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ONTOLOGY REPORT - ANNOTATIONS


Term:DNA replication preinitiation complex assembly
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Accession:GO:0071163 term browser browse the term
Definition:The aggregation, arrangement and bonding together of a set of components to form the DNA replication preinitiation complex, a protein-DNA complex that is assembled at DNA replication origins immediately prior to the initiation of DNA replication. The complex consists of proteins that initiate the DNA binding, melt the helix and enable helicase activity.
Synonyms:exact_synonym: DNA replication preinitiation complex formation;   pre-IC complex assembly
 alt_id: GO:1902293;   GO:1902316


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DNA replication preinitiation complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in IBA
ISO
PMID:21873635
(PMID:11125146)
RGD PMID:11125146, PMID:21873635 RGD:13792537 NCBI chr19:50,620,713...50,625,659 JBrowse link
G Gmnn geminin, DNA replication inhibitor involved_in ISO (PMID:11125146) RGD PMID:11125146 NCBI chr17:40,301,771...40,310,054 JBrowse link
mitotic DNA replication preinitiation complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc45 cell division cycle 45 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:82,185,427...82,210,630 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    cellular process 18342
      cell cycle process 1174
        DNA replication preinitiation complex assembly 3
          CMG complex assembly 0
          GINS complex assembly 0
          mitotic DNA replication preinitiation complex assembly 1
          premeiotic DNA replication preinitiation complex assembly 0
Path 2
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11795
      organic substance metabolic process 11334
        organic substance biosynthetic process 6025
          macromolecule biosynthetic process 5087
            cellular macromolecule biosynthetic process 5046
              DNA replication 254
                DNA-dependent DNA replication 152
                  cell cycle DNA replication 41
                    nuclear DNA replication 36
                      DNA replication preinitiation complex assembly 3
                        CMG complex assembly 0
                        GINS complex assembly 0
                        mitotic DNA replication preinitiation complex assembly 1
                        premeiotic DNA replication preinitiation complex assembly 0
paths to the root