RGD PMID:12574163 MGI:2656105 NCBI chr 9:65,763,437...65,782,513
Ensembl chr 9:65,763,437...65,782,513
JBrowse link
G Tert telomerase reverse transcriptase involved_in ISO (PMID:10449030) RGD PMID:10449030 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:10666185), (PMID:10748004) RGD PMID:10666185 PMID:10748004 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Unc5b unc-5 netrin receptor B involved_in ISO
IEA
(PMID:18469807)
GO_REF:0000107
RGD
Ensembl
PMID:18469807 GO_REF:0000107 NCBI chr20:30,339,680...30,406,593
Ensembl chr20:30,339,673...30,406,295
JBrowse link
G Zc3hc1 zinc finger, C3HC-type containing 1 acts_upstream_of_or_within ISO (MGI:2670822|PMID:12748172) RGD PMID:12748172 MGI:2670822 NCBI chr 4:57,684,678...57,706,613
Ensembl chr 4:57,684,678...57,706,613
JBrowse link
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:22711822) RGD PMID:22711822 NCBI chr 2:187,964,100...188,022,847
Ensembl chr 2:187,977,008...188,021,377
JBrowse link
G Bcl2l1 Bcl2-like 1 acts_upstream_of_or_within ISO (PMID:26582200) RGD PMID:26582200 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Brca1 BRCA1, DNA repair associated involved_in ISO
IEA
(PMID:23415688)
GO_REF:0000107
RGD
Ensembl
PMID:23415688 GO_REF:0000107 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Caps calcyphosine acts_upstream_of_or_within ISO (MGI:2450205|PMID:12466268) RGD PMID:12466268 MGI:2450205
G Cflar CASP8 and FADD-like apoptosis regulator involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:26582200)
(PMID:18202225)
RGD PMID:18202225 PMID:26582200, PMID:21873635 RGD:13792537 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Dapk1 death associated protein kinase 1 acts_upstream_of_or_within ISO (MGI:2152512|PMID:11485996) RGD PMID:11485996 MGI:2152512 NCBI chr17:4,297,038...4,454,941
Ensembl chr17:4,297,224...4,454,778
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:18846110) RGD PMID:18846110 NCBI chr  X:10,400,363...10,414,010
Ensembl chr  X:10,400,366...10,413,995
JBrowse link
G Faim Fas apoptotic inhibitory molecule involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:1332875|PMID:10075978)
RGD PMID:10075978, PMID:21873635 MGI:1332875, RGD:13792537 NCBI chr 8:107,225,119...107,247,228
Ensembl chr 8:107,225,212...107,241,224
Ensembl chr 8:107,225,212...107,241,224
JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 acts_upstream_of_or_within ISO (PMID:26582200) RGD PMID:26582200 NCBI chr 7:141,158,769...141,185,781
Ensembl chr 7:141,157,963...141,185,710
JBrowse link
G Fga fibrinogen alpha chain involved_in IBA
ISO
PMID:21873635
(PMID:10903502)
RGD PMID:10903502, PMID:21873635 RGD:13792537 NCBI chr 2:181,997,562...182,013,726
Ensembl chr 2:182,006,242...182,013,763
JBrowse link
G Fgb fibrinogen beta chain involved_in ISO (PMID:10903502) RGD PMID:10903502 NCBI chr 2:182,028,044...182,035,026
Ensembl chr 2:182,027,115...182,038,178
JBrowse link
G Fgg fibrinogen gamma chain involved_in ISO (PMID:10903502) RGD PMID:10903502 NCBI chr 2:181,987,080...181,994,523
Ensembl chr 2:181,987,217...181,994,514
JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:12221075)
Ensembl
RGD
PMID:12221075 GO_REF:0000107 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:18846110)
UniProt
Ensembl
RGD
PMID:18846110 GO_REF:0000024 GO_REF:0000107 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Hgf hepatocyte growth factor acts_upstream_of_or_within ISO (MGI:3054501|PMID:15314156) RGD PMID:15314156 MGI:3054501 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hmgb2 high mobility group box 2 acts_upstream_of_or_within ISO MGI:2387671 (MGI:3831045|PMID:19139395) RGD PMID:19139395 MGI:3831045 NCBI chr16:36,077,615...36,080,191
Ensembl chr16:36,077,617...36,080,191
Ensembl chr11:36,077,617...36,080,191
JBrowse link
G Hmox1 heme oxygenase 1 involved_in ISO (PMID:18202225) RGD PMID:18202225 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Icam1 intercellular adhesion molecule 1 involved_in ISO (PMID:10903502) RGD PMID:10903502 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Itprip inositol 1,4,5-trisphosphate receptor interacting protein acts_upstream_of_or_within ISO MGI:1916885 (MGI:4431305|PMID:20053891) RGD PMID:20053891 MGI:4431305 NCBI chr 1:267,649,385...267,673,341
NCBI chr 1:271,252,447...271,272,169
Ensembl chr 1:267,651,320...267,653,389
Ensembl chr 1:267,651,320...267,653,389
JBrowse link
G LOC684466 similar to Fas apoptotic inhibitory molecule 1 (rFAIM) involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:107,480,451...107,495,215
Ensembl chr 8:107,480,650...107,490,093
JBrowse link
G Nol3 nucleolar protein 3 involved_in IMP PMID:12191471
PMID:15383280
UniProt PMID:12191471, PMID:15383280 RGD:631884, RGD:10047289 NCBI chr19:37,232,567...37,236,668
Ensembl chr19:37,235,001...37,236,649
JBrowse link
G Pea15 proliferation and apoptosis adaptor protein 15 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:10442631)
(MGI:3687663|PMID:10588860)
PMID:21873635
RGD PMID:10442631 PMID:10588860, PMID:21873635 MGI:3687663, RGD:13792537 NCBI chr13:90,579,844...90,589,466
Ensembl chr13:90,579,846...90,589,466
JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO (MGI:1099227|PMID:9353287) RGD PMID:9353287 MGI:1099227 NCBI chr13:98,513,600...98,539,347
Ensembl chr13:98,513,570...98,530,724
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO MGI:2388026|MGI:95484|MGI:99255 (MGI:3612236|PMID:16365167) RGD PMID:16365167 MGI:3612236 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase involved_in IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:15069192)
UniProt
RGD
PMID:15069192, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr10:70,157,621...70,220,618
Ensembl chr10:70,157,621...70,220,582
JBrowse link
G Rnf34 ring finger protein 34 involved_in IBA
ISO
ISS
PMID:21873635
(PMID:15069192)
GO_REF:0000024
RGD
UniProt
PMID:15069192, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr12:39,164,290...39,185,209
Ensembl chr12:39,164,290...39,185,168
JBrowse link
G Serpine1 serpin family E member 1 involved_in ISO
IEA
(PMID:18835034)
GO_REF:0000107
RGD
Ensembl
PMID:18835034 GO_REF:0000107 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 involved_in ISO (MGI:4835156|PMID:9391078) RGD PMID:9391078 MGI:4835156 NCBI chr 2:182,723,732...182,731,277
Ensembl chr 2:182,723,854...182,731,764
JBrowse link
G Tmbim1 transmembrane BAX inhibitor motif containing 1 involved_in ISO
ISS
(PMID:21107705)
GO_REF:0000024
RGD
UniProt
PMID:21107705 GO_REF:0000024 NCBI chr 9:81,569,289...81,586,469
Ensembl chr 9:81,569,289...81,586,553
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (PMID:12167698) RGD PMID:12167698 NCBI chr 1:14,401,103...14,416,369
Ensembl chr 1:14,402,913...14,412,807
JBrowse link
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in IEA
ISO
GO_REF:0000107
(MGI:5613479|PMID:14652021)
UniProtKB:Q99LX0 (PMID:14652021)
Ensembl
RGD
PMID:14652021 GO_REF:0000107 MGI:5613479 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:21177249), (PMID:23261939) RGD PMID:21177249 PMID:23261939 NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415
JBrowse link
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eno1 enolase 1 involved_in ISO UniProtKB:Q01986 (PMID:15459207) RGD PMID:15459207 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G Hyou1 hypoxia up-regulated 1 involved_in IBA
IEA
ISO
IDA
PMID:21873635
GO_REF:0000107
(PMID:10037731)
PMID:11231630
Ensembl
RGD
PMID:10037731, PMID:21873635, PMID:11231630 GO_REF:0000107, RGD:13792537, RGD:10047348 NCBI chr 8:48,699,796...48,711,912
Ensembl chr 8:48,699,769...48,711,910
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 involved_in IGI
IMP
PMID:15459207 CAFA PMID:15459207, PMID:15459207 RGD:12793039, RGD:12793039 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Nol3 nucleolar protein 3 involved_in IDA PMID:10590251 UniProt PMID:10590251 RGD:10047155 NCBI chr19:37,232,567...37,236,668
Ensembl chr19:37,235,001...37,236,649
JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta involved_in IEA
ISO
GO_REF:0000107
(MGI:6444553|PMID:30496354)
Ensembl
RGD
PMID:30496354 GO_REF:0000107 MGI:6444553 NCBI chr 8:107,275,849...107,381,088
Ensembl chr 8:107,275,725...107,380,933
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (MGI:5558956|PMID:24553947) RGD PMID:24553947 MGI:5558956 NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415
JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO (PMID:21075086) RGD PMID:21075086 NCBI chr 7:141,039,433...141,070,269
Ensembl chr 7:141,034,982...141,069,989
JBrowse link
negative regulation of intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC098008.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 1:167,765,040...167,765,552 JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (MGI:4999711|PMID:19911006) RGD PMID:19911006 MGI:4999711 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in ISO
IEA
IBA
(PMID:11684014)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:11684014, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in IBA
ISO
PMID:21873635
(PMID:21567405)
(PMID:12011449)
RGD PMID:12011449 PMID:21567405, PMID:21873635 RGD:13792537 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl2l10 BCL2 like 10 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:1326939|PMID:9878060)
