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ONTOLOGY REPORT - ANNOTATIONS


Term:inflammasome complex
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Accession:GO:0061702 term browser browse the term
Definition:A cytosolic protein complex that is capable of activating caspase-1.


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inflammasome complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nlrp1a NLR family, pyrin domain containing 1A part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:57,692,474...57,747,608
Ensembl chr10:57,692,474...57,822,498
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 part_of ISO (MGI:6453663|PMID:30248149) RGD PMID:30248149 MGI:6453663 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Nlrp6 NLR family, pyrin domain containing 6 part_of IEA
ISO
GO_REF:0000044
(MGI:6453663|PMID:30248149)
UniProt
RGD
PMID:30248149 GO_REF:0000044 MGI:6453663 NCBI chr 1:213,676,954...213,683,114
Ensembl chr 1:213,686,046...213,691,943
JBrowse link
G Nlrp9 NLR family, pyrin domain containing 9 part_of ISO (PMID:28636595) RGD PMID:28636595 NCBI chr 1:71,859,390...71,917,337
Ensembl chr 1:71,859,390...71,909,138
JBrowse link
G Pycard PYD and CARD domain containing part_of ISO (MGI:6453663|PMID:30248149) RGD PMID:30248149 MGI:6453663 NCBI chr 1:199,438,029...199,439,062
Ensembl chr 1:199,437,832...199,439,210
JBrowse link
AIM2 inflammasome complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aim2 absent in melanoma 2 part_of ISO
IBA
(PMID:19158676), (PMID:19158679)
PMID:21873635
(MGI:3836373|PMID:19158679)
RGD PMID:19158676 PMID:19158679, PMID:21873635 MGI:3836373, RGD:13792537 NCBI chr13:91,919,834...91,963,080
Ensembl chr13:91,954,138...91,962,588
JBrowse link
G Casp1 caspase 1 part_of ISS
IEA
ISO
IBA
GO_REF:0000024
GO_REF:0000107
(PMID:19158676)
PMID:21873635
UniProt
Ensembl
RGD
PMID:19158676, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp12 caspase 12 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp4 caspase 4 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
JBrowse link
G Pycard PYD and CARD domain containing part_of ISO (PMID:19158676) RGD PMID:19158676 NCBI chr 1:199,438,029...199,439,062
Ensembl chr 1:199,437,832...199,439,210
JBrowse link
IPAF inflammasome complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC135826.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 2:30,376,419...30,458,542 JBrowse link
G Casp1 caspase 1 part_of IEA
ISO
ISS
IBA
GO_REF:0000107
(MGI:5289703|PMID:21874021)
GO_REF:0000024
PMID:21873635
Ensembl
RGD
UniProt
PMID:21874021, PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5289703, RGD:13792537 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp12 caspase 12 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp4 caspase 4 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 part_of ISO (MGI:5289703|PMID:21874021) RGD PMID:21874021 MGI:5289703 NCBI chr 2:30,377,505...30,418,578 JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 part_of ISS
ISO
GO_REF:0000024
(MGI:5289703|PMID:21874021), (MGI:5444805|PMID:22885697)
UniProt
RGD
PMID:21874021 PMID:22885697 GO_REF:0000024 MGI:5289703 MGI:5444805 NCBI chr 6:22,167,874...22,194,755
Ensembl chr 6:22,167,919...22,194,250
JBrowse link
NLRP1 inflammasome complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp1 caspase 1 part_of ISS
ISO
IEA
GO_REF:0000024
(PMID:12191486)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:12191486 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A part_of ISO (PMID:12191486) RGD PMID:12191486 NCBI chr10:57,692,474...57,747,608
Ensembl chr10:57,692,474...57,822,498
JBrowse link
G Pycard PYD and CARD domain containing part_of ISO (PMID:12191486) RGD PMID:12191486 NCBI chr 1:199,438,029...199,439,062
Ensembl chr 1:199,437,832...199,439,210
JBrowse link
NLRP3 inflammasome complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp1 caspase 1 part_of IEA
IBA
ISS
ISO
GO_REF:0000107
PMID:21873635
GO_REF:0000024
(PMID:15030775)
Ensembl
UniProt
RGD
PMID:15030775, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp12 caspase 12 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp4 caspase 4 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked part_of ISO (MGI:6368386|PMID:31511697) RGD PMID:31511697 MGI:6368386 NCBI chr  X:10,400,363...10,414,010
Ensembl chr  X:10,400,366...10,413,995
JBrowse link
G Dhx33 DEAH-box helicase 33 part_of ISO (PMID:23871209) RGD PMID:23871209 NCBI chr10:57,622,022...57,638,485
Ensembl chr10:57,622,022...57,638,485
JBrowse link
G Gsdmd gasdermin D part_of IBA
ISO
PMID:21873635
(MGI:5751630|PMID:26611636)
RGD PMID:26611636, PMID:21873635 MGI:5751630, RGD:13792537 NCBI chr 7:116,889,147...116,894,134
Ensembl chr 7:116,889,572...116,894,134
JBrowse link
G Nlrp1b NLR family, pyrin domain containing 1B part_of ISO (PMID:15030775) RGD PMID:15030775 NCBI chr10:57,755,957...57,847,867 JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 part_of ISO (PMID:15030775)
(MGI:5790524|PMID:27374331)
RGD PMID:15030775 PMID:27374331 MGI:5790524 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Pycard PYD and CARD domain containing part_of ISO (PMID:15030775) RGD PMID:15030775 NCBI chr 1:199,438,029...199,439,062
Ensembl chr 1:199,437,832...199,439,210
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20142
    protein-containing complex 6031
      inflammasome complex 16
        AIM2 inflammasome complex 5
        CARD8 inflammasome complex 0
        IPAF inflammasome complex 6
        NLRP1 inflammasome complex 3
        NLRP3 inflammasome complex 9
Path 2
Term Annotations click to browse term
  cellular_component 20142
    cellular anatomical entity 19842
      intracellular anatomical structure 14431
        cytoplasm 11417
          cytosol 4243
            inflammasome complex 16
              AIM2 inflammasome complex 5
              CARD8 inflammasome complex 0
              IPAF inflammasome complex 6
              NLRP1 inflammasome complex 3
              NLRP3 inflammasome complex 9
paths to the root