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ONTOLOGY REPORT - ANNOTATIONS

Term:death receptor activity
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Accession:GO:0005035 term browser browse the term
Definition:Combining with an extracellular messenger (called a death ligand), and transmitting the signal from one side of the plasma membrane to the other to initiate apoptotic or necrotic cell death.
Synonyms:related_synonym: apoptosis-activating receptor activity


show annotations for term's descendants           Sort by:
death receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ngfr nerve growth factor receptor enables IEA
ISO
IBA		 GO_REF:0000107
UniProtKB:P01138-PRO_0000019600|UniProtKB:P05067-PRO_0000000092 (PMID:11927634)
GO_REF:0000033
(PMID:10764727)		 Ensembl
RGD
GO_Central		 PMID:10764727 PMID:11927634 GO_REF:0000033 GO_REF:0000107 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Nradd neurotrophin receptor associated death domain enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:110,599,667...110,603,068
Ensembl chr 8:110,599,667...110,603,149 		JBrowse link
tumor necrosis factor receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eda2r ectodysplasin A2 receptor enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:62,224,763...62,269,333
Ensembl chr  X:62,228,229...62,269,268 		JBrowse link
G Fas Fas cell surface death receptor enables IMP
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:16154149 GO_REF:0000033, RGD:1582433 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A enables ISO
IBA		 (MGI:4413614|PMID:19940926)
GO_REF:0000033		 RGD
GO_Central		 PMID:19940926 GO_REF:0000033 MGI:4413614 NCBI chr13:21,928,370...21,986,719
Ensembl chr13:21,928,408...21,986,695 		JBrowse link
G Tnfrsf18 TNF receptor superfamily member 18 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:166,618,461...166,622,353
Ensembl chr 5:166,618,969...166,622,353 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A enables IMP
ISO
IBA
IEA
ISS		 MGI:1861040|UniProtKB:P01374|UniProtKB:P01375|UniProtKB:P06804 (PMID:11588035), (PMID:14985352), (PMID:1645445), (PMID:1647956)
GO_REF:0000033
(PMID:26183779)
GO_REF:0000002
GO_REF:0000024		 RGD
GO_Central
InterPro
UniProt		 PMID:1645445 PMID:1647956 PMID:11588035 PMID:14985352 PMID:26183779 More... GO_REF:0000002 GO_REF:0000024 GO_REF:0000033, RGD:5130976 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B enables IDA
ISO
IBA
IEA		 UniProtKB:P01374|UniProtKB:P06804 (PMID:1645445)
GO_REF:0000033
GO_REF:0000002		 RGD
GO_Central
InterPro		 PMID:1645445 PMID:12376316 GO_REF:0000002 GO_REF:0000033, RGD:628388 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 enables TAS
ISO
IBA		 UniProtKB:P43488 (PMID:14635034)
GO_REF:0000033		 RGD
GO_Central		 PMID:14635034 PMID:2157591 GO_REF:0000033, RGD:70044 NCBI chr 5:166,606,909...166,609,599
Ensembl chr 5:166,606,909...166,609,599 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20733
    molecular transducer activity 2601
      signaling receptor activity 2601
        transmembrane signaling receptor activity 2399
          death receptor activity 9
            TRAIL receptor activity 0
            tumor necrosis factor receptor activity 7
paths to the root