RGD PMID:9878060, PMID:21873635 MGI:1326939, RGD:13792537 NCBI chr 8:82,288,705...82,294,750
Ensembl chr 8:82,288,705...82,294,744
JBrowse link
G Bcl2l2 Bcl2-like 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:33,543,774...33,549,165
Ensembl chr15:33,544,312...33,549,164
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:21883093) RGD PMID:21883093 NCBI chr  X:10,400,363...10,414,010
Ensembl chr  X:10,400,366...10,413,995
JBrowse link
G Fignl1 fidgetin-like 1 acts_upstream_of_or_within ISO (MGI:4944122|PMID:20886204) RGD PMID:20886204 MGI:4944122 NCBI chr14:91,895,902...91,904,474
Ensembl chr14:91,895,909...91,904,433
JBrowse link
G G2e3 G2/M-phase specific E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:3808723 (MGI:3807157|PMID:18511420) RGD PMID:18511420 MGI:3807157 NCBI chr 6:72,092,148...72,123,878
Ensembl chr 6:72,092,194...72,122,497
JBrowse link
G Gcg glucagon involved_in ISO (MGI:4453294|PMID:19915011) RGD PMID:19915011 MGI:4453294 NCBI chr 3:48,442,635...48,451,650
Ensembl chr 3:48,442,635...48,451,650
JBrowse link
G Hdac1 histone deacetylase 1 acts_upstream_of_or_within ISO MGI:1097691 (MGI:4889029|PMID:21093383) RGD PMID:21093383 MGI:4889029 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hdac2 histone deacetylase 2 acts_upstream_of_or_within ISO MGI:108086 (MGI:4889029|PMID:21093383) RGD PMID:21093383 MGI:4889029 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Hells helicase, lymphoid specific acts_upstream_of_or_within ISO MGI:2178586 (MGI:2178571|PMID:11325543) RGD PMID:11325543 MGI:2178571 NCBI chr 1:257,901,856...257,953,889
Ensembl chr 1:257,766,691...257,949,183
Ensembl chr 1:257,766,691...257,949,183
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in IGI
ISO
PMID:22045699
UniProtKB:P37840 (PMID:22045699)
RGD PMID:22045699, PMID:22045699 RGD:10047316 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254
JBrowse link
G Ivns1abp influenza virus NS1A binding protein acts_upstream_of_or_within ISO MGI:4820513 (MGI:4819697|PMID:15485691) RGD PMID:15485691 MGI:4819697 NCBI chr13:68,702,970...68,722,472
Ensembl chr13:68,702,820...68,722,472
JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 acts_upstream_of_or_within ISO (MGI:1332866|PMID:10098834) RGD PMID:10098834 MGI:1332866 NCBI chr 3:81,295,023...81,304,181
Ensembl chr 3:81,295,024...81,304,181
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Mmp9 matrix metallopeptidase 9 involved_in IEA
ISO
GO_REF:0000107
(PMID:22984561)
Ensembl
RGD
PMID:22984561 GO_REF:0000107 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 involved_in ISO (PMID:16826196) RGD PMID:16826196 NCBI chr16:21,275,311...21,282,246
Ensembl chr16:21,275,311...21,282,246
JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 involved_in ISO (PMID:16826196) RGD PMID:16826196 NCBI chr 3:79,721,686...79,728,863
Ensembl chr 3:79,721,694...79,728,879
JBrowse link
G Noc2l NOC2-like nucleolar associated transcriptional repressor involved_in ISO (PMID:16322561) RGD PMID:16322561 NCBI chr 5:173,659,796...173,672,699
Ensembl chr 5:173,660,921...173,672,459
JBrowse link
G Nol3 nucleolar protein 3 involved_in IMP PMID:15383280 UniProt PMID:15383280 RGD:10047289 NCBI chr19:37,232,567...37,236,668
Ensembl chr19:37,235,001...37,236,649
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISO (MGI:3692706|PMID:16839884) RGD PMID:16839884 MGI:3692706 NCBI chr11:74,717,600...74,793,902
Ensembl chr11:74,720,254...74,793,803
JBrowse link
G Parl presenilin associated, rhomboid-like involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:3692706|PMID:16839884)
GO_REF:0000107
ParkinsonsUK-UCL
RGD
Ensembl
PMID:16839884 GO_REF:0000024 GO_REF:0000107 MGI:3692706 NCBI chr11:84,517,368...84,544,463
Ensembl chr11:84,517,368...84,544,462
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:15087508) RGD PMID:15087508 NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415
JBrowse link
G Plaur plasminogen activator, urokinase receptor involved_in ISO
IEA
(PMID:22984561)
GO_REF:0000107
RGD
Ensembl
PMID:22984561 GO_REF:0000107 NCBI chr 1:81,328,171...81,344,954
Ensembl chr 1:81,328,183...81,344,708
JBrowse link
G Ppif peptidylprolyl isomerase F involved_in ISO
ISS
(PMID:19228691)
GO_REF:0000024
RGD
UniProt
PMID:19228691 GO_REF:0000024 NCBI chr16:1,979,191...1,985,912
Ensembl chr16:1,979,191...1,985,908
JBrowse link
G Rtkn2 rhotekin 2 involved_in ISO (PMID:26124677) RGD PMID:26124677 NCBI chr20:21,919,486...22,004,279
Ensembl chr20:21,932,878...22,004,279
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in IBA
ISO
PMID:21873635
(PMID:19767770)
RGD PMID:19767770, PMID:21873635 RGD:13792537 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Uri1 URI1, prefoldin-like chaperone involved_in ISO (PMID:17936702) RGD PMID:17936702 NCBI chr 1:94,346,513...94,404,362
Ensembl chr 1:94,346,514...94,404,211
JBrowse link
G Vdac2 voltage-dependent anion channel 2 involved_in ISO (MGI:5315363|PMID:12881569) RGD PMID:12881569 MGI:5315363 NCBI chr15:2,634,622...2,648,548
Ensembl chr15:2,634,624...2,648,551
JBrowse link
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Armc10 armadillo repeat containing 10 involved_in IBA
ISO
PMID:21873635
(PMID:17904127)
RGD PMID:17904127, PMID:21873635 RGD:13792537 NCBI chr 4:10,004,846...10,020,017
Ensembl chr 4:10,004,848...10,020,022
JBrowse link
G Cep63 centrosomal protein 63 acts_upstream_of_or_within ISO MGI:98834 (MGI:5662131|PMID:26158450) RGD PMID:26158450 MGI:5662131 NCBI chr 8:111,063,988...111,116,014
Ensembl chr 8:111,064,049...111,116,014
JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in ISO (PMID:17310983) RGD PMID:17310983 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mdm4 MDM4 regulator of p53 involved_in ISO (MGI:2182884|PMID:12101245) RGD PMID:12101245 MGI:2182884 NCBI chr13:49,786,776...49,828,780
Ensembl chr13:49,792,794...49,828,720
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:23985028) RGD PMID:23985028 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Pttg1ip PTTG1 interacting protein acts_upstream_of_or_within ISO (PMID:24506068) RGD PMID:24506068 NCBI chr20:11,746,369...11,764,097
Ensembl chr20:11,746,370...11,764,233
JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B acts_upstream_of_or_within ISO MGI:2672883 (MGI:2670318|PMID:12858174) RGD PMID:12858174 MGI:2670318 NCBI chr 7:76,750,045...76,780,817
Ensembl chr 7:76,750,050...76,780,817
JBrowse link
G Rrn3 RRN3 homolog, RNA polymerase I transcription factor acts_upstream_of_or_within ISO MGI:3584037 (MGI:3583493|PMID:15989966) RGD PMID:15989966 MGI:3583493 NCBI chr10:3,170,387...3,214,648
Ensembl chr10:3,170,742...3,214,655
JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 involved_in ISO (MGI:5553386|PMID:24523556) RGD PMID:24523556 MGI:5553386 NCBI chr 2:250,709,812...250,744,216
Ensembl chr 2:250,709,439...250,744,196
JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ackr3 atypical chemokine receptor 3 involved_in ISO (PMID:20388803) RGD PMID:20388803 NCBI chr 9:97,355,881...97,367,455
Ensembl chr 9:97,355,924...97,367,445
JBrowse link
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of_or_within ISO (MGI:3584078|PMID:15983387) RGD PMID:15983387 MGI:3584078 NCBI chr10:67,427,042...67,475,825
Ensembl chr10:67,427,066...67,473,649
JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in ISO (PMID:16608847) RGD PMID:16608847 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bid BH3 interacting domain death agonist acts_upstream_of_or_within ISO MGI:5428930 (MGI:5662300|PMID:26219591) RGD PMID:26219591 MGI:5662300 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Ccar2 cell cycle and apoptosis regulator 2 involved_in ISO (PMID:23352644) RGD PMID:23352644 NCBI chr15:51,818,887...51,834,443
Ensembl chr15:51,818,897...51,834,030
JBrowse link
G Cdkn2d cyclin dependent kinase inhibitor 2D involved_in ISO (PMID:15750620) RGD PMID:15750620
G Clu clusterin involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:16113678)
BHF-UCL
Ensembl
RGD
PMID:16113678 GO_REF:0000024 GO_REF:0000107 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 involved_in ISO (PMID:20388803) RGD PMID:20388803 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Ddias DNA damage-induced apoptosis suppressor involved_in ISO (PMID:24214091) RGD PMID:24214091 NCBI chr 1:157,675,754...157,700,064
Ensembl chr 1:157,675,765...157,700,064
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 involved_in ISO (PMID:14561758) RGD PMID:14561758 NCBI chr 2:182,723,732...182,731,277
Ensembl chr 2:182,723,854...182,731,764
JBrowse link
G Snai1 snail family transcriptional repressor 1 involved_in ISO (PMID:15314165) RGD PMID:15314165 NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in ISO (PMID:15314165) RGD PMID:15314165 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link
G Tmem161a transmembrane protein 161A involved_in ISO (PMID:16551573) RGD PMID:16551573 NCBI chr16:20,985,841...20,996,351
Ensembl chr16:20,986,687...20,994,379
JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 acts_upstream_of_or_within ISO (PMID:11598139) RGD PMID:11598139 NCBI chr15:57,891,680...57,894,504
Ensembl chr15:57,891,680...57,894,504
JBrowse link
G Trim32 tripartite motif-containing 32 involved_in ISO (PMID:18632609) RGD PMID:18632609 NCBI chr 5:81,431,554...81,449,023
Ensembl chr 5:81,431,600...81,442,451
JBrowse link
