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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of osteoblast differentiation
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Accession:GO:0045669 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of osteoblast differentiation.
Synonyms:exact_synonym: up regulation of osteoblast differentiation;   upregulation of osteoblast differentiation
 narrow_synonym: activation of osteoblast differentiation;   stimulation of osteoblast differentiation

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positive regulation of osteoblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624732:7,929,997...8,004,235
Ensembl chrNW_004624732:7,929,583...8,005,072 		JBrowse link
G Acvr2a activin A receptor type 2A involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004624866:539,967...619,575
Ensembl chrNW_004624866:539,894...620,302 		JBrowse link
G Acvr2b activin A receptor type 2B involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004624731:2,557,993...2,600,250
Ensembl chrNW_004624731:2,566,063...2,600,035 		JBrowse link
G Atraid all-trans retinoic acid induced differentiation factor involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624738:9,311,746...9,318,099
Ensembl chrNW_004624738:9,311,836...9,317,861 		JBrowse link
G Bmp2 bone morphogenetic protein 2 acts_upstream_of_or_within
involved_in		 ISO (PMID:15175325), (PMID:16099986)
(PMID:20675382)		 MGI
BHF-UCL		 PMID:15175325 PMID:16099986 PMID:20675382 NCBI chrNW_004624741:7,706,205...7,717,677
Ensembl chrNW_004624741:7,706,236...7,719,484 		JBrowse link
G Bmp4 bone morphogenetic protein 4 acts_upstream_of_or_within
involved_in		 ISO (PMID:14749725)
(PMID:18436533)		 RGD
MGI
BHF-UCL		 PMID:14749725 PMID:16245174 PMID:17112416 PMID:18436533 RGD:1643600 RGD:2289011 NCBI chrNW_004624731:15,262,480...15,269,196
Ensembl chrNW_004624731:15,263,274...15,269,743 		JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in ISO (PMID:18436533) BHF-UCL
RGD		 PMID:9202223 PMID:18436533 RGD:2289027 NCBI chrNW_004624756:17,742,822...17,894,931
Ensembl chrNW_004624756:17,743,834...17,894,753 		JBrowse link
G Bmp7 bone morphogenetic protein 7 involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004624741:23,658,214...23,743,227
Ensembl chrNW_004624741:23,658,004...23,737,742 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004624841:218,642...304,744
Ensembl chrNW_004624841:219,133...265,397 		JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004624757:22,697,639...23,142,209
Ensembl chrNW_004624757:22,955,666...23,142,499 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004624765:13,849,689...13,950,839
Ensembl chrNW_004624765:13,857,062...13,947,683 		JBrowse link
G Ccn1 cellular communication network factor 1 involved_in ISO (PMID:20675382) BHF-UCL PMID:20675382 NCBI chrNW_004624742:11,882,815...11,885,686
Ensembl chrNW_004624742:11,882,907...11,885,667 		JBrowse link
G Ccn4 cellular communication network factor 4 involved_in ISO (PMID:20684029) UniProt PMID:20684029 NCBI chrNW_004624735:22,789,784...22,819,527
Ensembl chrNW_004624735:22,788,475...22,819,648 		JBrowse link
G Cd276 CD276 molecule acts_upstream_of_or_within ISO (PMID:15317945) MGI PMID:15317945 NCBI chrNW_004624781:691,348...703,202 JBrowse link
G Cebpa CCAAT enhancer binding protein alpha acts_upstream_of_or_within ISO (PMID:15175325) MGI PMID:15175325 NCBI chrNW_004624794:9,809,007...9,813,418 JBrowse link
G Cebpb CCAAT enhancer binding protein beta acts_upstream_of_or_within ISO (PMID:15175325) MGI PMID:15175325 NCBI chrNW_004624790:5,367,808...5,369,686
Ensembl chrNW_004624790:5,368,349...5,369,377 		JBrowse link
G Cebpd CCAAT enhancer binding protein delta acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15175325) MGI
Ensembl		 PMID:15175325 GO_REF:0000107 NCBI chrNW_004624735:7,721,564...7,722,823
Ensembl chrNW_004624735:7,721,633...7,722,445 		JBrowse link
