IARS1 (isoleucyl-tRNA synthetase 1) - Rat Genome Database

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Gene: IARS1 (isoleucyl-tRNA synthetase 1) Canis lupus familiaris
Analyze
Symbol: IARS1
Name: isoleucyl-tRNA synthetase 1
RGD ID: 12366613
Description: ENCODES a protein that exhibits aminoacyl-tRNA editing activity (inferred); aminoacyl-tRNA ligase activity (inferred); ATP binding (inferred); INVOLVED IN isoleucyl-tRNA aminoacylation (ortholog); ASSOCIATED WITH Developmental Disabilities (ortholog); genetic disease (ortholog); GROWTH RETARDATION, INTELLECTUAL DEVELOPMENTAL DISORDER, HYPOTONIA, AND HEPATOPATHY (ortholog); FOUND IN aminoacyl-tRNA synthetase multienzyme complex (inferred); cytoplasm (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: IARS; isoleucine--tRNA ligase, cytoplasmic; isoleucyl-tRNA synthetase; isoleucyl-tRNA synthetase, cytoplasmic
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1199,045,023 - 99,113,865 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl199,045,102 - 99,113,620 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha199,438,844 - 99,507,644 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0199,662,000 - 99,730,810 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl199,662,052 - 99,730,810 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1199,274,953 - 99,343,693 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0199,010,147 - 99,079,155 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0199,766,929 - 99,835,896 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
IARS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1199,045,023 - 99,113,865 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl199,045,102 - 99,113,620 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha199,438,844 - 99,507,644 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0199,662,000 - 99,730,810 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl199,662,052 - 99,730,810 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1199,274,953 - 99,343,693 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0199,010,147 - 99,079,155 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0199,766,929 - 99,835,896 (+)NCBIUU_Cfam_GSD_1.0
IARS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38992,210,207 - 92,293,697 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl992,210,207 - 92,293,854 (-)EnsemblGRCh38hg38GRCh38
GRCh37994,972,489 - 95,055,979 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36994,012,446 - 94,095,859 (-)NCBINCBI36Build 36hg18NCBI36
Build 34992,052,179 - 92,135,522NCBI
Celera965,408,928 - 65,492,347 (-)NCBICelera
Cytogenetic Map9q22.31NCBI
HuRef964,650,352 - 64,733,811 (-)NCBIHuRef
CHM1_1995,118,853 - 95,202,471 (-)NCBICHM1_1
T2T-CHM13v2.09104,376,735 - 104,460,226 (-)NCBIT2T-CHM13v2.0
Iars1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391349,835,606 - 49,887,743 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1349,835,576 - 49,887,743 (+)EnsemblGRCm39 Ensembl
GRCm381349,682,130 - 49,734,267 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1349,682,100 - 49,734,267 (+)EnsemblGRCm38mm10GRCm38
MGSCv371349,777,499 - 49,829,636 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361349,694,081 - 49,746,194 (+)NCBIMGSCv36mm8
Celera1350,772,786 - 50,823,970 (+)NCBICelera
Cytogenetic Map13A5NCBI
cM Map1325.38NCBI
Iars1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81715,147,357 - 15,193,716 (-)NCBIGRCr8
mRatBN7.21714,940,919 - 14,987,277 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1714,940,924 - 14,987,237 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1714,827,845 - 14,874,168 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01716,432,900 - 16,479,224 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01714,754,642 - 14,800,962 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01715,356,016 - 15,402,680 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1715,355,529 - 15,402,649 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01717,414,466 - 17,461,119 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01716,604,188 - 16,614,960 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41720,895,852 - 20,942,180 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11720,895,861 - 20,937,378 (-)NCBI
Celera1714,672,657 - 14,718,804 (-)NCBICelera
Cytogenetic Map17p14NCBI
Iars1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555155,498,231 - 5,557,629 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555155,506,064 - 5,558,075 (+)NCBIChiLan1.0ChiLan1.0
