ORC3 (origin recognition complex subunit 3) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: ORC3 (origin recognition complex subunit 3) Sus scrofa
Analyze
Symbol: ORC3
Name: origin recognition complex subunit 3
RGD ID: 13987353
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA replication origin binding (inferred); INVOLVED IN glial cell proliferation (ortholog); neural precursor cell proliferation (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN nuclear origin of replication recognition complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl155,954,159 - 56,042,853 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1155,982,132 - 56,044,244 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2162,784,200 - 62,787,566 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ORC3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl155,954,159 - 56,042,853 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1155,982,132 - 56,044,244 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2162,784,200 - 62,787,566 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ORC3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38687,590,135 - 87,677,823 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl687,590,067 - 87,667,453 (+)EnsemblGRCh38hg38GRCh38
GRCh37688,299,853 - 88,377,169 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36688,356,562 - 88,433,888 (+)NCBINCBI36Build 36hg18NCBI36
Build 34688,356,561 - 88,433,885NCBI
Celera688,718,203 - 88,795,190 (+)NCBICelera
Cytogenetic Map6q15NCBI
HuRef685,515,390 - 85,592,365 (+)NCBIHuRef
CHM1_1688,397,143 - 88,474,506 (+)NCBICHM1_1
T2T-CHM13v2.0688,798,431 - 88,886,160 (+)NCBIT2T-CHM13v2.0
Orc3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39434,566,781 - 34,614,942 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl434,570,796 - 34,614,944 (-)EnsemblGRCm39 Ensembl
GRCm38434,566,781 - 34,614,963 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl434,570,796 - 34,614,944 (-)EnsemblGRCm38mm10GRCm38
MGSCv37434,514,030 - 34,562,191 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36434,758,190 - 34,803,831 (-)NCBIMGSCv36mm8
Celera434,296,360 - 34,344,495 (-)NCBICelera
Cytogenetic Map4A5NCBI
cM Map416.81NCBI
Orc3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8553,923,264 - 53,977,869 (-)NCBIGRCr8
mRatBN7.2549,123,758 - 49,181,552 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl549,126,955 - 49,181,633 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx551,320,134 - 51,374,803 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0552,920,367 - 52,975,034 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0552,826,274 - 52,880,639 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0550,019,159 - 50,075,533 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl550,020,815 - 50,075,454 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0554,588,113 - 54,644,440 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4551,172,243 - 51,226,644 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1551,172,422 - 51,226,823 (-)NCBI
Celera547,877,684 - 47,931,950 (-)NCBICelera
Cytogenetic Map5q21NCBI
Orc3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541114,528,043 - 14,595,616 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541114,527,987 - 14,595,216 (+)NCBIChiLan1.0ChiLan1.0
ORC3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25107,671,472 - 107,757,550 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16105,565,286 - 105,651,326 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0685,466,928 - 85,552,619 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1688,741,362 - 88,816,434 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl688,741,362 - 88,829,801 (+)Ensemblpanpan1.1panPan2
ORC3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11247,047,341 - 47,108,126 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1247,047,195 - 47,108,117 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1246,855,302 - 46,915,592 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01247,853,551 - 47,913,880 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1247,853,396 - 47,913,878 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11247,145,146 - 47,206,401 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01247,072,621 - 47,133,465 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01247,261,944 - 47,323,195 (+)NCBIUU_Cfam_GSD_1.0
Orc3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494682,189,035 - 82,256,122 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365104,225,697 - 4,282,190 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365104,222,036 - 4,281,800 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ORC3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11312,068,167 - 12,159,079 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1312,068,235 - 12,159,401 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040188,322,311 - 188,395,205 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Orc3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247996,649,634 - 6,729,604 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247996,649,034 - 6,728,933 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ORC3
1057 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 3 2 3 5 16 2 3 1
Low 7 2 2 7 2
Below cutoff

Sequence


RefSeq Acc Id: ENSSSCT00000004761   ⟹   ENSSSCP00000004650
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl155,982,175 - 56,042,895 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000037698   ⟹   ENSSSCP00000058251
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl155,954,159 - 56,042,853 (+)Ensembl
RefSeq Acc Id: XM_003121290   ⟹   XP_003121338
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1155,982,132 - 56,044,242 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021089812   ⟹   XP_020945471
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1155,982,132 - 56,044,244 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021089821   ⟹   XP_020945480
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1155,982,162 - 56,044,242 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021089832   ⟹   XP_020945491
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1155,982,162 - 56,044,242 (+)NCBI
Sequence:
RefSeq Acc Id: XP_020945471   ⟸   XM_021089812
- Peptide Label: isoform X2
- UniProtKB: A0A480KMI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003121338   ⟸   XM_003121290
- Peptide Label: isoform X1
- UniProtKB: A0A287BP12 (UniProtKB/TrEMBL),   A0A8D2CCN4 (UniProtKB/TrEMBL),   A0A8D0IA54 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020945491   ⟸   XM_021089832
- Peptide Label: isoform X3
- UniProtKB: A0A480Y1T4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020945480   ⟸   XM_021089821
- Peptide Label: isoform X3
- UniProtKB: A0A480Y1T4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000058251   ⟸   ENSSSCT00000037698
RefSeq Acc Id: ENSSSCP00000004650   ⟸   ENSSSCT00000004761

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000004306 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005008031 UniProtKB/TrEMBL
  ENSSSCG00050069834 UniProtKB/TrEMBL
  ENSSSCG00060052574 UniProtKB/TrEMBL
  ENSSSCG00065059553 UniProtKB/TrEMBL
  ENSSSCG00070024715 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000037698 ENTREZGENE
  ENSSSCT00000037698.2 UniProtKB/TrEMBL
  ENSSSCT00005012128.1 UniProtKB/TrEMBL
  ENSSSCT00050095246.1 UniProtKB/TrEMBL
  ENSSSCT00060071605.1 UniProtKB/TrEMBL
  ENSSSCT00065081552.1 UniProtKB/TrEMBL
  ENSSSCT00070049334.1 UniProtKB/TrEMBL
  ENSSSCT00070049336.1 UniProtKB/TrEMBL
InterPro ORC3 UniProtKB/TrEMBL
  ORC3_ins UniProtKB/TrEMBL
  ORC3_N UniProtKB/TrEMBL
  ORC_WH_C UniProtKB/TrEMBL
NCBI Gene ORC3 ENTREZGENE
PANTHER ORIGIN RECOGNITION COMPLEX SUBUNIT 3 UniProtKB/TrEMBL
  PTHR12748 UniProtKB/TrEMBL
Pfam ORC3_ins UniProtKB/TrEMBL
  ORC3_N UniProtKB/TrEMBL
  ORC_WH_C UniProtKB/TrEMBL
UniProt A0A287BP12 ENTREZGENE, UniProtKB/TrEMBL
  A0A480KMI1 ENTREZGENE, UniProtKB/TrEMBL
  A0A480Y1T4 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1VEF6_PIG UniProtKB/TrEMBL
  A0A4X1VIM7_PIG UniProtKB/TrEMBL
  A0A8D0IA54 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D2CCN4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:91061 ENTREZGENE