canonical Wnt signaling pathway involved in heart development - Ontology Report

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Term:	canonical Wnt signaling pathway involved in heart development	go back to main search page
Accession:	GO:0061316	browse the term
Definition:	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the heart over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
Synonyms:	exact_synonym:	canonical Wnt receptor signaling pathway involved in heart development; canonical Wnt receptor signalling pathway involved in heart development; canonical Wnt-activated signaling pathway involved in heart development

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Term paths to the root

Path 1
Term	Annotations
biological_process	20076
cellular process	19155
signal transduction	7183
cell surface receptor signaling pathway	2842
cell surface receptor signaling pathway involved in heart development	6
Wnt signaling pathway involved in heart development	1
canonical Wnt signaling pathway involved in heart development	0
Path 2
Term	Annotations
biological_process	20076
developmental process	7070
anatomical structure development	6573
multicellular organism development	5299
system development	4584
circulatory system development	1374
heart development	745
cell surface receptor signaling pathway involved in heart development	6
Wnt signaling pathway involved in heart development	1
canonical Wnt signaling pathway involved in heart development	0

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