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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:cyclooxygenase pathway
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Accession:GO:0019371 term browser browse the term
Definition:The chemical reactions and pathways by which prostaglandins are formed from arachidonic acid, and in which prostaglandin-endoperoxide synthase (cyclooxygenase) catalyzes the committed step in the conversion of arachidonic acid to the prostaglandin-endoperoxides PGG2 and PGH2.


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cyclooxygenase pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb1 bradykinin receptor B1 involved_in ISO (PMID:23846981) RGD PMID:23846981 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 involved_in IEA
ISO
IBA		 GO_REF:0000107
(PMID:1380156)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:1380156 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 involved_in
acts_upstream_of_or_within		 ISS
ISO
IBA		 GO_REF:0000024
(PMID:1380156), (PMID:7592599), (PMID:7947975)
(MGI:5315361|PMID:12925531)
GO_REF:0000033
(PMID:1419907)		 UniProt
RGD
GO_Central		 PMID:1380156 PMID:1419907 PMID:7592599 PMID:7947975 PMID:12925531 GO_REF:0000024 GO_REF:0000033 MGI:5315361 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Sco1 synthesis of cytochrome C oxidase 1 acts_upstream_of_or_within ISO MGI:2182095|MGI:5758867 (PMID:28973536) RGD PMID:28973536 NCBI chr10:51,744,656...51,757,246
Ensembl chr10:51,744,656...51,757,237 		JBrowse link
G Sphk1 sphingosine kinase 1 IDA RGD PMID:18723875 RGD:2311353 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    metabolic process 11456
      organic substance metabolic process 10970
        olefinic compound metabolic process 181
          arachidonic acid metabolic process 70
            cyclooxygenase pathway 5
Path 2
Term Annotations click to browse term
  biological_process 19692
    metabolic process 11456
      cellular metabolic process 9554
        organic acid metabolic process 1021
          oxoacid metabolic process 1010
            carboxylic acid metabolic process 995
              monocarboxylic acid metabolic process 729
                fatty acid metabolic process 454
                  unsaturated fatty acid metabolic process 142
                    prostanoid metabolic process 61
                      prostaglandin metabolic process 60
                        prostaglandin biosynthetic process 37
                          cyclooxygenase pathway 5
paths to the root