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ONTOLOGY REPORT - ANNOTATIONS

Term:canonical inflammasome complex
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Accession:GO:0061702 term browser browse the term
Definition:A cytosolic protein complex that is capable of activating caspase-1.


show annotations for term's descendants           Sort by:
canonical inflammasome complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp1 caspase 1 part_of ISO (PMID:16037825) RGD PMID:16037825 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Mefv MEFV innate immunity regulator, pyrin part_of ISO (PMID:16037825) RGD PMID:16037825 NCBI chr10:11,786,948...11,796,977
Ensembl chr10:11,787,422...11,796,973 		JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 part_of IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr10:11,551,378...11,585,027
Ensembl chr10:11,551,356...11,584,398 		JBrowse link
G Nlrp10 NLR family, pyrin domain containing 10 part_of IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 1:162,922,806...162,930,363
Ensembl chr 1:162,922,806...162,930,363 		JBrowse link
G Nlrp12 NLR family, pyrin domain containing 12 part_of IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 1:65,932,610...65,969,873
Ensembl chr 1:65,932,595...65,960,934 		JBrowse link
G Nlrp14 NLR family, pyrin domain containing 14 part_of IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 1:161,069,141...161,089,158
Ensembl chr 1:161,061,165...161,089,222 		JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A part_of IEA
IBA
ISO		 GO_REF:0000044
GO_REF:0000033
(PMID:33731929)		 UniProt
GO_Central
RGD		 PMID:33731929 GO_REF:0000033 GO_REF:0000044 NCBI chr10:55,778,560...55,833,639
Ensembl chr10:55,778,560...55,825,180 		JBrowse link
G Nlrp1b NLR family, pyrin domain containing 1B part_of IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr10:55,838,381...55,904,374
Ensembl chr10:55,843,001...55,912,774 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 part_of ISO
IEA		 (PMID:30248149)
GO_REF:0000044		 RGD
UniProt		 PMID:30248149 GO_REF:0000044 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nlrp4 NLR family, pyrin domain containing 4 part_of IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 1:68,089,321...68,132,429
Ensembl chr 1:68,089,321...68,127,521 		JBrowse link
G Nlrp4a NLR family, pyrin domain containing 4A part_of IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 1:66,171,037...66,258,045
Ensembl chr 1:66,170,592...66,245,316 		JBrowse link
G Nlrp4al1 NLR family, pyrin domain containing 4A like 1 part_of IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 7:13,464,475...13,489,185
Ensembl chr 7:13,464,255...13,489,185 		JBrowse link
G Nlrp4b NLR family, pyrin domain containing 4B part_of IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 1:70,426,021...70,457,919
Ensembl chr 1:70,426,161...70,457,919 		JBrowse link
G Nlrp4f NLR family, pyrin domain containing 4F part_of IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 1:66,273,079...66,294,331
Ensembl chr 1:66,277,456...66,294,331 		JBrowse link
G Nlrp5 NLR family, pyrin domain containing 5 part_of IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 1:67,778,037...67,810,941
Ensembl chr 1:67,777,948...68,023,736 		JBrowse link
G Nlrp6 NLR family, pyrin domain containing 6 part_of IEA
ISO
IBA		 GO_REF:0000044
(PMID:30248149)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:30248149 GO_REF:0000033 GO_REF:0000044 NCBI chr 1:196,004,854...196,011,615
Ensembl chr 1:196,004,953...196,011,113 		JBrowse link
G Nlrp9 NLR family, pyrin domain containing 9 part_of ISO
IBA		 (PMID:28636595)
GO_REF:0000033		 RGD
GO_Central		 PMID:28636595 GO_REF:0000033 NCBI chr 1:68,291,180...68,341,512
Ensembl chr 1:68,291,180...68,341,512 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 part_of IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 part_of IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Pycard PYD and CARD domain containing part_of IBA
ISO		 GO_REF:0000033
(PMID:16037825)
(PMID:30248149)		 GO_Central
RGD		 PMID:16037825 PMID:30248149 GO_REF:0000033 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
AIM2 inflammasome complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aim2 absent in melanoma 2 part_of IBA
ISO		 GO_REF:0000033
(PMID:19158676), (PMID:19158679), (PMID:24630722), (PMID:26197926), (PMID:29440442), (PMID:33980849)
(MGI:5807418|PMID:27846608), (PMID:19158679)		 GO_Central
RGD		 PMID:19158676 PMID:19158679 PMID:24630722 PMID:26197926 PMID:27846608 More... GO_REF:0000033 MGI:5807418 NCBI chr13:85,865,206...85,906,996
Ensembl chr13:85,866,284...85,906,975 		JBrowse link
G Casp1 caspase 1 part_of ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:19158676), (PMID:24630722)		 UniProt
GO_Central