G Clic1 chloride intracellular channel 1 acts_upstream_of_or_within ISO (PMID:19703605) MGI PMID:19703605 NCBI chrNW_004624754:24,476,262...24,482,529
Ensembl chrNW_004624754:24,476,213...24,482,529 		JBrowse link
G Cthrc1 collagen triple helix repeat containing 1 acts_upstream_of_or_within ISO (PMID:18779865) MGI PMID:18779865 NCBI chrNW_004624763:19,917,199...19,925,824
Ensembl chrNW_004624763:19,917,169...19,925,896 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15866163) Ensembl
MGI		 PMID:15866163 GO_REF:0000107 NCBI chrNW_004624730:77,876,361...77,887,228
Ensembl chrNW_004624730:77,875,257...77,887,234 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 involved_in ISO (PMID:20564243) UniProt PMID:20564243 NCBI chrNW_004624826:1,225,217...1,255,889
Ensembl chrNW_004624826:1,173,621...1,249,692 		JBrowse link
G Dlx5 distal-less homeobox 5 ISO RGD PMID:12815054 RGD:1298882 NCBI chrNW_004624813:3,760,890...3,765,309
Ensembl chrNW_004624813:3,760,661...3,765,517 		JBrowse link
G Dnai3 dynein axonemal intermediate chain 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624742:12,369,903...12,463,184
Ensembl chrNW_004624742:12,369,834...12,463,215 		JBrowse link
G Fam20c FAM20C golgi associated secretory pathway kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22615579) Ensembl
MGI		 PMID:22615579 GO_REF:0000107 NCBI chrNW_004624740:25,984,642...26,032,089
Ensembl chrNW_004624740:25,984,091...26,032,649 		JBrowse link
G Fbn2 fibrillin 2 involved_in ISO (PMID:20855508) BHF-UCL PMID:20855508 NCBI chrNW_004624774:12,863,446...13,116,929
Ensembl chrNW_004624774:12,863,446...13,116,545 		JBrowse link
G Fbxo5 F-box protein 5 involved_in ISO (PMID:29850565) UniProt PMID:29850565 NCBI chrNW_004624785:5,248,434...5,260,623
Ensembl chrNW_004624785:5,247,731...5,260,736 		JBrowse link
G Fermt2 FERM domain containing kindlin 2 involved_in ISO (PMID:29496737) ARUK-UCL PMID:29496737 NCBI chrNW_004624731:16,168,179...16,247,747
Ensembl chrNW_004624731:16,168,207...16,246,778 		JBrowse link
G Ffar4 free fatty acid receptor 4 involved_in ISO (PMID:26365922) UniProt PMID:26365922 NCBI chrNW_004624737:4,770,328...4,795,150
Ensembl chrNW_004624737:4,770,564...4,792,585 		JBrowse link
G Fgf2 fibroblast growth factor 2 acts_upstream_of_or_within ISO (PMID:20570969) MGI PMID:20570969 NCBI chrNW_004624777:3,268,674...3,321,424
Ensembl chrNW_004624777:3,268,953...3,321,145 		JBrowse link
G Fzd1 frizzled class receptor 1 involved_in ISO (PMID:20039315) BHF-UCL PMID:20039315 NCBI chrNW_004624809:2,021,118...2,025,826
Ensembl chrNW_004624809:2,021,124...2,025,589 		JBrowse link
G Gdpd2 glycerophosphodiester phosphodiesterase domain containing 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12933806) Ensembl
MGI		 PMID:12933806 GO_REF:0000107 NCBI chrNW_004624903:388,935...399,793
Ensembl chrNW_004624903:388,866...400,607 		JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO (PMID:20570969) MGI PMID:20570969 NCBI chrNW_004624740:18,961,395...19,238,760
Ensembl chrNW_004624740:18,975,596...19,235,900 		JBrowse link
G Gnas GNAS complex locus acts_upstream_of_or_within ISO (PMID:15797856) MGI PMID:15797856 NCBI chrNW_004624741:25,138,678...25,197,194
Ensembl chrNW_004624741:25,183,329...25,196,880 		JBrowse link
G Hey1 hes related family bHLH transcription factor with YRPW motif 1 acts_upstream_of_or_within ISO (PMID:18986983) MGI PMID:18986983 NCBI chrNW_004624744:11,462,865...11,466,559
Ensembl chrNW_004624744:11,462,847...11,467,870 		JBrowse link
G Igf1 insulin like growth factor 1 involved_in ISO (PMID:16433617) BHF-UCL
RGD		 PMID:16433617 PMID:16897348 RGD:1598452 NCBI chrNW_004624750:5,881,065...5,954,799
Ensembl chrNW_004624750:5,881,091...5,952,300 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624759:3,258,324...3,315,265
Ensembl chrNW_004624759:3,276,741...3,312,601 		JBrowse link
G Ilk integrin linked kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624817:8,096,539...8,103,096