G Usp47 ubiquitin specific peptidase 47 acts_upstream_of_or_within ISO MGI:4130032 (MGI:4839431|PMID:19966869) RGD PMID:19966869 MGI:4839431 NCBI chr 1:176,854,589...176,937,763
Ensembl chr 1:176,854,653...176,937,763
JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family, AAA domain containing 5 involved_in ISO (MGI:3584078|PMID:15983387) RGD PMID:15983387 MGI:3584078 NCBI chr10:67,427,042...67,475,825
Ensembl chr10:67,427,066...67,473,649
JBrowse link
G Bcl2l12 BCL2 like 12 acts_upstream_of_or_within ISO (MGI:4834958|PMID:20837658) RGD PMID:20837658 MGI:4834958 NCBI chr 1:100,984,550...100,993,269
Ensembl chr 1:100,984,550...100,993,269
JBrowse link
G Cd44 CD44 molecule (Indian blood group) involved_in IEA
ISO
GO_REF:0000107
(MGI:3690285|PMID:17045821)
(PMID:17045821)
Ensembl
RGD
PMID:17045821 GO_REF:0000107 MGI:3690285 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd74 CD74 molecule involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:3690285|PMID:17045821)
PMID:21873635
(PMID:17045821)
BHF-UCL
RGD
PMID:17045821, PMID:21873635 GO_REF:0000024 MGI:3690285, RGD:13792537 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849
JBrowse link
G Ell3 elongation factor for RNA polymerase II 3 acts_upstream_of_or_within ISO (MGI:5438719|PMID:22768269) RGD PMID:22768269 MGI:5438719 NCBI chr 3:113,400,395...113,405,869
Ensembl chr 3:113,401,734...113,405,829
JBrowse link
G Kdm1a lysine demethylase 1A involved_in ISO (PMID:17805299) RGD PMID:17805299 NCBI chr 5:154,909,003...154,965,171
Ensembl chr 5:154,909,003...154,965,171
JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 involved_in ISS
ISO
GO_REF:0000024
(PMID:29295817)
UniProt
RGD
PMID:29295817 GO_REF:0000024 NCBI chr 3:46,284,961...46,325,230
Ensembl chr 3:46,286,712...46,324,057
JBrowse link
G Mif macrophage migration inhibitory factor involved_in ISO (PMID:17045821) RGD PMID:17045821 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Muc1 mucin 1, cell surface associated involved_in ISO (PMID:15710329) RGD PMID:15710329 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (MGI:2152474|PMID:11672522) RGD PMID:11672522 MGI:2152474 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 involved_in ISO (PMID:15735003) RGD PMID:15735003 NCBI chr12:46,987,404...46,989,906
Ensembl chr12:46,987,404...46,989,897
Ensembl chr12:46,987,404...46,989,897
JBrowse link
G Zfp385a zinc finger protein 385A involved_in ISO (PMID:17719541) RGD PMID:17719541 NCBI chr 7:144,939,616...144,966,364
Ensembl chr 7:144,939,619...144,966,370
JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsph1 heat shock protein family H (Hsp110) member 1 acts_upstream_of_or_within ISO (MGI:3822965|PMID:18681888) RGD PMID:18681888 MGI:3822965 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO
IMP
(PMID:17579517) RGD PMID:17579517, PMID:17579517 RGD:8693356 NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415
JBrowse link
G Trap1 TNF receptor-associated protein 1 involved_in IMP PMID:17579517 ParkinsonsUK-UCL PMID:17579517 RGD:8693356 NCBI chr10:11,724,032...11,757,682
Ensembl chr10:11,724,032...11,757,681
JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:22711822) RGD PMID:22711822 NCBI chr 2:187,964,100...188,022,847
Ensembl chr 2:187,977,008...188,021,377
JBrowse link
G Bdkrb2 bradykinin receptor B2 acts_upstream_of_or_within ISO MGI:1857135 (MGI:3654719|PMID:16571598) RGD PMID:16571598 MGI:3654719 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
JBrowse link
G Epo erythropoietin involved_in ISO (PMID:14569084) RGD PMID:14569084 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Ptger2 prostaglandin E receptor 2 involved_in ISO (PMID:21716255) RGD PMID:21716255 NCBI chr15:19,336,029...19,349,759
Ensembl chr15:19,338,175...19,350,210
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 involved_in ISO (PMID:21716255)
(MGI:5474549|PMID:21716255)
RGD PMID:21716255 MGI:5474549 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ybx3 Y box binding protein 3 involved_in IEA
ISO
GO_REF:0000107
(PMID:22711822)
Ensembl
RGD
PMID:22711822 GO_REF:0000107 NCBI chr 4:165,606,819...165,630,041
Ensembl chr 4:165,606,819...165,630,118
JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb2 bradykinin receptor B2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:98834|MGI:99702 (MGI:3654719|PMID:16571598)
Ensembl
RGD
PMID:16571598 GO_REF:0000107 MGI:3654719 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
JBrowse link
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa2 acetyl-CoA acyltransferase 2 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:18371312)
Ensembl
UniProt
RGD
PMID:18371312 GO_REF:0000024 GO_REF:0000107 NCBI chr18:70,733,872...70,762,395
Ensembl chr18:70,733,872...70,762,395
JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISO (MGI:5796062|PMID:27098698) RGD PMID:27098698 MGI:5796062 NCBI chr 9:100,829,593...100,840,498
Ensembl chr 9:100,829,552...100,840,504
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within ISO MGI:104995 (MGI:3047441|PMID:15288121) RGD PMID:15288121 MGI:3047441 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:20625543) RGD PMID:20625543 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:20625543) RGD PMID:20625543 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within ISO (MGI:4437986|PMID:19096392) RGD PMID:19096392 MGI:4437986 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
JBrowse link
G Mpv17l MPV17 mitochondrial inner membrane protein like involved_in ISO (PMID:22306510) RGD PMID:22306510 NCBI chr10:3,321,488...3,359,219
Ensembl chr10:3,321,476...3,357,470
JBrowse link
G Slc25a5 solute carrier family 25 member 5 involved_in ISS
ISO
GO_REF:0000024
(PMID:19154410)
UniProt
RGD
PMID:19154410 GO_REF:0000024 NCBI chr  X:123,404,570...123,407,637
Ensembl chr  X:123,404,518...123,407,645
JBrowse link
G Slc35f6 solute carrier family 35, member F6 involved_in ISS
ISO
GO_REF:0000024
(PMID:19154410)
UniProt
RGD
PMID:19154410 GO_REF:0000024 NCBI chr 6:27,095,144...27,106,982
Ensembl chr 6:27,095,141...27,107,030
JBrowse link
G Tmem14a transmembrane protein 14A involved_in ISO
IBA
(PMID:21723035)
PMID:21873635
RGD PMID:21723035, PMID:21873635 RGD:13792537 NCBI chr 9:27,333,956...27,345,612
Ensembl chr 9:27,343,853...27,345,070
Ensembl chr 9:27,343,853...27,345,070
JBrowse link
negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 involved_in ISO (PMID:14752510) RGD PMID:14752510 NCBI chr 5:57,028,467...57,039,378
Ensembl chr 5:57,028,467...57,039,378
JBrowse link
G Park7 Parkinsonism associated deglycase involved_in IEA
ISO
GO_REF:0000107
(PMID:14752510)
Ensembl
RGD
PMID:14752510 GO_REF:0000107 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag5 BAG cochaperone 5 involved_in ISO (PMID:24475098) RGD PMID:24475098 NCBI chr 6:136,180,640...136,185,651
Ensembl chr 6:136,182,006...136,185,651
JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2158814 (MGI:3698597|PMID:16373599)
Ensembl
RGD
PMID:16373599 GO_REF:0000107 MGI:3698597 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:3581090|PMID:15731106)
Ensembl
RGD
PMID:15731106 GO_REF:0000107 MGI:3581090 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 involved_in ISO (PMID:23043106) RGD PMID:23043106 NCBI chr10:47,768,592...47,775,130
Ensembl chr10:47,766,680...47,775,055
Ensembl chr10:47,766,680...47,775,055
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 involved_in ISO (PMID:23043106) RGD PMID:23043106 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nme5 NME/NM23 family member 5 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:2664629|PMID:12788088)
RGD PMID:12788088, PMID:21873635 MGI:2664629, RGD:13792537 NCBI chr18:27,357,460...27,374,641
Ensembl chr18:27,357,413...27,374,603
JBrowse link
G Nol3 nucleolar protein 3 involved_in ISO
IEA
(PMID:15004034)
GO_REF:0000107
RGD
Ensembl
PMID:15004034 GO_REF:0000107 NCBI chr19:37,232,567...37,236,668
Ensembl chr19:37,235,001...37,236,649
JBrowse link
G Ppia peptidylprolyl isomerase A involved_in ISO
ISS
(PMID:26095851)
GO_REF:0000024
RGD
UniProt
PMID:26095851 GO_REF:0000024 NCBI chr14:86,673,775...86,677,443
Ensembl chr14:86,673,775...86,677,443
JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr14:22,706,906...22,707,648
Ensembl chr14:22,706,901...22,707,668
JBrowse link
G Sirt1 sirtuin 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:17317627)
Ensembl
RGD
PMID:17317627 GO_REF:0000107 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Sod2 superoxide dismutase 2 involved_in ISO (PMID:12551919) RGD PMID:12551919 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Vnn1 vanin 1 involved_in ISO (MGI:3052282|PMID:15282320) RGD PMID:15282320 MGI:3052282 NCBI chr 1:22,614,832...22,625,134
Ensembl chr 1:22,614,783...22,625,204
JBrowse link
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in ISO
IEA
(PMID:24899725)
GO_REF:0000107
RGD
Ensembl
PMID:24899725 GO_REF:0000107 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Nono non-POU domain containing, octamer-binding involved_in ISO (PMID:15790595) RGD PMID:15790595 NCBI chr  X:71,324,365...71,342,225
Ensembl chr  X:71,324,365...71,342,225
JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO
ISS
(PMID:15790595)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:15790595 GO_REF:0000024 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
ISS
(PMID:17314283)
