TCF15 (transcription factor 15) - Rat Genome Database

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Gene: TCF15 (transcription factor 15) Canis lupus familiaris
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Symbol: TCF15
Name: transcription factor 15
RGD ID: 12380678
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); ear development (ortholog); establishment of epithelial cell apical/basal polarity (ortholog); ASSOCIATED WITH Brown-Vialetto-Van Laere syndrome 1 (ortholog); Neurodevelopmental Disorders (ortholog); polycystic ovary syndrome (ortholog); FOUND IN nucleus (inferred); RNA polymerase II transcription regulator complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: PARAXIS; transcription factor 15 (basic helix-loop-helix)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12420,274,113 - 20,281,081 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2420,274,050 - 20,280,270 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2419,925,930 - 19,932,479 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02420,965,005 - 20,971,592 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2420,964,975 - 20,971,210 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12420,240,077 - 20,246,616 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02420,345,815 - 20,352,308 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02420,776,922 - 20,783,474 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:25403511   PMID:30032202  


Genomics

Comparative Map Data
TCF15
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12420,274,113 - 20,281,081 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2420,274,050 - 20,280,270 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2419,925,930 - 19,932,479 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02420,965,005 - 20,971,592 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2420,964,975 - 20,971,210 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12420,240,077 - 20,246,616 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02420,345,815 - 20,352,308 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02420,776,922 - 20,783,474 (+)NCBIUU_Cfam_GSD_1.0
TCF15
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3820604,257 - 610,309 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl20604,257 - 610,309 (-)EnsemblGRCh38hg38GRCh38
GRCh3720584,901 - 590,953 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3620532,637 - 538,910 (-)NCBINCBI36Build 36hg18NCBI36
Build 3420532,636 - 538,910NCBI
Celera20679,462 - 685,735 (-)NCBICelera
Cytogenetic Map20p13NCBI
HuRef20535,944 - 542,217 (-)NCBIHuRef
CHM1_120584,649 - 590,913 (-)NCBICHM1_1
T2T-CHM13v2.020647,994 - 654,046 (-)NCBIT2T-CHM13v2.0
Tcf15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392151,984,973 - 151,991,017 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2151,985,481 - 151,991,017 (+)EnsemblGRCm39 Ensembl
GRCm382152,143,056 - 152,149,097 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2152,143,561 - 152,149,097 (+)EnsemblGRCm38mm10GRCm38
MGSCv372151,969,345 - 151,974,833 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362151,835,013 - 151,840,538 (+)NCBIMGSCv36mm8
Celera2157,959,706 - 157,965,194 (+)NCBICelera
Cytogenetic Map2G3NCBI
cM Map274.83NCBI
Tcf15
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83161,099,301 - 161,105,083 (+)NCBIGRCr8
mRatBN7.23140,638,984 - 140,644,766 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3140,638,984 - 140,644,766 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3144,543,478 - 144,549,262 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03153,127,302 - 153,133,086 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03150,867,901 - 150,873,677 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03147,643,250 - 147,649,511 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3147,643,250 - 147,649,504 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03153,992,077 - 153,998,338 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43142,491,664 - 142,497,446 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13142,397,247 - 142,402,918 (+)NCBI
Celera3139,391,601 - 139,397,369 (+)NCBICelera
Cytogenetic Map3q41NCBI
Tcf15
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955597446,855 - 451,949 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955597446,489 - 452,003 (-)NCBIChiLan1.0ChiLan1.0
TCF15
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2211,692,066 - 1,698,139 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1201,688,894 - 1,694,967 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v020811,907 - 817,971 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.120581,915 - 587,644 (-)NCBIpanpan1.1PanPan1.1panPan2
TCF15
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1734,626,670 - 34,633,263 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11734,626,682 - 34,632,881 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21739,268,048 - 39,274,562 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TCF15
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1255,909,945 - 55,916,186 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl255,910,030 - 55,915,600 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660788,037,064 - 8,043,307 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tcf15
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247411,689,431 - 1,694,815 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247411,689,397 - 1,694,934 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TCF15
99 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000011122   ⟹   ENSCAFP00000010303
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2420,274,050 - 20,280,270 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845027908   ⟹   ENSCAFP00845021967
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2420,964,975 - 20,971,210 (+)Ensembl
RefSeq Acc Id: XM_038433393   ⟹   XP_038289321
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02420,965,005 - 20,971,592 (+)NCBI
RefSeq Acc Id: XM_038508596   ⟹   XP_038364524
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12420,240,077 - 20,246,616 (+)NCBI
RefSeq Acc Id: XM_038571887   ⟹   XP_038427815
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02420,776,922 - 20,783,474 (+)NCBI
RefSeq Acc Id: XM_038636141   ⟹   XP_038492069
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02420,345,815 - 20,352,308 (+)NCBI
RefSeq Acc Id: XM_846968   ⟹   XP_852061
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12420,274,113 - 20,281,081 (+)NCBI
Dog10K_Boxer_Tasha2419,925,930 - 19,932,479 (+)NCBI
Sequence:
RefSeq Acc Id: XP_852061   ⟸   XM_846968
- UniProtKB: A0A8C0MM43 (UniProtKB/TrEMBL),   A0A8I3RYY1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000010303   ⟸   ENSCAFT00000011122
RefSeq Acc Id: XP_038364524   ⟸   XM_038508596
RefSeq Acc Id: XP_038492069   ⟸   XM_038636141
RefSeq Acc Id: XP_038289321   ⟸   XM_038433393
- UniProtKB: A0A8C0MM43 (UniProtKB/TrEMBL),   A0A8I3RYY1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038427815   ⟸   XM_038571887
- UniProtKB: A0A8C0MM43 (UniProtKB/TrEMBL),   A0A8I3RYY1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845021967   ⟸   ENSCAFT00845027908
Protein Domains
bHLH

Promoters
RGD ID:13687549
Promoter ID:EPDNEW_C5617
Type:single initiation site
Name:TCF15_1
Description:transcription factor 15
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12420,274,096 - 20,274,156EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000006930 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030006466 UniProtKB/TrEMBL
  ENSCAFG00040020072 UniProtKB/TrEMBL
  ENSCAFG00845015657 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000011122.6 UniProtKB/TrEMBL
  ENSCAFT00030011890.1 UniProtKB/TrEMBL
  ENSCAFT00040037088.1 UniProtKB/TrEMBL
  ENSCAFT00845027908 ENTREZGENE
  ENSCAFT00845027908.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/TrEMBL
  E-box_TF_Regulators UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report cfa:609667 UniProtKB/TrEMBL
NCBI Gene TCF15 ENTREZGENE
PANTHER BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR 15 UniProtKB/TrEMBL
Pfam HLH UniProtKB/TrEMBL
PROSITE BHLH UniProtKB/TrEMBL
SMART HLH UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/TrEMBL
UniProt A0A8C0MM43 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RYY1 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:47190 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-03-08 TCF15  transcription factor 15    transcription factor 15 (basic helix-loop-helix)  Symbol and/or name change 5135510 APPROVED