Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of apoptotic signaling pathway
go back to main search page
Accession:GO:2001233 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of apoptotic signaling pathway.
Synonyms:exact_synonym: regulation of apoptotic signalling pathway



show annotations for term's descendants           Sort by:
 
regulation of apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp8 caspase 8 acts_upstream_of_or_within ISO MGI:103223 (MGI:3056854|PMID:15456877) RGD PMID:15456877 MGI:3056854 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Pmp22 peripheral myelin protein 22 acts_upstream_of_or_within ISO MGI:1856217 (MGI:5517729|PMID:23847051) RGD PMID:23847051 MGI:5517729 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
JBrowse link
G Ppia peptidylprolyl isomerase A involved_in ISS
ISO
GO_REF:0000024
(PMID:23180369)
UniProt
RGD
PMID:23180369 GO_REF:0000024 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr14:21,006,522...21,007,284
Ensembl chr14:21,006,538...21,007,310
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor acts_upstream_of_or_within ISO MGI:1261423 (MGI:3056854|PMID:15456877) RGD PMID:15456877 MGI:3056854 NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377
JBrowse link
negative regulation of apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aatf apoptosis antagonizing transcription factor acts_upstream_of_or_within ISO MGI:1930187 (MGI:4359364|PMID:17488777) RGD PMID:17488777 MGI:4359364 NCBI chr10:69,299,029...69,392,207
Ensembl chr10:69,299,037...69,392,201
JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in ISO
ISS
(PMID:15946935)
GO_REF:0000024
RGD
UniProt
PMID:15946935 GO_REF:0000024 NCBI chr 1:229,865,662...229,973,253
Ensembl chr 1:229,865,662...229,939,162
JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO MGI:2675387 (MGI:3796786|PMID:18436203) RGD PMID:18436203 MGI:3796786 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in
acts_upstream_of_or_within
ISO (PMID:20097879)
(MGI:2158578|PMID:11546872)
RGD PMID:11546872 PMID:20097879 MGI:2158578 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bdnf brain-derived neurotrophic factor involved_in ISO RNAcentral:URS000055128B_10090 (MGI:6295053|PMID:26708520) RGD PMID:26708520 MGI:6295053 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Bmf Bcl2 modifying factor acts_upstream_of_or_within ISO (MGI:2158578|PMID:11546872) RGD PMID:11546872 MGI:2158578 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger acts_upstream_of_or_within ISO MGI:99161 (MGI:1932296|PMID:11290297) RGD PMID:11290297 MGI:1932296 NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690
JBrowse link
G Cdk11b cyclin-dependent kinase 11B involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3043373 (MGI:3041915|PMID:15060143)
Ensembl
RGD
PMID:15060143 GO_REF:0000107 MGI:3041915 NCBI chr 5:166,212,761...166,238,883
Ensembl chr 5:166,212,829...166,238,876
JBrowse link
G Cth cystathionine gamma-lyase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5304595|PMID:22244329)
GO_REF:0000107
RGD
Ensembl
PMID:22244329 GO_REF:0000107 MGI:5304595 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:1858008|MGI:2148567|MGI:98957 (MGI:3051737|PMID:15131783), (MGI:4454604|PMID:20454446)
GO_REF:0000107
RGD
Ensembl
PMID:15131783 PMID:20454446 GO_REF:0000107 MGI:3051737 MGI:4454604 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in ISO UniProtKB:P35411 (PMID:10869418) RGD PMID:10869418 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in IGI PMID:10869418 ARUK-UCL PMID:10869418 RGD:4892026 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:4888719 (MGI:4880811|PMID:21209208)
PMID:21873635
RGD PMID:21209208 PMID:21873635 MGI:4880811, RGD:13792537 NCBI chr 7:130,632,368...130,659,353
Ensembl chr 7:130,633,348...130,659,168
JBrowse link
G Gata4 GATA binding protein 4 involved_in ISO (MGI:5780531|PMID:25590961) RGD PMID:25590961 MGI:5780531 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636
JBrowse link
G Gnai2 G protein subunit alpha i2 IMP RGD PMID:25633408 RGD:13507311 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
JBrowse link
G Gnai3 G protein subunit alpha i3 IMP RGD PMID:25633408 RGD:13507311 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742
JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:107,962,194...107,965,368
Ensembl chr 7:107,962,207...107,965,366
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 acts_upstream_of_or_within ISO (MGI:3581090|PMID:15731106) RGD PMID:15731106 MGI:3581090 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 acts_upstream_of_or_within ISO (MGI:3688933|PMID:16857185) RGD PMID:16857185 MGI:3688933 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Igbp1 immunoglobulin binding protein 1 acts_upstream_of_or_within ISO MGI:2448686|MGI:3056510 (MGI:3056248|PMID:15499020) RGD PMID:15499020 MGI:3056248 NCBI chr  X:65,582,832...65,605,078
Ensembl chr  X:65,582,821...65,606,049
JBrowse link
G Ing2 inhibitor of growth family, member 2 acts_upstream_of_or_within ISO MGI:4879096 (MGI:4867787|PMID:21124965) RGD PMID:21124965 MGI:4867787 NCBI chr16:44,573,592...44,584,180
Ensembl chr16:44,575,597...44,583,482
JBrowse link
G Madd MAP-kinase activating death domain acts_upstream_of_or_within ISO (MGI:3700423|PMID:14735464) RGD PMID:14735464 MGI:3700423 NCBI chr 3:77,114,330...77,157,865
Ensembl chr 3:77,114,314...77,157,701
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 acts_upstream_of_or_within ISO MGI:104798 (MGI:3607973|PMID:16260493) RGD PMID:16260493 MGI:3607973 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 involved_in ISO (PMID:10756100) RGD PMID:10756100 NCBI chr 7:120,526,732...120,536,982
Ensembl chr 7:120,526,732...120,536,982
JBrowse link
G Maz MYC associated zinc finger protein involved_in ISO (PMID:25487955) RGD PMID:25487955 NCBI chr 1:181,629,742...181,635,193
Ensembl chr 1:181,629,729...181,650,408
JBrowse link
G Meis3 Meis homeobox 3 acts_upstream_of_or_within ISO (MGI:4848231|PMID:21059917) RGD PMID:21059917 MGI:4848231 NCBI chr 1:76,861,267...76,872,691
Ensembl chr 1:76,861,924...76,872,691
JBrowse link
G Mir210 microRNA 210 involved_in ISO (PMID:26780211) RGD PMID:26780211 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454
JBrowse link
G Mnt MAX network transcriptional repressor acts_upstream_of_or_within ISO MGI:2678322 (MGI:2675510|PMID:12970171) RGD PMID:12970171 MGI:2675510 NCBI chr10:59,699,208...59,714,848
Ensembl chr10:59,699,585...59,714,835
JBrowse link
G Mrtfa myocardin related transcription factor A acts_upstream_of_or_within ISO (MGI:2183867|PMID:12019265) RGD PMID:12019265 MGI:2183867 NCBI chr 7:112,544,312...112,714,431
Ensembl chr 7:112,544,312...112,714,418
JBrowse link
G Nanos3 nanos C2HC-type zinc finger 3 acts_upstream_of_or_within ISO MGI:2682607|MGI:99702 (MGI:3796786|PMID:18436203) RGD PMID:18436203 MGI:3796786 NCBI chr19:23,978,465...23,988,933
Ensembl chr19:23,985,504...23,988,932
JBrowse link
G Nog noggin involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1862000 (MGI:3640733|PMID:16712836)
Ensembl
RGD
PMID:16712836 GO_REF:0000107 MGI:3640733 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 involved_in ISO
IEA
(PMID:19429166)
GO_REF:0000107
RGD
Ensembl
PMID:19429166 GO_REF:0000107 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Pam16 presequence translocase associated motor 16 acts_upstream_of_or_within ISO (MGI:4837988|PMID:20719856) RGD PMID:20719856 MGI:4837988 NCBI chr10:10,942,534...10,950,654
Ensembl chr10:10,943,001...10,950,649
JBrowse link
G Pcgf2 polycomb group ring finger 2 acts_upstream_of_or_within ISO MGI:88174 (MGI:1932296|PMID:11290297) RGD PMID:11290297 MGI:1932296 NCBI chr10:82,682,563...82,694,563
Ensembl chr10:82,683,553...82,693,406
JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within ISO MGI:109284 (MGI:3044464|PMID:15148382) RGD PMID:15148382 MGI:3044464 NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO MGI:1202717 (MGI:3044464|PMID:15148382) RGD PMID:15148382 MGI:3044464 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174
JBrowse link
G Qars1 glutaminyl-tRNA synthetase 1 involved_in ISO (PMID:11096076) RGD PMID:11096076 NCBI chr 8:109,207,705...109,215,738
Ensembl chr 8:109,207,705...109,215,739
JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in IMP PMID:24027266 ARUK-UCL PMID:24027266 RGD:14397580 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Tmbim1 transmembrane BAX inhibitor motif containing 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:75,871,835...75,889,366
Ensembl chr 9:75,871,835...75,889,069
JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO
IBA
(PMID:21075086)
PMID:21873635
RGD PMID:21075086 PMID:21873635 RGD:13792537 NCBI chr 7:130,512,428...130,543,637
Ensembl chr 7:130,527,316...130,543,633
JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO RNAcentral:URS0000330617_9606 (PMID:31124343) RGD PMID:31124343 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Wnt4 Wnt family member 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:88276|MGI:96571 (MGI:4454604|PMID:20454446)
Ensembl
RGD
PMID:20454446 GO_REF:0000107 MGI:4454604 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859
JBrowse link
negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Caap1 caspase activity and apoptosis inhibitor 1 involved_in ISO
IBA
(PMID:21980415)
PMID:21873635
RGD PMID:21980415 PMID:21873635 RGD:13792537 NCBI chr 5:109,313,253...109,414,323
Ensembl chr 5:109,361,912...109,414,314
JBrowse link
G Il9 interleukin 9 acts_upstream_of_or_within ISO MGI:96564 (MGI:4367548|PMID:18551134) RGD PMID:18551134 MGI:4367548 NCBI chr17:8,111,772...8,114,895
Ensembl chr17:8,111,772...8,114,895
JBrowse link
G Il9r interleukin 9 receptor acts_upstream_of_or_within ISO MGI:3589948|MGI:96563 (MGI:4367548|PMID:18551134) RGD PMID:18551134 MGI:4367548 NCBI chr10:15,431,706...15,444,144
Ensembl chr10:15,431,706...15,441,990
JBrowse link
G Mmp9 matrix metallopeptidase 9 involved_in IEA
ISO
GO_REF:0000107
(PMID:22984561)
Ensembl
RGD
PMID:22984561 GO_REF:0000107 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Nle1 notchless homolog 1 acts_upstream_of_or_within ISO MGI:2671871|MGI:2671874 (MGI:5468737|PMID:23231322) RGD PMID:23231322 MGI:5468737 NCBI chr10:67,834,059...67,844,771
Ensembl chr10:67,834,062...67,842,658
JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISS
ISO
GO_REF:0000024
(PMID:21785459)
ParkinsonsUK-UCL
RGD
PMID:21785459 GO_REF:0000024 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Pih1d1 PIH1 domain containing 1 involved_in ISO (PMID:21078300) RGD PMID:21078300 NCBI chr 1:95,639,597...95,645,295
Ensembl chr 1:95,639,592...95,645,290
JBrowse link
G Plaur plasminogen activator, urokinase receptor involved_in ISO (PMID:22984561) RGD PMID:22984561 NCBI chr 1:80,053,441...80,068,384
Ensembl chr 1:80,050,324...80,068,595
JBrowse link
negative regulation of death-inducing signaling complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nol3 nucleolar protein 3 involved_in IDA PMID:12191471
PMID:15383280
UniProt PMID:12191471 PMID:15383280 RGD:631884, RGD:10047289 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2l1 Bcl2-like 1 involved_in ISO
ISS
(PMID:29507230)
GO_REF:0000024
RGD
UniProt
PMID:29507230 GO_REF:0000024 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Creb3 cAMP responsive element binding protein 3 involved_in ISO (PMID:16940180) RGD PMID:16940180 NCBI chr 5:57,817,835...57,823,171
Ensembl chr 5:57,817,832...57,824,390
JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 involved_in IMP
ISO
PMID:15665855
(MGI:5616321|PMID:15665855)
RGD PMID:15665855 PMID:15665855 MGI:5616321, RGD:1558627 NCBI chr 3:77,952,589...77,993,513
Ensembl chr 3:77,952,540...77,993,456
JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 acts_upstream_of_or_within ISO MGI:1341830|MGI:99682 (MGI:5525071|PMID:22240901) RGD PMID:22240901 MGI:5525071 NCBI chr 7:107,962,194...107,965,368
Ensembl chr 7:107,962,207...107,965,366
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in ISO
IBA
(PMID:15102845)
PMID:21873635
RGD PMID:15102845 PMID:21873635 RGD:13792537 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:12150907), (PMID:20625543) RGD PMID:12150907 PMID:20625543
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:12150907), (PMID:20625543) RGD PMID:12150907 PMID:20625543 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in ISO (MGI:5495588|PMID:23453807) RGD PMID:23453807 MGI:5495588 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:21857923) RGD PMID:21857923 NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Ngf nerve growth factor involved_in NAS PMID:21266243 ParkinsonsUK-UCL PMID:21266243 RGD:10047230 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISS
