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ONTOLOGY REPORT - ANNOTATIONS

Term:toll-like receptor 5 signaling pathway
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Accession:GO:0034146 term browser browse the term
Definition:The series of molecular signals initiated by a ligand binding to toll-like receptor 5.
Synonyms:exact_synonym: TLR5 signaling pathway;   toll-like receptor 5 signalling pathway


show annotations for term's descendants           Sort by:
toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myd88 myeloid differentiation primary response gene 88 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477 		JBrowse link
G Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein NOT|involved_in IMP (PMID:12447442) BHF-UCL PMID:12447442 NCBI chr 9:35,095,687...35,111,587
Ensembl chr 9:35,095,847...35,111,587 		JBrowse link
G Tlr5 toll-like receptor 5 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 1:182,782,317...182,804,010
Ensembl chr 1:182,782,353...182,804,010 		JBrowse link
negative regulation of toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfaip3 tumor necrosis factor, alpha-induced protein 3 involved_in IDA (PMID:19912257) BHF-UCL PMID:19912257 NCBI chr10:18,876,658...18,891,158
Ensembl chr10:18,876,658...18,891,405 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28636
    immune system process 3157
      activation of immune response 628
        immune response-activating signaling pathway 544
          immune response-activating cell surface receptor signaling pathway 326
            innate immune response activating cell surface receptor signaling pathway 98
              cell surface pattern recognition receptor signaling pathway 87
                cell surface toll-like receptor signaling pathway 81
                  toll-like receptor 5 signaling pathway 4
                    negative regulation of toll-like receptor 5 signaling pathway 1
                    positive regulation of toll-like receptor 5 signaling pathway 0
                    regulation of toll-like receptor 5 signaling pathway + 1
Path 2
Term Annotations click to browse term
  biological_process 28636
    response to stimulus 10959
      response to external stimulus 3009
        response to external biotic stimulus 2077
          response to other organism 2073
            defense response to other organism 1466
              defense response to symbiont 1336
                innate immune response 1147
                  regulation of innate immune response 532
                    positive regulation of innate immune response 429
                      activation of innate immune response 348
                        innate immune response-activating signaling pathway 318
                          innate immune response activating cell surface receptor signaling pathway 98
                            cell surface pattern recognition receptor signaling pathway 87
                              cell surface toll-like receptor signaling pathway 81
                                toll-like receptor 5 signaling pathway 4
                                  negative regulation of toll-like receptor 5 signaling pathway 1
                                  positive regulation of toll-like receptor 5 signaling pathway 0
                                  regulation of toll-like receptor 5 signaling pathway + 1
paths to the root