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ONTOLOGY REPORT - ANNOTATIONS

Term:isoleucyl-tRNA aminoacylation
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Accession:GO:0006428 term browser browse the term
Definition:The process of coupling isoleucine to isoleucyl-tRNA, catalyzed by isoleucyl-tRNA synthetase. The isoleucyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a isoleucine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.


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isoleucyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IARS1 isoleucyl-tRNA synthetase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA
IBA		 (PMID:8052601) MGI
InterPro
Ensembl
GO_Central		 PMID:8052601 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:99,045,023...99,113,865
Ensembl chr 1:99,045,102...99,113,620 		JBrowse link
G IARS2 isoleucyl-tRNA synthetase 2, mitochondrial involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr38:14,864,004...14,925,684
Ensembl chr38:14,863,998...14,925,635 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22099
    cellular process 21628
      metabolic process 15370
        biosynthetic process 12079
          macromolecule biosynthetic process 11135
            translation 941
              tRNA aminoacylation for protein translation 43
                isoleucyl-tRNA aminoacylation 2
                  mitochondrial isoleucyl-tRNA aminoacylation 0
Path 2
Term Annotations click to browse term
  biological_process 22099
    cellular process 21628
      metabolic process 15370
        primary metabolic process 13969
          nucleobase-containing compound metabolic process 9612
            nucleic acid metabolic process 9019
              RNA metabolic process 8458
                tRNA metabolic process 201
                  tRNA aminoacylation 46
                    tRNA aminoacylation for protein translation 43
                      isoleucyl-tRNA aminoacylation 2
                        mitochondrial isoleucyl-tRNA aminoacylation 0
paths to the root