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ONTOLOGY REPORT - ANNOTATIONS

Term:response to cortisol
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Accession:GO:0051414 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions.
Synonyms:exact_synonym: response to cortisol stimulus;   response to hydrocortisone stimulus


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response to cortisol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase involved_in ISO
IEA		 RGD
Ensembl		 PMID:2353918 GO_REF:0000107 RGD:2303529 NCBI chr 2:27,217,369...27,243,943
Ensembl chr 2:27,217,369...27,243,943 		JBrowse link
G IGFBP7 insulin like growth factor binding protein 7 involved_in ISO
IEA		 RGD
Ensembl		 PMID:9886829 GO_REF:0000107 RGD:1626580 NCBI chr 4:57,030,773...57,110,385
Ensembl chr 4:57,030,773...57,110,385 		JBrowse link
G SLIT2 slit guidance ligand 2 involved_in IEP (PMID:18566128) UniProt PMID:18566128 NCBI chr 4:20,251,905...20,620,561
Ensembl chr 4:20,251,905...20,620,561 		JBrowse link
G SLIT3 slit guidance ligand 3 involved_in IEP (PMID:18566128) UniProt PMID:18566128 NCBI chr 5:168,661,740...169,301,139
Ensembl chr 5:168,661,740...169,301,139 		JBrowse link
G TK1 thymidine kinase 1 ISO RGD PMID:7208144 RGD:2317233 NCBI chr17:78,174,079...78,187,204
Ensembl chr17:78,174,091...78,187,233 		JBrowse link
cellular response to cortisol stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:8674863 GO_REF:0000107 RGD:7829730 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G KLF9 KLF transcription factor 9 involved_in IDA (PMID:22711835) UniProt PMID:22711835 NCBI chr 9:70,384,604...70,414,657
Ensembl chr 9:70,384,604...70,414,657 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19613
    response to stimulus 10170
      response to chemical 5025
        response to oxygen-containing compound 2479
          response to alcohol 550
            response to cortisol 7
              cellular response to cortisol stimulus 2
Path 2
Term Annotations click to browse term
  biological_process 19613
    response to stimulus 10170
      response to endogenous stimulus 2314
        response to hormone 1345
          response to steroid hormone 567
            response to corticosteroid 353
              response to glucocorticoid 314
                response to cortisol 7
                  cellular response to cortisol stimulus 2
paths to the root