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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:Tie signaling pathway
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Accession:GO:0048014 term browser browse the term
Definition:The series of molecular signals initiated by an angiopoietin binding to the Tie receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: Tek receptor signaling;   Tie receptor signaling pathway;   Tie receptor signalling pathway
 narrow_synonym: angiopoietin-Tie signaling pathway


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Tie signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANGPT1 angiopoietin 1 involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr13:8,068,920...8,312,090
Ensembl chr13:8,048,205...8,311,618 		JBrowse link
G ANGPT2 angiopoietin 2 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr16:58,404,049...58,458,344
Ensembl chr16:58,405,259...58,457,701 		JBrowse link
G SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28179430) Ensembl
MGI		 PMID:28179430 GO_REF:0000107 NCBI chr11:65,312,723...65,494,014
Ensembl chr11:65,289,087...65,637,974 		JBrowse link
G TEK TEK receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:45,278,375...45,377,300
Ensembl chr11:45,278,891...45,409,093 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17925
    cellular process 16910
      signal transduction 6317
        cell surface receptor signaling pathway 2807
          enzyme-linked receptor protein signaling pathway 1041
            cell surface receptor protein tyrosine kinase signaling pathway 654
              Tie signaling pathway 4
Path 2
Term Annotations click to browse term
  biological_process 17925
    biological regulation 12446
      regulation of biological process 12082
        signaling 6866
          signal transduction 6317
            cell surface receptor signaling pathway 2807
              enzyme-linked receptor protein signaling pathway 1041
                cell surface receptor protein tyrosine kinase signaling pathway 654
                  Tie signaling pathway 4
paths to the root