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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of eIF2 alpha phosphorylation by heme
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Accession:GO:0010999 term browser browse the term
Definition:Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a result of heme levels.
Synonyms:xref: Reactome:R-HSA-9648895 "Response of EIF2AK1 (HRI) to heme deficiency"



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regulation of eIF2 alpha phosphorylation by heme term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 acts_upstream_of_or_within ISO MGI:1353448|MGI:95513 (PMID:15931390) RGD PMID:15931390 NCBI chr12:10,710,771...10,744,597 JBrowse link
G Fech ferrochelatase acts_upstream_of_or_within ISO MGI:1353448|MGI:1858114|MGI:95513 (PMID:15931390) RGD PMID:15931390 NCBI chr18:57,945,123...57,978,327 JBrowse link
G Hbb hemoglobin subunit beta acts_upstream_of_or_within ISO MGI:1857179 (PMID:15931390) RGD PMID:15931390 NCBI chr 1:158,250,421...158,251,832 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    cellular process 19525
      regulation of cellular process 13014
        regulation of cellular response to stress 517
          regulation of eIF2 alpha phosphorylation by heme 3
Path 2
Term Annotations click to browse term
  biological_process 20536
    biological regulation 13822
      regulation of biological process 13376
        regulation of cellular process 13014
          regulation of metabolic process 6834
            regulation of biosynthetic process 5630
              regulation of macromolecule biosynthetic process 5425
                regulation of gene expression 5308
                  post-transcriptional regulation of gene expression 762
                    regulation of translation 481
                      regulation of translational initiation 74
                        regulation of translational initiation in response to stress 14
                          regulation of translational initiation by eIF2 alpha phosphorylation 11
                            regulation of eIF2 alpha phosphorylation by heme 3
paths to the root