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ONTOLOGY REPORT - ANNOTATIONS

Term:transmembrane signaling receptor activity
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Accession:GO:0004888 term browser browse the term
Definition:Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.
Comment:This term includes intracellular membrane receptors, e.g. IP3 triggered release of Ca2+ from intracellular stores.
Synonyms:exact_synonym: transmembrane signalling receptor activity
 broad_synonym: transmembrane receptor activity
 alt_id: GO:0004926;   GO:0099600
 xref: reactome:R-HSA-193672 "Sphingomyelinase is activated by the NGF:p75NTR complex"

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      molecular_function 189412
        molecular transducer activity 17507
          signaling receptor activity 17507
            transmembrane signaling receptor activity 15568
              G protein-coupled receptor activity + 10651
              GABA receptor activity + 218
              ICAM-3 receptor activity 22
              MHC class I receptor activity + 89
              MHC class II receptor activity 20
              MHC class Ib receptor activity + 43
              Wnt receptor activity 173
              acetylcholine receptor activity + 192
              apolipoprotein A-I receptor activity 20
              axon guidance receptor activity 142
              collagen receptor activity + 60
              complement receptor activity + 107
              cytokine receptor activity + 985
              cytokinin receptor activity + 0
              death receptor activity + 90
              glutamate receptor activity + 264
              hedgehog receptor activity 28
              immunoglobulin receptor activity + 103
              latrotoxin receptor activity 12
              mechanoreceptor activity 0
              netrin receptor activity + 58
              neuregulin receptor activity 31
              neurotensin receptor activity, non-G protein-coupled 10
              non-tyrosine kinase fibroblast growth factor receptor activity 1
              nucleotide receptor activity + 195
              olfactory receptor activity + 7389
              opsonin receptor activity + 51
              osmosensor activity + 58
              reelin receptor activity 20
              semaphorin receptor activity 120
              serotonin receptor activity + 52
              sulfonylurea receptor activity 20
              taste receptor activity + 271
              tiggrin receptor activity 0
              transmembrane receptor protein kinase activity + 756
              transmembrane receptor protein phosphatase activity + 55
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