Ensembl chrNW_004624817:8,096,898...8,106,683 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 acts_upstream_of_or_within ISO (PMID:23980096) MGI PMID:23980096 NCBI chrNW_004624741:11,647,723...11,683,137
Ensembl chrNW_004624741:11,647,463...11,683,488 		JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit acts_upstream_of_or_within ISO (PMID:15563473) MGI PMID:15563473 NCBI chrNW_004624908:1,572,628...1,574,205
Ensembl chrNW_004624908:1,573,174...1,574,113 		JBrowse link
G Lmna lamin A/C ISO RGD PMID:22119912 RGD:10003161 NCBI chrNW_004624885:1,423,563...1,466,657
Ensembl chrNW_004624885:1,447,395...1,467,554 		JBrowse link
G LOC101724231 growth/differentiation factor 10 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624990:11,351...15,822 JBrowse link
G Lrp3 LDL receptor related protein 3 involved_in ISO (PMID:28340487) ARUK-UCL PMID:28340487 NCBI chrNW_004624794:9,892,300...9,904,320
Ensembl chrNW_004624794:9,892,690...9,904,261 		JBrowse link
G Lrp5 LDL receptor related protein 5 involved_in ISO (PMID:26891291) BHF-UCL PMID:26891291 NCBI chrNW_004624767:18,438,165...18,551,362
Ensembl chrNW_004624767:18,438,274...18,551,338 		JBrowse link
G Ltf lactotransferrin involved_in ISO (PMID:15166119) UniProt PMID:15166119 NCBI chrNW_004624730:74,636,554...74,656,817
Ensembl chrNW_004624730:74,636,522...74,656,886 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISO (PMID:21652706) UniProt PMID:21652706 NCBI chrNW_004624743:8,072,871...8,235,174
Ensembl chrNW_004624743:8,072,673...8,235,252 		JBrowse link
G Men1 menin 1 acts_upstream_of_or_within ISO (PMID:15150273) MGI PMID:15150273 NCBI chrNW_004624767:21,579,084...21,585,380
Ensembl chrNW_004624767:21,579,103...21,585,373 		JBrowse link
G Msx2 msh homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15175325) Ensembl
MGI		 PMID:15175325 GO_REF:0000107 NCBI chrNW_004624733:15,288,417...15,294,481
Ensembl chrNW_004624733:15,288,326...15,294,568 		JBrowse link
G Nell1 neural EGFL like 1 involved_in ISO (PMID:21723284) UniProt PMID:21723284 NCBI chrNW_004624766:11,921,570...12,734,032
Ensembl chrNW_004624766:11,921,650...12,737,576 		JBrowse link
G Npnt nephronectin involved_in ISO (PMID:19944102), (PMID:21689636) BHF-UCL PMID:19944102 PMID:21689636 NCBI chrNW_004624830:2,881,948...2,943,577
Ensembl chrNW_004624830:2,881,638...2,943,586 		JBrowse link
G Nppc natriuretic peptide C ISO RGD PMID:17562543 RGD:1642298 NCBI chrNW_004624843:4,869,278...4,873,444
Ensembl chrNW_004624843:4,869,614...4,873,448 		JBrowse link
G Pdlim7 PDZ and LIM domain 7 ISO RGD PMID:9832452 RGD:632731 NCBI chrNW_004624733:12,591,883...12,607,992
Ensembl chrNW_004624733:12,591,883...12,607,992 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624830:6,318,352...6,584,232
Ensembl chrNW_004624830:6,317,968...6,581,892 		JBrowse link
G Prkd1 protein kinase D1 involved_in ISO (PMID:19029091) UniProt PMID:19029091 NCBI chrNW_004624820:2,408,562...2,726,199
Ensembl chrNW_004624820:2,408,360...2,726,606 		JBrowse link
G Prmt3 protein arginine methyltransferase 3 involved_in ISO (PMID:31378783) UniProt PMID:31378783 NCBI chrNW_004624766:11,669,732...11,797,133
Ensembl chrNW_004624766:11,670,108...11,795,272 		JBrowse link
G Ptger4 prostaglandin E receptor 4 ISO RGD PMID:14751573 RGD:10043372 NCBI chrNW_004624759:14,243,887...14,259,090
Ensembl chrNW_004624759:14,244,899...14,258,445 		JBrowse link
G Runx2 RUNX family transcription factor 2 acts_upstream_of_or_within
involved_in		 ISO (PMID:15175325)
(PMID:15150273)
(PMID:28703881)
(PMID:18986983)		 MGI
UniProt		 PMID:15150273 PMID:15175325 PMID:18986983 PMID:28703881 NCBI chrNW_004624754:14,601,574...14,868,469
Ensembl chrNW_004624754:14,679,974...14,867,729 		JBrowse link
G Scube2 signal peptide, CUB domain and EGF like domain containing 2 acts_upstream_of_or_within ISO (PMID:25639508) MGI PMID:25639508 NCBI chrNW_004624766:1,158,607...1,241,797
