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ONTOLOGY REPORT - ANNOTATIONS

Term:Cul5-RING ubiquitin ligase complex
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Accession:GO:0031466 term browser browse the term
Definition:A ubiquitin ligase complex in which a cullin from the Cul5 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein.
Synonyms:exact_synonym: CDL5 complex;   CRL5 complex;   cullin-RING ligase 5
 broad_synonym: EC2S complex
 related_synonym: SCF5 complex

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Cul5-RING ubiquitin ligase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd9 ankyrin repeat domain 9 part_of ISO (PMID:30293565) UniProt PMID:30293565 NCBI chrNW_004955538:1,735,898...1,739,827 JBrowse link
G Arih2 ariadne RBR E3 ubiquitin protein ligase 2 located_in ISO (PMID:24076655) UniProt PMID:24076655 NCBI chrNW_004955532:933,749...1,008,619
Ensembl chrNW_004955532:933,749...1,008,619 		JBrowse link
G Asb11 ankyrin repeat and SOCS box containing 11 part_of ISO (PMID:31387940), (PMID:38574733) UniProt PMID:31387940 PMID:38574733 NCBI chrNW_004955519:2,875,287...2,896,122
Ensembl chrNW_004955519:2,875,212...2,896,191 		JBrowse link
G Asb4 ankyrin repeat and SOCS box containing 4 part_of ISO (PMID:17636018) UniProt PMID:17636018 NCBI chrNW_004955432:12,078,104...12,137,988
Ensembl chrNW_004955432:12,078,090...12,139,264 		JBrowse link
G Asb9 ankyrin repeat and SOCS box containing 9 part_of ISO (PMID:23837592), (PMID:32513959), (PMID:33268465) UniProt PMID:23837592 PMID:32513959 PMID:33268465 NCBI chrNW_004955519:2,902,802...2,941,358
Ensembl chrNW_004955519:2,902,802...2,941,433 		JBrowse link
G Cul5 cullin 5 part_of ISO (PMID:17636018), (PMID:21980433), (PMID:22405651), (PMID:23897481), (PMID:25505247), (PMID:31387940), (PMID:32513959), (PMID:33268465), (PMID:34518685), (PMID:38418882), (PMID:38574733)
(PMID:17974915), (PMID:24210661)		 UniProt PMID:17636018 PMID:17974915 PMID:21980433 PMID:22405651 PMID:23897481 More... NCBI chrNW_004955412:10,266,072...10,336,156
Ensembl chrNW_004955412:10,256,381...10,336,156 		JBrowse link
G Elob elongin B part_of ISO (PMID:17636018), (PMID:21980433), (PMID:23837592), (PMID:25505247), (PMID:31387940), (PMID:32513959), (PMID:33268465), (PMID:34857742), (PMID:37816714), (PMID:38418882)
(PMID:23897481)		 UniProt PMID:17636018 PMID:21980433 PMID:23837592 PMID:23897481 PMID:25505247 More... NCBI chrNW_004955442:14,498,666...14,501,895
Ensembl chrNW_004955442:14,498,725...14,502,135 		JBrowse link
G Eloc elongin C part_of ISO (PMID:21980433), (PMID:23837592), (PMID:25505247), (PMID:30166453), (PMID:31387940), (PMID:32513959), (PMID:33268465), (PMID:34857742), (PMID:37816714), (PMID:38418882)
(PMID:23897481)		 UniProt PMID:21980433 PMID:23837592 PMID:23897481 PMID:25505247 PMID:30166453 More... NCBI chrNW_004955444:6,400,721...6,415,881
Ensembl chrNW_004955444:6,400,832...6,415,881 		JBrowse link
G Klhdc1 kelch domain containing 1 is_active_in ISO (PMID:32200094) UniProt PMID:32200094 NCBI chrNW_004955409:12,914,446...12,970,266
Ensembl chrNW_004955409:12,912,303...12,970,474 		JBrowse link
G Pcmtd1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 part_of ISO (PMID:35486881) UniProt PMID:35486881 NCBI chrNW_004955454:11,445,684...11,481,076
Ensembl chrNW_004955454:11,445,182...11,481,893 		JBrowse link
G Rbx1 ring-box 1 part_of ISO (PMID:17636018) UniProt PMID:17636018 NCBI chrNW_004955413:26,579,759...26,592,980
Ensembl chrNW_004955413:26,579,759...26,592,980 		JBrowse link
G Rnf7 ring finger protein 7 part_of ISO (PMID:21980433), (PMID:22405651), (PMID:25505247), (PMID:31387940), (PMID:33268465), (PMID:34518685), (PMID:38418882), (PMID:38574733)
(PMID:24210661), (PMID:32513959)		 UniProt PMID:21980433 PMID:22405651 PMID:24210661 PMID:25505247 PMID:31387940 More... NCBI chrNW_004955508:4,001,441...4,003,518 JBrowse link
G Socs2 suppressor of cytokine signaling 2 part_of ISO (PMID:21980433), (PMID:23897481), (PMID:25505247), (PMID:31182716), (PMID:34857742), (PMID:37816714) UniProt PMID:21980433 PMID:23897481 PMID:25505247 PMID:31182716 PMID:34857742 More... NCBI chrNW_004955405:30,349,956...30,623,849
Ensembl chrNW_004955405:30,366,866...30,375,468
Ensembl chrNW_004955405:30,366,866...30,375,468 		JBrowse link
G Socs7 suppressor of cytokine signaling 7 part_of ISO (PMID:24210661) UniProt PMID:24210661 NCBI chrNW_004955451:13,567,377...13,595,685
Ensembl chrNW_004955451:13,567,377...13,595,685 		JBrowse link
G Spsb3 splA/ryanodine receptor domain and SOCS box containing 3 part_of ISO (PMID:29059170), (PMID:38418882) UniProt PMID:29059170 PMID:38418882 NCBI chrNW_004955442:15,486,845...15,493,422
Ensembl chrNW_004955442:15,487,475...15,493,422 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 12777
    protein-containing complex 4284
      intracellular protein-containing complex 738
        ubiquitin ligase complex 239
          cullin-RING ubiquitin ligase complex 149
            Cul5-RING ubiquitin ligase complex 15
Path 2
Term Annotations click to browse term
  cellular_component 12777
    protein-containing complex 4284
      catalytic complex 1360
        transferase complex 694
          ubiquitin ligase complex 239
            cullin-RING ubiquitin ligase complex 149
              Cul5-RING ubiquitin ligase complex 15
paths to the root