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ONTOLOGY REPORT - ANNOTATIONS


Term:prostanoid metabolic process
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Accession:GO:0006692 term browser browse the term
Definition:The chemical reactions and pathways involving prostanoids, any compound based on or derived from the prostanoate structure.
Synonyms:exact_synonym: prostanoid metabolism


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cyclooxygenase pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bdkrb1 bradykinin receptor B1 JBrowse link 6 129,437,423 129,441,553 RGD:1624291
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:1624291
RGD:1600115
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:1600115
RGD:1624291
G Sphk1 sphingosine kinase 1 JBrowse link 10 105,498,728 105,504,401 RGD:2311353
negative regulation of prostaglandin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pibf1 progesterone immunomodulatory binding factor 1 JBrowse link 15 83,494,110 83,663,202 RGD:1624291
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
positive regulation of prostaglandin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa1 annexin A1 JBrowse link 1 237,893,983 237,910,002 RGD:2306959
RGD:13792537
G Avp arginine vasopressin JBrowse link 3 123,117,482 123,119,460 RGD:2300349
G Avpr1a arginine vasopressin receptor 1A JBrowse link 7 67,341,366 67,345,290 RGD:2300349
G Cd74 CD74 molecule JBrowse link 18 56,071,420 56,080,851 RGD:1624291
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1600115
RGD:1624291
G Mapk9 mitogen-activated protein kinase 9 JBrowse link 10 35,333,859 35,374,364 RGD:2304243
G Pla2g3 phospholipase A2, group III JBrowse link 14 83,724,828 83,730,614 RGD:1624291
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:1642461
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:1624291
prostaglandin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07034131.1 RGD:13792537
G AABR07054614.1 RGD:1600115
RGD:13792537
G Cd74 CD74 molecule JBrowse link 18 56,071,420 56,080,851 RGD:1624291
RGD:1600115
G Daglb diacylglycerol lipase, beta JBrowse link 12 13,113,073 13,157,748 RGD:1600115
RGD:1624291
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:1624291
G Edn2 endothelin 2 JBrowse link 5 139,098,472 139,106,396 RGD:1624291
RGD:1600115
G Hpgds hematopoietic prostaglandin D synthase JBrowse link 4 95,945,356 95,970,666 RGD:68838
G Mif macrophage migration inhibitory factor JBrowse link 20 13,715,219 13,732,980 RGD:1624291
G Pla2g10 phospholipase A2, group X JBrowse link 10 1,509,732 1,520,970 RGD:1624291
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:1624291
RGD:1600115
G Pla2g4f phospholipase A2, group IVF JBrowse link 3 112,068,617 112,083,978 RGD:1624291
G Pnpla8 patatin-like phospholipase domain containing 8 JBrowse link 6 64,224,870 64,288,465 RGD:1624291
G Prxl2b peroxiredoxin like 2B JBrowse link 5 172,304,799 172,307,402 RGD:1624291
RGD:8552775
RGD:1600115
G Ptgds prostaglandin D2 synthase JBrowse link 3 2,686,125 2,689,059 RGD:8553429
RGD:1624291
G Ptges prostaglandin E synthase JBrowse link 3 9,727,408 9,738,752 RGD:67929
RGD:13792537
RGD:1624291
G Ptges3 prostaglandin E synthase 3 JBrowse link 7 2,479,267 2,497,024 RGD:5688071
RGD:13792537
RGD:1600115
RGD:1624291
G Ptges3l1 prostaglandin E synthase 3-like 1 JBrowse link X 45,410,545 45,419,817 RGD:13792537
G Ptgis prostaglandin I2 synthase JBrowse link 3 163,950,746 163,986,129 RGD:727270
RGD:13792537
RGD:1624291
RGD:1600115
RGD:8693629
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:2300259
RGD:1600115
RGD:1624291
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:2300259
RGD:1624291
G Tbxas1 thromboxane A synthase 1 JBrowse link 4 66,624,181 66,846,745 RGD:1624291
prostaglandin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abhd16a abhydrolase domain containing 16A, phospholipase JBrowse link 20 5,080,070 5,094,935 RGD:1624291
RGD:1600115
G Cbr1 carbonyl reductase 1 JBrowse link 11 33,813,041 33,815,418 RGD:69801
