Bmp6 (bone morphogenetic protein 6) - Rat Genome Database

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Gene: Bmp6 (bone morphogenetic protein 6) Heterocephalus glaber
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Symbol: Bmp6
Name: bone morphogenetic protein 6
RGD ID: 18917059
Description: ENCODES a protein that exhibits BMP receptor binding (ortholog); growth factor activity (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN BMP signaling pathway (ortholog); bone development (ortholog); cellular response to BMP stimulus (ortholog); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; ASSOCIATED WITH Acute Otitis Media (ortholog); adult T-cell leukemia/lymphoma (ortholog); allergic contact dermatitis (ortholog); FOUND IN extracellular space (ortholog); vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475617,743,834 - 17,894,753 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475617,742,822 - 17,894,931 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
BMP signaling pathway  (ISO)
bone development  (ISO)
cellular response to BMP stimulus  (ISO)
cellular response to iron ion  (ISO)
cellular response to mechanical stimulus  (ISO)
endochondral ossification  (ISO)
eye development  (ISO)
immune response  (ISO)
inflammatory response  (ISO)
intracellular iron ion homeostasis  (ISO)
kidney development  (ISO)
male genitalia development  (ISO)
multicellular organismal-level iron ion homeostasis  (ISO)
negative regulation of adherens junction organization  (ISO)
negative regulation of cell-cell adhesion mediated by cadherin  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
neuron differentiation  (ISO)
ossification  (ISO)
osteoblast differentiation  (ISO)
positive regulation of aldosterone biosynthetic process  (ISO)
positive regulation of aldosterone secretion  (ISO)
positive regulation of bone mineralization  (ISO)
positive regulation of chondrocyte differentiation  (ISO)
positive regulation of endothelial cell differentiation  (ISO)
positive regulation of endothelial cell proliferation  (ISO)
positive regulation of epithelial cell proliferation  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of lipopolysaccharide-mediated signaling pathway  (ISO)
positive regulation of neuron differentiation  (ISO)
positive regulation of osteoblast differentiation  (ISO)
positive regulation of peptidyl-tyrosine phosphorylation  (ISO)
positive regulation of SMAD protein signal transduction  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of vascular permeability  (ISO)
response to activity  (ISO)
response to glucocorticoid  (ISO)
response to iron ion  (ISO)
response to magnesium ion  (ISO)
response to retinoic acid  (ISO)
type B pancreatic cell development  (ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Bmp6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475617,743,834 - 17,894,753 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475617,742,822 - 17,894,931 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
BMP6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3867,726,099 - 7,881,728 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl67,726,099 - 7,881,728 (+)EnsemblGRCh38hg38GRCh38
GRCh3767,726,332 - 7,881,961 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3667,672,010 - 7,826,960 (+)NCBINCBI36Build 36hg18NCBI36
Build 3467,672,008 - 7,826,726NCBI
Celera68,956,438 - 9,111,399 (+)NCBICelera
Cytogenetic Map6p24.3NCBI
HuRef67,604,128 - 7,759,039 (+)NCBIHuRef
CHM1_167,728,829 - 7,884,079 (+)NCBICHM1_1
T2T-CHM13v2.067,594,835 - 7,750,477 (+)NCBIT2T-CHM13v2.0
Bmp6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391338,529,098 - 38,684,283 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1338,529,083 - 38,684,278 (+)EnsemblGRCm39 Ensembl
GRCm381338,345,716 - 38,500,314 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1338,345,107 - 38,500,302 (+)EnsemblGRCm38mm10GRCm38
MGSCv371338,437,585 - 38,591,597 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361338,353,182 - 38,507,194 (+)NCBIMGSCv36mm8
Celera1339,464,167 - 39,615,905 (+)NCBICelera
Cytogenetic Map13A3.3NCBI
cM Map1318.15NCBI
Bmp6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81726,523,704 - 26,785,558 (-)NCBIGRCr8
mRatBN7.21726,318,121 - 26,469,691 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1726,318,569 - 26,470,365 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1726,176,967 - 26,326,912 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01727,780,553 - 27,930,507 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01726,125,854 - 26,275,216 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01726,955,142 - 27,112,820 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1726,955,142 - 27,112,820 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01728,870,345 - 29,029,564 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41732,380,199 - 32,689,295 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11732,383,039 - 32,692,136 (-)NCBI
Celera1725,955,026 - 26,103,008 (-)NCBICelera
RH 3.4 Map17342.3RGD
Cytogenetic Map17p12NCBI
Bmp6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554656,054,931 - 6,200,377 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554656,053,600 - 6,201,254 (-)NCBIChiLan1.0ChiLan1.0
BMP6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2522,365,813 - 22,522,551 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1618,363,471 - 18,519,549 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v067,564,164 - 7,720,341 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.167,848,255 - 8,002,030 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl67,848,249 - 8,000,649 (+)Ensemblpanpan1.1panPan2
BMP6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1357,780,763 - 7,833,095 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl357,804,231 - 7,831,845 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha357,690,267 - 7,840,113 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0357,770,103 - 7,915,608 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl357,770,103 - 7,915,377 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1357,622,630 - 7,772,359 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0357,648,291 - 7,798,326 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0358,982,152 - 9,131,717 (+)NCBIUU_Cfam_GSD_1.0
Bmp6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494616,438,976 - 16,602,907 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365344,709,064 - 4,871,023 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365344,707,658 - 4,871,865 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BMP6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl75,058,817 - 5,210,270 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.175,058,817 - 5,208,868 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.275,163,209 - 5,313,233 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BMP6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11764,279,243 - 64,436,356 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1764,280,609 - 64,435,382 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660447,712,261 - 7,873,910 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000021518   ⟹   ENSHGLP00000021310
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475617,743,834 - 17,894,753 (-)Ensembl
RefSeq Acc Id: XM_004847720   ⟹   XP_004847777
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475617,742,822 - 17,894,931 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004847777 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000021310
RefSeq Acc Id: XP_004847777   ⟸   XM_004847720
Ensembl Acc Id: ENSHGLP00000021310   ⟸   ENSHGLT00000021518


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000015229 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000021518 ENTREZGENE
NCBI Gene Bmp6 ENTREZGENE