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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of hematopoietic stem cell differentiation
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Accession:GO:1902036 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation.
Synonyms:exact_synonym: regulation of haematopoietic stem cell differentiation;   regulation of haemopoietic stem cell differentiation;   regulation of hemopoietic stem cell differentiation
 xref: Reactome:R-HSA-8939236 "RUNX1 regulates transcription of genes involved in differentiation of HSCs"


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regulation of hematopoietic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDK6 cyclin dependent kinase 6 acts_upstream_of_or_within ISO (PMID:25342715) MGI PMID:25342715 NCBI chr14:18,178,352...18,413,869
Ensembl chr14:18,188,429...18,419,869 		JBrowse link
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:29,494,641...29,537,933
Ensembl chr17:29,496,128...29,537,933 		JBrowse link
G KAT5 lysine acetyltransferase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:51,499,615...51,507,434
Ensembl chr18:51,499,938...51,576,699 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in ISS UniProt GO_REF:0000024 NCBI chr29:24,904...243,926
Ensembl chr29:35,007...243,895 		JBrowse link
G PUS7 pseudouridine synthase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:14,882,276...14,939,070
Ensembl chr18:14,878,034...14,938,537 		JBrowse link
G SETD1A SET domain containing 1A, histone lysine methyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:17,224,107...17,246,527
Ensembl chr 6:17,224,694...17,245,870 		JBrowse link
G YTHDF2 YTH N6-methyladenosine RNA binding protein F2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:71,760,232...71,791,420
Ensembl chr 2:71,760,312...71,792,527 		JBrowse link
negative regulation of hematopoietic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA9 heat shock protein family A (Hsp70) member 9 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:26,122,917...26,142,458
Ensembl chr11:26,121,499...26,142,434 		JBrowse link
G LOC100683370 thymosin beta-4 involved_in ISO (PMID:7694679) UniProt PMID:7694679 NCBI chr 1:21,127,694...21,128,346 JBrowse link
G N4BP2L2 NEDD4 binding protein 2 like 2 involved_in ISO (PMID:19506020) UniProt PMID:19506020 NCBI chr25:7,622,032...7,694,396
Ensembl chr25:7,623,670...7,694,398 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:20,989,205...21,087,044
Ensembl chr36:20,989,360...21,012,524 		JBrowse link
G TCF15 transcription factor 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:20,274,113...20,281,081
Ensembl chr24:20,274,050...20,280,270 		JBrowse link
G ZFP36 ZFP36 ring finger protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11588035) Ensembl
MGI		 PMID:11588035 GO_REF:0000107 NCBI chr 1:113,815,972...113,818,093
Ensembl chr 1:113,816,273...113,818,065 		JBrowse link
positive regulation of hematopoietic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXC1 forkhead box C1 involved_in ISO (PMID:24590069) UniProt PMID:24590069
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22099
    developmental process 6889
      regulation of developmental process 2723
        regulation of cell differentiation 1757
          regulation of hematopoietic progenitor cell differentiation 42
            regulation of hematopoietic stem cell differentiation 14
              negative regulation of hematopoietic stem cell differentiation 6
              positive regulation of hematopoietic stem cell differentiation 1
Path 2
Term Annotations click to browse term
  biological_process 22099
    cellular process 21628
      cellular developmental process 4647
        cell differentiation 4646
          cell development 3281
            hemopoiesis 1058
              hematopoietic progenitor cell differentiation 180
                regulation of hematopoietic progenitor cell differentiation 42
                  regulation of hematopoietic stem cell differentiation 14
                    negative regulation of hematopoietic stem cell differentiation 6
                    positive regulation of hematopoietic stem cell differentiation 1
paths to the root