IARS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21147,136,048 - 47,219,577 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1947,138,434 - 47,221,967 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0963,332,030 - 63,415,567 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1991,406,008 - 91,489,167 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl991,406,008 - 91,489,167 (-)Ensemblpanpan1.1panPan2
Iars1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049447,672,824 - 7,732,017 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364871,886,552 - 1,948,498 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364871,889,428 - 1,948,447 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IARS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl341,945,770 - 42,022,760 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1341,945,846 - 42,022,610 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2342,962,905 - 43,014,138 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IARS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112102,745,155 - 102,819,638 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl12102,744,569 - 102,819,603 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603891,017,103 - 91,091,888 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Iars1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248684,063,002 - 4,168,715 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248684,062,938 - 4,168,712 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in IARS1
621 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 14 6 6 6 12 6 10 6
Low 8 6 6 2
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_014118130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022422371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038466673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038466674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038466675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038466676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038527394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038527395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038527396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038527397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038591693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038591694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038591695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038591696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038612048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038655487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038655488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038655489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038655490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_541332 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000003663   ⟹   ENSCAFP00000003387
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl199,045,102 - 99,113,620 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000080250   ⟹   ENSCAFP00000049940
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl199,045,102 - 99,113,620 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845000164   ⟹   ENSCAFP00845000126
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl199,662,052 - 99,725,666 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845000170   ⟹   ENSCAFP00845000131
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl199,662,061 - 99,730,810 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845000175   ⟹   ENSCAFP00845000134
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl199,662,061 - 99,730,810 (+)Ensembl
RefSeq Acc Id: XM_014118130   ⟹   XP_013973605
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1199,045,813 - 99,113,865 (+)NCBI
Dog10K_Boxer_Tasha199,439,611 - 99,507,256 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022422371   ⟹   XP_022278079
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1199,045,048 - 99,113,865 (+)NCBI
Dog10K_Boxer_Tasha199,438,844 - 99,507,644 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038466673   ⟹   XP_038322601
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1199,280,910 - 99,343,693 (+)NCBI
RefSeq Acc Id: XM_038466674   ⟹   XP_038322602
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1199,274,953 - 99,343,305 (+)NCBI
RefSeq Acc Id: XM_038466675   ⟹   XP_038322603
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1199,275,721 - 99,343,305 (+)NCBI
RefSeq Acc Id: XM_038466676   ⟹   XP_038322604
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1199,274,953 - 99,343,693 (+)NCBI
RefSeq Acc Id: XM_038527394   ⟹   XP_038383322
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0199,772,883 - 99,835,896 (+)NCBI
RefSeq Acc Id: XM_038527395   ⟹   XP_038383323
