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ONTOLOGY REPORT - ANNOTATIONS

Term:alpha-glucosidase activity
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Accession:GO:0090599 term browser browse the term
Definition:Catalysis of the hydrolysis of terminal, non-reducing alpha-linked alpha-D-glucose residue with release of alpha-D-glucose.
Synonyms:xref: EC:3.2.1.20;   Reactome:R-HSA-9036729 "Defective GAA does not hydrolyze lysosomal glycogen";   reactome:R-HSA-9036727 "GAA hydrolyzes lysosomal glycogen"


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alpha-glucosidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GAA alpha glucosidase enables EXP
TAS
IEA		 (PMID:5264799) Reactome
UniProt		 PMID:5264799 GO_REF:0000117 Reactome:R-HSA-9036729 NCBI chr17:80,101,581...80,119,881
Ensembl chr17:80,101,533...80,119,881 		JBrowse link
G GANAB glucosidase II alpha subunit enables IDA
IEA		 (PMID:28375157) UniProt PMID:28375157 GO_REF:0000117 NCBI chr11:62,624,829...62,646,613
Ensembl chr11:62,624,826...62,646,726 		JBrowse link
G GANC glucosidase alpha, neutral C enables IEA UniProt GO_REF:0000117 NCBI chr15:42,273,201...42,353,666
Ensembl chr15:42,273,201...42,353,666 		JBrowse link
G MGAM maltase-glucoamylase enables IEA UniProt GO_REF:0000117 NCBI chr 7:141,986,518...142,106,747
Ensembl chr 7:141,907,813...142,106,747 		JBrowse link
G MGAM2 maltase-glucoamylase 2 (putative) enables IEA UniProt GO_REF:0000117 NCBI chr 7:142,111,718...142,222,324
Ensembl chr 7:142,111,718...142,222,324 		JBrowse link
G SI sucrase-isomaltase enables IEA UniProt GO_REF:0000117 NCBI chr 3:164,978,898...165,157,921
Ensembl chr 3:164,978,898...165,078,496 		JBrowse link
alpha-1,4-glucosidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GAA alpha glucosidase enables ISO
IBA
IEA
IDA		 (PMID:29061980), (PMID:9505277) RGD
GO_Central
Ensembl
UniProt		 PMID:2193931 PMID:8702598 PMID:8710802 PMID:9505277 PMID:29061980 GO_REF:0000033 GO_REF:0000107 RGD:1599504 RGD:1599506 RGD:1625498 NCBI chr17:80,101,581...80,119,881
Ensembl chr17:80,101,533...80,119,881 		JBrowse link
G GANC glucosidase alpha, neutral C enables NAS
IEA
IBA		 (PMID:12370436) UniProt
TreeGrafter
GO_Central		 PMID:12370436 GO_REF:0000033 GO_REF:0000118 NCBI chr15:42,273,201...42,353,666
Ensembl chr15:42,273,201...42,353,666 		JBrowse link
G MGAM maltase-glucoamylase enables IDA
IBA
IEA		 (PMID:18036614), (PMID:22058037), (PMID:27480812) UniProt
GO_Central
TreeGrafter
Ensembl		 PMID:18036614 PMID:22058037 PMID:27480812 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:141,986,518...142,106,747
Ensembl chr 7:141,907,813...142,106,747 		JBrowse link
G MGAM2 maltase-glucoamylase 2 (putative) enables IBA GO_Central GO_REF:0000033 NCBI chr 7:142,111,718...142,222,324
Ensembl chr 7:142,111,718...142,222,324 		JBrowse link
G SI sucrase-isomaltase enables IBA GO_Central GO_REF:0000033 NCBI chr 3:164,978,898...165,157,921
Ensembl chr 3:164,978,898...165,078,496 		JBrowse link
amylo-alpha-1,6-glucosidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase enables ISO
IEA
EXP
IBA		 (PMID:2961257) RGD
InterPro
Reactome
UniProt
Ensembl
GO_Central
TreeGrafter		 PMID:2961257 PMID:6449198 PMID:15180797 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 RGD:1642741 RGD:1642743 NCBI chr 1:99,849,258...99,924,023
Ensembl chr 1:99,850,361...99,924,023 		JBrowse link
glucan 1,3-alpha-glucosidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GANAB glucosidase II alpha subunit enables IDA
IEA
IBA		 (PMID:10929008) UniProt
TreeGrafter
GO_Central
Ensembl		 PMID:10929008 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr11:62,624,829...62,646,613
Ensembl chr11:62,624,826...62,646,726 		JBrowse link
maltose alpha-glucosidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GAA alpha glucosidase enables IEA UniProt GO_REF:0000003 NCBI chr17:80,101,581...80,119,881
Ensembl chr17:80,101,533...80,119,881 		JBrowse link
G GANC glucosidase alpha, neutral C enables IEA UniProt GO_REF:0000003 NCBI chr15:42,273,201...42,353,666
Ensembl chr15:42,273,201...42,353,666 		JBrowse link
G MGAM maltase-glucoamylase enables IEA UniProt GO_REF:0000003 NCBI chr 7:141,986,518...142,106,747
Ensembl chr 7:141,907,813...142,106,747 		JBrowse link
G SLC3A1 solute carrier family 3 member 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 2:44,275,480...44,322,437
Ensembl chr 2:44,275,458...44,321,494 		JBrowse link
oligo-1,6-glucosidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SI sucrase-isomaltase enables ISO
IDA
IEA		 (PMID:27480812) RGD
UniProt		 PMID:6802834 PMID:27480812 GO_REF:0000003 RGD:1625556 NCBI chr 3:164,978,898...165,157,921
Ensembl chr 3:164,978,898...165,078,496 		JBrowse link
G SLC3A1 solute carrier family 3 member 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 2:44,275,480...44,322,437
Ensembl chr 2:44,275,458...44,321,494 		JBrowse link
sucrose alpha-glucosidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SI sucrase-isomaltase enables IEA
TAS		 UniProt
Reactome		 GO_REF:0000003 Reactome:R-HSA-189069 NCBI chr 3:164,978,898...165,157,921
Ensembl chr 3:164,978,898...165,078,496 		JBrowse link
G SLC3A1 solute carrier family 3 member 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 2:44,275,480...44,322,437
Ensembl chr 2:44,275,458...44,321,494 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19489
    catalytic activity 5987
      hydrolase activity 2610
        hydrolase activity, acting on glycosyl bonds 151
          hydrolase activity, hydrolyzing O-glycosyl compounds 108
            glucosidase activity 16
              alpha-glucosidase activity 8
                alpha-1,3-glucosidase activity + 1
                alpha-1,4-glucosidase activity + 6
                amylo-alpha-1,6-glucosidase activity 1
                dextrin alpha-glucosidase activity 0
                maltose glucosidase activity 0
                oligo-1,6-glucosidase activity 2
                starch alpha-glucosidase activity 0
                sucrose alpha-glucosidase activity 2
paths to the root