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ONTOLOGY REPORT - ANNOTATIONS

Term:serotonin receptor activity
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Accession:GO:0099589 term browser browse the term
Definition:Combining with the biogenic amine serotonin and transmitting a signal across a membrane by activating some effector activity. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.


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serotonin receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1f 5-hydroxytryptamine receptor 1F enables IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr11:16,089,266...16,090,665
Ensembl chr11:16,081,053...16,274,580 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A enables IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr15:56,360,647...56,428,703
Ensembl chr15:56,359,596...56,431,619 		JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B enables IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 9:94,184,442...94,206,851
Ensembl chr 9:94,190,109...94,204,087 		JBrowse link
G Htr4 5-hydroxytryptamine receptor 4 enables IEA
ISO 		GO_REF:0000107
(PMID:33481771) 		Ensembl
RGD		 PMID:33481771 GO_REF:0000107 NCBI chr18:58,036,277...58,221,327
Ensembl chr18:58,036,277...58,219,622 		JBrowse link
G Htr5a 5-hydroxytryptamine receptor 5A enables IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:8,178,802...8,188,485
Ensembl chr 4:8,178,802...8,200,482 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 enables IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 1:243,049,064...243,173,636
Ensembl chr 1:243,049,081...243,173,230 		JBrowse link
serotonin-gated monoatomic cation channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrna10 cholinergic receptor nicotinic alpha 10 subunit enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:165,898,932...165,905,348
Ensembl chr 1:165,899,261...165,903,458 		JBrowse link
G Chrna9 cholinergic receptor nicotinic alpha 9 subunit enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:42,588,948...42,595,669
Ensembl chr14:42,588,948...42,595,669 		JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A enables IDA
ISO
IBA
IEA 		(PMID:10521471), (PMID:7565620), (PMID:9950429)
GO_REF:0000033
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:7565620 PMID:9950429 PMID:10521471 PMID:12196560 GO_REF:0000033 GO_REF:0000107, RGD:625614 NCBI chr 8:58,138,514...58,150,960
Ensembl chr 8:58,138,226...58,150,884 		JBrowse link
G Htr3b 5-hydroxytryptamine receptor 3B enables IEA
ISO
IBA
IDA 		GO_REF:0000107
(PMID:10854267)
GO_REF:0000117
GO_REF:0000033
UniProtKB:P46098 (PMID:7565620), (PMID:9950429) 		Ensembl
RGD
UniProt
GO_Central		 PMID:7565620 PMID:9950429 PMID:10854267 PMID:10854267 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117, RGD:61635 NCBI chr 8:58,175,785...58,204,939
Ensembl chr 8:58,175,101...58,204,939 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19971
    molecular transducer activity 2528
      signaling receptor activity 2528
        transmembrane signaling receptor activity 2253
          serotonin receptor activity 10
            serotonin-gated chloride channel activity 0
            serotonin-gated monoatomic cation channel activity 4
paths to the root