CRYAB (crystallin alpha B) - Rat Genome Database

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Gene: CRYAB (crystallin alpha B) Pan paniscus
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Symbol: CRYAB
Name: crystallin alpha B
RGD ID: 12011816
Description: ENCODES a protein that exhibits cytoskeletal protein binding (ortholog); microtubule binding (ortholog); INVOLVED IN apoptotic process involved in morphogenesis (ortholog); camera-type eye development (ortholog); cellular response to gamma radiation (ortholog); ASSOCIATED WITH ataxia telangiectasia (ortholog); BH4-deficient hyperphenylalaninemia A (ortholog); cardiomyopathy (ortholog); FOUND IN actin filament bundle (ortholog); axon (ortholog); cardiac myofibril (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: alpha-crystallin B chain
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29112,659,159 - 112,682,506 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111113,753,439 - 113,756,529 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011106,795,406 - 106,800,019 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111110,639,442 - 110,644,245 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11110,639,442 - 110,644,272 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CRYAB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29112,659,159 - 112,682,506 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111113,753,439 - 113,756,529 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011106,795,406 - 106,800,019 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111110,639,442 - 110,644,245 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11110,639,442 - 110,644,272 (-)Ensemblpanpan1.1panPan2
CRYAB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811111,908,564 - 111,923,740 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11111,908,564 - 111,923,722 (-)EnsemblGRCh38hg38GRCh38
GRCh3711111,779,288 - 111,794,464 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611111,284,560 - 111,287,683 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411111,284,559 - 111,287,683NCBI
Celera11108,932,558 - 108,935,681 (-)NCBICelera
Cytogenetic Map11q23.1NCBI
HuRef11107,703,256 - 107,706,379 (-)NCBIHuRef
CHM1_111111,662,430 - 111,665,553 (-)NCBICHM1_1
T2T-CHM13v2.011111,918,808 - 111,933,984 (-)NCBIT2T-CHM13v2.0
Cryab
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39950,657,251 - 50,667,936 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl950,662,625 - 50,667,936 (+)EnsemblGRCm39 Ensembl
GRCm38950,745,951 - 50,756,636 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl950,751,325 - 50,756,636 (+)EnsemblGRCm38mm10GRCm38
MGSCv37950,560,863 - 50,564,738 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36950,504,988 - 50,508,863 (+)NCBIMGSCv36mm8
Celera948,039,922 - 48,043,797 (+)NCBICelera
Cytogenetic Map9A5.3NCBI
cM Map927.75NCBI
Cryab
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8859,989,885 - 59,995,532 (+)NCBIGRCr8
mRatBN7.2851,093,441 - 51,099,161 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl851,093,441 - 51,099,157 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx856,601,359 - 56,605,151 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0854,880,286 - 54,884,078 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0852,744,541 - 52,748,333 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0855,178,543 - 55,182,546 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl855,178,289 - 55,182,545 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0853,776,100 - 53,779,780 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4854,107,824 - 54,111,502 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1854,126,302 - 54,130,559 (+)NCBI
Celera850,642,744 - 50,646,745 (+)NCBICelera
Cytogenetic Map8q23NCBI
Cryab
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541213,625,363 - 13,640,426 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541213,626,018 - 13,629,495 (-)NCBIChiLan1.0ChiLan1.0
CRYAB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1521,181,836 - 21,185,164 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl521,179,936 - 21,360,132 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha521,104,096 - 21,107,406 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0521,204,772 - 21,208,082 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl521,204,907 - 21,208,076 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1521,266,069 - 21,269,377 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0521,166,521 - 21,169,831 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0521,215,316 - 21,218,626 (+)NCBIUU_Cfam_GSD_1.0
Cryab
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494794,169,136 - 94,173,881 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366122,532,812 - 2,537,495 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366122,532,851 - 2,536,473 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CRYAB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl939,638,506 - 39,643,530 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1939,638,505 - 39,643,530 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2944,428,979 - 44,433,758 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CRYAB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11103,258,715 - 103,263,274 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1103,257,347 - 103,261,990 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604322,707,897 - 22,722,116 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cryab
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247847,074,590 - 7,093,054 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247847,074,590 - 7,093,471 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000062976   ⟹   ENSPPAP00000040063
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11110,639,442 - 110,644,272 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000062985   ⟹   ENSPPAP00000040072
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11110,640,984 - 110,642,524 (-)Ensembl
RefSeq Acc Id: XM_003805460   ⟹   XP_003805508
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29112,659,159 - 112,664,002 (-)NCBI
NHGRI_mPanPan111113,753,439 - 113,756,529 (-)NCBI
Mhudiblu_PPA_v011106,795,406 - 106,800,019 (-)NCBI
PanPan1.111110,639,442 - 110,644,245 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034933659   ⟹   XP_034789550
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29112,659,159 - 112,661,372 (-)NCBI
NHGRI_mPanPan111113,753,439 - 113,755,600 (-)NCBI
Mhudiblu_PPA_v011106,795,406 - 106,797,575 (-)NCBI
RefSeq Acc Id: XM_063608785   ⟹   XP_063464855
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29112,659,159 - 112,664,002 (-)NCBI
RefSeq Acc Id: XM_063608786   ⟹   XP_063464856
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29112,659,159 - 112,682,506 (-)NCBI
RefSeq Acc Id: XM_063608787   ⟹   XP_063464857
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29112,659,159 - 112,663,396 (-)NCBI
RefSeq Acc Id: XP_003805508   ⟸   XM_003805460
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CGA6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034789550   ⟸   XM_034933659
- Peptide Label: isoform X2
Ensembl Acc Id: ENSPPAP00000040072   ⟸   ENSPPAT00000062985
Ensembl Acc Id: ENSPPAP00000040063   ⟸   ENSPPAT00000062976
RefSeq Acc Id: XP_063464856   ⟸   XM_063608786
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CGA6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063464855   ⟸   XM_063608785
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CGA6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063464857   ⟸   XM_063608787
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CGA6 (UniProtKB/TrEMBL)
Protein Domains
sHSP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000042685 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000062976.1 UniProtKB/TrEMBL
  ENSPPAT00000062985.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.790 UniProtKB/TrEMBL
InterPro A-crystallin/Hsp20_dom UniProtKB/TrEMBL
  ACD_alphaB-crystallin UniProtKB/TrEMBL
  Alpha-crystallin/sHSP_animal UniProtKB/TrEMBL
  Alpha-crystallin_N UniProtKB/TrEMBL
  HSP20-like_chaperone UniProtKB/TrEMBL
KEGG Report pps:100972736 UniProtKB/TrEMBL
NCBI Gene CRYAB ENTREZGENE
PANTHER ALPHA-CRYSTALLIN B CHAIN UniProtKB/TrEMBL
  PTHR45640 UniProtKB/TrEMBL
Pfam Crystallin UniProtKB/TrEMBL
  HSP20 UniProtKB/TrEMBL
PIRSF Sm_HSP_B1 UniProtKB/TrEMBL
PRINTS ACRYSTALLIN UniProtKB/TrEMBL
PROSITE SHSP UniProtKB/TrEMBL
Superfamily-SCOP SSF49764 UniProtKB/TrEMBL
UniProt A0A2R9CGA6 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CP10_PANPA UniProtKB/TrEMBL