ISO
GO_REF:0000024
(MGI:5495588|PMID:23453807)
UniProtKB:P58281 (PMID:23453807)
ParkinsonsUK-UCL
RGD
PMID:23453807 GO_REF:0000024 MGI:5495588 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO UniProtKB:Q99LX0 (PMID:14652021)
(MGI:5613479|PMID:14652021)
RGD PMID:14652021 MGI:5613479 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 acts_upstream_of_or_within ISO MGI:2181360 (MGI:4836774|PMID:20811152) RGD PMID:20811152 MGI:4836774 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISS
ISO
GO_REF:0000024
(MGI:5433837|PMID:21113145)
(PMID:10973942), (PMID:11439185), (PMID:12150907), (PMID:21113145), (PMID:23453807)
ParkinsonsUK-UCL
RGD
PMID:10973942 PMID:11439185 PMID:12150907 PMID:21113145 PMID:23453807 GO_REF:0000024 MGI:5433837 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO (MGI:5619464|PMID:21216966) RGD PMID:21216966 MGI:5619464 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504
JBrowse link
G Selenos selenoprotein S involved_in ISO
IEA
(PMID:17210132)
GO_REF:0000107
RGD
Ensembl
PMID:17210132 GO_REF:0000107 NCBI chr 1:119,659,779...119,669,546
Ensembl chr 1:119,659,751...119,669,833
JBrowse link
G Syvn1 synoviolin 1 involved_in
acts_upstream_of_or_within
ISO (PMID:12459480), (PMID:17059562)
MGI:2679656 (MGI:3575050|PMID:15611074)
RGD PMID:12459480 PMID:15611074 PMID:17059562 MGI:3575050 NCBI chr 1:203,339,235...203,346,137
Ensembl chr 1:203,339,619...203,346,152
JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in
acts_upstream_of_or_within
ISO (PMID:21075086)
MGI:1913418 (MGI:5525071|PMID:22240901)
RGD PMID:21075086 PMID:22240901 MGI:5525071 NCBI chr 7:130,512,428...130,543,637
Ensembl chr 7:130,527,316...130,543,633
JBrowse link
G Txndc12 thioredoxin domain containing 12 acts_upstream_of_or_within ISO (PMID:18628206) RGD PMID:18628206 NCBI chr 5:123,587,854...123,612,886
Ensembl chr 5:123,586,781...123,612,870
JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in ISO (MGI:3629256|PMID:16571599) RGD PMID:16571599 MGI:3629256 NCBI chr14:73,810,478...73,834,993
Ensembl chr14:73,810,404...73,835,602
JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO
IEA
IMP
(PMID:19135031)
GO_REF:0000107
PMID:20625543
RGD
Ensembl
PMID:19135031 PMID:20625543 GO_REF:0000107, RGD:10047191 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hyou1 hypoxia up-regulated 1 involved_in ISO (MGI:3697528|PMID:17116640) RGD PMID:17116640 MGI:3697528 NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO UniProtKB:O15354 (MGI:3697528|PMID:17116640), (MGI:5495588|PMID:23453807) RGD PMID:17116640 PMID:23453807 MGI:3697528 MGI:5495588 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
negative regulation of extrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO (PMID:9884026) RGD PMID:9884026 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241
JBrowse link
G Ar androgen receptor involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:21310825)
Ensembl
UniProt
RGD
PMID:21310825 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Birc6 baculoviral IAP repeat-containing 6 involved_in ISO (PMID:14765125) RGD PMID:14765125 NCBI chr 6:20,722,922...20,916,396
Ensembl chr 6:20,722,922...20,916,434
JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO
GO_REF:0000107
(MGI:3039210|PMID:15070745)
Ensembl
RGD
PMID:15070745 GO_REF:0000107 MGI:3039210 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator involved_in
acts_upstream_of_or_within
ISO (PMID:22266862), (PMID:9208847)
MGI:109324|MGI:2154952 (MGI:5486419|PMID:22675671)
RGD PMID:9208847 PMID:22266862 PMID:22675671 MGI:5486419 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Cttn cortactin acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:1924375 (MGI:5437589|PMID:22660580)
GO_REF:0000107
RGD
Ensembl
PMID:22660580 GO_REF:0000107 MGI:5437589 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164
JBrowse link
G Dab2 DAB adaptor protein 2 acts_upstream_of_or_within ISO (MGI:5442513|PMID:15734730) RGD PMID:15734730 MGI:5442513 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
JBrowse link
G Fcmr Fc mu receptor acts_upstream_of_or_within ISO (MGI:3576402|PMID:15632112) RGD PMID:15632112 MGI:3576402 NCBI chr13:42,337,363...42,351,706
Ensembl chr13:42,337,414...42,351,653
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within ISO MGI:104995 (MGI:3047441|PMID:15288121) RGD PMID:15288121 MGI:3047441 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit acts_upstream_of_or_within ISO MGI:104990 (MGI:3047441|PMID:15288121) RGD PMID:15288121 MGI:3047441 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISO (PMID:16636664) RGD PMID:16636664 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Htt huntingtin involved_in ISO
IEA
(PMID:19240112)
GO_REF:0000107
RGD
Ensembl
PMID:19240112 GO_REF:0000107 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070
JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA
IDA
(PMID:16942485)
GO_REF:0000107
PMID:17023532
RGD
Ensembl
PMID:16942485 PMID:17023532 GO_REF:0000107, RGD:1600072 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Il19 interleukin 19 acts_upstream_of_or_within ISO (MGI:5491082|PMID:23468852) RGD PMID:23468852 MGI:5491082 NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473
JBrowse link
G Il4 interleukin 4 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:1340173|PMID:10429671)
RGD PMID:10429671 PMID:21873635 MGI:1340173, RGD:13792537 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il7 interleukin 7 acts_upstream_of_or_within ISO (MGI:1340173|PMID:10429671) RGD PMID:10429671 MGI:1340173 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075
JBrowse link
G Itga6 integrin subunit alpha 6 involved_in ISO (PMID:21310825) RGD PMID:21310825 NCBI chr 3:56,604,512...56,689,428
Ensembl chr 3:56,617,268...56,689,428
JBrowse link
G Itgav integrin subunit alpha V involved_in ISO (PMID:10708943) RGD PMID:10708943 NCBI chr 3:68,838,524...68,926,653
Ensembl chr 3:68,838,189...68,926,639
JBrowse link
G Lgals3 galectin 3 involved_in ISO
IBA
(PMID:22761016)
PMID:21873635
RGD PMID:22761016 PMID:21873635 RGD:13792537 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
JBrowse link
G Lmna lamin A/C involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:4879057|PMID:21151901)
Ensembl
RGD
PMID:21151901 GO_REF:0000107 MGI:4879057 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
JBrowse link
G Nol3 nucleolar protein 3 involved_in ISO
IEA
IBA
(PMID:9560245)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:9560245 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Nrp1 neuropilin 1 involved_in ISO (MGI:5287519|PMID:21828096) RGD PMID:21828096 MGI:5287519 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
JBrowse link
G Pak5 p21 (RAC1) activated kinase 5 acts_upstream_of_or_within ISO (MGI:2673247|PMID:12897128) RGD PMID:12897128 MGI:2673247 NCBI chr 3:123,395,678...123,703,967
Ensembl chr 3:123,396,497...123,703,930
JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO
ISS
(PMID:21785459)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:21785459 GO_REF:0000024 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Peli3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO MGI:5441750 (MGI:5546581|PMID:23950925)
(PMID:24113711)
RGD PMID:23950925 PMID:24113711 MGI:5546581 NCBI chr 1:202,230,034...202,242,900
Ensembl chr 1:202,232,228...202,242,857
JBrowse link
G Phip pleckstrin homology domain interacting protein acts_upstream_of_or_within ISO (PMID:17636024) RGD PMID:17636024 NCBI chr 8:83,776,802...83,891,192
Ensembl chr 8:83,781,465...83,894,283
JBrowse link
G Prdx2 peroxiredoxin 2 acts_upstream_of_or_within ISO MGI:2668456 (MGI:3050700|PMID:15259009) RGD PMID:15259009 MGI:3050700 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
JBrowse link
G Psme3 proteasome activator subunit 3 involved_in ISO (PMID:18309296) RGD PMID:18309296 NCBI chr10:86,257,672...86,265,458
Ensembl chr10:86,257,668...86,333,804
JBrowse link
G Rb1cc1 RB1-inducible coiled-coil 1 acts_upstream_of_or_within ISO MGI:3690329 (MGI:3689241|PMID:17015619) RGD PMID:17015619 MGI:3689241 NCBI chr 5:13,161,648...13,225,560
Ensembl chr 5:13,161,648...13,225,560
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in
acts_upstream_of_or_within
ISO (PMID:21310825)
(MGI:5304595|PMID:22244329)
RGD PMID:21310825 PMID:22244329 MGI:5304595 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in
acts_upstream_of_or_within
ISO (PMID:21525013)
MGI:104798|MGI:109200 (MGI:5521568|PMID:22089168)
RGD PMID:21525013 PMID:22089168 MGI:5521568 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 acts_upstream_of_or_within ISO (MGI:4456959|PMID:11493700) RGD PMID:11493700 MGI:4456959 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Scg2 secretogranin II involved_in ISO (PMID:14970115) RGD PMID:14970115 NCBI chr 9:80,803,074...80,808,646
Ensembl chr 9:80,803,075...80,821,097
JBrowse link
G Sgms1 sphingomyelin synthase 1 acts_upstream_of_or_within ISO (MGI:3609513|PMID:16226406) RGD PMID:16226406 MGI:3609513 NCBI chr 1:229,996,673...230,259,591
Ensembl chr 1:229,998,119...230,259,603
JBrowse link
G Sh3rf1 SH3 domain containing ring finger 1 involved_in ISO (PMID:21586138) RGD PMID:21586138 NCBI chr16:28,735,522...28,901,690
Ensembl chr16:28,735,440...28,901,644
JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 involved_in ISO (PMID:21586138) RGD PMID:21586138 NCBI chr 2:142,913,924...142,931,752
Ensembl chr 2:142,914,003...142,931,950
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO
IBA
(PMID:19767770)
PMID:21873635
RGD PMID:19767770 PMID:21873635 RGD:13792537 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Tcf7l2 transcription factor 7 like 2 involved_in IMP PMID:21965303 BHF-UCL PMID:21965303 RGD:14974246 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO (PMID:18625725) RGD PMID:18625725 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 involved_in ISO (MGI:2150820|PMID:11567634) RGD PMID:11567634 MGI:2150820 NCBI chr 5:166,606,909...166,609,599
Ensembl chr 5:166,606,909...166,609,599
JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (MGI:5287519|PMID:21828096) RGD PMID:21828096 MGI:5287519 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Yap1 Yes1 associated transcriptional regulator acts_upstream_of_or_within ISO MGI:95484 (MGI:3818355|PMID:17980593) RGD PMID:17980593 MGI:3818355 NCBI chr 8:5,095,705...5,166,808
Ensembl chr 8:5,095,722...5,167,010
JBrowse link
G Zmynd11 zinc finger, MYND-type containing 11 involved_in ISO (PMID:20732415) RGD PMID:20732415 NCBI chr17:60,542,669...60,631,913
Ensembl chr17:60,543,077...60,631,902
JBrowse link
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 involved_in IMP PMID:18469807 UniProt PMID:18469807 RGD:8553892 NCBI chr 7:62,897,282...62,914,295
Ensembl chr 7:62,897,282...62,914,295
JBrowse link
G Bcl2 BCL2, apoptosis regulator acts_upstream_of_or_within ISO MGI:99702 (PMID:8358790) RGD PMID:8358790 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l10 Bcl2-like 10 acts_upstream_of_or_within ISO (MGI:1326939|PMID:9878060) RGD PMID:9878060 MGI:1326939 NCBI chr 8:76,107,326...76,113,373
Ensembl chr 8:76,107,326...76,113,367
JBrowse link
G Col2a1 collagen type II alpha 1 chain acts_upstream_of_or_within ISO MGI:2152978 (MGI:1097047|PMID:9299161) RGD PMID:9299161 MGI:1097047 NCBI chr 7:129,098,489...129,127,620
Ensembl chr 7:129,098,786...129,127,546
JBrowse link
G Csf2 colony stimulating factor 2 involved_in ISO (PMID:10666185) RGD PMID:10666185 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Ctnna1 catenin alpha 1 acts_upstream_of_or_within ISO MGI:2677796 (MGI:5315030|PMID:22411810) RGD PMID:22411810 MGI:5315030 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3777228|PMID:18322241), (MGI:3833195|PMID:18971423)
Ensembl
RGD
PMID:18322241 PMID:18971423 GO_REF:0000107 MGI:3777228 MGI:3833195 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 acts_upstream_of_or_within ISO MGI:2670351 (MGI:3833195|PMID:18971423) RGD PMID:18971423 MGI:3833195 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1857803 (MGI:3577160|PMID:15817220)
RGD PMID:15817220 PMID:21873635 MGI:3577160, RGD:13792537 NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483
JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:154,335,558...154,519,006
Ensembl chr 3:154,335,400...154,518,793
JBrowse link
G Eya3 EYA transcriptional coactivator and phosphatase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:144,806,523...144,934,522
Ensembl chr 5:144,806,577...144,934,518
JBrowse link
G Eya4 EYA transcriptional coactivator and phosphatase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:22,172,275...22,415,978
