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ONTOLOGY REPORT - ANNOTATIONS

Term:toll-like receptor TLR6:TLR2 signaling pathway
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Accession:GO:0038124 term browser browse the term
Definition:The series of molecular signals initiated by a ligand binding of a heterodimeric TLR6:TLR2 complex, followed by transmission of the signal by the activated receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: TLR2:TLR6 signaling pathway;   toll-like receptor TLR6:TLR2 signalling pathway


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toll-like receptor TLR6:TLR2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISO (PMID:36964784) RGD PMID:36964784 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in ISO (PMID:27708357) RGD PMID:27708357 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tlr2 toll-like receptor 2 involved_in ISO (PMID:23626692) RGD PMID:23626692 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO (PMID:23626692) RGD PMID:23626692 NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    immune system process 3002
      activation of immune response 576
        activation of innate immune response 314
          innate immune response-activating signaling pathway 287
            pattern recognition receptor signaling pathway 276
              toll-like receptor signaling pathway 78
                toll-like receptor TLR6:TLR2 signaling pathway 4
Path 2
Term Annotations click to browse term
  biological_process 20069
    response to stimulus 10792
      response to biotic stimulus 1910
        response to external biotic stimulus 1863
          response to other organism 1859
            defense response to other organism 1311
              defense response to symbiont 1177
                innate immune response 1005
                  regulation of innate immune response 480
                    positive regulation of innate immune response 386
                      activation of innate immune response 314
                        innate immune response-activating signaling pathway 287
                          pattern recognition receptor signaling pathway 276
                            toll-like receptor signaling pathway 78
                              toll-like receptor TLR6:TLR2 signaling pathway 4
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