RGD		 PMID:19158676 PMID:24630722 GO_REF:0000024 GO_REF:0000033 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Pycard PYD and CARD domain containing part_of ISO (PMID:19158676), (PMID:24630722) RGD PMID:19158676 PMID:24630722 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
IPAF inflammasome complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp1 caspase 1 part_of IEA
IBA
ISO
ISS		 GO_REF:0000107
GO_REF:0000033
(MGI:5289703|PMID:21874021)
GO_REF:0000024		 Ensembl
GO_Central
RGD
UniProt		 PMID:21874021 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:5289703 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 part_of ISO
IBA		 (MGI:5289703|PMID:21874021)
GO_REF:0000033		 RGD
GO_Central		 PMID:21874021 GO_REF:0000033 MGI:5289703 NCBI chr 2:31,507,423...31,559,098
Ensembl chr 2:31,507,424...31,570,542 		JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 part_of ISS
ISO		 GO_REF:0000024
(MGI:5289703|PMID:21874021), (MGI:5444805|PMID:22885697)		 UniProt
RGD		 PMID:21874021 PMID:22885697 GO_REF:0000024 MGI:5289703 MGI:5444805 NCBI chr 6:20,991,785...21,018,254
Ensembl chr 6:20,995,266...21,018,248 		JBrowse link
NLRP1 inflammasome complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp1 caspase 1 part_of ISS
ISO		 GO_REF:0000024
(PMID:12191486), (PMID:17349957)		 UniProt
RGD		 PMID:12191486 PMID:17349957 GO_REF:0000024 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp12 caspase 12 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037 		JBrowse link
G Casp4 caspase 4 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A part_of ISS
ISO		 GO_REF:0000024
(PMID:12191486), (PMID:17349957), (PMID:30291141), (PMID:33420028), (PMID:33420033)		 UniProt
RGD		 PMID:12191486 PMID:17349957 PMID:30291141 PMID:33420028 PMID:33420033 GO_REF:0000024 NCBI chr10:55,778,560...55,833,639
Ensembl chr10:55,778,560...55,825,180 		JBrowse link
G Pycard PYD and CARD domain containing part_of ISO (PMID:12191486), (PMID:17349957) RGD PMID:12191486 PMID:17349957 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
NLRP3 inflammasome complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp1 caspase 1 part_of ISS
ISO
IBA		 GO_REF:0000024
(PMID:15030775), (PMID:29255148)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:15030775 PMID:29255148 GO_REF:0000024 GO_REF:0000033 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked part_of ISO (MGI:6368386|PMID:31511697) RGD PMID:31511697 MGI:6368386 NCBI chr  X:9,479,532...9,493,169
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Dhx33 DEAH-box helicase 33 part_of ISO (PMID:23871209) RGD PMID:23871209 NCBI chr10:55,708,102...55,724,618
Ensembl chr10:55,705,756...55,724,567 		JBrowse link
G Gsdmd gasdermin D part_of ISO
IBA		 (MGI:5751630|PMID:26611636)
GO_REF:0000033		 RGD
GO_Central		 PMID:26611636 GO_REF:0000033 MGI:5751630 NCBI chr 7:107,542,489...107,547,051
Ensembl chr 7:107,542,083...107,547,055 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 part_of ISO
IBA		 (MGI:5790524|PMID:27374331)
(PMID:15030775), (PMID:29255148), (PMID:36442502)
GO_REF:0000033		 RGD
GO_Central		 PMID:15030775 PMID:27374331 PMID:29255148 PMID:36442502 GO_REF:0000033 MGI:5790524 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Pycard PYD and CARD domain containing part_of ISO (PMID:15030775), (PMID:29255148) RGD PMID:15030775 PMID:29255148 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
NLRP6 inflammasome complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nlrp6 NLR family, pyrin domain containing 6 part_of ISO
ISS
IEA		 (PMID:30674671), (PMID:31932628), (PMID:34678144)
GO_REF:0000024
(MGI:6706628|PMID:32424362), (MGI:6833928|PMID:34678144)
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:30674671 PMID:31932628 PMID:32424362 PMID:34678144 GO_REF:0000024 GO_REF:0000107 MGI:6706628 MGI:6833928 NCBI chr 1:196,004,854...196,011,615
Ensembl chr 1:196,004,953...196,011,113 		JBrowse link
G Pycard PYD and CARD domain containing part_of ISO (PMID:30674671), (PMID:34678144)
(MGI:6833928|PMID:34678144)		 RGD PMID:30674671 PMID:34678144 MGI:6833928 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20811
    protein-containing complex 6431
      canonical inflammasome complex 28
        AIM2 inflammasome complex 3
        CARD8 inflammasome complex 0
        IPAF inflammasome complex 3
        NLRP1 inflammasome complex 5
        NLRP3 inflammasome complex 6
        NLRP6 inflammasome complex 2
Path 2
Term Annotations click to browse term
  cellular_component 20811
    cellular anatomical entity 20571
      intracellular anatomical structure 15179
        cytoplasm 11872
          cytosol 4228
            canonical inflammasome complex 28
              AIM2 inflammasome complex 3
              CARD8 inflammasome complex 0
              IPAF inflammasome complex 3
              NLRP1 inflammasome complex 5
              NLRP3 inflammasome complex 6
              NLRP6 inflammasome complex 2
paths to the root