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ONTOLOGY REPORT - ANNOTATIONS

Term:DNA replication preinitiation complex
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Accession:GO:0031261 term browser browse the term
Definition:A protein-DNA complex assembled at eukaryotic DNA replication origins immediately prior to the initiation of DNA replication. The preinitiation complex is formed by the assembly of additional proteins onto an existing prereplicative complex. In budding yeast, the additional proteins might include Cdc45p, Sld2p, Sld3p, Dpb11p, DNA polymerases, and others; in fission yeast the GINS complex is present.
Synonyms:exact_synonym: pre-IC


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DNA replication preinitiation complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC45 cell division cycle 45 part_of IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr14:51,133,111...51,158,604
Ensembl chr14:51,133,408...51,158,606 		JBrowse link
G ORC3 origin recognition complex subunit 3 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr 1:55,982,132...56,044,244
Ensembl chr 1:55,954,159...56,042,853 		JBrowse link
CMG complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC45 cell division cycle 45 located_in
part_of		 ISO
IEA		 (PMID:22474384) ComplexPortal
Ensembl		 PMID:22474384 GO_REF:0000107 NCBI chr14:51,133,111...51,158,604
Ensembl chr14:51,133,408...51,158,606 		JBrowse link
G GINS1 GINS complex subunit 1 located_in
part_of		 ISO
IEA		 (PMID:22474384) ComplexPortal
Ensembl		 PMID:22474384 GO_REF:0000107 NCBI chr17:31,060,540...31,076,807
Ensembl chr17:31,060,650...31,080,314 		JBrowse link
G GINS2 GINS complex subunit 2 located_in
part_of		 ISO
IEA		 (PMID:22474384) ComplexPortal
Ensembl		 PMID:22474384 GO_REF:0000107 NCBI chr 6:3,218,655...3,252,740
Ensembl chr 6:3,218,702...3,243,899 		JBrowse link
G GINS3 GINS complex subunit 3 located_in
part_of		 ISO
IEA		 (PMID:22474384) ComplexPortal
Ensembl		 PMID:22474384 GO_REF:0000107 NCBI chr 6:20,162,264...20,170,385
Ensembl chr 6:20,162,636...20,170,258 		JBrowse link
G GINS4 GINS complex subunit 4 located_in
part_of		 ISO
IEA		 (PMID:22474384) ComplexPortal
Ensembl		 PMID:22474384 GO_REF:0000107 NCBI chr17:10,656,869...10,668,664
Ensembl chr17:10,656,884...10,668,664 		JBrowse link
G MCM2 minichromosome maintenance complex component 2 located_in
part_of		 ISO
IEA		 (PMID:22474384) ComplexPortal
Ensembl		 PMID:22474384 GO_REF:0000107 NCBI chr13:72,630,378...72,651,270
Ensembl chr13:72,630,380...72,657,786 		JBrowse link
G MCM3 minichromosome maintenance complex component 3 located_in
part_of		 ISO
IEA		 (PMID:22474384) ComplexPortal
Ensembl		 PMID:22474384 GO_REF:0000107 NCBI chr 7:46,084,648...46,104,425
Ensembl chr 7:46,084,662...46,104,375 		JBrowse link
G MCM4 minichromosome maintenance complex component 4 located_in
part_of		 ISO
IEA		 (PMID:22474384) ComplexPortal
Ensembl		 PMID:22474384 GO_REF:0000107 NCBI chr 4:79,674,737...79,686,964
Ensembl chr 4:79,674,739...79,686,685 		JBrowse link
G MCM5 minichromosome maintenance complex component 5 located_in
part_of		 ISO
IEA		 (PMID:22474384) ComplexPortal
Ensembl		 PMID:22474384 GO_REF:0000107
G MCM6 minichromosome maintenance complex component 6 located_in
part_of		 ISO
IEA		 (PMID:22474384) ComplexPortal
Ensembl		 PMID:22474384 GO_REF:0000107 NCBI chr15:15,923,638...15,978,587
Ensembl chr15:15,923,681...15,985,405 		JBrowse link
G MCM7 minichromosome maintenance complex component 7 located_in
part_of		 ISO
IEA		 (PMID:22474384) ComplexPortal
Ensembl		 PMID:22474384 GO_REF:0000107 NCBI chr 3:8,005,890...8,014,047
Ensembl chr 3:8,005,900...8,014,053 		JBrowse link
GINS complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GINS1 GINS complex subunit 1 located_in
part_of		 ISO
IEA
IBA		 (PMID:17417653) ComplexPortal
TreeGrafter
GO_Central
UniProt
InterPro
Ensembl		 PMID:17417653 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr17:31,060,540...31,076,807
Ensembl chr17:31,060,650...31,080,314 		JBrowse link
G GINS2 GINS complex subunit 2 located_in
part_of		 ISO
IBA
IEA		 (PMID:17417653) ComplexPortal
GO_Central
TreeGrafter
Ensembl		 PMID:17417653 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:3,218,655...3,252,740
Ensembl chr 6:3,218,702...3,243,899 		JBrowse link
G GINS3 GINS complex subunit 3 located_in
part_of		 ISO
IEA		 (PMID:17417653) ComplexPortal
TreeGrafter
UniProt
Ensembl		 PMID:17417653 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:20,162,264...20,170,385
Ensembl chr 6:20,162,636...20,170,258 		JBrowse link
G GINS4 GINS complex subunit 4 located_in
part_of		 ISO
IEA
IBA		 (PMID:17417653) ComplexPortal
TreeGrafter
GO_Central
Ensembl		 PMID:17417653 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr17:10,656,869...10,668,664
Ensembl chr17:10,656,884...10,668,664 		JBrowse link
G SLC5A8 solute carrier family 5 member 8 part_of IEA Ensembl GO_REF:0000107 NCBI chr 5:82,973,179...83,088,542
Ensembl chr 5:82,973,284...83,031,157 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 18687
    protein-containing complex 6005
      nuclear protein-containing complex 1244
        DNA replication preinitiation complex 13
          CMG complex 11
          GINS complex 5
Path 2
Term Annotations click to browse term
  cellular_component 18687
    cellular anatomical entity 18466
      organelle 12444
        intracellular organelle 12019
          intracellular membrane-bounded organelle 10861
            nucleus 6843
              nuclear lumen 3884
                nucleoplasm 3447
                  DNA replication preinitiation complex 13
                    CMG complex 11
                    GINS complex 5
paths to the root