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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of regulatory T cell differentiation
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Accession:GO:0045590 term browser browse the term
Definition:Any process that stops, prevents, or reduces the rate of differentiation of regulatory T cells.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: down regulation of regulatory T cell differentiation;   downregulation of regulatory T cell differentiation;   negative regulation of regulatory T lymphocyte differentiation;   negative regulation of suppressor T cell differentiation
 narrow_synonym: inhibition of regulatory T cell differentiation
 related_synonym: negative regulation of regulatory T cell development

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negative regulation of regulatory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd44 CD44 molecule (IN blood group) involved_in ISO (MGI:5688819|PMID:25065622) UniProt PMID:25065622 MGI:5688819 NCBI chrNW_004624767:11,938,452...12,024,970
Ensembl chrNW_004624767:11,938,028...12,025,069 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte associated protein 4 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624765:12,449,205...12,454,324
Ensembl chrNW_004624765:12,449,205...12,454,324 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 ISO RGD PMID:30287503 RGD:38549580 NCBI chrNW_004624740:14,940,161...14,941,561
Ensembl chrNW_004624740:14,939,445...14,941,819 		JBrowse link
G Irf1 interferon regulatory factor 1 involved_in ISO (MGI:3803082|PMID:18641303) UniProt PMID:18641303 MGI:3803082 NCBI chrNW_004624733:39,596,565...39,603,428
Ensembl chrNW_004624733:39,596,501...39,603,526 		JBrowse link
G Lag3 lymphocyte activating 3 involved_in ISO (MGI:3510279|PMID:15485628) UniProt PMID:15485628 MGI:3510279 NCBI chrNW_004624860:3,454,587...3,461,649
Ensembl chrNW_004624860:3,456,347...3,461,592 		JBrowse link
G Mdk midkine involved_in ISO (PMID:22323540) UniProt PMID:22323540 NCBI chrNW_004624767:2,171,096...2,173,436
Ensembl chrNW_004624767:2,171,096...2,173,512 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:3806904|PMID:18713990) BHF-UCL PMID:18713990 MGI:3806904 NCBI chrNW_004624771:8,580,489...8,599,735 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15052
    immune system process 2108
      leukocyte activation 899
        lymphocyte activation 731
          lymphocyte differentiation 394
            T cell differentiation 293
              regulatory T cell differentiation 39
                negative regulation of regulatory T cell differentiation 7
                  negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation + 0
Path 2
Term Annotations click to browse term
  biological_process 15052
    cellular process 14191
      cellular developmental process 4126
        cell differentiation 4125
          cell development 2965
            hemopoiesis 930
              leukocyte differentiation 596
                mononuclear cell differentiation 483
                  lymphocyte differentiation 394
                    T cell differentiation 293
                      regulation of T cell differentiation 156
                        negative regulation of T cell differentiation 50
                          negative regulation of regulatory T cell differentiation 7
                            negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation + 0
paths to the root