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ONTOLOGY REPORT - ANNOTATIONS


Term:inhibitory postsynaptic potential
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Accession:GO:0060080 term browser browse the term
Definition:A process that causes a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.
Synonyms:exact_synonym: regulation of inhibitory post-synaptic membrane potential
 related_synonym: IPSP


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inhibitory postsynaptic potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor acts_upstream_of_or_within ISO MGI:95815 (MGI:1354133|PMID:10704492) RGD PMID:10704492 MGI:1354133 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Adrb1 adrenoceptor beta 1 IMP RGD PMID:18262504 RGD:5129137 NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Bdnf brain-derived neurotrophic factor acts_upstream_of_or_within ISO MGI:2176750 (MGI:5559620|PMID:24201284) RGD PMID:24201284 MGI:5559620 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit acts_upstream_of_or_within ISO MGI:3700204|MGI:3700205 (MGI:3699045|PMID:17146052) RGD PMID:17146052 MGI:3699045 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 IMP RGD PMID:19748551 RGD:4891944 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Drd4 dopamine receptor D4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2178631|MGI:3576789 (MGI:1934688|PMID:11356863), (MGI:3575384|PMID:14684868)
Ensembl
RGD
PMID:11356863 PMID:14684868 GO_REF:0000107 MGI:1934688 MGI:3575384 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 involved_in ISO (MGI:5619469|PMID:19846622) RGD PMID:19846622 MGI:5619469 NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961
JBrowse link
G Glra1 glycine receptor, alpha 1 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:5707576|PMID:24801766)
MGI:3696673 (MGI:3695847|PMID:17114051)
UniProt
RGD
PMID:17114051 PMID:24801766 GO_REF:0000024 MGI:3695847 MGI:5707576 NCBI chr10:39,625,853...39,727,897
Ensembl chr10:39,629,459...39,727,162
JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 acts_upstream_of_or_within ISO MGI:2176347|MGI:95815 (MGI:1927732|PMID:11144357), (MGI:2387276|PMID:12223554) RGD PMID:11144357 PMID:12223554 MGI:1927732 MGI:2387276 NCBI chr11:27,169,739...27,571,131
Ensembl chr11:27,169,740...27,570,645
JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 acts_upstream_of_or_within ISO MGI:1857979|MGI:95814|MGI:99402 (MGI:1327732|PMID:9880586), (MGI:1354133|PMID:10704492), (MGI:1927732|PMID:11144357), (MGI:2387276|PMID:12223554) RGD PMID:9880586 PMID:10704492 PMID:11144357 PMID:12223554 MGI:1327732 MGI:1354133 MGI:1927732 MGI:2387276 NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375
JBrowse link
G Insyn1 inhibitory synaptic factor 1 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(MGI:5800345|PMID:27609886)
UniProt
RGD
PMID:27609886 PMID:21873635 GO_REF:0000024 MGI:5800345, RGD:13792537 NCBI chr 8:58,904,153...58,914,850
Ensembl chr 8:58,904,153...58,914,843
JBrowse link
G Insyn2a inhibitory synaptic factor 2A involved_in IBA
ISO
PMID:21873635
(MGI:5800345|PMID:27609886)
RGD PMID:27609886 PMID:21873635 MGI:5800345, RGD:13792537 NCBI chr 1:189,697,856...189,753,194
Ensembl chr 1:189,697,878...189,752,922
JBrowse link
G Nlgn1 neuroligin 1 NOT|involved_in IDA
ISO
PMID:17582332
(MGI:3803801|PMID:17582332)
RGD PMID:17582332 PMID:17582332 MGI:3803801, RGD:8553502 NCBI chr 2:108,256,236...109,181,530
Ensembl chr 2:108,257,824...109,002,464
JBrowse link
G Nlgn3 neuroligin 3 involved_in
acts_upstream_of_or_within
IDA
ISO
PMID:19406211
(MGI:5286761|PMID:21808020)
MGI:3758949 (MGI:3758357|PMID:17823315)