(MGI:5543313|PMID:23858059)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:17314283 PMID:23858059 GO_REF:0000024 MGI:5543313 NCBI chr 1:48,880,015...50,069,998 JBrowse link
negative regulation of release of cytochrome c from mitochondria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5294538|PMID:18977203)
UniProt
RGD
PMID:18977203 GO_REF:0000024 MGI:5294538 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Arrb2 arrestin, beta 2 IMP RGD PMID:19171933 RGD:5510006 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134
JBrowse link
G Avp arginine vasopressin involved_in ISO (PMID:18402937) RGD PMID:18402937 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Bcl2l2 Bcl2-like 2 IDA RGD PMID:10724126 RGD:14394498 NCBI chr15:33,543,774...33,549,165
Ensembl chr15:33,544,312...33,549,164
JBrowse link
G Fxn frataxin involved_in IEA
ISO
GO_REF:0000107
(PMID:16608849)
Ensembl
RGD
PMID:16608849 GO_REF:0000107 NCBI chr 1:242,123,975...242,152,834
Ensembl chr 1:242,123,975...242,152,834
JBrowse link
G Ghitm growth hormone inducible transmembrane protein involved_in ISO (PMID:18417609) RGD PMID:18417609 NCBI chr16:14,370,269...14,382,647
Ensembl chr16:14,371,531...14,382,641
JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in ISO
IEA
(PMID:12221075)
GO_REF:0000107
RGD
Ensembl
PMID:12221075 GO_REF:0000107 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Hgf hepatocyte growth factor involved_in ISO (PMID:20655899) RGD PMID:20655899 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A acts_upstream_of_or_within ISO (MGI:5306879|PMID:21856340) RGD PMID:21856340 MGI:5306879 NCBI chr 8:130,482,492...130,491,888
Ensembl chr 8:130,482,493...130,491,998
JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5294538|PMID:18977203)
UniProt
RGD
PMID:18977203 GO_REF:0000024 MGI:5294538 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Lmna lamin A/C involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:4879057|PMID:21151901)
Ensembl
RGD
PMID:21151901 GO_REF:0000107 MGI:4879057 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
JBrowse link
G Mfn2 mitofusin 2 IMP RGD PMID:18006463 RGD:12738362 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Nol3 nucleolar protein 3 involved_in IDA
IEA
ISO
PMID:10590251
GO_REF:0000107
(PMID:15004034)
Ensembl
RGD
PMID:15004034, PMID:10590251 GO_REF:0000107, RGD:10047155 NCBI chr19:37,232,567...37,236,668
Ensembl chr19:37,235,001...37,236,649
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISS
ISO
GO_REF:0000024
(MGI:3692706|PMID:16839884)
(PMID:21149567)
ParkinsonsUK-UCL
RGD
PMID:16839884 PMID:21149567 GO_REF:0000024 MGI:3692706 NCBI chr11:74,717,600...74,793,902
Ensembl chr11:74,720,254...74,793,803
JBrowse link
G Pam16 presequence translocase associated motor 16 IDA RGD PMID:24069394 RGD:13462066 NCBI chr10:11,146,359...11,153,936
Ensembl chr10:11,146,359...11,153,936
JBrowse link
G Parl presenilin associated, rhomboid-like involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:3692706|PMID:16839884)
GO_REF:0000024
Ensembl
RGD
ParkinsonsUK-UCL
PMID:16839884 GO_REF:0000024 GO_REF:0000107 MGI:3692706 NCBI chr11:84,517,368...84,544,463
Ensembl chr11:84,517,368...84,544,462
JBrowse link
G Ppif peptidylprolyl isomerase F involved_in ISS
ISO
GO_REF:0000024
(PMID:19228691)
UniProt
RGD
PMID:19228691 GO_REF:0000024 NCBI chr16:1,979,191...1,985,912
Ensembl chr16:1,979,191...1,985,908
JBrowse link
G Prelid1 PRELI domain containing 1 involved_in ISO (PMID:23931759) RGD PMID:23931759 NCBI chr17:9,834,245...9,837,285
Ensembl chr17:9,834,242...9,837,303
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
ISS
(PMID:19880420), (PMID:23453807)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:19880420 PMID:23453807 GO_REF:0000024 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:19729910)
Ensembl
UniProt
RGD
PMID:19729910 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:112,323,188...112,328,642
Ensembl chr  X:112,323,187...112,328,642
JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 involved_in ISO (PMID:23931759) RGD PMID:23931759 NCBI chr12:46,987,404...46,989,906
Ensembl chr12:46,987,404...46,989,897
Ensembl chr12:46,987,404...46,989,897
JBrowse link
negative regulation of TRAIL-activated apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:21785459)
GO_REF:0000107
ParkinsonsUK-UCL
RGD
Ensembl
PMID:21785459 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
positive regulation of apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07025928.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr16:55,834,458...55,835,117 JBrowse link
G AABR07052430.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 3:52,997,922...52,998,650 JBrowse link
G Adora2a adenosine A2a receptor acts_upstream_of_or_within ISO MGI:2155985 (MGI:1860411|PMID:10845921) RGD PMID:10845921 MGI:1860411 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 acts_upstream_of_or_within ISO MGI:1889507 (MGI:3603971|PMID:16183742) RGD PMID:16183742 MGI:3603971 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Bid BH3 interacting domain death agonist acts_upstream_of_or_within ISO (MGI:84156|PMID:8918887) RGD PMID:8918887 MGI:84156 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Bmf Bcl2 modifying factor acts_upstream_of_or_within ISO (MGI:2158578|PMID:11546872) RGD PMID:11546872 MGI:2158578 NCBI chr 3:110,303,515...110,324,125
Ensembl chr 3:110,306,067...110,324,084
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta acts_upstream_of_or_within ISO (MGI:3710042|PMID:17367784) RGD PMID:17367784 MGI:3710042 NCBI chr14:86,208,876...86,297,727
Ensembl chr14:86,208,901...86,297,652
JBrowse link
G Casp2 caspase 2 acts_upstream_of_or_within ISO MGI:1889507 (MGI:3603971|PMID:16183742) RGD PMID:16183742 MGI:3603971 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1889507 (MGI:3603971|PMID:16183742)
RGD PMID:16183742, PMID:21873635 MGI:3603971, RGD:13792537 NCBI chr 7:36,395,665...36,408,588
Ensembl chr 7:36,395,665...36,408,588
JBrowse link
G Ctsc cathepsin C acts_upstream_of_or_within ISO MGI:107285 (MGI:4838939|PMID:20435891) RGD PMID:20435891 MGI:4838939 NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983
JBrowse link
G Ctsh cathepsin H acts_upstream_of_or_within ISO MGI:109553 (MGI:4838939|PMID:20435891) RGD PMID:20435891 MGI:4838939 NCBI chr 8:97,439,155...97,458,293
Ensembl chr 8:97,439,161...97,458,287
JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:19903888)
UniProt
Ensembl
RGD
PMID:19903888 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:14,889,263...15,060,286
Ensembl chr 3:14,889,510...15,060,286
JBrowse link
G Daxx death-domain associated protein acts_upstream_of_or_within ISO MGI:104662 (MGI:4942266|PMID:10684855) RGD PMID:10684855 MGI:4942266 NCBI chr20:5,480,103...5,485,962
Ensembl chr20:5,480,103...5,485,926
JBrowse link
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 acts_upstream_of_or_within ISO MGI:3574590 (MGI:3573962|PMID:15680327) RGD PMID:15680327 MGI:3573962 NCBI chr17:26,785,017...26,795,723
Ensembl chr17:26,785,029...26,797,161
JBrowse link
G Fas Fas cell surface death receptor involved_in ISO (PMID:11096076) RGD PMID:11096076 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Ifnb1 interferon beta 1 involved_in ISO (PMID:10918594), (PMID:11337497) RGD PMID:10918594 PMID:11337497 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Il19 interleukin 19 acts_upstream_of_or_within ISO (MGI:2653146|PMID:12370360) RGD PMID:12370360 MGI:2653146 NCBI chr13:47,663,592...47,677,869
Ensembl chr13:47,664,080...47,670,407
JBrowse link
G Inca1 inhibitor of CDK, cyclin A1 interacting protein 1 acts_upstream_of_or_within ISO UniProtKB:Q8WYH8 (MGI:5287344|PMID:21750715) RGD PMID:21750715 MGI:5287344 NCBI chr10:57,309,722...57,322,140
Ensembl chr10:57,309,972...57,317,985
JBrowse link
G Ing5 inhibitor of growth family, member 5 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2144284 (MGI:5287344|PMID:21750715)
RGD PMID:21750715, PMID:21873635 MGI:5287344, RGD:13792537 NCBI chr 9:100,932,932...100,950,233
Ensembl chr 9:100,932,545...100,952,416
JBrowse link
G Inhbb inhibin subunit beta B involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:98957 (MGI:4454604|PMID:20454446)
Ensembl
RGD
PMID:20454446 GO_REF:0000107 MGI:4454604 NCBI chr13:35,436,532...35,442,222
Ensembl chr13:35,436,532...35,442,222
JBrowse link
G Jak2 Janus kinase 2 acts_upstream_of_or_within ISO (MGI:3036919|PMID:15012602) RGD PMID:15012602 MGI:3036919 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Maged1 MAGE family member D1 acts_upstream_of_or_within ISO MGI:1929608 (MGI:3848096|PMID:19268530), (MGI:4359364|PMID:17488777) RGD PMID:17488777 PMID:19268530 MGI:3848096 MGI:4359364 NCBI chr  X:63,803,194...63,809,715
Ensembl chr  X:63,803,189...63,809,861
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 acts_upstream_of_or_within ISO MGI:1346862 (MGI:3619752|PMID:16458303) RGD PMID:16458303 MGI:3619752 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1346861 (MGI:3619752|PMID:16458303)
Ensembl
RGD
PMID:16458303 GO_REF:0000107 MGI:3619752 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor acts_upstream_of_or_within ISO MGI:2447604 (MGI:2677658|PMID:14517295) RGD PMID:14517295 MGI:2677658 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 acts_upstream_of_or_within ISO (MGI:4829576|PMID:20530871) RGD PMID:20530871 MGI:4829576 NCBI chr15:34,493,163...34,502,238