Ensembl chr 1:22,172,275...22,415,976
JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647 (MGI:3690587|PMID:16956603) RGD PMID:16956603 MGI:3690587 NCBI chr 2:50,801,897...50,875,428
Ensembl chr 2:50,800,992...50,876,866
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in IMP PMID:18469807 UniProt PMID:18469807 RGD:8553892 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
JBrowse link
G Gas1 growth arrest-specific 1 acts_upstream_of_or_within ISO (MGI:5306314|PMID:15070677) RGD PMID:15070677 MGI:5306314 NCBI chr17:4,482,014...4,485,155 JBrowse link
G Gata1 GATA binding protein 1 involved_in ISO (PMID:17167422) RGD PMID:17167422 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530
JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in ISO
IEA
(PMID:10921886)
GO_REF:0000107
RGD
Ensembl
PMID:10921886 GO_REF:0000107 NCBI chr 2:56,893,992...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Gfral GDNF family receptor alpha like acts_upstream_of_or_within ISO (MGI:3610244|PMID:16086688) RGD PMID:16086688 MGI:3610244 NCBI chr 8:76,917,894...76,963,349
Ensembl chr 8:76,918,657...76,959,425
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:17167422) RGD PMID:17167422
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:17167422) RGD PMID:17167422 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:10748004) RGD PMID:10748004 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il7 interleukin 7 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:84869|PMID:8950980)
Ensembl
RGD
PMID:8950980 GO_REF:0000107 MGI:84869 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075
JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 involved_in IMP PMID:20551324 BHF-UCL PMID:20551324 RGD:8553940 NCBI chr 8:63,625,220...63,852,090
Ensembl chr 8:63,625,221...63,851,983
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 involved_in ISO
IEA
UniProtKB:Q62862 (PMID:20551324)
GO_REF:0000107
RGD
Ensembl
PMID:20551324 GO_REF:0000107 NCBI chr10:46,170,264...46,176,262
Ensembl chr10:46,170,167...46,176,267
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in ISO (PMID:20921992) RGD PMID:20921992 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Nrg1 neuregulin 1 involved_in ISO (PMID:9553078) RGD PMID:9553078 NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Pf4 platelet factor 4 involved_in ISO (PMID:10666185) RGD PMID:10666185 NCBI chr14:17,298,438...17,299,148
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Prdx2 peroxiredoxin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:86755|PMID:9115640)
Ensembl
RGD
PMID:9115640 GO_REF:0000107 MGI:86755 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in ISO (MGI:5306563|PMID:20125124) RGD PMID:20125124 MGI:5306563 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Sgk3 serum/glucocorticoid regulated kinase family, member 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:2178763|PMID:11050396)
Ensembl
RGD
PMID:11050396 GO_REF:0000107 MGI:2178763 NCBI chr 5:9,345,761...9,472,243
Ensembl chr 5:9,346,040...9,415,476
JBrowse link
G Snai2 snail family transcriptional repressor 2 acts_upstream_of_or_within ISO (MGI:5142392|PMID:10518215) RGD PMID:10518215 MGI:5142392 NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Stradb STE20 related adaptor beta acts_upstream_of_or_within ISO (MGI:2656105|PMID:12574163) RGD PMID:12574163 MGI:2656105 NCBI chr 9:60,414,182...60,433,084
Ensembl chr 9:60,414,182...60,433,084
JBrowse link
G Tert telomerase reverse transcriptase involved_in ISO (PMID:10449030) RGD PMID:10449030 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:10666185), (PMID:10748004) RGD PMID:10666185 PMID:10748004 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Unc5b unc-5 netrin receptor B involved_in ISO
IEA
(PMID:18469807)
GO_REF:0000107
RGD
Ensembl
PMID:18469807 GO_REF:0000107 NCBI chr20:28,697,726...28,764,474
Ensembl chr20:28,697,726...28,764,537
JBrowse link
G Zc3hc1 zinc finger, C3HC-type containing 1 acts_upstream_of_or_within ISO (MGI:2670822|PMID:12748172) RGD PMID:12748172 MGI:2670822 NCBI chr 4:58,989,989...59,011,925
Ensembl chr 4:58,989,987...59,011,933
JBrowse link
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:22711822) RGD PMID:22711822 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355
JBrowse link
G Bcl2l1 Bcl2-like 1 acts_upstream_of_or_within ISO (PMID:26582200) RGD PMID:26582200 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Brca1 BRCA1, DNA repair associated involved_in ISO
IEA
(PMID:23415688)
GO_REF:0000107
RGD
Ensembl
PMID:23415688 GO_REF:0000107 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Caps calcyphosine acts_upstream_of_or_within ISO (MGI:2450205|PMID:12466268) RGD PMID:12466268 MGI:2450205 NCBI chr 9:1,544,597...1,545,631
Ensembl chr 9:1,544,719...1,545,647
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:26582200)
(PMID:18202225)
RGD PMID:18202225 PMID:26582200 PMID:21873635 RGD:13792537 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Dapk1 death associated protein kinase 1 acts_upstream_of_or_within ISO (MGI:2152512|PMID:11485996) RGD PMID:11485996 MGI:2152512 NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:18846110) RGD PMID:18846110 NCBI chr  X:9,479,532...9,493,455
Ensembl chr  X:9,479,532...9,493,168
JBrowse link
G Faim Fas apoptotic inhibitory molecule involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:1332875|PMID:10075978)
RGD PMID:10075978 PMID:21873635 MGI:1332875, RGD:13792537 NCBI chr 8:99,543,877...99,569,499
Ensembl chr 8:99,542,405...99,560,562
JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:26582200)
GO_REF:0000107
RGD
Ensembl
PMID:26582200 GO_REF:0000107 NCBI chr 7:130,632,368...130,659,353
Ensembl chr 7:130,633,348...130,659,168
JBrowse link
G Fga fibrinogen alpha chain involved_in IBA
ISO
PMID:21873635
(PMID:10903502)
RGD PMID:10903502 PMID:21873635 RGD:13792537 NCBI chr 2:168,365,364...168,381,533
Ensembl chr 2:168,374,120...168,381,528
JBrowse link
G Fgb fibrinogen beta chain involved_in ISO (PMID:10903502) RGD PMID:10903502 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
JBrowse link
G Fgg fibrinogen gamma chain involved_in ISO (PMID:10903502) RGD PMID:10903502 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:12221075)
Ensembl
RGD
PMID:12221075 GO_REF:0000107 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:18846110)
UniProt
Ensembl
RGD
PMID:18846110 GO_REF:0000024 GO_REF:0000107 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Hgf hepatocyte growth factor acts_upstream_of_or_within ISO (MGI:3054501|PMID:15314156) RGD PMID:15314156 MGI:3054501 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Hmgb2 high mobility group box 2 acts_upstream_of_or_within ISO MGI:2387671 (MGI:3831045|PMID:19139395) RGD PMID:19139395 MGI:3831045 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
JBrowse link
G Hmox1 heme oxygenase 1 involved_in ISO (PMID:18202225) RGD PMID:18202225 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Icam1 intercellular adhesion molecule 1 involved_in ISO (PMID:10903502) RGD PMID:10903502 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Itprip inositol 1,4,5-trisphosphate receptor interacting protein acts_upstream_of_or_within ISO MGI:1916885 (MGI:4431305|PMID:20053891) RGD PMID:20053891 MGI:4431305 NCBI chr 1:246,762,804...246,786,364
Ensembl chr 1:246,762,472...246,786,408
JBrowse link
G LOC684466 similar to Fas apoptotic inhibitory molecule 1 (rFAIM) involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:99,791,849...99,810,206
Ensembl chr 8:99,791,981...99,810,228
JBrowse link
G Nol3 nucleolar protein 3 involved_in IMP PMID:12191471
PMID:15383280
UniProt PMID:12191471 PMID:15383280 RGD:631884, RGD:10047289 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Pea15 proliferation and apoptosis adaptor protein 15 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:10442631)
(MGI:3687663|PMID:10588860)
PMID:21873635
RGD PMID:10442631 PMID:10588860 PMID:21873635 MGI:3687663, RGD:13792537 NCBI chr13:84,657,815...84,667,437
Ensembl chr13:84,654,870...84,667,499
JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO (MGI:1099227|PMID:9353287) RGD PMID:9353287 MGI:1099227 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO MGI:2388026|MGI:95484|MGI:99255 (MGI:3612236|PMID:16365167) RGD PMID:16365167 MGI:3612236 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase involved_in IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:15069192)
UniProt
RGD
PMID:15069192 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr10:67,740,711...67,803,694
Ensembl chr10:67,740,712...67,824,434
JBrowse link
G Rnf34 ring finger protein 34 involved_in IBA
ISO
ISS
PMID:21873635
(PMID:15069192)
GO_REF:0000024
RGD
UniProt
PMID:15069192 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr12:33,703,655...33,724,606
Ensembl chr12:33,703,673...33,724,586
JBrowse link
G Serpine1 serpin family E member 1 involved_in ISO
IEA
(PMID:18835034)
GO_REF:0000107
RGD
Ensembl
PMID:18835034 GO_REF:0000107 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 involved_in ISO (MGI:4835156|PMID:9391078) RGD PMID:9391078 MGI:4835156 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
JBrowse link
G Tmbim1 transmembrane BAX inhibitor motif containing 1 involved_in ISO
ISS
(PMID:21107705)
GO_REF:0000024
RGD
UniProt
PMID:21107705 GO_REF:0000024 NCBI chr 9:75,871,835...75,889,366
Ensembl chr 9:75,871,835...75,889,069
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (PMID:12167698) RGD PMID:12167698 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in ISO UniProtKB:Q99LX0 (PMID:14652021)
(MGI:5613479|PMID:14652021)
RGD PMID:14652021 MGI:5613479 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:21177249), (PMID:23261939) RGD PMID:21177249 PMID:23261939 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eno1 enolase 1 involved_in ISO UniProtKB:Q01986 (PMID:15459207) RGD PMID:15459207 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Hyou1 hypoxia up-regulated 1 involved_in IBA
ISO
IDA
PMID:21873635
(PMID:10037731)
PMID:11231630
RGD PMID:10037731 PMID:21873635 PMID:11231630 RGD:13792537, RGD:10047348 NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186
JBrowse link
G Kdm6a lysine demethylase 6A IMP RGD PMID:30887465 RGD:151665136 NCBI chr  X:4,337,466...4,477,100
Ensembl chr  X:4,337,750...4,477,062
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 involved_in IGI
IMP
PMID:15459207 CAFA PMID:15459207 PMID:15459207 RGD:12793039, RGD:12793039 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Nol3 nucleolar protein 3 involved_in IDA PMID:10590251 UniProt PMID:10590251 RGD:10047155 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta involved_in IEA
ISO
GO_REF:0000107
(MGI:6444553|PMID:30496354)
Ensembl
RGD
PMID:30496354 GO_REF:0000107 MGI:6444553 NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (MGI:5558956|PMID:24553947) RGD PMID:24553947 MGI:5558956 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO (PMID:21075086) RGD PMID:21075086 NCBI chr 7:130,512,428...130,543,637
Ensembl chr 7:130,527,316...130,543,633
JBrowse link
negative regulation of intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC098008.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 1:157,043,792...157,044,304 JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (MGI:4999711|PMID:19911006) RGD PMID:19911006 MGI:4999711 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in ISO
IBA
(PMID:11684014)
PMID:21873635
RGD PMID:11684014 PMID:21873635 RGD:13792537 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in IBA
ISO
PMID:21873635
(PMID:21567405)
(PMID:12011449)
RGD PMID:12011449 PMID:21567405 PMID:21873635 RGD:13792537 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l10 Bcl2-like 10 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:1326939|PMID:9878060)
RGD PMID:9878060 PMID:21873635 MGI:1326939, RGD:13792537 NCBI chr 8:76,107,326...76,113,373
Ensembl chr 8:76,107,326...76,113,367
JBrowse link
G Bcl2l2 Bcl2-like 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:21883093) RGD PMID:21883093 NCBI chr  X:9,479,532...9,493,455
Ensembl chr  X:9,479,532...9,493,168
JBrowse link
G Fignl1 fidgetin-like 1 acts_upstream_of_or_within ISO (MGI:4944122|PMID:20886204) RGD PMID:20886204 MGI:4944122 NCBI chr14:86,368,670...86,381,728
Ensembl chr14:86,368,675...86,377,455
JBrowse link
G G2e3 G2/M-phase specific E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:3808723 (MGI:3807157|PMID:18511420) RGD PMID:18511420 MGI:3807157 NCBI chr 6:68,763,847...68,795,305
Ensembl chr 6:68,764,185...68,793,924
JBrowse link
