Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:protein refolding
go back to main search page
Accession:GO:0042026 term browser browse the term
Definition:The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
Synonyms:related_synonym: heat shock protein activity


show annotations for term's descendants           Sort by:
protein refolding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2M beta-2-microglobulin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16920948) Ensembl
MGI		 PMID:16920948 GO_REF:0000107 NCBI chr15:23,668,108...23,674,791
Ensembl chr15:41,836,345...41,842,991 		JBrowse link
G CCT6A chaperonin containing TCP1 subunit 6A involved_in IEA InterPro GO_REF:0000002 NCBI chr 7:56,664,757...56,677,000
Ensembl chr 7:57,087,072...57,098,613 		JBrowse link
G CRYAA crystallin alpha A involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr21:29,414,308...29,480,655
Ensembl chr21:42,782,991...42,786,794 		JBrowse link
G CRYAB crystallin alpha B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:106,795,406...106,800,019
Ensembl chr11:110,639,442...110,644,272 		JBrowse link
G DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:32,800,077...32,814,745
Ensembl chr 9:33,608,502...33,622,275 		JBrowse link
G DNAJA2 DnaJ heat shock protein family (Hsp40) member A2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:27,223,414...27,240,726
Ensembl chr16:46,113,088...46,130,028 		JBrowse link
G DNAJA4 DnaJ heat shock protein family (Hsp40) member A4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr15:57,193,545...57,211,518
Ensembl chr15:76,158,155...76,176,089 		JBrowse link
G DNAJB2 DnaJ heat shock protein family (Hsp40) member B2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr2B:106,536,846...106,544,430
Ensembl chr2B:225,127,967...225,135,556 		JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:15603737), (PMID:21231916)
(PMID:27708256)		 BHF-UCL
UniProt		 PMID:15603737 PMID:21231916 PMID:27708256 NCBI chr 6:31,476,710...31,491,411 JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:15603737), (PMID:21231916)
(PMID:27708256)		 BHF-UCL
UniProt		 PMID:15603737 PMID:21231916 PMID:27708256 NCBI chr 6:31,488,882...31,491,412 JBrowse link
G HSPA1L heat shock protein family A (Hsp70) member 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,470,745...31,483,615
Ensembl chr 6:32,358,054...32,359,979 		JBrowse link
G HSPA2 heat shock protein family A (Hsp70) member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:45,124,326...45,127,105
Ensembl chr14:63,373,840...63,375,762 		JBrowse link
G HSPA6 heat shock protein family A (Hsp70) member 6 involved_in ISO (PMID:21231916) UniProt PMID:21231916 NCBI chr 1:136,911,131...136,914,319 JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:117,890,545...117,895,262
Ensembl chr11:121,809,800...121,815,773 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:67,716,021...67,717,762
Ensembl chr 7:82,751,523...82,752,984 		JBrowse link
G HSPB2 heat shock protein family B (small) member 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:106,798,674...106,800,861
Ensembl chr11:110,642,933...110,644,893 		JBrowse link
G HSPB6 heat shock protein family B (small) member 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:32,684,355...32,686,833
Ensembl chr19:41,419,608...41,420,972 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 involved_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr2B:84,729,615...84,743,352
Ensembl chr2B:202,623,497...202,636,959 		JBrowse link
G LOC100975678 60 kDa heat shock protein, mitochondrial-like involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:88,495,584...88,497,585 JBrowse link
negative regulation of protein refolding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG5 BAG cochaperone 5 involved_in ISO PMID:15603737 BHF-UCL PMID:15603737 RGD:8553807 NCBI chr14:84,182,879...84,189,180
Ensembl chr14:103,997,524...103,998,927 		JBrowse link
G PDCL phosducin like ISO RGD PMID:12060742 RGD:633730 NCBI chr 9:93,949,613...93,959,913
Ensembl chr 9:122,283,877...122,294,174 		JBrowse link
G ST13 ST13 Hsp70 interacting protein ISO RGD PMID:9183013 RGD:2326107 NCBI chr22:21,719,713...21,751,912
Ensembl chr22:39,815,337...39,848,049 		JBrowse link
positive regulation of protein refolding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:11360998 RGD:10059391 NCBI chr11:117,890,545...117,895,262
Ensembl chr11:121,809,800...121,815,773 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16447
    cellular process 15485
      protein folding 183
        protein refolding 22
          negative regulation of protein refolding 3
          positive regulation of protein refolding 1
          regulation of protein refolding + 4
Path 2
Term Annotations click to browse term
  biological_process 16447
    metabolic process 10323
      cellular metabolic process 8638
        cellular biosynthetic process 7012
          macromolecule biosynthetic process 6495
            gene expression 6067
              protein maturation 487
                protein folding 183
                  protein refolding 22
                    negative regulation of protein refolding 3
                    positive regulation of protein refolding 1
                    regulation of protein refolding + 4
paths to the root