Ensembl chr15:34,493,138...34,504,326
JBrowse link
G Ngfr nerve growth factor receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:1859527|PMID:10764727)
Ensembl
RGD
PMID:10764727 GO_REF:0000107 MGI:1859527 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Nkx3-1 NK3 homeobox 1 involved_in ISO (PMID:20599703) RGD PMID:20599703 NCBI chr15:51,065,316...51,067,908
Ensembl chr15:51,065,316...51,068,421
JBrowse link
G Osm oncostatin M acts_upstream_of_or_within ISO (MGI:3036919|PMID:15012602) RGD PMID:15012602 MGI:3036919 NCBI chr14:84,457,487...84,469,426
Ensembl chr14:84,465,515...84,470,409
JBrowse link
G Pdcd7 programmed cell death 7 acts_upstream_of_or_within ISO (MGI:1333591|PMID:10037816) RGD PMID:10037816 MGI:1333591 NCBI chr 8:70,860,671...70,875,471
Ensembl chr 8:70,860,671...70,875,471
JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within ISO MGI:1197015 (MGI:4942266|PMID:10684855) RGD PMID:10684855 MGI:4942266 NCBI chr 8:63,002,515...63,034,310
Ensembl chr 8:63,004,870...63,034,226
JBrowse link
G Prkcd protein kinase C, delta involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3581090|PMID:15731106)
Ensembl
RGD
PMID:15731106 GO_REF:0000107 MGI:3581090 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
G Pten phosphatase and tensin homolog acts_upstream_of_or_within ISO MGI:1857937 (MGI:2180890|PMID:9778245) RGD PMID:9778245 MGI:2180890 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G RGD1560831 similar to 40S ribosomal protein S3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:52,997,847...52,998,669 JBrowse link
G Rps3 ribosomal protein S3 involved_in IBA
ISO
PMID:21873635
(PMID:14988002)
RGD PMID:14988002, PMID:21873635 RGD:13792537 NCBI chr 1:164,435,868...164,441,167
Ensembl chr 1:164,435,878...164,441,167
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO (PMID:18758450) RGD PMID:18758450 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 acts_upstream_of_or_within ISO MGI:1336991 (MGI:3612718|PMID:16044147) RGD PMID:16044147 MGI:3612718 NCBI chr 5:24,402,895...24,419,651
Ensembl chr 5:24,410,863...24,416,888
JBrowse link
G Tp63 tumor protein p63 acts_upstream_of_or_within ISO (MGI:1289874|PMID:9774969) RGD PMID:9774969 MGI:1289874 NCBI chr11:78,234,853...78,456,559
Ensembl chr11:78,234,800...78,456,501
JBrowse link
G Tp73 tumor protein p73 acts_upstream_of_or_within ISO PR:Q9QXE4-2 (MGI:3612718|PMID:16044147) RGD PMID:16044147 MGI:3612718 NCBI chr 5:171,355,876...171,415,354
Ensembl chr 5:171,355,876...171,415,354
JBrowse link
G Tpd52l1 TPD52 like 1 involved_in ISO
IBA
(PMID:14761963)
PMID:21873635
RGD PMID:14761963, PMID:21873635 RGD:13792537 NCBI chr 1:28,454,949...28,578,736
Ensembl chr 1:28,454,966...28,576,553
JBrowse link
G Traf7 TNF receptor associated factor 7 involved_in ISO (PMID:15001576) RGD PMID:15001576 NCBI chr10:13,874,444...13,893,090
Ensembl chr10:13,874,456...13,892,997
JBrowse link
G Trim39 tripartite motif-containing 39 involved_in IBA
ISO
PMID:21873635
(PMID:19100260)
RGD PMID:19100260, PMID:21873635 RGD:13792537 NCBI chr20:2,500,691...2,514,546
Ensembl chr20:2,500,689...2,514,546
JBrowse link
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
ISO
GO_REF:0000024
(MGI:5648772|PMID:26015568), (MGI:5796067|PMID:26949185)
UniProt
RGD
PMID:26015568 PMID:26949185 GO_REF:0000024 MGI:5648772 MGI:5796067 NCBI chr 9:100,829,593...100,840,498
Ensembl chr 9:100,829,552...100,840,504
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO MGI:1913418 (MGI:5525071|PMID:22240901) RGD PMID:22240901 MGI:5525071 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO (PMID:14676213)
UniProtKB:O55033 (MGI:5613475|PMID:16835242)
RGD PMID:14676213 PMID:16835242 MGI:5613475 NCBI chr 8:108,787,797...108,847,779
Ensembl chr 8:108,787,798...108,847,779
JBrowse link
G Nck2 NCK adaptor protein 2 involved_in ISO UniProtKB:Q99M51 (MGI:5613475|PMID:16835242) RGD PMID:16835242 MGI:5613475 NCBI chr 9:50,246,767...50,373,307
Ensembl chr 9:50,247,692...50,373,284
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISO (MGI:5619464|PMID:21216966) RGD PMID:21216966 MGI:5619464 NCBI chr18:63,415,298...63,489,240
Ensembl chr18:63,415,306...63,488,027
JBrowse link
G Rnf183 ring finger protein 183 involved_in ISO (PMID:29507230) RGD PMID:29507230 NCBI chr 5:78,283,722...78,292,729
Ensembl chr 5:78,284,879...78,285,451
JBrowse link
G Serinc3 serine incorporator 3 acts_upstream_of_or_within ISO (MGI:2671011|PMID:12486168) RGD PMID:12486168 MGI:2671011 NCBI chr 3:160,018,643...160,038,078
Ensembl chr 3:160,018,646...160,038,078
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (MGI:5607229|PMID:20955178) RGD PMID:20955178 MGI:5607229 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Spop speckle type BTB/POZ protein acts_upstream_of_or_within ISO MGI:102851 (MGI:4836774|PMID:20811152) RGD PMID:20811152 MGI:4836774 NCBI chr10:83,231,187...83,311,987
Ensembl chr10:83,231,238...83,311,592
JBrowse link
positive regulation of extrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen involved_in ISO (PMID:10406457) RGD PMID:10406457 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr2 angiotensin II receptor, type 2 involved_in ISO (PMID:10406457) RGD PMID:10406457 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Bcl10 BCL10, immune signaling adaptor involved_in
acts_upstream_of_or_within
IBA
ISO
ISS
PMID:21873635
(MGI:1355482|PMID:10753917)
GO_REF:0000024
(PMID:11466612)
RGD
UniProt
PMID:10753917 PMID:11466612, PMID:21873635 GO_REF:0000024 MGI:1355482, RGD:13792537 NCBI chr 2:251,805,392...251,814,957
Ensembl chr 2:251,805,392...251,814,957
JBrowse link
G Bcl2l14 BCL2 like 14 involved_in ISO (PMID:11054413) RGD PMID:11054413 NCBI chr 4:168,139,964...168,183,726
Ensembl chr 4:168,142,271...168,183,096
JBrowse link
G Bid BH3 interacting domain death agonist involved_in IBA
ISO
PMID:21873635
(PMID:21459798)
RGD PMID:21459798, PMID:21873635 RGD:13792537 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Casp8 caspase 8 acts_upstream_of_or_within ISO MGI:1889507 (MGI:3603971|PMID:16183742) RGD PMID:16183742 MGI:3603971 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Cav1 caveolin 1 involved_in ISO
IEA
(PMID:21382479)
GO_REF:0000107
RGD
Ensembl
PMID:21382479 GO_REF:0000107 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Cyld CYLD lysine 63 deubiquitinase involved_in IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:21525013)
Ensembl
RGD
PMID:21525013, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr19:19,264,984...19,323,817
Ensembl chr19:19,265,164...19,315,357
JBrowse link
G Dedd2 death effector domain containing 2 involved_in ISO (PMID:11741985) RGD PMID:11741985 NCBI chr 1:82,073,024...82,089,028
Ensembl chr 1:82,072,544...82,088,275
JBrowse link
G Fadd Fas associated via death domain involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1336166|MGI:2154952 (MGI:5486419|PMID:22675671)
(PMID:21525013)
RGD PMID:21525013 PMID:22675671, PMID:21873635 MGI:5486419, RGD:13792537 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G G0s2 G0/G1switch 2 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:19706769)
UniProt
RGD
PMID:19706769, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr13:112,004,140...112,005,052
Ensembl chr13:112,004,140...112,005,052
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in IDA PMID:23907461 UniProt PMID:23907461 RGD:8553942 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G Hyal2 hyaluronidase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3851310|PMID:19366691)
Ensembl
RGD
PMID:19366691 GO_REF:0000107 MGI:3851310 NCBI chr 8:116,324,062...116,328,978
Ensembl chr 8:116,324,040...116,328,978
JBrowse link
G Itm2c integral membrane protein 2C involved_in ISO (MGI:4821078|PMID:14592447) RGD PMID:14592447 MGI:4821078 NCBI chr 9:92,916,469...92,930,306
Ensembl chr 9:92,916,469...92,930,279
JBrowse link
G Ltbr lymphotoxin beta receptor involved_in ISO (PMID:20732415) RGD PMID:20732415 NCBI chr 4:157,822,838...157,829,291
Ensembl chr 4:157,822,840...157,829,241
JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 involved_in ISO (PMID:19240112) RGD PMID:19240112 NCBI chr11:72,829,407...72,865,815
Ensembl chr11:72,829,238...72,865,902
Ensembl chr11:72,829,238...72,865,902
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3578073|PMID:15858817)
Ensembl
RGD
PMID:15858817 GO_REF:0000107 MGI:3578073 NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (PMID:21803845) RGD PMID:21803845 NCBI chr 8:63,002,515...63,034,310
Ensembl chr 8:63,004,870...63,034,226
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:1857277 (MGI:80946|PMID:8666928) RGD PMID:8666928 MGI:80946 NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692
JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:16964285) RGD PMID:16964285 NCBI chr 1:199,438,029...199,439,062
Ensembl chr 1:199,437,832...199,439,210
JBrowse link
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:5000222 (MGI:4437982|PMID:19136968)
Ensembl
RGD
PMID:19136968 GO_REF:0000107 MGI:4437982 NCBI chr 3:147,793,014...147,809,941
Ensembl chr 3:147,793,017...147,809,919
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in
acts_upstream_of_or_within
ISO (PMID:21525013), (PMID:22274400)
MGI:104798 (MGI:5510543|PMID:19498109)
