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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:interleukin-27-mediated signaling pathway
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Accession:GO:0070106 term browser browse the term
Definition:The series of molecular signals initiated by interleukin-27 binding to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: IL-27-mediated signaling pathway;   IL27RA/IL6ST signaling pathway;   interleukin-27-mediated signalling pathway


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interleukin-27-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL27RA interleukin 27 receptor subunit alpha involved_in IEA GOC GO_REF:0000108 NCBI chr20:48,456,766...48,475,414
Ensembl chr20:48,457,134...48,472,450 		JBrowse link
G IL6ST interleukin 6 cytokine family signal transducer involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:43,214,050...43,273,014
Ensembl chr 2:43,214,050...43,248,124 		JBrowse link
G LOC477518 oligoadenylate synthetase-like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:16,855,386...16,869,102
Ensembl chr26:16,855,386...16,869,102 		JBrowse link
G MX1 MX dynamin like GTPase 1 involved_in ISO (PMID:32270034) ARUK-UCL PMID:32270034 NCBI chr31:35,898,206...35,929,802
Ensembl chr31:35,860,590...35,951,350 		JBrowse link
G OAS1 2'-5'-oligoadenylate synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:10,385,393...10,396,734
Ensembl chr26:10,385,447...10,396,733 		JBrowse link
G OAS2 2'-5'-oligoadenylate synthetase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:10,431,881...10,450,085
Ensembl chr26:10,432,042...10,449,009 		JBrowse link
G OASL 2'-5'-oligoadenylate synthetase like involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:16,837,376...16,850,388
Ensembl chr26:16,837,376...16,850,388 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:1,513,438...1,549,837
Ensembl chr37:1,507,219...1,550,178 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17925
    cellular process 16910
      signal transduction 6317
        cell surface receptor signaling pathway 2807
          cytokine-mediated signaling pathway 493
            interleukin-27-mediated signaling pathway 8
              negative regulation of interleukin-27-mediated signaling pathway 0
              positive regulation of interleukin-27-mediated signaling pathway 0
              regulation of interleukin-27-mediated signaling pathway + 0
Path 2
Term Annotations click to browse term
  biological_process 17925
    biological regulation 12446
      regulation of biological process 12082
        regulation of cellular process 11572
          signal transduction 6317
            cell surface receptor signaling pathway 2807
              cytokine-mediated signaling pathway 493
                interleukin-27-mediated signaling pathway 8
                  negative regulation of interleukin-27-mediated signaling pathway 0
                  positive regulation of interleukin-27-mediated signaling pathway 0
                  regulation of interleukin-27-mediated signaling pathway + 0
paths to the root