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0199,766,929 - 99,835,508 (+)NCBI
RefSeq Acc Id: XM_038527396   ⟹   XP_038383324
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0199,767,697 - 99,835,508 (+)NCBI
RefSeq Acc Id: XM_038527397   ⟹   XP_038383325
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0199,766,929 - 99,835,896 (+)NCBI
RefSeq Acc Id: XM_038591693   ⟹   XP_038447621
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0199,016,303 - 99,079,155 (+)NCBI
RefSeq Acc Id: XM_038591694   ⟹   XP_038447622
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0199,010,147 - 99,078,767 (+)NCBI
RefSeq Acc Id: XM_038591695   ⟹   XP_038447623
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0199,010,914 - 99,078,767 (+)NCBI
RefSeq Acc Id: XM_038591696   ⟹   XP_038447624
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0199,010,147 - 99,079,155 (+)NCBI
RefSeq Acc Id: XM_038612048   ⟹   XP_038467976
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha199,444,801 - 99,507,644 (+)NCBI
RefSeq Acc Id: XM_038655487   ⟹   XP_038511415
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0199,667,958 - 99,730,810 (+)NCBI
RefSeq Acc Id: XM_038655488   ⟹   XP_038511416
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0199,662,000 - 99,730,422 (+)NCBI
RefSeq Acc Id: XM_038655489   ⟹   XP_038511417
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0199,662,767 - 99,730,422 (+)NCBI
RefSeq Acc Id: XM_038655490   ⟹   XP_038511418
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0199,662,000 - 99,730,810 (+)NCBI
RefSeq Acc Id: XM_541332   ⟹   XP_541332
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1199,045,023 - 99,113,865 (+)NCBI
Dog10K_Boxer_Tasha199,438,844 - 99,507,256 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013973605 (Get FASTA)   NCBI Sequence Viewer  
  XP_022278079 (Get FASTA)   NCBI Sequence Viewer  
  XP_038322601 (Get FASTA)   NCBI Sequence Viewer  
  XP_038322602 (Get FASTA)   NCBI Sequence Viewer  
  XP_038322603 (Get FASTA)   NCBI Sequence Viewer  
  XP_038322604 (Get FASTA)   NCBI Sequence Viewer  
  XP_038383322 (Get FASTA)   NCBI Sequence Viewer  
  XP_038383323 (Get FASTA)   NCBI Sequence Viewer  
  XP_038383324 (Get FASTA)   NCBI Sequence Viewer  
  XP_038383325 (Get FASTA)   NCBI Sequence Viewer  
  XP_038447621 (Get FASTA)   NCBI Sequence Viewer  
  XP_038447622 (Get FASTA)   NCBI Sequence Viewer  
  XP_038447623 (Get FASTA)   NCBI Sequence Viewer  
  XP_038447624 (Get FASTA)   NCBI Sequence Viewer  
  XP_038467976 (Get FASTA)   NCBI Sequence Viewer  
  XP_038511415 (Get FASTA)   NCBI Sequence Viewer  
  XP_038511416 (Get FASTA)   NCBI Sequence Viewer  
  XP_038511417 (Get FASTA)   NCBI Sequence Viewer  
  XP_038511418 (Get FASTA)   NCBI Sequence Viewer  
  XP_541332 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000003387.3
  ENSCAFP00000049940.1
  ENSCAFP00000071140.1
  ENSCAFP00000073731.1
  ENSCAFP00030001605.1
  ENSCAFP00030001674.1
  ENSCAFP00030001749.1
  ENSCAFP00040003162.1
  ENSCAFP00040003225.1
  ENSCAFP00040003269.1
  ENSCAFP00040003309.1
  ENSCAFP00040003358.1
  ENSCAFP00845000126.1
  ENSCAFP00845000131
  ENSCAFP00845000131.1
  ENSCAFP00845000134
  ENSCAFP00845000134.1
Reference Protein Sequences
RefSeq Acc Id: XP_541332   ⟸   XM_541332
- Peptide Label: isoform X1
- UniProtKB: A0A8C0M0E3 (UniProtKB/TrEMBL),   A0A8C0KL72 (UniProtKB/TrEMBL),   A0A8I3M9Y6 (UniProtKB/TrEMBL),   A0A8C0PSF6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013973605   ⟸   XM_014118130
- Peptide Label: isoform X1
- UniProtKB: A0A8C0M0E3 (UniProtKB/TrEMBL),   A0A8C0KL72 (UniProtKB/TrEMBL),   A0A8I3M9Y6 (UniProtKB/TrEMBL),   A0A8C0PSF6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022278079   ⟸   XM_022422371
- Peptide Label: isoform X2
- UniProtKB: A0A8C0PSR6 (UniProtKB/TrEMBL),   A0A8I3MFF7 (UniProtKB/TrEMBL),   A0A8C0PSF6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000049940   ⟸   ENSCAFT00000080250
RefSeq Acc Id: ENSCAFP00000003387   ⟸   ENSCAFT00000003663
RefSeq Acc Id: XP_038322604   ⟸   XM_038466676
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038322602   ⟸   XM_038466674
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038322603   ⟸   XM_038466675
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038322601   ⟸   XM_038466673
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038447624   ⟸   XM_038591696
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038447622   ⟸   XM_038591694
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038447623   ⟸   XM_038591695
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038447621   ⟸   XM_038591693
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038511418   ⟸   XM_038655490
- Peptide Label: isoform X2