RGD PMID:19498109 PMID:21525013 PMID:22274400 MGI:5510543 NCBI chr17:31,537,580...31,569,904
Ensembl chr17:31,537,591...31,569,904
JBrowse link
G Runx3 RUNX family transcription factor 3 acts_upstream_of_or_within ISO MGI:2179229 (MGI:2177980|PMID:11955451) RGD PMID:11955451 MGI:2177980 NCBI chr 5:153,507,093...153,531,137
Ensembl chr 5:153,507,093...153,531,137
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 acts_upstream_of_or_within ISO MGI:3045799 (MGI:3040721|PMID:14976225) RGD PMID:14976225 MGI:3040721 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777
JBrowse link
G Siglec1 sialic acid binding Ig like lectin 1 acts_upstream_of_or_within ISO MGI:3617694 (MGI:5469747|PMID:23408841) RGD PMID:23408841 MGI:5469747 NCBI chr 3:123,612,067...123,631,718
Ensembl chr 3:123,612,067...123,631,109
JBrowse link
G Tnf tumor necrosis factor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A involved_in IBA
ISO
PMID:21873635
(PMID:21525013)
RGD PMID:21525013, PMID:21873635 RGD:13792537 NCBI chr10:12,995,904...12,997,930
Ensembl chr10:12,995,904...12,997,930
JBrowse link
G Tnfsf10 TNF superfamily member 10 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3576402|PMID:15632112)
(PMID:20097879), (PMID:21525171), (PMID:22266862)
RGD PMID:15632112 PMID:20097879 PMID:21525171 PMID:22266862, PMID:21873635 MGI:3576402, RGD:13792537 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Tnfsf12 TNF superfamily member 12 involved_in ISO (PMID:21525013) RGD PMID:21525013 NCBI chr10:56,290,780...56,300,137
Ensembl chr10:56,290,780...56,300,077
JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in ISO (PMID:21525013) RGD PMID:21525013 NCBI chr 3:2,746,061...2,770,690
Ensembl chr 3:2,746,075...2,770,620
JBrowse link
G Wwox WW domain-containing oxidoreductase involved_in ISO (MGI:3851310|PMID:19366691) RGD PMID:19366691 MGI:3851310 NCBI chr19:46,761,353...47,695,247 JBrowse link
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO (MGI:67275|PMID:8358790) RGD PMID:8358790 MGI:67275 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Ctnna1 catenin alpha 1 acts_upstream_of_or_within ISO MGI:2677796 (MGI:5315030|PMID:22411810) RGD PMID:22411810 MGI:5315030 NCBI chr18:27,923,229...28,055,972
Ensembl chr18:27,923,572...28,055,960
JBrowse link
G Dapk3 death-associated protein kinase 3 involved_in IMP PMID:21172653 UniProt PMID:21172653 RGD:8554227 NCBI chr 7:11,392,436...11,400,855
Ensembl chr 7:11,392,437...11,400,805
JBrowse link
G Htra2 HtrA serine peptidase 2 involved_in ISO (PMID:20125124) RGD PMID:20125124 NCBI chr 4:113,883,671...113,886,833
Ensembl chr 4:113,883,670...113,886,994
JBrowse link
G Inhba inhibin subunit beta A involved_in ISO
ISS
(PMID:8267637)
GO_REF:0000024
RGD
UniProt
PMID:8267637 GO_REF:0000024 NCBI chr17:51,894,869...51,919,998
Ensembl chr17:51,898,217...51,912,496
JBrowse link
G Jak3 Janus kinase 3 involved_in ISO (MGI:3719947|PMID:16020505) RGD PMID:16020505 MGI:3719947 NCBI chr16:20,107,471...20,120,678
Ensembl chr16:20,109,200...20,120,668
JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857478 (MGI:3038547|PMID:15039234)
Ensembl
RGD
PMID:15039234 GO_REF:0000107 MGI:3038547 NCBI chr10:66,732,460...66,928,706
Ensembl chr10:66,690,133...66,928,903
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha acts_upstream_of_or_within ISO (MGI:2183839|PMID:12115603) RGD PMID:12115603 MGI:2183839 NCBI chr 1:219,439,953...219,443,570
Ensembl chr 1:219,439,953...219,443,570
JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha acts_upstream_of_or_within ISO (MGI:2675215|PMID:12944463) RGD PMID:12944463 MGI:2675215 NCBI chr 1:60,717,386...60,736,629
Ensembl chr 1:60,717,386...60,736,609
JBrowse link
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta involved_in ISO (PMID:21172653) RGD PMID:21172653 NCBI chr 8:55,279,278...55,311,768
Ensembl chr 8:55,279,373...55,301,320
JBrowse link
G Ret ret proto-oncogene involved_in ISO (PMID:10921886) RGD PMID:10921886 NCBI chr 4:150,202,170...150,249,196
Ensembl chr 4:150,202,058...150,244,372
JBrowse link
G Srpx sushi-repeat-containing protein, X-linked acts_upstream_of_or_within ISO MGI:3706175 (MGI:3703665|PMID:17088259) RGD PMID:17088259 MGI:3703665 NCBI chr  X:14,146,618...14,220,756
Ensembl chr  X:14,150,038...14,220,662
JBrowse link
G Tgfb2 transforming growth factor, beta 2 acts_upstream_of_or_within ISO (MGI:67124|PMID:8206089) RGD PMID:8206089 MGI:67124 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Unc5b unc-5 netrin receptor B involved_in IMP PMID:21172653 UniProt PMID:21172653 RGD:8554227 NCBI chr20:30,339,680...30,406,593
Ensembl chr20:30,339,673...30,406,295
JBrowse link
G Wwox WW domain-containing oxidoreductase acts_upstream_of_or_within ISO (MGI:3851310|PMID:19366691) RGD PMID:19366691 MGI:3851310 NCBI chr19:46,761,353...47,695,247 JBrowse link
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1b bone morphogenetic protein receptor type 1B acts_upstream_of_or_within ISO MGI:1927616|MGI:95484 (MGI:3819026|PMID:18363966) RGD PMID:18363966 MGI:3819026 NCBI chr 2:247,392,195...247,662,026
Ensembl chr 2:247,403,920...247,446,882
JBrowse link
G Faf1 Fas associated factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:77677|PMID:8524870)
Ensembl
RGD
PMID:8524870 GO_REF:0000107 MGI:77677 NCBI chr 5:129,370,767...129,738,393
Ensembl chr 5:129,448,879...129,738,252
JBrowse link
G Mal mal, T-cell differentiation protein acts_upstream_of_or_within ISO (MGI:3687876|PMID:12776198) RGD PMID:12776198 MGI:3687876 NCBI chr 3:120,209,647...120,233,655
Ensembl chr 3:120,209,647...120,233,655
JBrowse link
G Pea15 proliferation and apoptosis adaptor protein 15 acts_upstream_of_or_within ISO (MGI:3687663|PMID:10588860) RGD PMID:10588860 MGI:3687663 NCBI chr13:90,579,844...90,589,466
Ensembl chr13:90,579,846...90,589,466
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:15705586) RGD PMID:15705586 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO (MGI:84500|PMID:8940094) RGD PMID:8940094 MGI:84500 NCBI chr13:98,513,600...98,539,347
Ensembl chr13:98,513,570...98,530,724
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in ISO
IEA
(PMID:9391078)
GO_REF:0000107
RGD
Ensembl
PMID:9391078 GO_REF:0000107 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777
JBrowse link
G Skil SKI-like proto-oncogene acts_upstream_of_or_within ISO MGI:2387096 (MGI:1858539|PMID:10811619) RGD PMID:10811619 MGI:1858539 NCBI chr 2:115,862,932...115,891,304
Ensembl chr 2:115,866,701...115,891,097
JBrowse link
G Stk3 serine/threonine kinase 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:104798|MGI:1928487|MGI:1929004 (MGI:4420852|PMID:20080598)
Ensembl
RGD
PMID:20080598 GO_REF:0000107 MGI:4420852 NCBI chr 7:73,617,926...73,883,896
Ensembl chr 7:73,618,644...73,883,812
JBrowse link
G Stk4 serine/threonine kinase 4 acts_upstream_of_or_within ISO MGI:104798|MGI:1928487 (MGI:4420852|PMID:20080598) RGD PMID:20080598 MGI:4420852 NCBI chr 3:160,467,552...160,546,540
Ensembl chr 3:160,467,552...160,546,540
JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:18726995) RGD PMID:18726995 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Trps1 transcriptional repressor GATA binding 1 acts_upstream_of_or_within ISO MGI:107191|MGI:95484 (MGI:3819026|PMID:18363966) RGD PMID:18363966 MGI:3819026 NCBI chr 7:90,085,895...90,320,430
Ensembl chr 7:90,090,828...90,318,221
JBrowse link
G Zswim2 zinc finger, SWIM-type containing 2 acts_upstream_of_or_within ISO (MGI:3692348|PMID:16522193) RGD PMID:16522193 MGI:3692348 NCBI chr 3:71,274,341...71,295,641
Ensembl chr 3:71,274,337...71,295,629
JBrowse link
positive regulation of intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within
IEA
ISO
ISS
GO_REF:0000107
MGI:2158306 (MGI:3692043|PMID:14502238)
(PMID:14963330), (PMID:21199865), (PMID:21262771)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:14502238 PMID:14963330 PMID:21199865 PMID:21262771 GO_REF:0000024 GO_REF:0000107 MGI:3692043 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 involved_in IMP
ISS
ISO
PMID:27031958
GO_REF:0000024
(PMID:17289999), (PMID:27031958)
UniProt
RGD
PMID:17289999 PMID:27031958, PMID:27031958 GO_REF:0000024, RGD:14390051 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcap31 B-cell receptor-associated protein 31 involved_in ISO (PMID:21183955) RGD PMID:21183955 NCBI chr  X:157,094,365...157,126,397
Ensembl chr  X:157,095,937...157,126,393
JBrowse link
G Bcl2l11 BCL2 like 11 involved_in ISO (PMID:21671007) RGD PMID:21671007 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 involved_in ISO (PMID:17938203) RGD PMID:17938203 NCBI chr 1:15,799,753...15,828,838
Ensembl chr 1:15,782,477...15,860,624
JBrowse link
G Becn1 beclin 1 involved_in IMP
ISO
ISS
PMID:27031958
(PMID:27031958)
GO_REF:0000024
RGD
UniProt
PMID:27031958, PMID:27031958 GO_REF:0000024, RGD:14390051 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bid BH3 interacting domain death agonist involved_in IBA
ISO
PMID:21873635
(PMID:21262771)
RGD PMID:21262771, PMID:21873635 RGD:13792537 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
ISO
GO_REF:0000024
(MGI:5705719|PMID:23429263)
UniProt
RGD
PMID:23429263 GO_REF:0000024 MGI:5705719 NCBI chr 9:100,829,593...100,840,498
Ensembl chr 9:100,829,552...100,840,504
