Socs7 (suppressor of cytokine signaling 7) - Rat Genome Database

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Gene: Socs7 (suppressor of cytokine signaling 7) Chinchilla lanigera
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Symbol: Socs7
Name: suppressor of cytokine signaling 7
RGD ID: 8884781
Description: ENCODES a protein that exhibits phosphorylation-dependent protein binding (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN cerebral cortex radially oriented cell migration (ortholog); fat cell differentiation (ortholog); insulin receptor signaling pathway (ortholog); PARTICIPATES IN insulin signaling pathway; Jak-Stat signaling pathway; ASSOCIATED WITH ovarian carcinoma (ortholog); FOUND IN Cul5-RING ubiquitin ligase complex (ortholog); cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545113,567,377 - 13,595,685 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545113,567,377 - 13,595,685 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Socs7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545113,567,377 - 13,595,685 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545113,567,377 - 13,595,685 (+)NCBIChiLan1.0ChiLan1.0
SOCS7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381738,351,844 - 38,405,593 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1738,351,844 - 38,405,593 (+)EnsemblGRCh38hg38GRCh38
GRCh371736,507,727 - 36,561,846 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361733,761,531 - 33,809,545 (+)NCBINCBI36Build 36hg18NCBI36
Celera1733,168,273 - 33,215,998 (+)NCBICelera
Cytogenetic Map17q12NCBI
HuRef1732,304,776 - 32,358,313 (+)NCBIHuRef
CHM1_11736,743,687 - 36,797,156 (+)NCBICHM1_1
T2T-CHM13v2.01739,214,750 - 39,268,637 (+)NCBIT2T-CHM13v2.0
Socs7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391197,253,044 - 97,289,368 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1197,253,261 - 97,289,368 (+)EnsemblGRCm39 Ensembl
GRCm381197,362,292 - 97,398,542 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1197,362,435 - 97,398,542 (+)EnsemblGRCm38mm10GRCm38
MGSCv371197,223,865 - 97,259,856 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361197,178,641 - 97,214,632 (+)NCBIMGSCv36mm8
Celera11106,997,950 - 107,050,631 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1160.96NCBI
Socs7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81082,848,525 - 82,885,201 (+)NCBIGRCr8
mRatBN7.21082,352,159 - 82,388,829 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1082,351,680 - 82,388,830 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01085,301,797 - 85,337,971 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1085,301,875 - 85,330,397 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01085,091,496 - 85,126,533 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41086,090,339 - 86,134,313 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11086,104,702 - 86,148,592 (+)NCBI
Celera1081,112,515 - 81,148,028 (+)NCBICelera
Cytogenetic Map10q31NCBI
SOCS7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21926,544,148 - 26,599,077 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11728,427,584 - 28,482,511 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01718,867,241 - 18,921,792 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11719,184,246 - 19,236,423 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1719,193,860 - 19,236,427 (-)Ensemblpanpan1.1panPan2
SOCS7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1923,775,349 - 23,809,325 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl923,776,827 - 23,803,994 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha923,237,225 - 23,269,741 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0924,562,862 - 24,595,403 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl924,567,638 - 24,595,660 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1923,333,880 - 23,366,157 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0923,594,969 - 23,627,506 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0923,721,544 - 23,754,076 (-)NCBIUU_Cfam_GSD_1.0
Socs7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560223,200,155 - 23,248,497 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649013,826,636 - 13,874,603 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649013,826,642 - 13,874,984 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SOCS7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1223,688,722 - 23,723,363 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11223,687,115 - 23,723,427 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21263,548,726 - 63,584,747 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SOCS7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11667,784,644 - 67,839,456 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1667,794,258 - 67,839,040 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607738,813,139 - 38,868,989 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Socs7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247954,159,402 - 4,186,037 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247954,159,493 - 4,185,677 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000022413   ⟹   ENSCLAP00000022208
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495545113,567,377 - 13,595,685 (+)Ensembl
RefSeq Acc Id: XM_013519430   ⟹   XP_013374884
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495545113,567,377 - 13,595,685 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013374884 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000022208
  ENSCLAP00000022208.1
RefSeq Acc Id: XP_013374884   ⟸   XM_013519430
- UniProtKB: A0A8C2W5E6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000022208   ⟸   ENSCLAT00000022413
Protein Domains
SH2   SOCS box


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000015232 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000022413 ENTREZGENE
  ENSCLAT00000022413.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.505.10 UniProtKB/TrEMBL
InterPro SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
  SOCS7_SH2 UniProtKB/TrEMBL
  SOCS7_SOCS UniProtKB/TrEMBL
  SOCS_box UniProtKB/TrEMBL
  SOCS_box-like_dom_sf UniProtKB/TrEMBL
NCBI Gene Socs7 ENTREZGENE
PANTHER PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT UniProtKB/TrEMBL
  SUPPRESSOR OF CYTOKINE SIGNALING 7 UniProtKB/TrEMBL
Pfam SH2 UniProtKB/TrEMBL
  SOCS_box UniProtKB/TrEMBL
PROSITE SH2 UniProtKB/TrEMBL
  SOCS UniProtKB/TrEMBL
SMART SH2 UniProtKB/TrEMBL
  SOCS UniProtKB/TrEMBL
  SOCS_box UniProtKB/TrEMBL
Superfamily-SCOP SSF158235 UniProtKB/TrEMBL
  SSF55550 UniProtKB/TrEMBL
UniProt A0A8C2W5E6 ENTREZGENE, UniProtKB/TrEMBL