G Gcg glucagon involved_in ISO (MGI:4453294|PMID:19915011) RGD PMID:19915011 MGI:4453294 NCBI chr 3:47,113,914...47,122,929
Ensembl chr 3:47,113,914...47,122,929
JBrowse link
G Hdac1 histone deacetylase 1 acts_upstream_of_or_within ISO MGI:1097691 (MGI:4889029|PMID:21093383) RGD PMID:21093383 MGI:4889029 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
JBrowse link
G Hdac2 histone deacetylase 2 acts_upstream_of_or_within ISO MGI:108086 (MGI:4889029|PMID:21093383) RGD PMID:21093383 MGI:4889029 NCBI chr20:40,548,250...40,571,609
Ensembl chr20:40,548,250...40,571,609
JBrowse link
G Hells helicase, lymphoid specific acts_upstream_of_or_within ISO MGI:2178586 (MGI:2178571|PMID:11325543) RGD PMID:11325543 MGI:2178571 NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in ISO UniProtKB:P37840 (PMID:22045699) RGD PMID:22045699 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
JBrowse link
G Ivns1abp influenza virus NS1A binding protein acts_upstream_of_or_within ISO MGI:4820513 (MGI:4819697|PMID:15485691) RGD PMID:15485691 MGI:4819697 NCBI chr13:63,427,040...63,446,701
Ensembl chr13:63,427,041...63,446,701
JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 acts_upstream_of_or_within ISO (MGI:1332866|PMID:10098834) RGD PMID:10098834 MGI:1332866 NCBI chr 3:78,355,051...78,372,946
Ensembl chr 3:78,355,048...78,372,884
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mmp9 matrix metallopeptidase 9 involved_in IEA
ISO
GO_REF:0000107
(PMID:22984561)
Ensembl
RGD
PMID:22984561 GO_REF:0000107 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 involved_in ISO (PMID:16826196) RGD PMID:16826196 NCBI chr16:19,526,633...19,533,567
Ensembl chr16:19,526,565...19,535,726
JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 involved_in ISO (PMID:16826196) RGD PMID:16826196 NCBI chr 3:76,876,646...76,883,824
Ensembl chr 3:76,876,646...76,883,824
JBrowse link
G Noc2l NOC2-like nucleolar associated transcriptional repressor involved_in ISO (PMID:16322561) RGD PMID:16322561 NCBI chr 5:166,820,075...166,831,951
Ensembl chr 5:166,820,161...166,831,949
JBrowse link
G Nol3 nucleolar protein 3 involved_in IMP
IBA
PMID:15383280
PMID:21873635
UniProt
GO_Central
PMID:15383280 PMID:21873635 RGD:10047289, RGD:13792537 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISO (MGI:3692706|PMID:16839884) RGD PMID:16839884 MGI:3692706 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G Parl presenilin associated, rhomboid-like involved_in ISS
ISO
GO_REF:0000024
(MGI:3692706|PMID:16839884)
ParkinsonsUK-UCL
RGD
PMID:16839884 GO_REF:0000024 MGI:3692706 NCBI chr11:80,594,059...80,620,506
Ensembl chr11:80,593,192...80,620,506
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:15087508) RGD PMID:15087508 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Plaur plasminogen activator, urokinase receptor involved_in ISO (PMID:22984561) RGD PMID:22984561 NCBI chr 1:80,053,441...80,068,384
Ensembl chr 1:80,050,324...80,068,595
JBrowse link
G Ppif peptidylprolyl isomerase F involved_in ISO
ISS
(PMID:19228691)
GO_REF:0000024
RGD
UniProt
PMID:19228691 GO_REF:0000024 NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913
JBrowse link
G Rtkn2 rhotekin 2 involved_in ISO (PMID:26124677) RGD PMID:26124677 NCBI chr20:20,525,256...20,609,951
Ensembl chr20:20,525,256...20,609,951
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in IBA
ISO
PMID:21873635
(PMID:19767770)
RGD PMID:19767770 PMID:21873635 RGD:13792537 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Uri1 URI1, prefoldin-like chaperone involved_in ISO (PMID:17936702) RGD PMID:17936702 NCBI chr 1:90,646,392...90,704,811
Ensembl chr 1:90,646,393...90,709,026
JBrowse link
G Vdac2 voltage-dependent anion channel 2 involved_in ISO (MGI:5315363|PMID:12881569) RGD PMID:12881569 MGI:5315363 NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553
JBrowse link
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Armc10 armadillo repeat containing 10 involved_in IBA
ISO
PMID:21873635
(PMID:17904127)
RGD PMID:17904127 PMID:21873635 RGD:13792537 NCBI chr 4:13,399,004...13,414,594
Ensembl chr 4:13,395,207...13,414,548
JBrowse link
G Cep63 centrosomal protein 63 acts_upstream_of_or_within ISO MGI:98834 (MGI:5662131|PMID:26158450) RGD PMID:26158450 MGI:5662131 NCBI chr 8:103,162,639...103,214,177
Ensembl chr 8:103,162,700...103,214,177
JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in ISO (PMID:17310983) RGD PMID:17310983 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mdm4 MDM4 regulator of p53 involved_in ISO (MGI:2182884|PMID:12101245) RGD PMID:12101245 MGI:2182884 NCBI chr13:44,432,596...44,516,165
Ensembl chr13:44,406,213...44,474,226
JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:18829576) RGD PMID:18829576 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:23985028) RGD PMID:23985028 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Pttg1ip PTTG1 interacting protein acts_upstream_of_or_within ISO (PMID:24506068) RGD PMID:24506068 NCBI chr20:11,030,013...11,047,742
Ensembl chr20:11,030,015...11,047,316
JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B acts_upstream_of_or_within ISO MGI:2672883 (MGI:2670318|PMID:12858174) RGD PMID:12858174 MGI:2670318 NCBI chr 7:69,077,024...69,108,742
Ensembl chr 7:69,078,291...69,108,633
JBrowse link
G Rrn3 RRN3 homolog, RNA polymerase I transcription factor acts_upstream_of_or_within ISO MGI:3584037 (MGI:3583493|PMID:15989966) RGD PMID:15989966 MGI:3583493 NCBI chr10:2,129,949...2,165,381
Ensembl chr10:2,129,978...2,165,663
JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 involved_in ISO (MGI:5553386|PMID:24523556) RGD PMID:24523556 MGI:5553386 NCBI chr 2:233,750,838...233,784,817
Ensembl chr 2:233,750,838...233,784,784
JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ackr3 atypical chemokine receptor 3 involved_in ISO (PMID:20388803) RGD PMID:20388803 NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237
JBrowse link
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of_or_within ISO (MGI:3584078|PMID:15983387) RGD PMID:15983387 MGI:3584078 NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845
JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in ISO (PMID:16608847) RGD PMID:16608847 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bid BH3 interacting domain death agonist acts_upstream_of_or_within ISO MGI:5428930 (MGI:5662300|PMID:26219591) RGD PMID:26219591 MGI:5662300 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Ccar2 cell cycle and apoptosis regulator 2 involved_in ISO (PMID:23352644) RGD PMID:23352644 NCBI chr15:45,212,797...45,228,001
Ensembl chr15:45,212,803...45,227,636
JBrowse link
G Cdkn2d cyclin dependent kinase inhibitor 2D involved_in ISO (PMID:15750620) RGD PMID:15750620 NCBI chr 8:19,831,874...19,834,640
Ensembl chr 8:19,831,866...19,834,674
JBrowse link
G Clu clusterin involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:16113678)
UniProt
Ensembl
RGD
PMID:16113678 GO_REF:0000024 GO_REF:0000107 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 involved_in ISO (PMID:20388803) RGD PMID:20388803 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Ddias DNA damage-induced apoptosis suppressor involved_in ISO (PMID:24214091) RGD PMID:24214091 NCBI chr 1:146,906,150...146,930,462
Ensembl chr 1:146,906,154...146,930,462
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 involved_in ISO (PMID:14561758) RGD PMID:14561758 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
JBrowse link
G Snai1 snail family transcriptional repressor 1 involved_in ISO (PMID:15314165) RGD PMID:15314165 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in ISO (PMID:15314165) RGD PMID:15314165 NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Tmem161a transmembrane protein 161A involved_in ISO (PMID:16551573) RGD PMID:16551573 NCBI chr16:19,237,638...19,248,151
Ensembl chr16:19,238,487...19,248,087
JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 acts_upstream_of_or_within ISO (PMID:11598139) RGD PMID:11598139 NCBI chr15:51,156,728...51,159,629
Ensembl chr15:51,146,154...51,159,625
JBrowse link
G Trim32 tripartite motif-containing 32 involved_in ISO (PMID:18632609) RGD PMID:18632609 NCBI chr 5:79,005,139...79,016,615
Ensembl chr 5:78,999,389...79,022,018
JBrowse link
G Usp47 ubiquitin specific peptidase 47 acts_upstream_of_or_within ISO MGI:4130032 (MGI:4839431|PMID:19966869) RGD PMID:19966869 MGI:4839431 NCBI chr 1:166,152,104...166,235,312
Ensembl chr 1:166,152,199...166,235,312
JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family, AAA domain containing 5 involved_in ISO (MGI:3584078|PMID:15983387) RGD PMID:15983387 MGI:3584078 NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845
JBrowse link
G Bcl2l12 Bcl2 like 12 acts_upstream_of_or_within ISO (MGI:4834958|PMID:20837658) RGD PMID:20837658 MGI:4834958 NCBI chr 1:95,472,272...95,480,991
Ensembl chr 1:95,472,272...95,480,991
JBrowse link
G Cd44 CD44 molecule (Indian blood group) involved_in ISO (PMID:17045821)
(MGI:3690285|PMID:17045821)
RGD PMID:17045821 MGI:3690285 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd74 CD74 molecule involved_in ISO
ISS
IBA
(PMID:17045821)
GO_REF:0000024
(MGI:3690285|PMID:17045821)
PMID:21873635
RGD
BHF-UCL
PMID:17045821 PMID:21873635 GO_REF:0000024 MGI:3690285, RGD:13792537 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Ell3 elongation factor for RNA polymerase II 3 acts_upstream_of_or_within ISO (MGI:5438719|PMID:22768269) RGD PMID:22768269 MGI:5438719 NCBI chr 3:108,413,035...108,417,181
Ensembl chr 3:108,410,448...108,417,132
JBrowse link
G Kdm1a lysine demethylase 1A involved_in ISO (PMID:17805299) RGD PMID:17805299 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319
JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 involved_in ISS
ISO
GO_REF:0000024
(PMID:29295817)
UniProt
RGD
PMID:29295817 GO_REF:0000024 NCBI chr 3:44,680,229...44,720,172
Ensembl chr 3:44,681,632...44,720,168
JBrowse link
G Mif macrophage migration inhibitory factor involved_in ISO (PMID:17045821) RGD PMID:17045821 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Muc1 mucin 1, cell surface associated involved_in ISO (PMID:15710329) RGD PMID:15710329 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (MGI:2152474|PMID:11672522) RGD PMID:11672522 MGI:2152474 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 involved_in ISO (PMID:15735003) RGD PMID:15735003 NCBI chr12:41,267,534...41,270,053
Ensembl chr12:41,267,549...41,270,042
JBrowse link
G Zfp385a zinc finger protein 385A involved_in ISO (PMID:17719541) RGD PMID:17719541 NCBI chr 7:134,448,914...134,475,548
Ensembl chr 7:134,448,921...134,475,548
JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsph1 heat shock protein family H (Hsp110) member 1 acts_upstream_of_or_within ISO (MGI:3822965|PMID:18681888) RGD PMID:18681888 MGI:3822965 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO
IMP
(PMID:17579517) RGD PMID:17579517 PMID:17579517 RGD:8693356 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Trap1 TNF receptor-associated protein 1 involved_in IMP PMID:17579517 ParkinsonsUK-UCL PMID:17579517 RGD:8693356 NCBI chr10:11,464,882...11,498,931
Ensembl chr10:11,464,821...11,498,981
JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:22711822) RGD PMID:22711822 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355
JBrowse link
G Bdkrb2 bradykinin receptor B2 acts_upstream_of_or_within ISO MGI:1857135 (MGI:3654719|PMID:16571598) RGD PMID:16571598 MGI:3654719 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497
JBrowse link
G Epo erythropoietin involved_in ISO (PMID:14569084) RGD PMID:14569084 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G Ptger2 prostaglandin E receptor 2 involved_in ISO (PMID:21716255) RGD PMID:21716255 NCBI chr15:18,215,013...18,228,714
Ensembl chr15:18,217,285...18,228,714
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 involved_in ISO (PMID:21716255)
(MGI:5474549|PMID:21716255)
RGD PMID:21716255 MGI:5474549 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ybx3 Y box binding protein 3 involved_in IEA
ISO
GO_REF:0000107
(PMID:22711822)
Ensembl
RGD
PMID:22711822 GO_REF:0000107 NCBI chr 4:165,129,747...165,153,101
Ensembl chr 4:165,129,758...165,153,161
JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb2 bradykinin receptor B2 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:98834|MGI:99702 (MGI:3654719|PMID:16571598)
GO_REF:0000107
RGD
Ensembl
PMID:16571598 GO_REF:0000107 MGI:3654719 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497
JBrowse link
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa2 acetyl-CoA acyltransferase 2 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:18371312)
