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ONTOLOGY REPORT - ANNOTATIONS

Term:neuregulin receptor activity
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Accession:GO:0038131 term browser browse the term
Definition:Combining with a neuregulin, a member of the EGF family of growth factors, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
Comment:Consider also annotating to 'ERBB3 signaling pathway ; GO:0038129' and/or 'ERBB4 signaling pathway ; GO:0038130'.
Synonyms:exact_synonym: NRG receptor activity
 narrow_synonym: NRG1 receptor activity;   NRG2 receptor activity


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neuregulin receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Erbb3 erb-b2 receptor tyrosine kinase 3 enables IMP
IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000117
MGI:1929598|MGI:96083 (PMID:10521398), (PMID:18760695), (PMID:8653787) 		GO_Central
UniProt
RGD		 PMID:8653787 PMID:10521398 PMID:18760695 PMID:14711829 GO_REF:0000033 GO_REF:0000117, RGD:2289958 NCBI chr 7:1,579,079...1,600,379
Ensembl chr 7:1,579,816...1,601,120 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 enables IDA
ISO
IEA 		PMID:26027736
(PMID:12466964), (PMID:9275162)
GO_REF:0000107
GO_REF:0000117
MGI:2680217 (PMID:19632177), (PMID:23033483), (PMID:9168115)
(PMID:28822966), (PMID:8702723) 		RGD
Ensembl
UniProt		 PMID:8702723 PMID:9168115 PMID:9275162 PMID:12466964 PMID:19632177 More... GO_REF:0000107 GO_REF:0000117, RGD:11052272 NCBI chr 9:76,973,386...78,045,633
Ensembl chr 9:76,973,227...78,045,772 		JBrowse link
G Rtn4r reticulon 4 receptor enables ISS
ISO 		GO_REF:0000024
(PMID:22923615) 		UniProt
RGD		 PMID:22923615 GO_REF:0000024 NCBI chr11:96,348,613...96,373,554
Ensembl chr11:96,348,502...96,373,554 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19971
    molecular transducer activity 2528
      signaling receptor activity 2528
        transmembrane signaling receptor activity 2253
          neuregulin receptor activity 3
paths to the root