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ONTOLOGY REPORT - ANNOTATIONS

Term:IPAF inflammasome complex
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Accession:GO:0072557 term browser browse the term
Definition:An inflammasome complex that consists of three components, IPAF, NAIP and caspase-1, and includes among its functions the sensing of flagellin derived from Legionella pneumophila, Salmonella typhimurium, Pseudomonas aeruginosa and Shigella flexneri.


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IPAF inflammasome complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp1 caspase 1 part_of IEA
ISS
IBA
ISO		 GO_REF:0000107
GO_REF:0000024
GO_REF:0000033
(PMID:21874021)		 Ensembl
UniProt
GO_Central
RGD		 PMID:21874021 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp4 caspase 4 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Naip5 NLR family, apoptosis inhibitory protein 5 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:31,557,706...31,608,722
Ensembl chr 2:31,557,817...31,608,634 		JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 part_of IBA
ISO		 GO_REF:0000033
(PMID:21874021)		 GO_Central
RGD		 PMID:21874021 GO_REF:0000033 NCBI chr 2:31,507,423...31,559,098
Ensembl chr 2:31,507,424...31,570,542 		JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 part_of ISS
ISO		 GO_REF:0000024
(PMID:21874021), (PMID:22885697)		 UniProt
RGD		 PMID:21874021 PMID:22885697 GO_REF:0000024 NCBI chr 6:20,991,785...21,018,254
Ensembl chr 6:20,995,266...21,018,248 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21321
    protein-containing complex 6790
      canonical inflammasome complex 28
        IPAF inflammasome complex 5
Path 2
Term Annotations click to browse term
  cellular_component 21321
    cellular anatomical structure 21026
      intracellular anatomical structure 15547
        cytoplasm 12254
          cytosol 4507
            canonical inflammasome complex 28
              IPAF inflammasome complex 5
paths to the root