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 JBrowse link 7 14,891,062 14,907,250 RGD:15090848
G Lypla2 lysophospholipase 2 JBrowse link 5 154,315,033 154,319,629 RGD:1624291
RGD:1600115
prostaglandin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acox1 acyl-CoA oxidase 1 JBrowse link 10 104,724,534 104,748,003 RGD:1600115
RGD:1624291
G Akr1c1 aldo-keto reductase family 1, member C1 JBrowse link 17 69,441,253 69,460,334 RGD:13792537
G Akr1c14 aldo-keto reductase family 1, member C14 JBrowse link 17 69,806,095 69,827,125 RGD:13792537
G Akr1c2 aldo-keto reductase family 1, member C2 JBrowse link 17 69,388,337 69,435,160 RGD:1624291
RGD:13792537
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:1624291
RGD:13792537
G Atp6v1b1 ATPase H+ transporting V1 subunit B1 JBrowse link 4 115,417,100 115,435,754 RGD:1624291
G Ces2h carboxylesterase 2H JBrowse link 19 37,052,555 37,067,176 RGD:1624291
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 JBrowse link 1 82,595,211 82,610,350 RGD:1624291
G Gsta1 glutathione S-transferase alpha 1 JBrowse link 9 27,366,404 27,381,004 RGD:1624291
G Gsta2 glutathione S-transferase alpha 2 JBrowse link 8 85,640,081 85,645,621 RGD:1600115
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:1600115
RGD:1624291
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:1600115
RGD:1624291
G Hpgd 15-hydroxyprostaglandin dehydrogenase JBrowse link 16 37,457,134 37,495,758 RGD:11667092
RGD:1624291
RGD:13792537
RGD:1600115
G Hpgds hematopoietic prostaglandin D synthase JBrowse link 4 95,945,356 95,970,666 RGD:1624291
RGD:1600115
G Pdpn podoplanin JBrowse link 5 161,947,137 161,981,441 RGD:1624291
G Plaa phospholipase A2, activating protein JBrowse link 5 113,548,913 113,578,928 RGD:1624291
RGD:1600115
G Ptges prostaglandin E synthase JBrowse link 3 9,727,408 9,738,752 RGD:1624291
G Ptges3 prostaglandin E synthase 3 JBrowse link 7 2,479,267 2,497,024 RGD:5688070
G Ptgr1 prostaglandin reductase 1 JBrowse link 5 76,110,746 76,129,361 RGD:13792537
G Ptgr2 prostaglandin reductase 2 JBrowse link 6 107,999,832 108,031,645 RGD:1624291
RGD:13792537
RGD:1600115
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:1624291
G RGD1564865 similar to 20-alpha-hydroxysteroid dehydrogenase JBrowse link 17 69,468,427 69,497,132 RGD:13792537
G Tnfrsf1a TNF receptor superfamily member 1A JBrowse link 4 157,864,905 157,877,634 RGD:1600115
G Zadh2 zinc binding alcohol dehydrogenase, domain containing 2 JBrowse link 18 80,939,875 80,949,226 RGD:1600115
regulation of prostaglandin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fabp5 fatty acid binding protein 5 JBrowse link 2 93,981,662 93,985,322 RGD:1624291
regulation of prostaglandin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hpgd 15-hydroxyprostaglandin dehydrogenase JBrowse link 16 37,457,134 37,495,758 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12097
      organic substance metabolic process 11495
        fatty acid derivative metabolic process 169
          icosanoid metabolic process 136
            prostanoid metabolic process 56
              prostaglandin metabolic process + 56
              prostanoid biosynthetic process + 32
              prostanoid catabolic process + 5
Path 2
Term Annotations click to browse term
  biological_process 19858
    cellular process 18618
      cellular metabolic process 10918
        organic acid metabolic process 1073
          oxoacid metabolic process 1046
            carboxylic acid metabolic process 998
              monocarboxylic acid metabolic process 656
                fatty acid metabolic process 417
                  unsaturated fatty acid metabolic process 135
                    prostanoid metabolic process 56
                      prostaglandin metabolic process + 56
                      prostanoid biosynthetic process + 32
                      prostanoid catabolic process + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.