Ensembl
UniProt
RGD
PMID:18371312 GO_REF:0000024 GO_REF:0000107 NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249
JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in ISO (PMID:15901672) RGD PMID:15901672 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in ISO (PMID:9393856)
(PMID:15901672), (PMID:9393856)
RGD PMID:9393856 PMID:15901672 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISO (MGI:5796062|PMID:27098698) RGD PMID:27098698 MGI:5796062 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within ISO MGI:104995 (MGI:3047441|PMID:15288121) RGD PMID:15288121 MGI:3047441 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:20625543) RGD PMID:20625543
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:20625543) RGD PMID:20625543 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within ISO (MGI:4437986|PMID:19096392) RGD PMID:19096392 MGI:4437986 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Mpv17l MPV17 mitochondrial inner membrane protein like involved_in ISO (PMID:22306510) RGD PMID:22306510 NCBI chr10:1,988,451...2,025,300
Ensembl chr10:1,988,136...2,007,649
JBrowse link
G Slc25a31 solute carrier family 25 member 31 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:123,695,387...123,711,275
Ensembl chr 2:123,695,408...123,710,795
JBrowse link
G Slc25a4 solute carrier family 25 member 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733
JBrowse link
G Slc25a5 solute carrier family 25 member 5 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:19154410)
UniProt
RGD
PMID:19154410 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr  X:116,031,896...116,034,963
Ensembl chr  X:116,031,803...116,034,967
JBrowse link
G Slc35f6 solute carrier family 35, member F6 involved_in ISS
ISO
GO_REF:0000024
(PMID:19154410)
UniProt
RGD
PMID:19154410 GO_REF:0000024 NCBI chr 6:25,725,822...25,737,720
Ensembl chr 6:25,725,819...25,737,730
JBrowse link
G Tmem14a transmembrane protein 14A involved_in ISO (PMID:21723035) RGD PMID:21723035 NCBI chr 9:23,640,594...23,652,379
Ensembl chr 9:23,733,039...23,734,463
Ensembl chr 9:23,733,039...23,734,463
JBrowse link
negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 involved_in ISO (PMID:14752510) RGD PMID:14752510 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967
JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:14752510) RGD PMID:14752510 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag5 BAG cochaperone 5 involved_in ISO (PMID:24475098) RGD PMID:24475098 NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970
JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2158814 (MGI:3698597|PMID:16373599)
Ensembl
RGD
PMID:16373599 GO_REF:0000107 MGI:3698597 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:3581090|PMID:15731106)
Ensembl
RGD
PMID:15731106 GO_REF:0000107 MGI:3581090 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 involved_in ISO
IEA
(PMID:23043106)
GO_REF:0000107
RGD
Ensembl
PMID:23043106 GO_REF:0000107 NCBI chr10:46,170,264...46,176,262
Ensembl chr10:46,170,167...46,176,267
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 involved_in ISO (PMID:23043106) RGD PMID:23043106 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nme5 NME/NM23 family member 5 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:2664629|PMID:12788088)
RGD PMID:12788088 PMID:21873635 MGI:2664629, RGD:13792537 NCBI chr18:26,163,558...26,180,742
Ensembl chr18:26,163,555...26,180,794
JBrowse link
G Nol3 nucleolar protein 3 involved_in ISO
IEA
(PMID:15004034)
GO_REF:0000107
RGD
Ensembl
PMID:15004034 GO_REF:0000107 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Ppia peptidylprolyl isomerase A involved_in ISO
ISS
(PMID:26095851)
GO_REF:0000024
RGD
UniProt
PMID:26095851 GO_REF:0000024 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr14:21,006,522...21,007,284
Ensembl chr14:21,006,538...21,007,310
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:17317627) RGD PMID:17317627 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Sod2 superoxide dismutase 2 involved_in ISO (PMID:12551919) RGD PMID:12551919 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Vnn1 vanin 1 involved_in ISO (MGI:3052282|PMID:15282320) RGD PMID:15282320 MGI:3052282 NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
JBrowse link
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in ISO
IEA
(PMID:24899725)
GO_REF:0000107
RGD
Ensembl
PMID:24899725 GO_REF:0000107 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Nono non-POU domain containing, octamer-binding involved_in ISO (PMID:15790595) RGD PMID:15790595 NCBI chr  X:66,554,131...66,571,992
Ensembl chr  X:66,554,098...66,571,952
JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO
ISS
(PMID:15790595)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:15790595 GO_REF:0000024 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
ISS
(PMID:17314283)
(MGI:5543313|PMID:23858059)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:17314283 PMID:23858059 GO_REF:0000024 MGI:5543313 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
negative regulation of release of cytochrome c from mitochondria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5294538|PMID:18977203)
UniProt
RGD
PMID:18977203 GO_REF:0000024 MGI:5294538 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Arrb2 arrestin, beta 2 IMP RGD PMID:19171933 RGD:5510006 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Avp arginine vasopressin involved_in ISO (PMID:18402937) RGD PMID:18402937 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in ISO (PMID:15901672) RGD PMID:15901672 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in ISO (PMID:9393856)
(PMID:15901672), (PMID:9393856)
RGD PMID:9393856 PMID:15901672 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l2 Bcl2-like 2 IDA RGD PMID:10724126 RGD:14394498 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624
JBrowse link
G Fxn frataxin involved_in IEA
ISO
GO_REF:0000107
(PMID:16608849)
Ensembl
RGD
PMID:16608849 GO_REF:0000107 NCBI chr 1:221,874,007...221,897,841
Ensembl chr 1:221,872,420...221,897,540
JBrowse link
G Ghitm growth hormone inducible transmembrane protein involved_in ISO (PMID:18417609) RGD PMID:18417609 NCBI chr16:12,885,551...12,897,887
Ensembl chr16:12,885,553...12,897,879
JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in ISO
IEA
(PMID:12221075)
GO_REF:0000107
RGD
Ensembl
PMID:12221075 GO_REF:0000107 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Hgf hepatocyte growth factor involved_in ISO (PMID:20655899) RGD PMID:20655899 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A acts_upstream_of_or_within ISO (MGI:5306879|PMID:21856340) RGD PMID:21856340 MGI:5306879 NCBI chr 8:121,514,152...121,523,382
Ensembl chr 8:121,514,156...121,523,443
JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5294538|PMID:18977203)
UniProt
RGD
PMID:18977203 GO_REF:0000024 MGI:5294538 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Lmna lamin A/C involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:4879057|PMID:21151901)
Ensembl
RGD
PMID:21151901 GO_REF:0000107 MGI:4879057 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
JBrowse link
G Mfn2 mitofusin 2 IMP RGD PMID:18006463 RGD:12738362 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Nol3 nucleolar protein 3 involved_in IDA
IEA
IBA
ISO
PMID:10590251
GO_REF:0000107
PMID:21873635
(PMID:15004034)
Ensembl
RGD
PMID:15004034 PMID:10590251 PMID:21873635 GO_REF:0000107, RGD:10047155, RGD:13792537 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISS
ISO
GO_REF:0000024
(MGI:3692706|PMID:16839884)
(PMID:21149567)
ParkinsonsUK-UCL
RGD
PMID:16839884 PMID:21149567 GO_REF:0000024 MGI:3692706 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G Pam16 presequence translocase associated motor 16 IDA RGD PMID:24069394 RGD:13462066 NCBI chr10:10,942,534...10,950,654
Ensembl chr10:10,943,001...10,950,649
JBrowse link
G Parl presenilin associated, rhomboid-like involved_in ISS
ISO
GO_REF:0000024
(MGI:3692706|PMID:16839884)
ParkinsonsUK-UCL
RGD
PMID:16839884 GO_REF:0000024 MGI:3692706 NCBI chr11:80,594,059...80,620,506
Ensembl chr11:80,593,192...80,620,506
JBrowse link
G Ppif peptidylprolyl isomerase F involved_in ISS
ISO
GO_REF:0000024
(PMID:19228691)
UniProt
RGD
PMID:19228691 GO_REF:0000024 NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913
JBrowse link
G Prelid1 PRELI domain containing 1 involved_in ISO (PMID:23931759) RGD PMID:23931759 NCBI chr17:9,305,349...9,308,389
Ensembl chr17:9,305,361...9,308,407
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
ISS
(PMID:19880420), (PMID:23453807)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:19880420 PMID:23453807 GO_REF:0000024 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 involved_in ISO
ISS
(PMID:19729910)
GO_REF:0000024
RGD
UniProt
PMID:19729910 GO_REF:0000024 NCBI chr  X:104,656,809...104,665,126
Ensembl chr  X:104,656,812...104,665,097
JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 involved_in ISO (PMID:23931759) RGD PMID:23931759 NCBI chr12:41,267,534...41,270,053
Ensembl chr12:41,267,549...41,270,042
JBrowse link
negative regulation of TRAIL-activated apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir221 microRNA 221 involved_in ISO (PMID:18246122), (PMID:19962668) RGD PMID:18246122 PMID:19962668 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573
JBrowse link
G Mir222 microRNA 222 involved_in ISO (PMID:18246122), (PMID:19962668) RGD PMID:18246122 PMID:19962668 NCBI chr  X:3,428,904...3,429,006
Ensembl chr  X:3,428,904...3,429,006
JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISS
ISO
GO_REF:0000024
(PMID:21785459)
ParkinsonsUK-UCL
RGD
PMID:21785459 GO_REF:0000024 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
positive regulation of apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07025928.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 4:51,682,224...51,682,961 JBrowse link
G AABR07052430.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Adora2a adenosine A2a receptor acts_upstream_of_or_within ISO MGI:2155985 (MGI:1860411|PMID:10845921) RGD PMID:10845921 MGI:1860411 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 acts_upstream_of_or_within ISO MGI:1889507 (MGI:3603971|PMID:16183742) RGD PMID:16183742 MGI:3603971 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Bid BH3 interacting domain death agonist acts_upstream_of_or_within ISO (MGI:84156|PMID:8918887) RGD PMID:8918887 MGI:84156 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bmf Bcl2 modifying factor acts_upstream_of_or_within ISO (MGI:2158578|PMID:11546872) RGD PMID:11546872 MGI:2158578 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta acts_upstream_of_or_within ISO (MGI:3710042|PMID:17367784) RGD PMID:17367784 MGI:3710042 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
JBrowse link
G Casp2 caspase 2 acts_upstream_of_or_within ISO MGI:1889507 (MGI:3603971|PMID:16183742) RGD PMID:16183742 MGI:3603971 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1889507 (MGI:3603971|PMID:16183742)
RGD PMID:16183742 PMID:21873635 MGI:3603971, RGD:13792537 NCBI chr 7:29,940,240...29,952,907
Ensembl chr 7:29,798,586...29,952,907
JBrowse link
G Ctsc cathepsin C acts_upstream_of_or_within ISO MGI:107285 (MGI:4838939|PMID:20435891) RGD PMID:20435891 MGI:4838939 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
JBrowse link
G Ctsh cathepsin H acts_upstream_of_or_within ISO MGI:109553 (MGI:4838939|PMID:20435891) RGD PMID:20435891 MGI:4838939 NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824
JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
ISO
GO_REF:0000024
(PMID:19903888)
UniProt
RGD
PMID:19903888 GO_REF:0000024 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280
JBrowse link
G Daxx death-domain associated protein acts_upstream_of_or_within ISO MGI:104662 (MGI:4942266|PMID:10684855) RGD PMID:10684855 MGI:4942266 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
JBrowse link
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 acts_upstream_of_or_within ISO MGI:3574590 (MGI:3573962|PMID:15680327) RGD PMID:15680327 MGI:3573962 NCBI chr17:26,148,652...26,159,358
Ensembl chr17:26,148,633...26,215,720
JBrowse link
G Fas Fas cell surface death receptor involved_in ISO (PMID:11096076) RGD PMID:11096076 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Ifnb1 interferon beta 1 involved_in ISO (PMID:10918594), (PMID:11337497) RGD PMID:10918594 PMID:11337497 NCBI chr 5:103,020,969...103,021,523
Ensembl chr 5:103,020,969...103,021,523
JBrowse link
G Il19 interleukin 19 acts_upstream_of_or_within ISO (MGI:2653146|PMID:12370360) RGD PMID:12370360 MGI:2653146 NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473