Ensembl chrNW_004624766:1,151,793...1,241,774 		JBrowse link
G Scube3 signal peptide, CUB domain and EGF like domain containing 3 involved_in ISO (PMID:33308444) UniProt PMID:33308444 NCBI chrNW_004624754:22,164,319...22,196,569
Ensembl chrNW_004624754:22,166,578...22,196,540 		JBrowse link
G Sfrp2 secreted frizzled related protein 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:18166153) MGI
Ensembl		 PMID:18166153 GO_REF:0000107 NCBI chrNW_004624858:5,052,736...5,061,495
Ensembl chrNW_004624858:5,052,518...5,061,591 		JBrowse link
G Smad1 SMAD family member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15150273) MGI
Ensembl		 PMID:15150273 GO_REF:0000107 NCBI chrNW_004624853:4,415,816...4,503,317
Ensembl chrNW_004624853:4,444,876...4,502,496 		JBrowse link
G Smad5 SMAD family member 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15150273) Ensembl
MGI		 PMID:15150273 GO_REF:0000107 NCBI chrNW_004624733:10,927,264...10,983,049
Ensembl chrNW_004624733:10,931,061...10,983,669 		JBrowse link
G Sox11 SRY-box transcription factor 11 involved_in ISO (PMID:20626275) UniProt PMID:20626275 NCBI chrNW_004624846:4,043,010...4,046,660
Ensembl chrNW_004624846:4,044,893...4,046,248 		JBrowse link
G Suco SUN domain containing ossification factor involved_in ISO (PMID:20440000) UniProt PMID:20440000 NCBI chrNW_004624771:9,094,893...9,168,989
Ensembl chrNW_004624771:9,096,453...9,168,731 		JBrowse link
G Tent5a terminal nucleotidyltransferase 5A involved_in ISO (PMID:33882302) UniProt PMID:33882302 NCBI chrNW_004624799:12,829,562...12,836,850
Ensembl chrNW_004624799:12,829,528...12,834,511 		JBrowse link
G Tmem119 transmembrane protein 119 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624747:11,828,292...11,834,855 JBrowse link
G Tp63 tumor protein p63 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624730:67,283,444...67,489,808
Ensembl chrNW_004624730:67,286,160...67,489,670 		JBrowse link
G Vegfa vascular endothelial growth factor A acts_upstream_of_or_within ISO (PMID:22886301) MGI PMID:22886301 NCBI chrNW_004624754:15,929,414...15,943,637 JBrowse link
G Wnt10b Wnt family member 10B acts_upstream_of_or_within ISO (PMID:15728361), (PMID:19723499) MGI PMID:15728361 PMID:19723499 NCBI chrNW_004624816:3,221,573...3,227,102
Ensembl chrNW_004624816:3,210,828...3,227,096 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO (PMID:17720811) BHF-UCL PMID:17720811 NCBI chrNW_004624764:6,913,027...6,934,650
Ensembl chrNW_004624764:6,921,811...6,933,392 		JBrowse link
G Wnt7b Wnt family member 7B acts_upstream_of_or_within ISO (PMID:15576404) MGI PMID:15576404 NCBI chrNW_004624752:3,818,073...3,856,602
Ensembl chrNW_004624752:3,818,025...3,857,027 		JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 involved_in ISO (PMID:29496737) ARUK-UCL PMID:29496737 NCBI chrNW_004624730:26,813,716...26,967,615
Ensembl chrNW_004624730:26,813,624...26,967,691 		JBrowse link
G Yap1 Yes1 associated transcriptional regulator involved_in ISO (PMID:29496737) ARUK-UCL PMID:29496737 NCBI chrNW_004624878:621,214...776,363 JBrowse link
G Zhx3 zinc fingers and homeoboxes 3 involved_in ISO (PMID:21174497) UniProt PMID:21174497 NCBI chrNW_004624919:1,802,708...1,972,676
Ensembl chrNW_004624919:1,808,819...1,971,778 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17640
    positive regulation of biological process 6138
      positive regulation of cellular process 5838
        positive regulation of cell differentiation 934
          positive regulation of osteoblast differentiation 73
Path 2
Term Annotations click to browse term
  biological_process 17640
    developmental process 6390
      cellular developmental process 4304
        cell differentiation 4303
          regulation of cell differentiation 1583
            regulation of osteoblast differentiation 143
              positive regulation of osteoblast differentiation 73
paths to the root