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ONTOLOGY REPORT - ANNOTATIONS

Term:nuclear DNA replication
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Accession:GO:0033260 term browser browse the term
Definition:The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.
Synonyms:exact_synonym: DNA replication involved in S phase;   nuclear cell cycle DNA replication
 related_synonym: DNA replication during S phase
 only_in_taxon: NCBITaxon:2759 ! Eukaryota

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nuclear DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family AAA domain containing 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936538:2,815,370...2,877,084
Ensembl chrNW_004936538:2,811,174...2,874,113 		JBrowse link
G Donson DNA replication fork stabilization factor DONSON involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936500:8,712,168...8,720,728
Ensembl chrNW_004936500:8,712,205...8,739,953 		JBrowse link
G Znf830 zinc finger protein 830 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21191184) Ensembl
TreeGrafter
MGI		 PMID:21191184 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936538:243,557...245,353
Ensembl chrNW_004936538:244,188...245,300 		JBrowse link
DNA replication preinitiation complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936641:916,695...925,411
Ensembl chrNW_004936641:917,435...920,981 		JBrowse link
G Gmnn geminin DNA replication inhibitor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936671:1,017,621...1,027,224
Ensembl chrNW_004936671:1,018,124...1,026,968 		JBrowse link
DNA strand elongation involved in mitotic DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gins1 GINS complex subunit 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936620:421,845...446,853
Ensembl chrNW_004936620:422,230...446,753 		JBrowse link
DNA synthesis involved in mitotic DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk2 cyclin dependent kinase 2 ISO RGD PMID:15696186 RGD:2301349 NCBI chrNW_004936646:379,849...385,648
Ensembl chrNW_004936646:379,842...385,877 		JBrowse link
G Tk1 thymidine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936594:2,784,891...2,794,693
Ensembl chrNW_004936594:2,784,226...2,794,830 		JBrowse link
mitotic DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mcm6 minichromosome maintenance complex component 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936469:40,014,892...40,059,571
Ensembl chrNW_004936469:40,014,863...40,059,580 		JBrowse link
mitotic DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gins3 GINS complex subunit 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936475:10,209,127...10,216,701
Ensembl chrNW_004936475:10,209,071...10,218,051 		JBrowse link
G Mcm2 minichromosome maintenance complex component 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936798:756,350...768,600
Ensembl chrNW_004936798:756,588...765,338 		JBrowse link
G Mcm3 minichromosome maintenance complex component 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936476:8,530,614...8,547,971
Ensembl chrNW_004936476:8,530,688...8,547,978 		JBrowse link
G Mcm4 minichromosome maintenance complex component 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936590:4,705,028...4,722,320
Ensembl chrNW_004936590:4,704,972...4,722,427 		JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004936836:1,151...287,438 JBrowse link
mitotic DNA replication preinitiation complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc45 cell division cycle 45 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936619:3,420,110...3,452,419
Ensembl chrNW_004936619:3,420,191...3,452,436 		JBrowse link
mitotic DNA replication termination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtf2 replication termination factor 2 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936875:369,065...414,522
Ensembl chrNW_004936875:369,065...414,053 		JBrowse link
mitotic DNA-templated DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Recql5 RecQ like helicase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936594:829,296...862,615
Ensembl chrNW_004936594:828,475...862,912 		JBrowse link
mitotic recombination-dependent replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2 DNA repair associated involved_in ISO (PMID:21076401) BHF-UCL PMID:21076401 NCBI chrNW_004936472:26,945,659...27,017,693 JBrowse link
mitotic telomere maintenance via semi-conservative replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dna2 DNA replication helicase/nuclease 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936521:9,843,867...9,884,248
Ensembl chrNW_004936521:9,843,900...9,883,932 		JBrowse link
G Pcna proliferating cell nuclear antigen involved_in ISO (PMID:24115439) BHF-UCL PMID:24115439 NCBI chrNW_004936485:13,766,221...13,771,215 JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936514:10,920,979...10,954,483
Ensembl chrNW_004936514:10,922,322...10,954,402 		JBrowse link
Okazaki fragment processing involved in mitotic DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lig1 DNA ligase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936664:2,242,916...2,276,286
Ensembl chrNW_004936664:2,242,897...2,276,715 		JBrowse link
positive regulation of mitotic cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr1 fibroblast growth factor receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:2161540) Ensembl