JBrowse link
G Inca1 inhibitor of CDK, cyclin A1 interacting protein 1 acts_upstream_of_or_within ISO UniProtKB:Q8WYH8 (MGI:5287344|PMID:21750715) RGD PMID:21750715 MGI:5287344 NCBI chr10:55,401,982...55,414,364
Ensembl chr10:55,401,982...55,414,114
JBrowse link
G Ing5 inhibitor of growth family, member 5 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2144284 (MGI:5287344|PMID:21750715)
RGD PMID:21750715 PMID:21873635 MGI:5287344, RGD:13792537 NCBI chr 9:94,326,919...94,344,220
Ensembl chr 9:94,326,548...94,344,220
JBrowse link
G Inhbb inhibin subunit beta B involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:98957 (MGI:4454604|PMID:20454446)
Ensembl
RGD
PMID:20454446 GO_REF:0000107 MGI:4454604 NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832
JBrowse link
G Jak2 Janus kinase 2 acts_upstream_of_or_within ISO (MGI:3036919|PMID:15012602) RGD PMID:15012602 MGI:3036919 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Maged1 MAGE family member D1 acts_upstream_of_or_within ISO MGI:1929608 (MGI:3848096|PMID:19268530), (MGI:4359364|PMID:17488777) RGD PMID:17488777 PMID:19268530 MGI:3848096 MGI:4359364 NCBI chr  X:59,422,715...59,429,381
Ensembl chr  X:59,422,717...59,429,364
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 acts_upstream_of_or_within ISO MGI:1346862 (MGI:3619752|PMID:16458303) RGD PMID:16458303 MGI:3619752 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 acts_upstream_of_or_within ISO MGI:1346861 (MGI:3619752|PMID:16458303) RGD PMID:16458303 MGI:3619752 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mir449a microRNA 449a involved_in ISO (PMID:25487955) RGD PMID:25487955 NCBI chr 2:44,670,714...44,670,804
Ensembl chr 2:44,670,714...44,670,804
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor acts_upstream_of_or_within ISO MGI:2447604 (MGI:2677658|PMID:14517295) RGD PMID:14517295 MGI:2677658 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 acts_upstream_of_or_within ISO (MGI:4829576|PMID:20530871) RGD PMID:20530871 MGI:4829576 NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610
JBrowse link
G Ngfr nerve growth factor receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:1859527|PMID:10764727)
Ensembl
RGD
PMID:10764727 GO_REF:0000107 MGI:1859527 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
JBrowse link
G Nkx3-1 NK3 homeobox 1 involved_in ISO (PMID:20599703) RGD PMID:20599703 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441
JBrowse link
G Osm oncostatin M acts_upstream_of_or_within ISO (MGI:3036919|PMID:15012602) RGD PMID:15012602 MGI:3036919 NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313
JBrowse link
G Pdcd7 programmed cell death 7 acts_upstream_of_or_within ISO (MGI:1333591|PMID:10037816) RGD PMID:10037816 MGI:1333591 NCBI chr 8:65,862,604...65,877,333
Ensembl chr 8:65,862,387...65,877,333
JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within ISO MGI:1197015 (MGI:4942266|PMID:10684855) RGD PMID:10684855 MGI:4942266 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Prkcd protein kinase C, delta acts_upstream_of_or_within ISO (MGI:3581090|PMID:15731106) RGD PMID:15731106 MGI:3581090 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Pten phosphatase and tensin homolog acts_upstream_of_or_within ISO MGI:1857937 (MGI:2180890|PMID:9778245) RGD PMID:9778245 MGI:2180890 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G RGD1560831 similar to 40S ribosomal protein S3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:51,559,683...51,560,522
Ensembl chr 3:51,559,683...51,560,524
JBrowse link
G Rps3 ribosomal protein S3 involved_in IBA
ISO
PMID:21873635
(PMID:14988002)
RGD PMID:14988002 PMID:21873635 RGD:13792537 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO (PMID:18758450) RGD PMID:18758450 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 acts_upstream_of_or_within ISO MGI:1336991 (MGI:3612718|PMID:16044147) RGD PMID:16044147 MGI:3612718 NCBI chr 5:24,253,986...24,272,250
Ensembl chr 5:24,260,568...24,267,968
JBrowse link
G Tp63 tumor protein p63 acts_upstream_of_or_within ISO (MGI:1289874|PMID:9774969) RGD PMID:9774969 MGI:1289874 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
JBrowse link
G Tp73 tumor protein p73 acts_upstream_of_or_within ISO PR:Q9QXE4-2 (MGI:3612718|PMID:16044147) RGD PMID:16044147 MGI:3612718 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128
JBrowse link
G Tpd52l1 TPD52 like 1 involved_in ISO
IBA
(PMID:14761963)
PMID:21873635
RGD PMID:14761963 PMID:21873635 RGD:13792537 NCBI chr 1:26,172,038...26,290,704
Ensembl chr 1:26,172,170...26,291,109
JBrowse link
G Traf7 TNF receptor associated factor 7 involved_in ISO (PMID:15001576) RGD PMID:15001576 NCBI chr10:13,533,570...13,552,290
Ensembl chr10:13,533,570...13,552,203
JBrowse link
G Trim39 tripartite motif-containing 39 involved_in IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:19100260)
Ensembl
RGD
PMID:19100260 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr20:2,003,320...2,017,175
Ensembl chr20:1,983,533...2,020,117
JBrowse link
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
ISO
GO_REF:0000024
(MGI:5648772|PMID:26015568), (MGI:5796067|PMID:26949185)
UniProt
RGD
PMID:26015568 PMID:26949185 GO_REF:0000024 MGI:5648772 MGI:5796067 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO MGI:1913418 (MGI:5525071|PMID:22240901) RGD PMID:22240901 MGI:5525071 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO
IBA
(PMID:14676213)
PMID:21873635
UniProtKB:O55033 (MGI:5613475|PMID:16835242)
RGD PMID:14676213 PMID:16835242 PMID:21873635 MGI:5613475, RGD:13792537 NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300
JBrowse link
G Nck2 NCK adaptor protein 2 involved_in ISO
IBA
UniProtKB:Q99M51 (MGI:5613475|PMID:16835242)
PMID:21873635
RGD PMID:16835242 PMID:21873635 MGI:5613475, RGD:13792537 NCBI chr 9:45,713,979...45,840,330
Ensembl chr 9:45,714,883...45,840,307
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISO (MGI:5619464|PMID:21216966) RGD PMID:21216966 MGI:5619464 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627
JBrowse link
G Rnf183 ring finger protein 183 involved_in ISO
IBA
(PMID:29507230)
PMID:21873635
RGD PMID:29507230 PMID:21873635 RGD:13792537 NCBI chr 5:75,877,111...75,886,253
Ensembl chr 5:75,876,003...75,886,191
JBrowse link
G Serinc3 serine incorporator 3 acts_upstream_of_or_within ISO (MGI:2671011|PMID:12486168) RGD PMID:12486168 MGI:2671011 NCBI chr 3:152,301,882...152,321,327
Ensembl chr 3:152,301,772...152,321,808
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (MGI:5607229|PMID:20955178) RGD PMID:20955178 MGI:5607229 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Spop speckle type BTB/POZ protein acts_upstream_of_or_within ISO MGI:102851 (MGI:4836774|PMID:20811152) RGD PMID:20811152 MGI:4836774 NCBI chr10:80,358,121...80,438,983
Ensembl chr10:80,358,124...80,483,955
JBrowse link
positive regulation of extrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen involved_in ISO (PMID:10406457) RGD PMID:10406457 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtr2 angiotensin II receptor, type 2 involved_in ISO (PMID:10406457) RGD PMID:10406457 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057
JBrowse link
G Bcl10 BCL10, immune signaling adaptor involved_in
acts_upstream_of_or_within
IBA
ISO
ISS
PMID:21873635
(MGI:1355482|PMID:10753917)
GO_REF:0000024
(PMID:11466612)
RGD
UniProt
PMID:10753917 PMID:11466612 PMID:21873635 GO_REF:0000024 MGI:1355482, RGD:13792537 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523
JBrowse link
G Bcl2l14 Bcl2-like 14 involved_in ISO (PMID:11054413) RGD PMID:11054413 NCBI chr 4:167,217,561...167,258,723
Ensembl chr 4:167,219,871...167,258,086
JBrowse link
G Bid BH3 interacting domain death agonist involved_in IBA
ISO
PMID:21873635
(PMID:21459798)
RGD PMID:21459798 PMID:21873635 RGD:13792537 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Casp8 caspase 8 acts_upstream_of_or_within ISO MGI:1889507 (MGI:3603971|PMID:16183742) RGD PMID:16183742 MGI:3603971 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Cav1 caveolin 1 involved_in ISO (PMID:21382479) RGD PMID:21382479 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cyld CYLD lysine 63 deubiquitinase involved_in IBA
ISO
PMID:21873635
(PMID:21525013)
RGD PMID:21525013 PMID:21873635 RGD:13792537 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658
JBrowse link
G Dedd2 death effector domain containing 2 involved_in ISO (PMID:11741985) RGD PMID:11741985 NCBI chr 1:80,789,084...80,807,789
Ensembl chr 1:80,792,000...80,807,714
JBrowse link
G Fadd Fas associated via death domain involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1336166|MGI:2154952 (MGI:5486419|PMID:22675671)
(PMID:21525013)
RGD PMID:21525013 PMID:22675671 PMID:21873635 MGI:5486419, RGD:13792537 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G G0s2 G0/G1switch 2 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:19706769)
UniProt
RGD
PMID:19706769 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in IDA PMID:23907461 UniProt PMID:23907461 RGD:8553942 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
JBrowse link
G Hyal2 hyaluronidase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3851310|PMID:19366691)
Ensembl
RGD
PMID:19366691 GO_REF:0000107 MGI:3851310 NCBI chr 8:108,241,895...108,246,853
Ensembl chr 8:108,243,133...108,246,850
JBrowse link
G Itm2c integral membrane protein 2C involved_in ISO (MGI:4821078|PMID:14592447) RGD PMID:14592447 MGI:4821078 NCBI chr 9:86,545,927...86,559,745
Ensembl chr 9:86,545,921...86,559,742
JBrowse link
G Ltbr lymphotoxin beta receptor involved_in ISO (PMID:20732415) RGD PMID:20732415 NCBI chr 4:158,108,884...158,115,339
Ensembl chr 4:158,108,886...158,121,539
JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 involved_in ISO (PMID:19240112) RGD PMID:19240112 NCBI chr11:68,708,070...68,766,622
Ensembl chr11:68,707,969...68,768,816
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3578073|PMID:15858817)
Ensembl
RGD
PMID:15858817 GO_REF:0000107 MGI:3578073 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (PMID:21803845) RGD PMID:21803845 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:1857277 (MGI:80946|PMID:8666928) RGD PMID:8666928 MGI:80946 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:16964285) RGD PMID:16964285 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:5000222 (MGI:4437982|PMID:19136968)
Ensembl
RGD
PMID:19136968 GO_REF:0000107 MGI:4437982 NCBI chr 3:140,789,079...140,806,017
Ensembl chr 3:140,789,080...140,806,005
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in
acts_upstream_of_or_within
ISO (PMID:21525013), (PMID:22274400)
MGI:104798 (MGI:5510543|PMID:19498109)
RGD PMID:19498109 PMID:21525013 PMID:22274400 MGI:5510543 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Runx3 RUNX family transcription factor 3 acts_upstream_of_or_within ISO MGI:2179229 (MGI:2177980|PMID:11955451) RGD PMID:11955451 MGI:2177980 NCBI chr 5:147,393,926...147,419,161
Ensembl chr 5:147,360,994...147,419,156
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 acts_upstream_of_or_within ISO MGI:3045799 (MGI:3040721|PMID:14976225) RGD PMID:14976225 MGI:3040721 NCBI chr16:68,575,763...68,613,905
Ensembl chr16:68,575,763...68,614,286
JBrowse link
G Siglec1 sialic acid binding Ig like lectin 1 acts_upstream_of_or_within ISO MGI:3617694 (MGI:5469747|PMID:23408841) RGD PMID:23408841 MGI:5469747 NCBI chr 3:118,287,988...118,307,125
Ensembl chr 3:118,287,988...118,306,850
JBrowse link
G Tnf tumor necrosis factor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A involved_in IBA
ISO
PMID:21873635
(PMID:21525013)
RGD PMID:21525013 PMID:21873635 RGD:13792537 NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045
JBrowse link
G Tnfsf10 TNF superfamily member 10 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:20097879), (PMID:21525171), (PMID:22266862)
PMID:21873635
(MGI:3576402|PMID:15632112)
RGD PMID:15632112 PMID:20097879 PMID:21525171 PMID:22266862 PMID:21873635 MGI:3576402, RGD:13792537 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tnfsf12 TNF superfamily member 12 involved_in ISO (PMID:21525013) RGD PMID:21525013 NCBI chr10:54,403,870...54,413,213
Ensembl chr10:54,403,870...54,413,213
JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in ISO (PMID:21525013) RGD PMID:21525013 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538
JBrowse link
G Wwox WW domain-containing oxidoreductase involved_in ISO (MGI:3851310|PMID:19366691) RGD PMID:19366691 MGI:3851310 NCBI chr19:42,432,141...43,360,278
Ensembl chr19:42,432,152...43,359,391
JBrowse link
