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calcitriol biosynthetic process from calciol - Ontology Report - Rat Genome Database

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ONTOLOGY REPORT - ANNOTATIONS

Term:calcitriol biosynthetic process from calciol
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Accession:GO:0036378 term browser browse the term
Definition:Conversion of vitamin D3 from its largely inactive form (calciol, also called cholecalciferol) into a hormonally active form (calcitriol). Conversion requires 25-hydroxylation of calciol in the liver to form calcidiol, and subsequent 1,alpha-hydroxylation of calcidiol in the kidney to form calcitriol.
Synonyms:exact_synonym: calcitriol biosynthesis from calciol;   vitamin D3 activation
 broad_synonym: 1alpha,25(OH)2D3 biosynthesis;   1alpha,25-dihydroxycholecalciferol biosynthesis;   1alpha,25-dihydroxyvitamin D3 biosynthesis

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calcitriol biosynthetic process from calciol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 involved_in IEA GOC GO_REF:0000108 NCBI chr20:50,500,103...50,520,487
Ensembl chr20:51,721,685...51,742,716 		JBrowse link
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:106,042,235...106,076,840
Ensembl chr2B:224,637,238...224,671,474 		JBrowse link
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:31,158,814...31,164,462
Ensembl chr12:31,419,773...31,424,822 		JBrowse link
G CYP2R1 cytochrome P450 family 2 subfamily R member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:14,960,651...14,989,083
Ensembl chr11:14,656,939...14,671,584 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 involved_in IEA GOC GO_REF:0000108 NCBI chr 7:91,797,037...91,824,696
Ensembl chr 7:105,230,666...105,258,401 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    cellular process 18868
      metabolic process 12795
        biosynthetic process 9694
          lipid biosynthetic process 688
            steroid biosynthetic process 154
              vitamin D biosynthetic process 11
                calcitriol biosynthetic process from calciol 5
Path 2
Term Annotations click to browse term
  biological_process 19315
    cellular process 18868
      metabolic process 12795
        primary metabolic process 11190
          lipid metabolic process 1320
            steroid metabolic process 314
              steroid biosynthetic process 154
                vitamin D biosynthetic process 11
                  calcitriol biosynthetic process from calciol 5
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