MGI		 PMID:2161540 GO_REF:0000107 NCBI chrNW_004936710:1,760,365...1,815,269
Ensembl chrNW_004936710:1,760,089...1,815,508 		JBrowse link
positive regulation of nuclear cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atrx ATRX chromatin remodeler involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936683:2,496,307...2,718,539
Ensembl chrNW_004936683:2,495,959...2,718,620 		JBrowse link
G Cdc7 cell division cycle 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936537:7,445,882...7,515,196
Ensembl chrNW_004936537:7,488,776...7,514,322 		JBrowse link
G Dbf4 DBF4-CDC7 kinase regulatory subunit involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936763:963,195...987,198
Ensembl chrNW_004936763:963,195...986,926 		JBrowse link
G Dbf4b DBF4B-CDC7 kinase regulatory subunit involved_in ISO (PMID:15668232) UniProt PMID:15668232 NCBI chrNW_004936541:1,108,577...1,133,203 JBrowse link
G Ino80 INO80 complex ATPase subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:4,374,802...4,478,894
Ensembl chrNW_004936471:4,375,395...4,478,899 		JBrowse link
G Wiz WIZ zinc finger involved_in ISO (PMID:23545495) UniProt PMID:23545495 NCBI chrNW_004936596:5,061,674...5,084,931 JBrowse link
regulation of mitotic cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zmpste24 zinc metallopeptidase STE24 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15980864) Ensembl
MGI		 PMID:15980864 GO_REF:0000107 NCBI chrNW_004936474:22,035,059...22,077,846
Ensembl chrNW_004936474:22,034,801...22,077,986 		JBrowse link
regulation of nuclear cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation induced cytidine deaminase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936870:25,039...34,601
Ensembl chrNW_004936870:25,039...34,601 		JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11850834) Ensembl
MGI		 PMID:11850834 GO_REF:0000107 NCBI chrNW_004936641:916,695...925,411
Ensembl chrNW_004936641:917,435...920,981 		JBrowse link
G Dach1 dachshund family transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936511:8,899,245...9,253,024
Ensembl chrNW_004936511:9,061,676...9,253,486 		JBrowse link
G Ilkap ILK associated serine/threonine phosphatase ISO RGD PMID:9857069 RGD:632254 NCBI chrNW_004936525:303,436...322,677
Ensembl chrNW_004936525:303,499...322,563 		JBrowse link
G Nuggc nuclear GTPase, germinal center associated involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936675:885,015...931,657
Ensembl chrNW_004936675:885,039...920,253 		JBrowse link
telomere maintenance via semi-conservative replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Upf1 UPF1 RNA helicase and ATPase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936596:2,469,444...2,505,688
Ensembl chrNW_004936596:2,468,116...2,505,688 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16037
    cellular process 15650
      cell cycle process 1204
        cell cycle DNA replication 40
          nuclear DNA replication 35
            DNA replication preinitiation complex assembly + 3
            DNA strand elongation involved in nuclear cell cycle DNA replication + 1
            mitotic DNA replication + 16
            negative regulation of nuclear cell cycle DNA replication + 0
            nuclear DNA replication DNA duplex unwinding + 0
            nuclear DNA replication DNA ligation + 0
            nuclear DNA replication termination + 1
            nuclear cell cycle DNA replication initiation + 5
            positive regulation of nuclear cell cycle DNA replication + 7
            pre-replicative complex assembly involved in nuclear cell cycle DNA replication + 0
            premeiotic DNA replication + 0
            regulation of nuclear cell cycle DNA replication + 13
            telomere maintenance via semi-conservative replication + 4
Path 2
Term Annotations click to browse term
  biological_process 16037
    cellular process 15650
      metabolic process 9980
        primary metabolic process 8867
          nucleobase-containing compound metabolic process 4939
            nucleic acid metabolic process 4448
              DNA metabolic process 871
                DNA replication 257
                  DNA-templated DNA replication 151
                    cell cycle DNA replication 40
                      nuclear DNA replication 35
                        DNA replication preinitiation complex assembly + 3
                        DNA strand elongation involved in nuclear cell cycle DNA replication + 1
                        mitotic DNA replication + 16
                        negative regulation of nuclear cell cycle DNA replication + 0
                        nuclear DNA replication DNA duplex unwinding + 0
                        nuclear DNA replication DNA ligation + 0
                        nuclear DNA replication termination + 1
                        nuclear cell cycle DNA replication initiation + 5
                        positive regulation of nuclear cell cycle DNA replication + 7
                        pre-replicative complex assembly involved in nuclear cell cycle DNA replication + 0
                        premeiotic DNA replication + 0
                        regulation of nuclear cell cycle DNA replication + 13
                        telomere maintenance via semi-conservative replication + 4
paths to the root