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO (MGI:67275|PMID:8358790) RGD PMID:8358790 MGI:67275 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Ctnna1 catenin alpha 1 acts_upstream_of_or_within ISO MGI:2677796 (MGI:5315030|PMID:22411810) RGD PMID:22411810 MGI:5315030 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910
JBrowse link
G Dapk3 death-associated protein kinase 3 involved_in IMP PMID:21172653 UniProt PMID:21172653 RGD:8554227 NCBI chr 7:8,524,182...8,532,552
Ensembl chr 7:8,524,183...8,532,558
JBrowse link
G Htra2 HtrA serine peptidase 2 involved_in ISO (PMID:20125124) RGD PMID:20125124 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095
JBrowse link
G Inhba inhibin subunit beta A involved_in ISO
ISS
(PMID:8267637)
GO_REF:0000024
RGD
UniProt
PMID:8267637 GO_REF:0000024 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Jak3 Janus kinase 3 involved_in ISO (MGI:3719947|PMID:16020505) RGD PMID:16020505 MGI:3719947 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536
JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857478 (MGI:3038547|PMID:15039234)
Ensembl
RGD
PMID:15039234 GO_REF:0000107 MGI:3038547 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha acts_upstream_of_or_within ISO (MGI:2183839|PMID:12115603) RGD PMID:12115603 MGI:2183839 NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327
JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha acts_upstream_of_or_within ISO (MGI:2675215|PMID:12944463) RGD PMID:12944463 MGI:2675215 NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129
JBrowse link
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta involved_in ISO (PMID:21172653) RGD PMID:21172653 NCBI chr 8:51,195,860...51,228,442
Ensembl chr 8:51,186,717...51,228,485
JBrowse link
G Ret ret proto-oncogene involved_in ISO (PMID:10921886) RGD PMID:10921886 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176
JBrowse link
G Srpx sushi-repeat-containing protein, X-linked acts_upstream_of_or_within ISO MGI:3706175 (MGI:3703665|PMID:17088259) RGD PMID:17088259 MGI:3703665 NCBI chr  X:12,676,984...12,751,296
Ensembl chr  X:12,566,645...12,747,882
JBrowse link
G Tgfb2 transforming growth factor, beta 2 acts_upstream_of_or_within ISO (MGI:67124|PMID:8206089) RGD PMID:8206089 MGI:67124 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Unc5b unc-5 netrin receptor B involved_in IMP PMID:21172653 UniProt PMID:21172653 RGD:8554227 NCBI chr20:28,697,726...28,764,474
Ensembl chr20:28,697,726...28,764,537
JBrowse link
G Wwox WW domain-containing oxidoreductase acts_upstream_of_or_within ISO (MGI:3851310|PMID:19366691) RGD PMID:19366691 MGI:3851310 NCBI chr19:42,432,141...43,360,278
Ensembl chr19:42,432,152...43,359,391
JBrowse link
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1b bone morphogenetic protein receptor type 1B acts_upstream_of_or_within ISO MGI:1927616|MGI:95484 (MGI:3819026|PMID:18363966) RGD PMID:18363966 MGI:3819026 NCBI chr 2:230,538,252...230,871,077
Ensembl chr 2:230,541,558...230,871,368
JBrowse link
G Faf1 Fas associated factor 1 acts_upstream_of_or_within ISO (MGI:77677|PMID:8524870) RGD PMID:8524870 MGI:77677 NCBI chr 5:124,426,032...124,790,014
Ensembl chr 5:124,426,062...124,789,977
JBrowse link
G Mal mal, T-cell differentiation protein acts_upstream_of_or_within ISO (MGI:3687876|PMID:12776198) RGD PMID:12776198 MGI:3687876 NCBI chr 3:114,864,378...114,888,136
Ensembl chr 3:114,864,378...114,888,136
JBrowse link
G Pea15 proliferation and apoptosis adaptor protein 15 acts_upstream_of_or_within ISO (MGI:3687663|PMID:10588860) RGD PMID:10588860 MGI:3687663 NCBI chr13:84,657,815...84,667,437
Ensembl chr13:84,654,870...84,667,499
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:15705586) RGD PMID:15705586 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO (MGI:84500|PMID:8940094) RGD PMID:8940094 MGI:84500 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in ISO
IEA
(PMID:9391078)
GO_REF:0000107
RGD
Ensembl
PMID:9391078 GO_REF:0000107 NCBI chr16:68,575,763...68,613,905
Ensembl chr16:68,575,763...68,614,286
JBrowse link
G Skil SKI-like proto-oncogene acts_upstream_of_or_within ISO MGI:2387096 (MGI:1858539|PMID:10811619) RGD PMID:10811619 MGI:1858539 NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080
JBrowse link
G Stk3 serine/threonine kinase 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:104798|MGI:1928487|MGI:1929004 (MGI:4420852|PMID:20080598)
Ensembl
RGD
PMID:20080598 GO_REF:0000107 MGI:4420852 NCBI chr 7:66,053,209...66,323,292
Ensembl chr 7:66,052,345...66,323,233
JBrowse link
G Stk4 serine/threonine kinase 4 acts_upstream_of_or_within ISO MGI:104798|MGI:1928487 (MGI:4420852|PMID:20080598) RGD PMID:20080598 MGI:4420852 NCBI chr 3:152,745,958...152,827,747
Ensembl chr 3:152,745,681...152,827,744
JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:18726995) RGD PMID:18726995 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Trps1 transcriptional repressor GATA binding 1 acts_upstream_of_or_within ISO MGI:107191|MGI:95484 (MGI:3819026|PMID:18363966) RGD PMID:18363966 MGI:3819026 NCBI chr 7:81,916,668...82,142,733
Ensembl chr 7:81,921,601...82,141,905
JBrowse link
G Zswim2 zinc finger, SWIM-type containing 2 acts_upstream_of_or_within ISO (MGI:3692348|PMID:16522193) RGD PMID:16522193 MGI:3692348 NCBI chr 3:68,993,422...69,015,441
Ensembl chr 3:68,995,027...69,015,411
JBrowse link
positive regulation of intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:14963330), (PMID:21199865), (PMID:21262771)
MGI:2158306 (MGI:3692043|PMID:14502238)
UniProt
RGD
PMID:14502238 PMID:14963330 PMID:21199865 PMID:21262771 GO_REF:0000024 MGI:3692043 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 involved_in IMP
ISO
ISS
PMID:27031958
(PMID:17289999), (PMID:27031958)
GO_REF:0000024
RGD
UniProt
PMID:17289999 PMID:27031958 PMID:27031958 GO_REF:0000024, RGD:14390051 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcap31 B-cell receptor-associated protein 31 involved_in ISO (PMID:21183955) RGD PMID:21183955 NCBI chr  X:151,397,567...151,429,666
Ensembl chr  X:151,397,576...151,428,506
JBrowse link
G Bcl2l11 Bcl2-like 11 involved_in ISO (PMID:21671007) RGD PMID:21671007 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 involved_in ISO (PMID:17938203) RGD PMID:17938203 NCBI chr 1:15,088,436...15,117,666
Ensembl chr 1:15,070,894...15,148,832
JBrowse link
G Becn1 beclin 1 involved_in IMP
ISO
ISS
PMID:27031958
(PMID:27031958)
GO_REF:0000024
RGD
UniProt
PMID:27031958 PMID:27031958 GO_REF:0000024, RGD:14390051 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bid BH3 interacting domain death agonist involved_in IBA
ISO
PMID:21873635
(PMID:21262771)
RGD PMID:21262771 PMID:21873635 RGD:13792537 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
ISO
GO_REF:0000024
(MGI:5705719|PMID:23429263)
UniProt
RGD
PMID:23429263 GO_REF:0000024 MGI:5705719 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase acts_upstream_of_or_within ISO MGI:3793294 (MGI:3790365|PMID:17938250) RGD PMID:17938250 MGI:3790365 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
JBrowse link
G Cav1 caveolin 1 involved_in ISO (PMID:21382479) RGD PMID:21382479 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Clu clusterin involved_in ISS
ISO
GO_REF:0000024
(PMID:21567405)
UniProt
RGD
PMID:21567405 GO_REF:0000024 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cyct cytochrome c, testis acts_upstream_of_or_within ISO (MGI:3652666|PMID:16757556) RGD PMID:16757556 MGI:3652666 NCBI chr 3:61,290,090...61,297,158
Ensembl chr 3:60,913,562...61,297,158
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:27031958)
UniProt
RGD
PMID:27031958 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Dnm1l dynamin 1-like involved_in ISO (PMID:20850011) RGD PMID:20850011 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Ei24 EI24, autophagy associated transmembrane protein acts_upstream_of_or_within ISO (MGI:3764759|PMID:17981155) RGD PMID:17981155 MGI:3764759 NCBI chr 8:36,494,289...36,510,653
Ensembl chr 8:36,494,289...36,510,571
JBrowse link
G Fis1 fission, mitochondrial 1 involved_in ISO (PMID:21183955) RGD PMID:21183955 NCBI chr12:19,708,558...19,723,392
Ensembl chr12:19,708,558...19,723,377
JBrowse link
G Flcn folliculin acts_upstream_of_or_within ISO MGI:4348628 (MGI:5050037|PMID:21258407) RGD PMID:21258407 MGI:5050037 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
G Gsdme gasdermin E involved_in ISO (PMID:21522185) RGD PMID:21522185 NCBI chr 4:79,258,799...79,321,129
Ensembl chr 4:79,257,804...79,320,806
JBrowse link
G Il19 interleukin 19 acts_upstream_of_or_within ISO MGI:3605069 (MGI:5491082|PMID:23468852) RGD PMID:23468852 MGI:5491082 NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473
JBrowse link
G Il20ra interleukin 20 receptor subunit alpha acts_upstream_of_or_within ISO MGI:1890472 (MGI:5491082|PMID:23468852) RGD PMID:23468852 MGI:5491082 NCBI chr 1:14,424,215...14,494,226
Ensembl chr 1:14,451,228...14,493,602
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase involved_in ISO
IEA
(PMID:16116473)
GO_REF:0000107
RGD
Ensembl
PMID:16116473 GO_REF:0000107 NCBI chr 5:141,888,319...141,916,992
Ensembl chr 5:141,888,326...141,903,794
JBrowse link
G Mir16 microRNA 16 involved_in ISO RNAcentral:URS00003D1AE3_9606 (PMID:16166262) RGD PMID:16166262 NCBI chr 2:153,245,349...153,245,443
Ensembl chr 2:153,245,349...153,245,443
JBrowse link
G Mir27b microRNA 27b acts_upstream_of_or_within ISO UniProtKB:P01375 (PMID:31124343) RGD PMID:31124343 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529
JBrowse link
G Nkx3-1 NK3 homeobox 1 involved_in ISO
ISS
(PMID:17486276)
GO_REF:0000024
RGD
UniProt
PMID:17486276 GO_REF:0000024 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator involved_in ISO
ISS
IMP
(PMID:27031958)
GO_REF:0000024
RGD
UniProt
PMID:27031958 PMID:27031958 GO_REF:0000024, RGD:14390051 NCBI chr 1:181,213,292...181,215,327 JBrowse link
G Plagl2 PLAG1 like zinc finger 2 acts_upstream_of_or_within ISO (MGI:2179174|PMID:11832486) RGD PMID:11832486 MGI:2179174 NCBI chr 3:141,695,322...141,708,567
Ensembl chr 3:141,695,322...141,708,503
JBrowse link
G Plekhf1 pleckstrin homology and FYVE domain containing 1 acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:3611133|PMID:16188880)
PMID:21873635
RGD PMID:16188880 PMID:21873635 MGI:3611133, RGD:13792537 NCBI chr 1:90,908,304...90,915,862
Ensembl chr 1:90,904,742...90,915,820
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:21454712) RGD PMID:21454712 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Prkra protein activator of interferon induced protein kinase EIF2AK2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:2386461|PMID:12181197)
Ensembl
RGD
PMID:12181197 GO_REF:0000107 MGI:2386461 NCBI chr 3:61,575,447...61,594,393
Ensembl chr 3:61,575,447...61,594,347
JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in ISO (PMID:19767770) RGD PMID:19767770 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 acts_upstream_of_or_within ISO (MGI:1345788|PMID:10490590) RGD PMID:10490590 MGI:1345788 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121
JBrowse link
G S100a8 S100 calcium binding protein A8 involved_in ISS
ISO
GO_REF:0000024
(PMID:19935772)
UniProt
RGD
PMID:19935772 GO_REF:0000024 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
JBrowse link
G S100a9 S100 calcium binding protein A9 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:19935772)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:19935772 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
JBrowse link
G Septin4 septin 4 involved_in ISO (PMID:21185211) RGD PMID:21185211 NCBI chr10:72,366,729...72,390,764
Ensembl chr10:72,366,873...72,390,768
JBrowse link
G Siah1 siah E3 ubiquitin protein ligase 1 involved_in ISO (PMID:21185211) RGD PMID:21185211 NCBI chr19:20,378,908...20,402,512
Ensembl chr19:20,378,439...20,403,808
JBrowse link
G Slc9a3r1 SLC9A3 regulator 1 involved_in ISO (PMID:20012548) RGD PMID:20012548 NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598
JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 involved_in ISO
IBA
(PMID:21262771), (PMID:24709986)
PMID:21873635
RGD PMID:21262771 PMID:24709986 PMID:21873635 RGD:13792537 NCBI chr12:20,907,410...20,940,232
Ensembl chr12:20,907,435...20,939,752
JBrowse link
G Taf6 TATA-box binding protein associated factor 6 involved_in ISO (PMID:20096117) RGD PMID:20096117 NCBI chr12:17,055,864...17,064,244
Ensembl chr12:17,055,873...17,064,247
JBrowse link
G Tp53 tumor protein p53 involved_in ISS
ISO
IMP
GO_REF:0000024
(PMID:14963330), (PMID:27031958)
UniProt
RGD