RGD PMID:17823315 PMID:21808020 PMID:19406211 MGI:3758357 MGI:5286761, RGD:8554851 NCBI chr  X:66,427,926...66,457,378
Ensembl chr  X:66,429,458...66,451,876
JBrowse link
G Npas4 neuronal PAS domain protein 4 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:3826741|PMID:18815592), (MGI:5602898|PMID:24855953)
MGI:3828100 (MGI:5559620|PMID:24201284)
UniProt
RGD
PMID:18815592 PMID:24201284 PMID:24855953 GO_REF:0000024 MGI:3826741 MGI:5559620 MGI:5602898 NCBI chr 1:202,281,260...202,298,681
Ensembl chr 1:202,281,958...202,286,724
JBrowse link
modulation of inhibitory postsynaptic potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbn1 drebrin 1 IMP RGD PMID:19174472 RGD:10398809 NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984
JBrowse link
positive regulation of inhibitory postsynaptic potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IMP RGD PMID:11495935 RGD:10047060 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
JBrowse link
G Igsf9b immunoglobulin superfamily, member 9B acts_upstream_of_or_within ISO (MGI:5514300|PMID:23751499) RGD PMID:23751499 MGI:5514300 NCBI chr 8:25,712,644...25,769,481
Ensembl chr 8:25,712,644...25,758,554
JBrowse link
G Nlgn2 neuroligin 2 involved_in IEA
ISO
IMP
GO_REF:0000107
(MGI:3803801|PMID:17582332), (MGI:5284797|PMID:15620359)
PMID:18550748
Ensembl
RGD
PMID:15620359 PMID:17582332 PMID:18550748 GO_REF:0000107 MGI:3803801 MGI:5284797, RGD:8554527 NCBI chr10:54,544,588...54,557,854
Ensembl chr10:54,544,588...54,558,434
JBrowse link
G Nlgn3 neuroligin 3 IDA RGD PMID:19406211 RGD:8554851 NCBI chr  X:66,427,926...66,457,378
Ensembl chr  X:66,429,458...66,451,876
JBrowse link
G Ntsr1 neurotensin receptor 1 IMP RGD PMID:15664687 RGD:9831120 NCBI chr 3:167,606,215...167,656,377
Ensembl chr 3:167,606,215...167,656,377
JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 involved_in IGI
ISO
ISS
PMID:21262469
UniProtKB:Q99NE5|UniProtKB:Q9EQZ7 (MGI:4887275|PMID:21262469)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:21262469 PMID:21262469 GO_REF:0000024 MGI:4887275, RGD:10047275 NCBI chr 9:24,696,959...25,196,368
Ensembl chr 9:24,698,854...25,196,631
JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 involved_in ISS
ISO
GO_REF:0000024
UniProtKB:Q99NE5|UniProtKB:Q9EQZ7 (MGI:4887275|PMID:21262469)
ParkinsonsUK-UCL
RGD
PMID:21262469 GO_REF:0000024 MGI:4887275 NCBI chr 7:70,248,104...70,759,134
Ensembl chr 7:70,243,872...70,757,491
JBrowse link
G Unc13b unc-13 homolog B involved_in IGI PMID:21262469 ParkinsonsUK-UCL PMID:21262469 PMID:21262469 RGD:10047275, RGD:10047275 NCBI chr 5:57,288,999...57,504,110
Ensembl chr 5:57,289,227...57,502,926
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of biological quality 4181
        regulation of membrane potential 488
          regulation of postsynaptic membrane potential 162
            inhibitory postsynaptic potential 23
              modulation of inhibitory postsynaptic potential + 9
              positive regulation of inhibitory postsynaptic potential 8
Path 2
Term Annotations click to browse term
  biological_process 19492
    cellular process 18340
      cell communication 7543
        cell-cell signaling 1735
          synaptic signaling 919
            trans-synaptic signaling 892
              anterograde trans-synaptic signaling 883
                chemical synaptic transmission 883
                  chemical synaptic transmission, postsynaptic 127
                    inhibitory postsynaptic potential 23
                      modulation of inhibitory postsynaptic potential + 9
                      positive regulation of inhibitory postsynaptic potential 8
paths to the root