- UniProtKB: A0A8C0PSR6 (UniProtKB/TrEMBL),   A0A8I3MFF7 (UniProtKB/TrEMBL),   A0A8C0PSF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038511416   ⟸   XM_038655488
- Peptide Label: isoform X1
- UniProtKB: A0A8C0M0E3 (UniProtKB/TrEMBL),   A0A8C0KL72 (UniProtKB/TrEMBL),   A0A8I3M9Y6 (UniProtKB/TrEMBL),   A0A8C0PSF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038511417   ⟸   XM_038655489
- Peptide Label: isoform X1
- UniProtKB: A0A8C0M0E3 (UniProtKB/TrEMBL),   A0A8C0KL72 (UniProtKB/TrEMBL),   A0A8I3M9Y6 (UniProtKB/TrEMBL),   A0A8C0PSF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038511415   ⟸   XM_038655487
- Peptide Label: isoform X1
- UniProtKB: A0A8C0M0E3 (UniProtKB/TrEMBL),   A0A8C0KL72 (UniProtKB/TrEMBL),   A0A8I3M9Y6 (UniProtKB/TrEMBL),   A0A8C0PSF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038467976   ⟸   XM_038612048
- Peptide Label: isoform X1
- UniProtKB: A0A8C0M0E3 (UniProtKB/TrEMBL),   A0A8C0KL72 (UniProtKB/TrEMBL),   A0A8I3M9Y6 (UniProtKB/TrEMBL),   A0A8C0PSF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038383325   ⟸   XM_038527397
- Peptide Label: isoform X2
- UniProtKB: A0A8C0PSF6 (UniProtKB/TrEMBL),   A0A8C0PSR6 (UniProtKB/TrEMBL),   A0A8I3MFF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038383323   ⟸   XM_038527395
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KL72 (UniProtKB/TrEMBL),   A0A8C0M0E3 (UniProtKB/TrEMBL),   A0A8C0PSF6 (UniProtKB/TrEMBL),   A0A8I3M9Y6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038383324   ⟸   XM_038527396
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KL72 (UniProtKB/TrEMBL),   A0A8C0M0E3 (UniProtKB/TrEMBL),   A0A8C0PSF6 (UniProtKB/TrEMBL),   A0A8I3M9Y6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038383322   ⟸   XM_038527394
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KL72 (UniProtKB/TrEMBL),   A0A8C0M0E3 (UniProtKB/TrEMBL),   A0A8C0PSF6 (UniProtKB/TrEMBL),   A0A8I3M9Y6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845000131   ⟸   ENSCAFT00845000170
RefSeq Acc Id: ENSCAFP00845000126   ⟸   ENSCAFT00845000164
RefSeq Acc Id: ENSCAFP00845000134   ⟸   ENSCAFT00845000175
Protein Domains
Aminoacyl-tRNA synthetase class Ia   Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000002340 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030001048 UniProtKB/TrEMBL
  ENSCAFG00040001933 UniProtKB/TrEMBL
  ENSCAFG00845000092 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000003663.5 UniProtKB/TrEMBL
  ENSCAFT00000080250.2 UniProtKB/TrEMBL
  ENSCAFT00000100370.1 UniProtKB/TrEMBL
  ENSCAFT00000105469.1 UniProtKB/TrEMBL
  ENSCAFT00030001808.1 UniProtKB/TrEMBL
  ENSCAFT00030001882.1 UniProtKB/TrEMBL
  ENSCAFT00030001973.1 UniProtKB/TrEMBL
  ENSCAFT00040003686.1 UniProtKB/TrEMBL
  ENSCAFT00040003751.1 UniProtKB/TrEMBL
  ENSCAFT00040003806.1 UniProtKB/TrEMBL
  ENSCAFT00040003854.1 UniProtKB/TrEMBL
  ENSCAFT00040003911.1 UniProtKB/TrEMBL
  ENSCAFT00845000164.1 UniProtKB/TrEMBL
  ENSCAFT00845000170 ENTREZGENE
  ENSCAFT00845000170.1 UniProtKB/TrEMBL
  ENSCAFT00845000175 ENTREZGENE
  ENSCAFT00845000175.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.620 UniProtKB/TrEMBL
  3.90.740.10 UniProtKB/TrEMBL
InterPro aa-tRNA-synth_I_CS UniProtKB/TrEMBL
  aa-tRNA-synth_Ia UniProtKB/TrEMBL
  Anticodon_Ile_ABEc UniProtKB/TrEMBL
  Ile-tRNA-ligase UniProtKB/TrEMBL
  Ile-tRNA-ligase_type2 UniProtKB/TrEMBL
  M/V/L/I-tRNA-synth_anticd-bd UniProtKB/TrEMBL
  Rossmann-like_a/b/a_fold UniProtKB/TrEMBL
  tRNAsynth_Ia_anticodon-bd UniProtKB/TrEMBL
  Val/Leu/Ile-tRNA-synth_edit UniProtKB/TrEMBL
KEGG Report cfa:484216 UniProtKB/TrEMBL
NCBI Gene IARS ENTREZGENE
PANTHER ISOLEUCINE--TRNA LIGASE, CYTOPLASMIC UniProtKB/TrEMBL
  PTHR42780 UniProtKB/TrEMBL
Pfam Anticodon_1 UniProtKB/TrEMBL
  DUF5915 UniProtKB/TrEMBL
  tRNA-synt_1 UniProtKB/TrEMBL
PRINTS TRNASYNTHILE UniProtKB/TrEMBL
PROSITE AA_TRNA_LIGASE_I UniProtKB/TrEMBL
Superfamily-SCOP Nucleotidylyl transferase UniProtKB/TrEMBL
  SSF47323 UniProtKB/TrEMBL
  SSF50677 UniProtKB/TrEMBL
UniProt A0A8C0KL72 ENTREZGENE
  A0A8C0LU04_CANLF UniProtKB/TrEMBL
  A0A8C0M0E3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0M0Q7_CANLF UniProtKB/TrEMBL
  A0A8C0PSF6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0PSM5_CANLF UniProtKB/TrEMBL
  A0A8C0PSR6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3M9Y6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MFF7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RNX5_CANLF UniProtKB/TrEMBL
  A0A8P0PLH8_CANLF UniProtKB/TrEMBL
UniProt Secondary A0A8P0NZT4 UniProtKB/TrEMBL
VGNC ID VGNC:41849 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-08-06 IARS1  isoleucyl-tRNA synthetase 1  IARS  isoleucyl-tRNA synthetase  Symbol and/or name change 5135510 APPROVED