PMID:14963330 PMID:27031958 PMID:27031958 GO_REF:0000024, RGD:14390051 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif5a eukaryotic translation initiation factor 5A involved_in ISO (PMID:15371445) RGD PMID:15371445 NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656
JBrowse link
G Mir186 microRNA 186 acts_upstream_of ISO (PMID:27714074) RGD PMID:27714074 NCBI chr 2:246,582,806...246,582,891
Ensembl chr 2:246,582,806...246,582,891
JBrowse link
G Msx1 msh homeobox 1 involved_in ISO (PMID:15705871) RGD PMID:15705871 NCBI chr14:72,961,170...72,964,970
Ensembl chr14:72,961,148...72,964,966
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO (PMID:10962037) RGD PMID:10962037 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Rpl11 ribosomal protein L11 involved_in ISO (MGI:5883206|PMID:22262176) RGD PMID:22262176 MGI:5883206 NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599
JBrowse link
G Rps7 ribosomal protein S7 involved_in ISO (PMID:17310983) RGD PMID:17310983 NCBI chr 6:45,266,200...45,271,064
Ensembl chr 6:45,223,980...45,271,145
JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 involved_in ISO (MGI:5553386|PMID:24523556) RGD PMID:24523556 MGI:5553386 NCBI chr 2:233,750,838...233,784,817
Ensembl chr 2:233,750,838...233,784,784
JBrowse link
G Ubb ubiquitin B acts_upstream_of_or_within ISO (PMID:17571083) RGD PMID:17571083 NCBI chr10:47,247,629...47,249,335
Ensembl chr10:47,245,637...47,249,333
JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbh1 F-box DNA helicase 1 acts_upstream_of_or_within ISO (PMID:23361013) RGD PMID:23361013 NCBI chr17:66,749,506...66,787,590
Ensembl chr17:66,749,534...66,787,590
JBrowse link
G Mtch2 mitochondrial carrier 2 acts_upstream_of_or_within ISO MGI:2449949|MGI:5566664 (MGI:5662300|PMID:26219591) RGD PMID:26219591 MGI:5662300 NCBI chr 3:76,830,549...76,850,189
Ensembl chr 3:76,830,413...76,850,189
JBrowse link
G Nacc2 NACC family member 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:22926524)
Ensembl
RGD
PMID:22926524 GO_REF:0000107 NCBI chr 3:8,879,952...8,946,660
Ensembl chr 3:8,883,065...8,946,660
JBrowse link
G Pias4 protein inhibitor of activated STAT, 4 acts_upstream_of_or_within ISO (MGI:5009403|PMID:16816390) RGD PMID:16816390 MGI:5009403 NCBI chr 7:8,546,312...8,559,838
Ensembl chr 7:8,546,312...8,559,808
JBrowse link
G Plscr1 phospholipid scramblase 1 acts_upstream_of_or_within ISO (MGI:5284813|PMID:12509439) RGD PMID:12509439 MGI:5284813 NCBI chr 8:92,784,279...92,804,698
Ensembl chr 8:92,784,356...92,804,692
JBrowse link
G Rad9a RAD9 checkpoint clamp component A acts_upstream_of_or_within ISO MGI:2442925 (MGI:3584078|PMID:15983387) RGD PMID:15983387 MGI:3584078 NCBI chr 1:201,488,511...201,553,582
Ensembl chr 1:201,487,136...201,553,608
JBrowse link
G Rps3 ribosomal protein S3 involved_in ISO (PMID:22510408) RGD PMID:22510408 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680
JBrowse link
G Skil SKI-like proto-oncogene acts_upstream_of_or_within ISO MGI:2387096 (MGI:1858539|PMID:10811619) RGD PMID:10811619 MGI:1858539 NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080
JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpl26 ribosomal protein L26 involved_in ISO
IEA
(PMID:16213212)
GO_REF:0000107
(MGI:5882892|PMID:16213212)
RGD
Ensembl
PMID:16213212 GO_REF:0000107 MGI:5882892 NCBI chr10:53,610,836...53,613,966
Ensembl chr10:53,610,421...53,613,966
JBrowse link
G Steap3 STEAP3 metalloreductase acts_upstream_of_or_within ISO MGI:4398911 (MGI:4367682|PMID:18617898) RGD PMID:18617898 MGI:4367682 NCBI chr13:31,351,954...31,397,344
Ensembl chr13:31,351,954...31,396,519
JBrowse link
G Tp73 tumor protein p73 acts_upstream_of_or_within ISO MGI:2442925|MGI:98834 (MGI:3584078|PMID:15983387) RGD PMID:15983387 MGI:3584078 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128
JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death involved_in ISO (PMID:21716255)
(MGI:5474549|PMID:21716255)
RGD PMID:21716255 MGI:5474549 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nox1 NADPH oxidase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3616995 (MGI:4881403|PMID:19661248)
Ensembl
RGD
PMID:19661248 GO_REF:0000107 MGI:4881403 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236
JBrowse link
G Park7 Parkinsonism associated deglycase acts_upstream_of_or_within ISO (MGI:5543357|PMID:22555455) RGD PMID:22555455 MGI:5543357 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Sfpq splicing factor proline and glutamine rich involved_in ISO (PMID:15790595) RGD PMID:15790595 NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472
JBrowse link
G Sod1 superoxide dismutase 1 involved_in ISO (PMID:12551919) RGD PMID:12551919 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Vnn1 vanin 1 involved_in ISO (MGI:3052282|PMID:15282320) RGD PMID:15282320 MGI:3052282 NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
JBrowse link
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:23858059)
(MGI:5543313|PMID:23858059)
RGD PMID:23858059 MGI:5543313 NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in ISO UniProtKB:Q9WVS6 (PMID:23858059)
(MGI:5543313|PMID:23858059)
RGD PMID:23858059 MGI:5543313 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Ralbp1 ralA binding protein 1 IMP RGD PMID:23788031 RGD:12904719 NCBI chr 9:105,456,425...105,492,711
Ensembl chr 9:105,456,425...105,492,707
JBrowse link
positive regulation of TRAIL-activated apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf3 activating transcription factor 3 involved_in ISO (PMID:24939851) RGD PMID:24939851 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (PMID:19962668) RGD PMID:19962668 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 involved_in ISO
IEA
(PMID:19962668)
GO_REF:0000107
RGD
Ensembl
PMID:19962668 GO_REF:0000107 NCBI chr 7:17,520,827...17,571,871
Ensembl chr 7:17,521,919...17,571,839
JBrowse link
regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISO (PMID:23000344) RGD PMID:23000344 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Erp29 endoplasmic reticulum protein 29 involved_in ISO (MGI:5613446|PMID:24370996) RGD PMID:24370996 MGI:5613446 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in ISO (MGI:5613477|PMID:15147274) RGD PMID:15147274 MGI:5613477 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
JBrowse link
regulation of extrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl5 acyl-CoA synthetase long-chain family member 5 involved_in ISO (PMID:17681178) RGD PMID:17681178 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
JBrowse link
G Bcl2l12 Bcl2 like 12 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:95,472,272...95,480,991
Ensembl chr 1:95,472,272...95,480,991
JBrowse link
G Bcl2l14 Bcl2-like 14 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:167,217,561...167,258,723
Ensembl chr 4:167,219,871...167,258,086
JBrowse link
G Dbh dopamine beta-hydroxylase involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857556 (MGI:3587974|PMID:15849236)
Ensembl
RGD
PMID:15849236 GO_REF:0000107 MGI:3587974 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
JBrowse link
G Deptor DEP domain containing MTOR-interacting protein involved_in ISO (PMID:19446321) RGD PMID:19446321 NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773
JBrowse link
G Madd MAP-kinase activating death domain involved_in ISO (PMID:11577081) RGD PMID:11577081 NCBI chr 3:77,114,330...77,157,865
Ensembl chr 3:77,114,314...77,157,701
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO (MGI:72948|PMID:7743522) RGD PMID:7743522 MGI:72948 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Traf1 TNF receptor-associated factor 1 involved_in ISO (PMID:10692572) RGD PMID:10692572 NCBI chr 3:18,222,024...18,242,163
Ensembl chr 3:18,222,054...18,241,807
JBrowse link
regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO MGI:2176216|MGI:2181474 (MGI:3608262|PMID:16207751), (MGI:3775898|PMID:18191119) RGD PMID:16207751 PMID:18191119 MGI:3608262 MGI:3775898 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
JBrowse link
regulation of extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fem1b fem-1 homolog B involved_in ISO (PMID:10542291) RGD PMID:10542291 NCBI chr 8:63,265,301...63,278,577
Ensembl chr 8:63,265,301...63,278,577
JBrowse link
G Lgals3 galectin 3 involved_in ISO (PMID:8692888) RGD PMID:8692888 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
JBrowse link
G Madd MAP-kinase activating death domain involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:9115275)
UniProt
Ensembl
RGD
PMID:9115275 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:77,114,330...77,157,865
Ensembl chr 3:77,114,314...77,157,701
JBrowse link
G Sp100 SP100 nuclear antigen involved_in ISO (PMID:17245429) RGD PMID:17245429 NCBI chr 9:86,310,990...86,377,036
Ensembl chr 9:86,311,032...86,377,034
JBrowse link
G Stx4 syntaxin 4 involved_in ISO (PMID:20956541) RGD PMID:20956541 NCBI chr 1:182,451,108...182,459,701
Ensembl chr 1:182,451,117...182,459,979
JBrowse link
G Tmc8 transmembrane channel-like 8 involved_in ISO (PMID:23429285) RGD PMID:23429285 NCBI chr10:103,000,038...103,010,601
Ensembl chr10:102,998,402...103,010,590
JBrowse link
regulation of intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyld CYLD lysine 63 deubiquitinase involved_in ISO
IBA
(PMID:21525013)
PMID:21873635
RGD PMID:21525013 PMID:21873635 RGD:13792537 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658
JBrowse link
G Dapk2 death-associated protein kinase 2 involved_in ISO (PMID:10376525) RGD PMID:10376525 NCBI chr 8:66,706,536...66,825,567
Ensembl chr 8:66,706,609...66,825,567
JBrowse link
G Ptpmt1 protein tyrosine phosphatase, mitochondrial 1 involved_in ISO
IEA
UniProtKB:Q9Y6J8 (PMID:24709986)
GO_REF:0000107
RGD
Ensembl
PMID:24709986 GO_REF:0000107 NCBI chr 3:76,889,922...76,899,427
Ensembl chr 3:76,889,922...76,899,427
JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:14730312) RGD PMID:14730312 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 involved_in ISO UniProtKB:Q8WUK0 (PMID:24709986) RGD PMID:24709986 NCBI chr12:20,907,410...20,940,232
Ensembl chr12:20,907,435...20,939,752
JBrowse link
regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd2 ankyrin repeat domain 2 acts_upstream_of_or_within ISO (MGI:3796961|PMID:18302940) RGD PMID:18302940 MGI:3796961 NCBI chr 1:240,847,111...240,856,563
Ensembl chr 1:240,847,072...240,856,566
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO (MGI:3818156|PMID:17571083) RGD PMID:17571083 MGI:3818156 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnrnpk heterogeneous nuclear ribonucleoprotein K acts_upstream_of_or_within ISO (MGI:4881379|PMID:20673990) RGD PMID:20673990 MGI:4881379 NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997
JBrowse link
regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P4hb prolyl 4-hydroxylase subunit beta involved_in ISO (PMID:12095988) RGD PMID:12095988 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
JBrowse link
G Ubqln1 ubiquilin 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:12095988)
GO_REF:0000107
HGNC
RGD
Ensembl
PMID:12095988 GO_REF:0000024 GO_REF:0000107 NCBI chr17:6,439,002...6,477,096
Ensembl chr17:6,439,002...6,477,090
JBrowse link
regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp1 poly (ADP-ribose) polymerase 1 IMP RGD PMID:17347665 RGD:10414071 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6458378|PMID:30684126) RGD PMID:30684126 MGI:6458378 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20099
    response to stimulus 10542
      regulation of response to stimulus 4142
        regulation of signal transduction 3121
          regulation of apoptotic signaling pathway 422
            negative regulation of apoptotic signaling pathway + 255
            positive regulation of apoptotic signaling pathway + 165
            regulation of extrinsic apoptotic signaling pathway + 171
            regulation of intrinsic apoptotic signaling pathway + 189
Path 2
Term Annotations click to browse term
  biological_process 20099
    biological regulation 13928
      regulation of biological process 13160
        regulation of cellular process 12438
          regulation of cell death 1892
            regulation of programmed cell death 1703
              regulation of apoptotic process 1669
                regulation of apoptotic signaling pathway 422
                  negative regulation of apoptotic signaling pathway + 255
                  positive regulation of apoptotic signaling pathway + 165
                  regulation of extrinsic apoptotic signaling pathway + 171
                  regulation of intrinsic apoptotic signaling pathway + 189
paths to the root