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ONTOLOGY REPORT - ANNOTATIONS

Term:5'-3' DNA helicase activity
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Accession:GO:0043139 term browser browse the term
Definition:Unwinding a DNA helix in the 5' to 3' direction, driven by ATP hydrolysis.
Synonyms:exact_synonym: 5' to 3' DNA helicase activity;   ATP-dependent 5' to 3' DNA helicase activity;   ATP-dependent 5'-3' DNA helicase activity
 narrow_synonym: DNA helicase IV activity
 alt_id: GO:0008722;   GO:0043141
 xref: EC:5.6.2.3;   Reactome:R-HSA-6782131 "ERCC2-facilitated RNA Pol II backtracking in TC-NER"


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5'-3' DNA helicase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brip1 BRCA1 interacting helicase 1 enables ISO (PMID:14983014), (PMID:36608669) RGD PMID:14983014 PMID:36608669 NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324 		JBrowse link
G Ddx11 DEAD/H-box helicase 11 enables ISO (PMID:18499658) RGD PMID:18499658 NCBI chr 9:105,833,234...105,862,844
Ensembl chr 9:105,833,504...105,862,550 		JBrowse link
G Dna2 DNA replication helicase/nuclease 2 enables IEA
ISS		 GO_REF:0000107
GO_REF:0000024		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr20:25,661,652...25,690,598
Ensembl chr20:25,662,055...25,716,319 		JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit enables ISO (PMID:11445587), (PMID:8663148) RGD PMID:8663148 PMID:11445587 NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102 		JBrowse link
G Helb DNA helicase B enables ISO (PMID:12181327) RGD PMID:12181327 NCBI chr 7:55,588,510...55,615,979
Ensembl chr 7:55,588,798...55,615,585 		JBrowse link
G Ighmbp2 immunoglobulin mu DNA binding protein 2 enables ISS
ISO
IEA
IBA		 GO_REF:0000024
(PMID:19158098)
GO_REF:0000107
GO_REF:0000033		 UniProt
RGD
Ensembl
GO_Central		 PMID:19158098 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:200,506,641...200,529,293
Ensembl chr 1:200,506,338...200,529,514 		JBrowse link
G Pif1 PIF1 5'-to-3' DNA helicase enables ISO
IBA		 (PMID:16522649)
GO_REF:0000033		 RGD
GO_Central		 PMID:16522649 GO_REF:0000033 NCBI chr 8:66,110,641...66,120,202
Ensembl chr 8:66,111,072...66,120,200 		JBrowse link
G Slc25a16 solute carrier family 25 member 16 enables IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:25,691,474...25,717,558
Ensembl chr20:25,662,055...25,716,319 		JBrowse link
G Twnk twinkle mtDNA helicase enables ISO (PMID:12975372), (PMID:15167897), (PMID:18971204), (PMID:34950192) RGD PMID:12975372 PMID:15167897 PMID:18971204 PMID:34950192 NCBI chr 1:243,867,568...243,874,802
Ensembl chr 1:243,868,330...243,874,802 		JBrowse link
G Zgrf1 zinc finger, GRF-type containing 1 enables ISO (PMID:32640219) RGD PMID:32640219 NCBI chr 2:216,012,911...216,075,608
Ensembl chr 2:216,013,005...216,074,750 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20483
    ATP-dependent activity 628
      helicase activity 153
        DNA helicase activity 64
          5'-3' DNA helicase activity 10
Path 2
Term Annotations click to browse term
  molecular_function 20483
    catalytic activity 6036
      catalytic activity, acting on a nucleic acid 630
        catalytic activity, acting on DNA 254
          ATP-dependent activity, acting on DNA 126
            DNA helicase activity 64
              5'-3' DNA helicase activity 10
paths to the root