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mast cell homeostasis - Ontology Report - Rat Genome Database

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ONTOLOGY REPORT - ANNOTATIONS

Term:mast cell homeostasis
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Accession:GO:0033023 term browser browse the term
Definition:The process of regulating the proliferation and elimination of mast cells such that the total number of mast cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
Comment:Note that this term represents the return of mast cell levels to stable numbers following an immune response as well as the proliferation and elimination of mast cells required to maintain stable numbers in the absence of an outside stimulus.

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show annotations for term's descendants           Sort by:
mast cell homeostasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc15a4 solute carrier family 15 member 4 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:29155995)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:29155995 GO_REF:0000024 GO_REF:0000107 NCBI chr12:34,684,583...34,718,429
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
mast cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1g Fc epsilon receptor Ig acts_upstream_of ISO MGI:2384004 (PMID:14764707) RGD PMID:14764707 NCBI chr13:86,181,908...86,186,766
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Il3 interleukin 3 acts_upstream_of ISO (PMID:12714518) RGD PMID:12714518 NCBI chr10:38,906,460...38,908,810
Ensembl chr10:38,405,716...38,408,066 		JBrowse link
G Kitlg KIT ligand acts_upstream_of ISO
IEA		 (PMID:12714518)
GO_REF:0000107		 RGD
Ensembl		 PMID:12714518 GO_REF:0000107 NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:34,896,053...34,977,214 		JBrowse link
G Nf1 neurofibromin 1 acts_upstream_of ISO
IEA		 MGI:96974|MGI:97583|MGI:99255 (PMID:15039234)
GO_REF:0000107		 RGD
Ensembl		 PMID:15039234 GO_REF:0000107 NCBI chr10:64,803,986...65,037,086
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of ISO
IEA		 MGI:1857249 (PMID:15947484)
GO_REF:0000107		 RGD
Ensembl		 PMID:15947484 GO_REF:0000107 NCBI chr10:86,285,859...86,310,187
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
negative regulation of mast cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1g Fc epsilon receptor Ig acts_upstream_of_or_within ISO MGI:2384004 (PMID:14764707) RGD PMID:14764707 NCBI chr13:86,181,908...86,186,766
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Il3 interleukin 3 acts_upstream_of_or_within ISO (PMID:12714518) RGD PMID:12714518 NCBI chr10:38,906,460...38,908,810
Ensembl chr10:38,405,716...38,408,066 		JBrowse link
G Kitlg KIT ligand acts_upstream_of_or_within ISO
IEA		 (PMID:12714518)
GO_REF:0000107		 RGD
Ensembl		 PMID:12714518 GO_REF:0000107 NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:34,896,053...34,977,214 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO
IEA		 MGI:1857249 (PMID:15947484)
GO_REF:0000107		 RGD
Ensembl		 PMID:15947484 GO_REF:0000107 NCBI chr10:86,285,859...86,310,187
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
positive regulation of mast cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nf1 neurofibromin 1 acts_upstream_of_or_within ISO
IEA		 MGI:96974|MGI:97583|MGI:99255 (PMID:15039234)
GO_REF:0000107		 RGD
Ensembl		 PMID:15039234 GO_REF:0000107 NCBI chr10:64,803,986...65,037,086
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
regulation of mast cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 involved_in ISO
IEA		 (PMID:14625290)
GO_REF:0000107		 RGD
Ensembl		 PMID:14625290 GO_REF:0000107 NCBI chr 6:46,601,583...46,663,690
Ensembl chr 6:40,872,856...40,920,639 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    immune system process 3132
      leukocyte homeostasis 141
        mast cell homeostasis 7
          mast cell apoptotic process + 6
Path 2
Term Annotations click to browse term
  biological_process 20567
    homeostatic process 2032
      multicellular organismal-level homeostasis 979
        homeostasis of number of cells 428
          leukocyte homeostasis 141
            mast cell homeostasis 7
              mast cell apoptotic process + 6
paths to the root