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ONTOLOGY REPORT - ANNOTATIONS

Term:modulation of inhibitory postsynaptic potential
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Accession:GO:0098828 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.
Synonyms:exact_synonym: regulation of inhibitory postsynaptic potential

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modulation of inhibitory postsynaptic potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit ISO MMO:0000293 RGD PMID:19385992 RGD:152995360 NCBI chrNW_004624758:22,182,468...22,200,076
Ensembl chrNW_004624758:22,182,951...22,200,063 		JBrowse link
G Dbn1 drebrin 1 ISO RGD PMID:19174472 RGD:10398809 NCBI chrNW_004624733:12,616,537...12,631,967
Ensembl chrNW_004624733:12,616,423...12,632,133 		JBrowse link
G Drd4 dopamine receptor D4 ISO RGD PMID:12417643 RGD:401960856 NCBI chrNW_004624766:21,834,093...21,837,314
Ensembl chrNW_004624766:21,834,169...21,836,710 		JBrowse link
positive regulation of inhibitory postsynaptic potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase ISO RGD PMID:11495935 RGD:10047060 NCBI chrNW_004624824:6,112,644...6,202,936
Ensembl chrNW_004624824:6,141,213...6,202,936 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:29339324 RGD:401940161 NCBI chrNW_004624824:7,128,169...7,513,360
Ensembl chrNW_004624824:7,137,909...7,507,910 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B ISO RGD PMID:29339324 RGD:401940161 NCBI chrNW_004624752:24,008,520...24,480,834
Ensembl chrNW_004624752:24,135,487...24,459,288 		JBrowse link
G Igsf9b immunoglobulin superfamily member 9B acts_upstream_of_or_within ISO (PMID:23751499) MGI PMID:23751499 NCBI chrNW_004624812:8,436,525...8,514,435
Ensembl chrNW_004624812:8,470,958...8,514,368 		JBrowse link
G Nlgn2 neuroligin 2 involved_in ISO PMID:18550748
(PMID:15620359), (PMID:17582332)		 BHF-UCL PMID:15620359 PMID:17582332 PMID:18550748 RGD:8554527 NCBI chrNW_004624786:10,019,307...10,034,624
Ensembl chrNW_004624786:10,022,717...10,034,624 		JBrowse link
G Nlgn3 neuroligin 3 ISO RGD PMID:19406211 RGD:8554851 NCBI chrNW_004624903:1,437,663...1,465,955
Ensembl chrNW_004624903:1,438,428...1,463,172 		JBrowse link
G Ntsr1 neurotensin receptor 1 ISO RGD PMID:15664687 RGD:9831120 NCBI chrNW_004624741:28,504,814...28,543,592
Ensembl chrNW_004624741:28,505,037...28,544,122 		JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 involved_in ISO (PMID:21262469) ParkinsonsUK-UCL PMID:21262469 NCBI chrNW_004624763:20,027,601...20,567,288
Ensembl chrNW_004624763:20,027,574...20,567,688 		JBrowse link
G Unc13b unc-13 homolog B involved_in ISO PMID:21262469 ParkinsonsUK-UCL PMID:21262469 RGD:10047275 NCBI chrNW_004624915:327,633...530,522
Ensembl chrNW_004624915:327,401...531,886 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15113
    cellular process 14725
      signal transduction 5410
        regulation of signal transduction 2866
          modulation of inhibitory postsynaptic potential 12
            positive regulation of inhibitory postsynaptic potential 9
Path 2
Term Annotations click to browse term
  biological_process 15113
    biological regulation 10690
      regulation of biological process 10352
        signaling 5896
          cell-cell signaling 1262
            synaptic signaling 819
              trans-synaptic signaling 788
                anterograde trans-synaptic signaling 780
                  chemical synaptic transmission 780
                    chemical synaptic transmission, postsynaptic 127
                      inhibitory postsynaptic potential 25
                        modulation of inhibitory postsynaptic potential 12
                          positive regulation of inhibitory postsynaptic potential 9
paths to the root