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ONTOLOGY REPORT - ANNOTATIONS

Term:L-tryptophan catabolic process
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Accession:GO:0006569 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of L-tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
Synonyms:exact_synonym: tryptophan breakdown;   tryptophan catabolism;   tryptophan degradation
 narrow_synonym: tryptophan catabolic process, using tryptophanase;   tryptophan catabolism, using tryptophanase
 related_synonym: tryptophan catabolic process
 xref: Reactome:R-HSA-71240 "Tryptophan catabolism"


show annotations for term's descendants           Sort by:
L-tryptophan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACMSD aminocarboxymuconate semialdehyde decarboxylase ISO RGD PMID:11802786 RGD:70243 NCBI chr19:37,658,999...37,725,426
Ensembl chr19:37,659,226...37,725,172 		JBrowse link
G AFMID arylformamidase involved_in IEA UniProt GO_REF:0000043
G HAAO 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA UniProt GO_REF:0000104 NCBI chr10:45,368,157...45,379,521
Ensembl chr10:45,368,178...45,379,160 		JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 involved_in IEA UniProt GO_REF:0000043 GO_REF:0000117 NCBI chr16:25,391,759...25,407,161
Ensembl chr16:25,391,754...25,407,048 		JBrowse link
G IDO2 indoleamine 2,3-dioxygenase 2 involved_in IEA UniProt GO_REF:0000043 GO_REF:0000117 NCBI chr16:25,319,035...25,375,085
Ensembl chr16:25,319,035...25,385,515 		JBrowse link
G IL4I1 interleukin 4 induced 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:106,636,282...106,673,438
Ensembl chr 1:106,657,477...106,673,422 		JBrowse link
G KMO kynurenine 3-monooxygenase involved_in IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000104 NCBI chr 7:32,941,487...32,994,541
Ensembl chr 7:32,941,487...32,994,541 		JBrowse link
G KYNU kynureninase involved_in IEA InterPro
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 NCBI chr19:45,022,450...45,150,977
Ensembl chr19:45,022,072...45,149,339 		JBrowse link
G TDO2 tryptophan 2,3-dioxygenase involved_in IEA UniProt GO_REF:0000043 GO_REF:0000117 NCBI chr15:53,406,110...53,424,260
Ensembl chr15:53,405,957...53,423,958 		JBrowse link
L-tryptophan catabolic process to acetyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KYNU kynureninase ISO RGD PMID:7236232 RGD:2303721 NCBI chr19:45,022,450...45,150,977
Ensembl chr19:45,022,072...45,149,339 		JBrowse link
G TDO2 tryptophan 2,3-dioxygenase involved_in ISO
IBA		 RGD
GO_Central		 PMID:7236232 GO_REF:0000033 RGD:2303721 NCBI chr15:53,406,110...53,424,260
Ensembl chr15:53,405,957...53,423,958 		JBrowse link
L-tryptophan catabolic process to indole-3-acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL4I1 interleukin 4 induced 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:106,636,282...106,673,438
Ensembl chr 1:106,657,477...106,673,422 		JBrowse link
L-tryptophan catabolic process to kynurenine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AFMID arylformamidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15866519) InterPro
UniProt
MGI		 PMID:15866519 GO_REF:0000002 GO_REF:0000041 GO_REF:0000104
G IDO1 indoleamine 2,3-dioxygenase 1 involved_in
acts_upstream_of_or_within		 ISO
IEA
IBA		 (PMID:11751753), (PMID:2419335) RGD
InterPro
MGI
UniProt
GO_Central		 PMID:2419335 PMID:10719243 PMID:11513477 PMID:11751753 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 RGD:2290190 RGD:2290543 NCBI chr16:25,391,759...25,407,161
Ensembl chr16:25,391,754...25,407,048 		JBrowse link
G IDO2 indoleamine 2,3-dioxygenase 2 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 (PMID:17499941)
(PMID:17671174)		 InterPro
GO_Central
UniProt
MGI
Ensembl		 PMID:17499941 PMID:17671174 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 NCBI chr16:25,319,035...25,375,085
Ensembl chr16:25,319,035...25,385,515 		JBrowse link
G KYNU kynureninase involved_in IBA GO_Central GO_REF:0000033 NCBI chr19:45,022,450...45,150,977
Ensembl chr19:45,022,072...45,149,339 		JBrowse link
G TDO2 tryptophan 2,3-dioxygenase involved_in IEA InterPro
UniProt
Ensembl		 GO_REF:0000002 GO_REF:0000041 GO_REF:0000104 GO_REF:0000107 NCBI chr15:53,406,110...53,424,260
Ensembl chr15:53,405,957...53,423,958 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22099
    cellular process 21628
      metabolic process 15370
        indole-containing compound metabolic process 28
          indole-containing compound catabolic process 9
            L-tryptophan catabolic process 9
              L-tryptophan catabolic process to acetyl-CoA 2
              L-tryptophan catabolic process to indole-3-acetate 1
              L-tryptophan catabolic process to kynurenine 5
Path 2
Term Annotations click to browse term
  biological_process 22099
    cellular process 21628
      metabolic process 15370
        small molecule metabolic process 1808
          organic acid metabolic process 971
            oxoacid metabolic process 958
              carboxylic acid metabolic process 943
                alpha-amino acid metabolic process 213
                  alpha-amino acid catabolic process 95
                    L-amino acid catabolic process 76
                      erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process 17
                        L-tryptophan catabolic process 9
                          L-tryptophan catabolic process to acetyl-CoA 2
                          L-tryptophan catabolic process to indole-3-acetate 1
                          L-tryptophan catabolic process to kynurenine 5
paths to the root