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase acts_upstream_of_or_within ISO MGI:3793294 (MGI:3790365|PMID:17938250) RGD PMID:17938250 MGI:3790365 NCBI chr 3:120,373,604...120,404,910
Ensembl chr 3:120,373,604...120,404,910
JBrowse link
G Cav1 caveolin 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:21382479)
Ensembl
RGD
PMID:21382479 GO_REF:0000107 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Clu clusterin involved_in ISS
ISO
GO_REF:0000024
(PMID:21567405)
UniProt
RGD
PMID:21567405 GO_REF:0000024 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Cyct cytochrome c, testis acts_upstream_of_or_within ISO (MGI:3652666|PMID:16757556) RGD PMID:16757556 MGI:3652666 NCBI chr 3:63,204,779...63,211,847
Ensembl chr 3:62,818,502...63,211,845
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 involved_in ISS
IEA
IBA
ISO
GO_REF:0000024
GO_REF:0000107
PMID:21873635
(PMID:27031958)
UniProt
Ensembl
RGD
PMID:27031958, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Dnm1l dynamin 1-like involved_in ISO (PMID:20850011) RGD PMID:20850011 NCBI chr11:88,830,968...88,882,271
Ensembl chr11:88,830,957...88,880,198
JBrowse link
G Ei24 EI24, autophagy associated transmembrane protein acts_upstream_of_or_within ISO (MGI:3764759|PMID:17981155) RGD PMID:17981155 MGI:3764759 NCBI chr 8:39,254,883...39,271,238
Ensembl chr 8:39,254,889...39,266,959
JBrowse link
G Fis1 fission, mitochondrial 1 involved_in ISO (PMID:21183955) RGD PMID:21183955 NCBI chr12:22,750,485...22,765,324
Ensembl chr12:22,750,485...22,765,308
JBrowse link
G Flcn folliculin acts_upstream_of_or_within ISO MGI:4348628 (MGI:5050037|PMID:21258407) RGD PMID:21258407 MGI:5050037 NCBI chr10:46,153,185...46,172,331
Ensembl chr10:46,153,188...46,172,309
JBrowse link
G Gsdme gasdermin E involved_in ISO (PMID:21522185) RGD PMID:21522185 NCBI chr 4:79,934,075...79,999,678
Ensembl chr 4:79,934,887...79,989,572
JBrowse link
G Il19 interleukin 19 acts_upstream_of_or_within ISO MGI:3605069 (MGI:5491082|PMID:23468852) RGD PMID:23468852 MGI:5491082 NCBI chr13:47,663,592...47,677,869
Ensembl chr13:47,664,080...47,670,407
JBrowse link
G Il20ra interleukin 20 receptor subunit alpha acts_upstream_of_or_within ISO MGI:1890472 (MGI:5491082|PMID:23468852) RGD PMID:23468852 MGI:5491082 NCBI chr 1:15,180,328...15,222,785
Ensembl chr 1:15,180,328...15,222,785
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase involved_in ISO
IEA
(PMID:16116473)
GO_REF:0000107
RGD
Ensembl
PMID:16116473 GO_REF:0000107 NCBI chr 5:147,750,976...147,779,627
Ensembl chr 5:147,750,973...147,761,983
JBrowse link
G Nkx3-1 NK3 homeobox 1 involved_in ISO
ISS
(PMID:17486276)
GO_REF:0000024
RGD
UniProt
PMID:17486276 GO_REF:0000024 NCBI chr15:51,065,316...51,067,908
Ensembl chr15:51,065,316...51,068,421
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator involved_in ISO
ISS
IMP
(PMID:27031958)
GO_REF:0000024
RGD
UniProt
PMID:27031958, PMID:27031958 GO_REF:0000024, RGD:14390051 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524
JBrowse link
G Plagl2 PLAG1 like zinc finger 2 acts_upstream_of_or_within ISO (MGI:2179174|PMID:11832486) RGD PMID:11832486 MGI:2179174 NCBI chr 3:148,709,564...148,722,777
Ensembl chr 3:148,709,531...148,722,742
JBrowse link
G Plekhf1 pleckstrin homology and FYVE domain containing 1 acts_upstream_of_or_within ISO (MGI:3611133|PMID:16188880) RGD PMID:16188880 MGI:3611133 NCBI chr 1:94,609,041...94,616,565
Ensembl chr 1:94,609,377...94,610,854
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:21454712) RGD PMID:21454712 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
JBrowse link
G Prkra protein activator of interferon induced protein kinase EIF2AK2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:2386461|PMID:12181197)
Ensembl
RGD
PMID:12181197 GO_REF:0000107 MGI:2386461 NCBI chr 3:63,489,081...63,507,918
Ensembl chr 3:63,489,074...63,507,926
JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in ISO (PMID:19767770) RGD PMID:19767770 NCBI chr10:34,149,717...34,155,198
Ensembl chr10:34,149,717...34,155,198
Ensembl chr12:34,149,717...34,155,198
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 acts_upstream_of_or_within ISO (MGI:1345788|PMID:10490590) RGD PMID:10490590 MGI:1345788 NCBI chr15:34,470,796...34,479,741
Ensembl chr15:34,470,796...34,479,741
JBrowse link
G S100a8 S100 calcium binding protein A8 involved_in ISS
ISO
GO_REF:0000024
(PMID:19935772)
UniProt
RGD
PMID:19935772 GO_REF:0000024 NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354
JBrowse link
G S100a9 S100 calcium binding protein A9 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:19935772)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:19935772 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276
JBrowse link
G Septin4 septin 4 involved_in ISO (PMID:21185211) RGD PMID:21185211 NCBI chr10:74,860,068...74,884,196
Ensembl chr10:74,861,714...74,884,196
JBrowse link
G Siah1 siah E3 ubiquitin protein ligase 1 involved_in ISO (PMID:21185211) RGD PMID:21185211 NCBI chr19:21,372,163...21,395,773
Ensembl chr19:21,372,163...21,395,767
JBrowse link
G Slc9a3r1 SLC9A3 regulator 1 involved_in ISO (PMID:20012548) RGD PMID:20012548 NCBI chr10:103,713,045...103,730,145
Ensembl chr10:103,713,045...103,730,145
JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 involved_in ISO
IBA
(PMID:21262771), (PMID:24709986)
PMID:21873635
RGD PMID:21262771 PMID:24709986, PMID:21873635 RGD:13792537 NCBI chr12:23,954,563...23,987,155
Ensembl chr12:23,954,574...23,987,271
JBrowse link
G Taf6 TATA-box binding protein associated factor 6 involved_in ISO (PMID:20096117) RGD PMID:20096117 NCBI chr12:19,320,269...19,328,706
Ensembl chr12:19,320,271...19,328,637
JBrowse link
G Tp53 tumor protein p53 involved_in ISS
ISO
IMP
GO_REF:0000024
(PMID:14963330), (PMID:27031958)
UniProt
RGD
PMID:14963330 PMID:27031958, PMID:27031958 GO_REF:0000024, RGD:14390051 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif5a eukaryotic translation initiation factor 5A involved_in ISO (PMID:15371445) RGD PMID:15371445 NCBI chr10:56,527,075...56,531,615
Ensembl chr10:56,527,085...56,531,483
JBrowse link
G Msx1 msh homeobox 1 involved_in ISO (PMID:15705871) RGD PMID:15705871 NCBI chr14:77,712,262...77,716,061
Ensembl chr14:77,712,240...77,716,059
JBrowse link
G Rpl11 ribosomal protein L11 involved_in ISO (MGI:5883206|PMID:22262176) RGD PMID:22262176 MGI:5883206 NCBI chr 5:154,390,809...154,394,412
Ensembl chr 5:154,388,140...154,394,328
JBrowse link
G Rps7 ribosomal protein S7 involved_in ISO (PMID:17310983) RGD PMID:17310983 NCBI chr 6:47,899,525...47,904,389
Ensembl chr 6:47,899,525...47,904,437
JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 involved_in ISO (MGI:5553386|PMID:24523556) RGD PMID:24523556 MGI:5553386 NCBI chr 2:250,709,812...250,744,216
Ensembl chr 2:250,709,439...250,744,196
JBrowse link
G Ubb ubiquitin B acts_upstream_of_or_within ISO (PMID:17571083) RGD PMID:17571083 NCBI chr10:48,880,231...48,881,896
Ensembl chr10:48,881,049...48,881,881
JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbh1 F-box DNA helicase 1 acts_upstream_of_or_within ISO (PMID:23361013) RGD PMID:23361013 NCBI chr17:70,399,093...70,437,151
Ensembl chr17:70,399,049...70,437,144
JBrowse link
G Mtch2 mitochondrial carrier 2 acts_upstream_of_or_within ISO MGI:2449949|MGI:5566664 (MGI:5662300|PMID:26219591) RGD PMID:26219591 MGI:5662300 NCBI chr 3:79,678,141...79,695,356
Ensembl chr 3:79,678,201...79,694,006
JBrowse link
G Nacc2 NACC family member 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:22926524)
Ensembl
RGD
PMID:22926524 GO_REF:0000107 NCBI chr 3:3,508,084...3,574,787
Ensembl chr 3:3,510,041...3,574,787
JBrowse link
G Pias4 protein inhibitor of activated STAT, 4 acts_upstream_of_or_within ISO (MGI:5009403|PMID:16816390) RGD PMID:16816390 MGI:5009403 NCBI chr 7:11,414,565...11,428,090
Ensembl chr 7:11,414,446...11,428,552
JBrowse link
G Plscr1 phospholipid scramblase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5284813|PMID:12509439)
Ensembl
RGD
PMID:12509439 GO_REF:0000107 MGI:5284813 NCBI chr 8:99,625,523...99,645,882
Ensembl chr 8:99,625,545...99,725,217
JBrowse link
G Rad9a RAD9 checkpoint clamp component A acts_upstream_of_or_within ISO MGI:2442925 (MGI:3584078|PMID:15983387) RGD PMID:15983387 MGI:3584078 NCBI chr 1:219,443,347...219,450,574
Ensembl chr 1:219,444,092...219,450,451
JBrowse link
G Rps3 ribosomal protein S3 involved_in ISO (PMID:22510408) RGD PMID:22510408 NCBI chr 1:164,435,868...164,441,167
Ensembl chr 1:164,435,878...164,441,167
JBrowse link
G Skil SKI-like proto-oncogene acts_upstream_of_or_within ISO MGI:2387096 (MGI:1858539|PMID:10811619) RGD PMID:10811619 MGI:1858539 NCBI chr 2:115,862,932...115,891,304
Ensembl chr 2:115,866,701...115,891,097
JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpl26 ribosomal protein L26 involved_in ISO (PMID:16213212)
(MGI:5882892|PMID:16213212)
RGD PMID:16213212 MGI:5882892 NCBI chr10:55,492,417...55,495,547
Ensembl chr10:55,492,404...55,496,012
JBrowse link
G Steap3 STEAP3 metalloreductase acts_upstream_of_or_within ISO MGI:4398911 (MGI:4367682|PMID:18617898) RGD PMID:18617898 MGI:4367682 NCBI chr13:36,257,220...36,274,144
Ensembl chr13:36,257,112...36,290,531
JBrowse link
G Tp73 tumor protein p73 acts_upstream_of_or_within ISO MGI:2442925|MGI:98834 (MGI:3584078|PMID:15983387) RGD PMID:15983387 MGI:3584078 NCBI chr 5:171,355,876...171,415,354
Ensembl chr 5:171,355,876...171,415,354
JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death involved_in ISO (PMID:21716255)
(MGI:5474549|PMID:21716255)
RGD PMID:21716255 MGI:5474549 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nox1 NADPH oxidase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3616995 (MGI:4881403|PMID:19661248)
Ensembl
RGD
PMID:19661248 GO_REF:0000107 MGI:4881403 NCBI chr  X:104,909,328...104,932,508
Ensembl chr  X:104,909,326...104,932,508
JBrowse link
G Park7 Parkinsonism associated deglycase acts_upstream_of_or_within ISO (MGI:5543357|PMID:22555455) RGD PMID:22555455 MGI:5543357 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Sfpq splicing factor proline and glutamine rich involved_in ISO (PMID:15790595) RGD PMID:15790595 NCBI chr 5:145,079,803...145,088,517
Ensembl chr 5:145,079,803...145,088,498
JBrowse link
G Sod1 superoxide dismutase 1 involved_in ISO (PMID:12551919) RGD PMID:12551919 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:23858059)
(MGI:5543313|PMID:23858059)
RGD PMID:23858059 MGI:5543313 NCBI chr 2:184,230,191...184,309,805
Ensembl chr 2:184,231,260...184,309,664
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in ISO UniProtKB:Q9WVS6 (PMID:23858059)
(MGI:5543313|PMID:23858059)
RGD PMID:23858059 MGI:5543313 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Ralbp1 ralA binding protein 1 IMP RGD PMID:23788031 RGD:12904719 NCBI chr 9:113,579,107...113,598,477
Ensembl chr 9:113,579,107...113,598,480
JBrowse link
positive regulation of TRAIL-activated apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf3 activating transcription factor 3 involved_in ISO (PMID:24939851) RGD PMID:24939851 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (PMID:19962668) RGD PMID:19962668 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 involved_in ISO
IEA
(PMID:19962668)
GO_REF:0000107
RGD
Ensembl
PMID:19962668 GO_REF:0000107 NCBI chr 7:23,543,125...23,594,170
Ensembl chr 7:23,544,215...23,594,133
JBrowse link
regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISO (PMID:23000344) RGD PMID:23000344 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Erp29 endoplasmic reticulum protein 29 involved_in ISO (MGI:5613446|PMID:24370996) RGD PMID:24370996 MGI:5613446 NCBI chr12:40,619,377...40,625,884
Ensembl chr12:40,619,377...40,625,883
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in ISO (MGI:5613477|PMID:15147274) RGD PMID:15147274 MGI:5613477 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254
JBrowse link
regulation of extrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl5 acyl-CoA synthetase long-chain family member 5 involved_in ISO (PMID:17681178) RGD PMID:17681178 NCBI chr 1:276,240,703...276,290,012
Ensembl chr 1:276,240,703...276,290,008
JBrowse link
G Bcl2l12 BCL2 like 12 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:100,984,550...100,993,269
Ensembl chr 1:100,984,550...100,993,269
JBrowse link
G Bcl2l14 BCL2 like 14 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:168,139,964...168,183,726
Ensembl chr 4:168,142,271...168,183,096
JBrowse link
G Dbh dopamine beta-hydroxylase involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857556 (MGI:3587974|PMID:15849236)
Ensembl
RGD
PMID:15849236 GO_REF:0000107 MGI:3587974 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Deptor DEP domain containing MTOR-interacting protein involved_in ISO (PMID:19446321) RGD PMID:19446321 NCBI chr 7:94,795,161...95,000,750
Ensembl chr 7:94,795,214...94,995,809
JBrowse link
G Madd MAP-kinase activating death domain involved_in ISO (PMID:11577081) RGD PMID:11577081 NCBI chr 3:79,960,301...80,003,023
Ensembl chr 3:79,960,301...80,003,032
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO (MGI:72948|PMID:7743522) RGD PMID:7743522 MGI:72948 NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692
JBrowse link
G Traf1 TNF receptor-associated factor 1 involved_in ISO (PMID:10692572) RGD PMID:10692572 NCBI chr 3:14,003,340...14,022,955
Ensembl chr 3:14,003,340...14,022,672
JBrowse link
regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO MGI:2176216|MGI:2181474 (MGI:3608262|PMID:16207751), (MGI:3775898|PMID:18191119) RGD PMID:16207751 PMID:18191119 MGI:3608262 MGI:3775898 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
regulation of extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fem1b fem-1 homolog B involved_in ISO (PMID:10542291) RGD PMID:10542291 NCBI chr 8:67,695,041...67,708,313
Ensembl chr 8:67,694,904...67,708,304
JBrowse link
G Lgals3 galectin 3 involved_in IEA
ISO
GO_REF:0000107
(PMID:8692888)
Ensembl
RGD
PMID:8692888 GO_REF:0000107 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Madd MAP-kinase activating death domain involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:9115275)
UniProt
Ensembl
RGD
PMID:9115275 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:79,960,301...80,003,023
Ensembl chr 3:79,960,301...80,003,032
JBrowse link
G Sp100 SP100 nuclear antigen involved_in ISO (PMID:17245429) RGD PMID:17245429 NCBI chr 9:92,675,103...92,718,489
Ensembl chr 9:92,681,078...92,717,929
JBrowse link
G Stx4 syntaxin 4 involved_in ISO
IEA
(PMID:20956541)
GO_REF:0000107
RGD
Ensembl
PMID:20956541 GO_REF:0000107 NCBI chr 1:199,287,384...199,295,606
Ensembl chr 1:199,287,710...199,294,979
JBrowse link
G Tmc8 transmembrane channel-like 8 involved_in ISO (PMID:23429285) RGD PMID:23429285 NCBI chr10:106,784,819...106,795,307
Ensembl chr10:106,785,077...106,795,299
JBrowse link
regulation of intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyld CYLD lysine 63 deubiquitinase involved_in ISO
IEA
IBA
(PMID:21525013)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:21525013, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr19:19,264,984...19,323,817
Ensembl chr19:19,265,164...19,315,357
JBrowse link
G Dapk2 death-associated protein kinase 2 involved_in ISO (PMID:10376525) RGD PMID:10376525 NCBI chr 8:71,822,107...71,941,941
Ensembl chr 8:71,822,129...71,941,910
JBrowse link
G Ptpmt1 protein tyrosine phosphatase, mitochondrial 1 involved_in IEA
ISO
GO_REF:0000107
UniProtKB:Q9Y6J8 (PMID:24709986)
Ensembl
RGD
PMID:24709986 GO_REF:0000107 NCBI chr 3:79,734,961...79,743,737
Ensembl chr 3:79,734,961...79,743,737
JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:14730312) RGD PMID:14730312 NCBI chr 1:199,438,029...199,439,062
Ensembl chr 1:199,437,832...199,439,210
JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 involved_in ISO UniProtKB:Q8WUK0 (PMID:24709986) RGD PMID:24709986 NCBI chr12:23,954,563...23,987,155
Ensembl chr12:23,954,574...23,987,271
JBrowse link
regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd2 ankyrin repeat domain 2 acts_upstream_of_or_within ISO (MGI:3796961|PMID:18302940) RGD PMID:18302940 MGI:3796961 NCBI chr 1:261,281,859...261,291,307
Ensembl chr 1:261,281,543...261,291,394
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO (MGI:3818156|PMID:17571083) RGD PMID:17571083 MGI:3818156 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnrnpk heterogeneous nuclear ribonucleoprotein K involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:4881379|PMID:20673990)
Ensembl
RGD
PMID:20673990 GO_REF:0000107 MGI:4881379 NCBI chr17:6,664,730...6,676,753
Ensembl chr17:6,665,659...6,676,654
JBrowse link
regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P4hb prolyl 4-hydroxylase subunit beta involved_in ISO (PMID:12095988) RGD PMID:12095988 NCBI chr10:109,736,459...109,748,070
Ensembl chr10:109,736,458...109,747,987
JBrowse link
G Ubqln1 ubiquilin 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:12095988)
GO_REF:0000107
BHF-UCL
RGD
Ensembl
PMID:12095988 GO_REF:0000024 GO_REF:0000107 NCBI chr17:6,840,441...6,878,842
Ensembl chr17:6,840,463...6,878,844
JBrowse link
regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp1 poly (ADP-ribose) polymerase 1 IMP RGD PMID:17347665 RGD:10414071 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 acts_upstream_of_or_within ISO (PMID:30684126) RGD PMID:30684126 NCBI chr 9:14,611,541...14,618,076
Ensembl chr 9:14,611,561...14,618,013
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    response to stimulus 10435
      regulation of response to stimulus 3981
        regulation of signal transduction 2963
          regulation of apoptotic signaling pathway 408
            negative regulation of apoptotic signaling pathway + 245
            positive regulation of apoptotic signaling pathway + 160
            regulation of extrinsic apoptotic signaling pathway + 169
            regulation of intrinsic apoptotic signaling pathway + 183
Path 2
Term Annotations click to browse term
  biological_process 19612
    biological regulation 13583
      regulation of biological process 12857
        regulation of cellular process 12354
          regulation of cell death 1760
            regulation of programmed cell death 1585
              regulation of apoptotic process 1549
                regulation of apoptotic signaling pathway 408
                  negative regulation of apoptotic signaling pathway + 245
                  positive regulation of apoptotic signaling pathway + 160
                  regulation of extrinsic apoptotic signaling pathway + 169
                  regulation of intrinsic apoptotic signaling pathway + 183
paths to the root